KEGG   Cercocebus atys (sooty mangabey): 105571365
Entry
105571365         CDS       T07242                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty04010  MAPK signaling pathway
caty04020  Calcium signaling pathway
caty04022  cGMP-PKG signaling pathway
caty04114  Oocyte meiosis
caty04218  Cellular senescence
caty04310  Wnt signaling pathway
caty04360  Axon guidance
caty04370  VEGF signaling pathway
caty04380  Osteoclast differentiation
caty04625  C-type lectin receptor signaling pathway
caty04650  Natural killer cell mediated cytotoxicity
caty04658  Th1 and Th2 cell differentiation
caty04659  Th17 cell differentiation
caty04660  T cell receptor signaling pathway
caty04662  B cell receptor signaling pathway
caty04720  Long-term potentiation
caty04724  Glutamatergic synapse
caty04728  Dopaminergic synapse
caty04921  Oxytocin signaling pathway
caty04922  Glucagon signaling pathway
caty04924  Renin secretion
caty05010  Alzheimer disease
caty05014  Amyotrophic lateral sclerosis
caty05020  Prion disease
caty05022  Pathways of neurodegeneration - multiple diseases
caty05031  Amphetamine addiction
caty05152  Tuberculosis
caty05163  Human cytomegalovirus infection
caty05166  Human T-cell leukemia virus 1 infection
caty05167  Kaposi sarcoma-associated herpesvirus infection
caty05170  Human immunodeficiency virus 1 infection
caty05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
caty05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:caty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105571365 (PPP3CA)
   04310 Wnt signaling pathway
    105571365 (PPP3CA)
   04370 VEGF signaling pathway
    105571365 (PPP3CA)
   04020 Calcium signaling pathway
    105571365 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    105571365 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    105571365 (PPP3CA)
   04218 Cellular senescence
    105571365 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    105571365 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    105571365 (PPP3CA)
   04660 T cell receptor signaling pathway
    105571365 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    105571365 (PPP3CA)
   04659 Th17 cell differentiation
    105571365 (PPP3CA)
   04662 B cell receptor signaling pathway
    105571365 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    105571365 (PPP3CA)
   04921 Oxytocin signaling pathway
    105571365 (PPP3CA)
   04924 Renin secretion
    105571365 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    105571365 (PPP3CA)
   04728 Dopaminergic synapse
    105571365 (PPP3CA)
   04720 Long-term potentiation
    105571365 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    105571365 (PPP3CA)
   04380 Osteoclast differentiation
    105571365 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105571365 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105571365 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    105571365 (PPP3CA)
   05163 Human cytomegalovirus infection
    105571365 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105571365 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    105571365 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105571365 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    105571365 (PPP3CA)
   05020 Prion disease
    105571365 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    105571365 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    105571365 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105571365 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:caty01009]
    105571365 (PPP3CA)
Enzymes [BR:caty01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     105571365 (PPP3CA)
Protein phosphatases and associated proteins [BR:caty01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     105571365 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 105571365
NCBI-ProteinID: XP_011884248
Ensembl: ENSCATG00000012154
UniProt: A0A2K5KRZ9
LinkDB
Position
Unknown
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcctaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcacatcttatgaaggagggaagactggaagagagtgtt
gcattgagaataataacagagggtgcatcaattcttcgacaggaaaaaaacttgctggat
attgatgcgccagtcacagtttgtggggacattcatggacaattctttgacttgatgaag
ctctttgaagtcgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgacgcctgtatggat
gcctttgactgccttcccttggctgccctgatgaaccaacagttcctgtgtgtacatggt
ggcttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcatatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcgtacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatacttcgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacagggtttcct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtccctgccttttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctctgatgatgaactagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaggaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccgactggcatgctccccagcggagtactttctggaggg
aagcaaaccctacaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

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