KEGG   Cercocebus atys (sooty mangabey): 105580214
Entry
105580214         CDS       T07242                                 
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty00230  Purine metabolism
caty00670  One carbon pool by folate
caty01100  Metabolic pathways
caty01523  Antifolate resistance
Module
caty_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:caty00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    105580214 (ATIC)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    105580214 (ATIC)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105580214 (ATIC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:caty04147]
    105580214 (ATIC)
Enzymes [BR:caty01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     105580214 (ATIC)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     105580214 (ATIC)
Exosome [BR:caty04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   105580214 (ATIC)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS Ribosomal_L12_N
Other DBs
NCBI-GeneID: 105580214
NCBI-ProteinID: XP_011903317
Ensembl: ENSCATG00000033414
LinkDB
Position
Unknown
AA seq 594 aa
MAPGQLALFSVSDKTGLVEFARNLTSLGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMTRLDFNLIRVVACNLYPFVKTVASPGVTVEEA
VEQIDIGKSEKPFLQPKTMPRVTVCVNQRDYVASGPRDAELESKGHPPLETRRQYYALKA
FTHTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFI
NLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTP
ISTAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKK
NGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESAVRDL
IVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLLMKF
KTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISS
DAFFPFRDNVDRAKRSGVAYIAAPAGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq 1785 nt   +upstreamnt  +downstreamnt
atggctcctggccagctcgccttatttagtgtctctgacaaaaccggccttgtggaattt
gcaagaaacctgacctctcttggtttgaatctggtcgcttccggagggactgcaaaagct
ctcagggatgctggtctggcagtcagagatgtctccgagttgacgggatttcccgaaatg
ttggggggacgtgtgaaaactttgcatcctgcagtccatgctggaatcctggctcgtaat
atcccagaagataatgctgacatgaccagacttgatttcaatcttataagagttgttgcc
tgcaatctctatccctttgtgaagacagtggcttctccaggtgtaactgttgaggaggct
gtggagcaaattgacattggtaagtcagaaaaaccatttctgcagcccaaaaccatgcct
cgagtgacagtgtgtgtgaaccagagggactatgtggccagtggtccacgagatgcagag
ctcgagagtaagggccaccctcccttggagactagacgccagtattacgctttgaaggca
ttcactcatacggcacaatatgatgaagcaatttcagattatttcaggagacagtatagc
aaaggcatatctcagatgcccttgcgctatggaatgaaccctcatcagacccctgcccag
ctgtacacactgaagcccaagcttcccatcacagttctaaatggagcccctggatttata
aacttgtgcgatgctttgaacgcctggcaactggtgaaggaactcaaggaggcgttaggt
attccagccgctgcctctttcaaacatgtcagtccagcaggtgctgctgttggaattcca
ctcagtgaagatgaggccaaagtctgcatggtctatgatctctataaaaccctcacaccc
atttcaacagcatatgcaagagcaagaggggctgataggatgtcctcatttggtgatttt
gttgcattgtccgatgtttgtgatgtaccaactgcaaaaattatttccagagaagtatct
gatggtataattgccccaggatatgaagaagaagctttgacaatactttccaaaaagaaa
aatggaaattactgtgtccttcagatggaccagtcttacaaaccagatgaaaatgaagtt
cgaactctcttcggtcttcatttaagccagaagagaaataatggtgtcgtcgacaagtca
ttatttagcaatgttgttaccaagaataaagatttgccagagtcagccgtccgagacctc
atcgtagccaccattgctgtcaagtacactcagtctaactccgtgtgctacgccaagaat
gggcaggttatcggcattggagcaggacagcagtctcgtatacactgcactcgacttgca
ggagataaggcaaactattggtggcttagacaccatccacaagtgcttttgatgaagttt
aaaacaggagtgaagagagcagaaatctccaatgccatcgatcaatatgtgactggaacc
attggcgaggatgaagatttgatcaagtggaaggcattgtttgaggaagtccctgagtta
ctcactgaggcagagaagaaggaatgggttgagaaactgactgaagtttctatcagctct
gatgccttcttccctttcagagataatgtagacagagctaaaaggagtggtgtggcgtac
attgcggctcctgccggttctgctgctgacaaagttgtgattgaagcctgcgacgaactg
ggtatcatcctcgctcatacgaaccttcggctcttccaccactga

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