Cercocebus atys (sooty mangabey): 105579553
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Entry
105579553 CDS
T07242
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty01521
EGFR tyrosine kinase inhibitor resistance
caty01522
Endocrine resistance
caty01524
Platinum drug resistance
caty04010
MAPK signaling pathway
caty04012
ErbB signaling pathway
caty04020
Calcium signaling pathway
caty04066
HIF-1 signaling pathway
caty04151
PI3K-Akt signaling pathway
caty04510
Focal adhesion
caty04520
Adherens junction
caty04530
Tight junction
caty05200
Pathways in cancer
caty05205
Proteoglycans in cancer
caty05206
MicroRNAs in cancer
caty05212
Pancreatic cancer
caty05213
Endometrial cancer
caty05215
Prostate cancer
caty05219
Bladder cancer
caty05223
Non-small cell lung cancer
caty05224
Breast cancer
caty05226
Gastric cancer
caty05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105579553 (ERBB2)
04012 ErbB signaling pathway
105579553 (ERBB2)
04066 HIF-1 signaling pathway
105579553 (ERBB2)
04020 Calcium signaling pathway
105579553 (ERBB2)
04151 PI3K-Akt signaling pathway
105579553 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
105579553 (ERBB2)
04520 Adherens junction
105579553 (ERBB2)
04530 Tight junction
105579553 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105579553 (ERBB2)
05206 MicroRNAs in cancer
105579553 (ERBB2)
05205 Proteoglycans in cancer
105579553 (ERBB2)
05230 Central carbon metabolism in cancer
105579553 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
105579553 (ERBB2)
05226 Gastric cancer
105579553 (ERBB2)
05219 Bladder cancer
105579553 (ERBB2)
05215 Prostate cancer
105579553 (ERBB2)
05213 Endometrial cancer
105579553 (ERBB2)
05224 Breast cancer
105579553 (ERBB2)
05223 Non-small cell lung cancer
105579553 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105579553 (ERBB2)
01524 Platinum drug resistance
105579553 (ERBB2)
01522 Endocrine resistance
105579553 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
caty01001
]
105579553 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
caty04147
]
105579553 (ERBB2)
04090 CD molecules [BR:
caty04090
]
105579553 (ERBB2)
Enzymes [BR:
caty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105579553 (ERBB2)
Protein kinases [BR:
caty01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
105579553 (ERBB2)
Exosome [BR:
caty04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
105579553 (ERBB2)
CD molecules [BR:
caty04090
]
Proteins
105579553 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
ABC1
Tcell_CD4_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
105579553
NCBI-ProteinID:
XP_011901839
Ensembl:
ENSCATG00000022891
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPVCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLRVFETLEEITGYLYISAWPDSLP
DLSVLQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTRLCFVHTV
PWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARC
PSGVKPDLSYMPIWKFPDEEGTCQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVG
ILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGTGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPRAPSEG
TGSDVFDGDLGMGAAKGLQSLPAHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYV
NQPDVRPQPPSPQEGPLSPARPTGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPR
GGAAPQPHLPPAFSPAFDNLYYWDQDPSERGAPPSTFKGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcttgccccccggagct
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctccctgccagtcccgag
acccacctggacatgctccgccacctctaccagggctgccaggtggtgcagggtaacctg
gaactcacctacctgcccaccaatgccagcctctccttcctgcaggatatccaggaggta
