Cercocebus atys (sooty mangabey): 105576250
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Entry
105576250 CDS
T07242
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty00790
Folate biosynthesis
caty01100
Metabolic pathways
caty01240
Biosynthesis of cofactors
caty01523
Antifolate resistance
caty04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
105576250 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
105576250 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105576250 (FPGS)
Enzymes [BR:
caty01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
105576250 (FPGS)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
105576250
NCBI-ProteinID:
XP_011894445
Ensembl:
ENSCATG00000010665
LinkDB
All DBs
Position
Unknown
AA seq
588 aa
AA seq
DB search
MSRARNHLRAALFLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEALEEGGPPLALGLDGE
HQRSNAALALQLAHCWLQRQDRHGAGEVKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
LGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFRQALQGRERPSGSGPEVRVLLFNATGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDE
EQASPDLWSAPSPEPGGPTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPVFQPPT
PPKGLLTHPVAHSGASVLHEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggaaccacctgcgcgccgctctattcctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgcatgcttaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacttgtgccttcacggaatgtatcctccgaagc
tatggcctgaaaacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaacgggcagcccatcagtcccgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcggc
gtctcttctcttggcatcgaccacaccagcctcctgggggacacggtggagaagatcgca
tggcagaaagggggcatctttaagcaaggcgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctctacctgtgt
ccgacgctggaggccctggaggaaggggggccgccgctggccctgggcctggacggggag
caccagcggtccaacgccgccttggccttgcaactggcccactgctggctgcagcggcag
gaccgccatggtgccggggaggtgaaggcatccaggccggggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggcttgggcttcggaacacggagtgg
ctggggcggacacaggtgttgcggcgcgggccccttacctggtacctggacggcgcgcac
acccccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcagggccgagaa
aggccgagcggcagtgggcccgaggttcgagtcttgctcttcaatgctaccggggaccgg
gacccggcggccttgctgaaactgctgcagccgtgccagtttgactatgccgtcttctgc
cccaacctgacagaggtgtcatccacaggcaatgcagaccaacagaacttcacggtgaca
ctggaccaggttctgctccgctgcctggaacaccagcagcactggaaccacctggacgaa
gagcaggccagcccggacctctggagcgcccccagcccagagcctggtgggcccacatcc
ctactgctggcgccccacccaccccacacctgcagcgccagctccctcgtcttcagctgt
atttcacatgccttgcaatggatcagccaaggccgagaccctgtcttccagccacccact
cccccaaagggcctcctcacccaccctgtggctcacagtggggccagcgtactccatgag
gctgctgccatccatgtgctggtcactggcagcctgcacctggtgggtggtgtcctgaag
ctgctggagcctgcactgtcccagtaa
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