KEGG   Cercocebus atys (sooty mangabey): 105577361
Entry
105577361         CDS       T07242                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty03015  mRNA surveillance pathway
caty04022  cGMP-PKG signaling pathway
caty04024  cAMP signaling pathway
caty04114  Oocyte meiosis
caty04218  Cellular senescence
caty04261  Adrenergic signaling in cardiomyocytes
caty04270  Vascular smooth muscle contraction
caty04390  Hippo signaling pathway
caty04510  Focal adhesion
caty04519  Cadherin signaling
caty04611  Platelet activation
caty04720  Long-term potentiation
caty04728  Dopaminergic synapse
caty04750  Inflammatory mediator regulation of TRP channels
caty04810  Regulation of actin cytoskeleton
caty04910  Insulin signaling pathway
caty04921  Oxytocin signaling pathway
caty04931  Insulin resistance
caty05031  Amphetamine addiction
caty05034  Alcoholism
caty05168  Herpes simplex virus 1 infection
caty05205  Proteoglycans in cancer
caty05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:caty00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    105577361 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    105577361 (PPP1CA)
   04024 cAMP signaling pathway
    105577361 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    105577361 (PPP1CA)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    105577361 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    105577361 (PPP1CA)
   04218 Cellular senescence
    105577361 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105577361 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105577361 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105577361 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105577361 (PPP1CA)
   04921 Oxytocin signaling pathway
    105577361 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105577361 (PPP1CA)
   04270 Vascular smooth muscle contraction
    105577361 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    105577361 (PPP1CA)
   04720 Long-term potentiation
    105577361 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105577361 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105577361 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    105577361 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    105577361 (PPP1CA)
   05034 Alcoholism
    105577361 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    105577361 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    105577361 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:caty01009]
    105577361 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:caty03021]
    105577361 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:caty03019]
    105577361 (PPP1CA)
   03041 Spliceosome [BR:caty03041]
    105577361 (PPP1CA)
Enzymes [BR:caty01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     105577361 (PPP1CA)
Protein phosphatases and associated proteins [BR:caty01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     105577361 (PPP1CA)
Transcription machinery [BR:caty03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     105577361 (PPP1CA)
Messenger RNA biogenesis [BR:caty03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     105577361 (PPP1CA)
Spliceosome [BR:caty03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    105577361 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 105577361
NCBI-ProteinID: XP_011896872
Ensembl: ENSCATG00000031120
UniProt: A0A2K5LMN4
LinkDB
Position
Unknown
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgatagcgagaagctcaaccttgactcgatcatcgggcgcctgctagaagtgcag
ggctcgcggcctggcaagaatgtacagctgacagagaacgagatccgcggcctgtgcctg
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgatatacacggccagtactatgaccttctgcgactatttgagtatggcggt
ttccctccggagagcaactacctctttctgggggactatgtggacaggggcaagcagtcc
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaacttcttcctg
ctccgtgggaaccacgagtgcgccagcatcaaccgcatctacggtttctacgatgagtgc
aagagacgctacaacatcaaactgtggaagacgttcactgactgcttcaactgcctgccc
attgcggccatagtggacgaaaagatcttttgctgccacggaggcctctccccggacctg
cagtccatggagcagattcggcggatcatgcggcccacagacgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtctcttttacctttggagccgaggtggtggccaagttcctccacaagcacgac
ttggacctcatctgccgagcacaccaggtggtagaagatggctatgagttctttgccaag
cggcagctggtgacacttttctcagctcctaactactgtggcgagtttgacaatgctggc
gccatgatgagcgtggatgagaccctcatgtgctccttccagatcctcaagcccgccgac
aagaacaaggggaagtacgggcagttcagtggcctgaaccctggaggccggcccatcacc
ccaccccgcaattccgccaaagccaagaaatag

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