Cercocebus atys (sooty mangabey): 105574031
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Entry
105574031 CDS
T07242
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty00230
Purine metabolism
caty01100
Metabolic pathways
caty04927
Cortisol synthesis and secretion
caty04934
Cushing syndrome
caty05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105574031 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
105574031 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
105574031 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105574031 (PDE8A)
Enzymes [BR:
caty01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
105574031 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PAS_4
PAS_3
PDE8
PAS_8
DUF5894
Sina_ZnF
Motif
Other DBs
NCBI-GeneID:
105574031
NCBI-ProteinID:
XP_011889954
Ensembl:
ENSCATG00000030845
LinkDB
All DBs
Position
Unknown
AA seq
835 aa
AA seq
DB search
MGCAPSIHISESLEAEDAPSPAASPLSSGGPRLPQGQKTAALSRTRGAGLLELEPRDGSG
KKVAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACF
LDKHHDIIIIDHRNPRQLDAEALCSFVFFLRSIRSSKLSENTVIVGVVRRVDREELSVMP
FIAAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSED
RVIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSCIRIGKEWQGIYYAKK
KNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKIPECVQSDTQTDNQTGKHKD
RRKGSLDVKAVASRTTEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEA
LDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNTQTVSSN
IITPISLDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCS
ESTLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAAT
IHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDY
RTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEEDGETDKNQEMINTMLRTPENR
TLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSI
PKSQISFIDYFITDMFDAWDAFLDLPDLMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2508 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgccccgagcatccacatttctgagagcctggaggccgaggacgcacctagc
cccgcggcatcgccgctgtcgtccggcgggccgcgcctccctcagggccagaagacggcc
gccttgtcccggacccgcggcgccggcctcttggagttggagcctcgcgacggcagcggc
aagaaggtagcagtagctgatgtgcaatttggccccatgagatttcatcaagatcaactt
caggtacttttagtgtttaccaaagaagataaccaatgtaatggattctgcagggcatgt
gaaaaagcagggtttaagtgtacagttaccaaggaggctcaggctgtccttgcctgtttc
ctggacaaacatcatgacattatcatcatagaccacagaaatcctcgacaactggatgca
gaggcactgtgcagttttgtgttttttttaaggtctatcagatcatcaaaactctcagaa
aacacagttattgttggtgtagtacgcagggtggatagagaagagttgtccgtaatgcct
ttcattgctgctggatttacaaggaggtatgtggaaaaccccaacatcatggcctgctac
aatgaactgctccagctggagtttggagaggtgcgatcacaactgaaactcagggcttgt
aactctgtattcactgcattagaaaacagtgaagatgcaattgaaattacaagtgaagac
cgtgttatacagtatgcaaatcctgcatttgaaacaacaatgggctatcagtcaggtgaa
ttaatagggaaggagttaggagaagtgcctataaatgaaaaaaaggctgacttgctcgat
actataaattcatgcatcaggataggcaaggagtggcaaggaatttactatgccaaaaag
aaaaacggagataatatacaacaaaatgtgaagataatacctgtcattggacagggagga
aaaattagacactatgtgtccattatcagagtgtgcaatggcaacaataaggctgagaaa
atacccgaatgtgttcagtctgacactcaaacagataatcagacaggcaaacataaagac
agaagaaaaggctcactagacgtcaaagctgttgcctcccgtacaactgaagtttccagc
cagagacgacactcttctatggcccggatacattccatgacgattgaggcgcccatcacc
aaggtaatcaatattatcaatgctgcccaggaaagtagtcccatgcctgtgaccgaagcc
ctagaccgtgtgctggaaattctaagaaccactgagttatattcaccacagtttggtgct
aaggatgatgatccccatgccaatgaccttgttgggggcttaatgtctgatggtttgcga
agactatcagggaatgaatatgttctttcaacaaaaaacactcaaacggtttcaagcaat
ataatcactcccatctcccttgatgatgtcccaccacggatagctcgggccatggaaaat
gaggaatactgggactttgatatttttgaactggaggctgccacccacaataggcctttg
atttatcttggtctcaaaatgtttgctcgctttggaatctgtgaattcttacactgctct
gagtcaacactaagatcatggttacaaattatcgaagccaattatcattcttccaatccc
taccacaattctacacattctgctgatgtgcttcatgccactgcctattttctctccaag
gagaggataaaggaaactttagatccaattgatgaggtcgctgcactcattgcagccacc
attcatgatgtggatcaccctgggagaaccaactccttcctgtgtaatgctggaagtgag
ctggccattttgtacaatgacactgctgtgctggagagccaccatgcggccttggccttc
cagctgaccactggagatgataaatgcaatatatttaaaaacatggagaggaatgactat
cggacactgcgccagggaattatcgacatggtcttagccacggaaatgacaaagcacttt
gagcatgtcaacaaatttgtcaacagcatcaacaaacccttggcaacgctagaagaagac
ggggaaactgataaaaatcaggaaatgataaacactatgcttaggactccagagaaccgg
actctaatcaaacgaatgctgattaaatgtgctgatgtgtccaatccttgccgacccctg
cagtactgcatcgagtgggctgcacgcatttcagaagaatatttttcgcagactgatgaa
gagaagcagcaggacttacctgtggtaatgccagtttttgacagaaatacctgcagcatc
cccaaatcccaaatctctttcattgattacttcatcacagacatgtttgatgcttgggat
gcctttctagacctgcctgatttaatgcagcatcttgacaacaactttaaatactggaaa
ggattggacgaaatgaagctgcggagcctccgaccacctcctgaatag
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