KEGG   Cercocebus atys (sooty mangabey): 105572871
Entry
105572871         CDS       T07242                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty04010  MAPK signaling pathway
caty04022  cGMP-PKG signaling pathway
caty04137  Mitophagy - animal
caty04141  Protein processing in endoplasmic reticulum
caty04151  PI3K-Akt signaling pathway
caty04210  Apoptosis
caty04211  Longevity regulating pathway
caty04261  Adrenergic signaling in cardiomyocytes
caty04668  TNF signaling pathway
caty04720  Long-term potentiation
caty04722  Neurotrophin signaling pathway
caty04725  Cholinergic synapse
caty04728  Dopaminergic synapse
caty04911  Insulin secretion
caty04912  GnRH signaling pathway
caty04915  Estrogen signaling pathway
caty04918  Thyroid hormone synthesis
caty04922  Glucagon signaling pathway
caty04925  Aldosterone synthesis and secretion
caty04926  Relaxin signaling pathway
caty04927  Cortisol synthesis and secretion
caty04928  Parathyroid hormone synthesis, secretion and action
caty04932  Non-alcoholic fatty liver disease
caty04934  Cushing syndrome
caty04935  Growth hormone synthesis, secretion and action
caty05010  Alzheimer disease
caty05012  Parkinson disease
caty05014  Amyotrophic lateral sclerosis
caty05020  Prion disease
caty05022  Pathways of neurodegeneration - multiple diseases
caty05030  Cocaine addiction
caty05031  Amphetamine addiction
caty05034  Alcoholism
caty05161  Hepatitis B
caty05163  Human cytomegalovirus infection
caty05166  Human T-cell leukemia virus 1 infection
caty05203  Viral carcinogenesis
caty05207  Chemical carcinogenesis - receptor activation
caty05215  Prostate cancer
caty05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:caty00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    105572871 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105572871 (ATF4)
   04668 TNF signaling pathway
    105572871 (ATF4)
   04022 cGMP-PKG signaling pathway
    105572871 (ATF4)
   04151 PI3K-Akt signaling pathway
    105572871 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    105572871 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    105572871 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105572871 (ATF4)
   04922 Glucagon signaling pathway
    105572871 (ATF4)
   04912 GnRH signaling pathway
    105572871 (ATF4)
   04915 Estrogen signaling pathway
    105572871 (ATF4)
   04926 Relaxin signaling pathway
    105572871 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    105572871 (ATF4)
   04918 Thyroid hormone synthesis
    105572871 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    105572871 (ATF4)
   04925 Aldosterone synthesis and secretion
    105572871 (ATF4)
   04927 Cortisol synthesis and secretion
    105572871 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105572871 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    105572871 (ATF4)
   04728 Dopaminergic synapse
    105572871 (ATF4)
   04720 Long-term potentiation
    105572871 (ATF4)
   04722 Neurotrophin signaling pathway
    105572871 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    105572871 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    105572871 (ATF4)
   05203 Viral carcinogenesis
    105572871 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    105572871 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105572871 (ATF4)
   05161 Hepatitis B
    105572871 (ATF4)
   05163 Human cytomegalovirus infection
    105572871 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105572871 (ATF4)
   05012 Parkinson disease
    105572871 (ATF4)
   05014 Amyotrophic lateral sclerosis
    105572871 (ATF4)
   05020 Prion disease
    105572871 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    105572871 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    105572871 (ATF4)
   05031 Amphetamine addiction
    105572871 (ATF4)
   05034 Alcoholism
    105572871 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105572871 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    105572871 (ATF4)
   04934 Cushing syndrome
    105572871 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:caty03000]
    105572871 (ATF4)
Transcription factors [BR:caty03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    105572871 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF3450 DUF4407 Asd-4 Nop53 AAA_13 OVT1 Laminin_II
Other DBs
NCBI-GeneID: 105572871
NCBI-ProteinID: XP_011887173
Ensembl: ENSCATG00000030431
UniProt: A0A2K5LHU8
LinkDB
Position
Unknown
AA seq 351 aa
MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFRPHGFSSDKAKAGSSE
WLAVDGLVSPSNNGKEDAFSGTDWMLEKMDLKEFDFDALLGIDDLETMPDDLLTTLDDTC
DLFAPLVQETNKEPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
ELGSEVDITEGDRKPDATAYVAVMPPCIKEEDSPSDNDSGICMSPESYLGSPQHSPSTRG
SPNRSLPSPGVLCGSARPKPYDPPGEKMVEAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgaccgaaatgagcttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagcctaggtctcttagatgactacctggaggtg
gccaagcacttcagacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtccctccaacaacggcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatttgaaggagttcgactttgatgccctgttg
ggtatagatgacctggaaaccatgccagatgaccttttgaccacgttggatgacacgtgt
gatctctttgcccccctagtccaagagactaacaaggagcccccccagacggtgaaccca
attggccatctcccagaaagtttaacaaaacccgaccaggttgcccccttcaccttcttg
caacctcttcccctttccccaggggtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatcactgaaggagataggaagccagatgccactgcttat
gttgccgtgatgcctccgtgcataaaggaggaagacagcccctcagataatgatagtggc
atctgtatgagcccggagtcctatctgggctctcctcagcatagcccgtccaccaggggc
tctccaaataggagcctcccgtctccaggtgttctctgtggttctgcccgccccaaacct
tacgaccctcctggagagaagatggtagaagcaaaagtaaagggtgagaaactggataag
aagctgaaaaaaatggagcaaaacaagacagcagccactaggtaccgccagaagaagagg
gcggagcaggaggccctcactggcgagtgcaaagagctggaaaagaagaatgaggcttta
aaagagagggcggattccctggccaaggagatccagtacctgaaagatttgatagaagag
gtccgcaaggcaagggggaagaaaagggtcccctag

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