cagggctacgtgctcatcgctcacaaccaagtgaggcaggtcccactgcagaggctgcgg
attgtgcgaggcacccagctctttgaggacaactatgccctggccgtgctagacaatgga
gacccgctgaacaataccacccctgtcacaggggcctccccaggaggcctgcgggagctg
cagcttcgaagcctcacagagatcttgaaaggaggggtcttgatccagcggaacccccag
ctctgctaccaggacacgattttgtggaaggacatcttccataagaacaaccagctggct
ctcacactgatcgacaccaaccgctctcgggcctgccacccctgttctccggtgtgtaag
ggctcccgctgctggggagagagttctgaggattgtcagagcttgacgcgcactgtctgt
gccggtggctgtgcccgctgcaaggggccactgcccactgactgctgccatgagcagtgt
gctgctggctgcacgggccccaagcactctgactgcctggcctgcctccacttcaaccac
agcggcatctgtgaactgcactgcccagccctggtcacctacaacacagacacctttgag
tccatgcccaaccccgagggccggtatacattcggcgccagctgtgtgactgcctgtccc
tacaactacctttctacggacgtgggatcctgtaccctcgtctgccccctgcacaaccaa
gaggtgacagcggaggacggaacacagcgatgtgagaagtgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggagcacttgcgagaggtgagggcggtcaccagtgccaat
atccaggagtttgctggctgcaagaagatctttgggagcttggcatttctgccagagagc
tttgatggcgacccagcctccaacaccgccccgcttcagccggagcagctccgagtgttt
gagactctggaagagatcacaggttacctatacatctcagcatggccagacagcctgcct
gaccttagcgtcctccagaacctgcaagtaatccggggacgaattctgcacaatggcgcc
tactcactgaccctgcaagggctgggcatcagctggctggggctgcgctcgctgagggaa
ctgggcagtggactggccctcatccaccataacactcgcctctgctttgtgcacacggtg
ccctgggaccagctcttccggaacccgcaccaagccctgctccacactgccaaccggcca
gaggacgagtgtgtgggcgagggcctggcctgccaccagctgtgcgcccgagggcactgc
tggggtccagggcccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctccccagggagtatgtgaatgccagacactgt
ttgccgtgccaccctgagtgtcagccccagaatggctcagtgacatgttttggaccggag
gctgaccagtgtgtggcctgtgcccactataaggaccctcccttctgcgtggcccgctgc
cccagcggtgtgaaacctgacctctcctacatgcccatctggaagtttccagatgaggag
ggcacgtgccagccttgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccccgccgagcagagagccagccctctgacgtccatcatctctgctgtggtgggc
attctgctggtcgtggtcttgggggtggtctttggaatcctcatcaagcgacggcagcag
aagatccggaagtacacgatgcggaggctgctgcaggaaacggagctggtggagccactg
acaccgagtggagcgatgcccaaccaggcgcagatgcggatcctgaaagagacggagctg
aggaaggtgaaggtgcttggatctggagcttttggcacagtctacaagggcatctggatc
cctgatggggagaatgtgaaaattccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttagacgaagcatacgtgatggctggtgtgggctccccg
tatgtctcccgcctcctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccatgttcgagaaaaccgcggacgcctgggctcccag
gacctgctgaactggtgtatgcagattgccaaggggatgagctacctggaggatgtgagg
ctcgtacacagggacttggctgctcggaacgtgctggtcaagagtcccaaccatgtcaaa
attacagactttgggctggctcggctgctggacattgacgagacagagtaccatgcagat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgacggcggttcacc
caccagagtgatgtgtggagttatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggaaaagggggagcgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgagattccgggagttggtgtcggaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccagccagtcccttg
gacagcaccttctaccgctcactgctggaggacgatgacatgggggacctggtggatgct
gaggagtatctggtaccccagcagggcttcttctgtccagaccctgccccgggcactggg
ggcatggtccaccacaggcaccgcagctcatctaccaggagtggcggtggggacctgacg
ctagggctggagccctctgaagaggaggcccccaggtctccacgggcaccctccgaaggg
actggctctgatgtatttgatggtgacctgggaatgggggcagccaaggggctgcaaagc
ctccccgcacatgaccccagccctctacagcggtacagtgaggatcccacggtacccctg
ccctctgagactgatggctacgttgcccccctgacctgcagtccccagcccgaatatgtg
aaccagccagatgttcggccacagcccccttcgccccaagagggccctctgtctcctgcc
cgacctactggtgccactctggaaaggcccaagactctctccccagggaagaatggggtt
gtcaaagacgtttttgcctttgggggtgctgtggagaaccccgagtacttggcaccccgg
ggaggggctgcccctcagccccaccttcctcctgccttcagcccagccttcgacaacctc
tattactgggaccaggacccatcagagcggggggctccacccagcaccttcaaagggaca
cctacggcagagaacccagagtacctgggtctggacgtgccagtgtga
DBGET
integrated database retrieval system
