KEGG   Cercocebus atys (sooty mangabey): 105581389
Entry
105581389         CDS       T07242                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty04010  MAPK signaling pathway
caty04012  ErbB signaling pathway
caty04620  Toll-like receptor signaling pathway
caty04664  Fc epsilon RI signaling pathway
caty04668  TNF signaling pathway
caty04912  GnRH signaling pathway
caty04926  Relaxin signaling pathway
caty04935  Growth hormone synthesis, secretion and action
caty04936  Alcoholic liver disease
caty05132  Salmonella infection
caty05135  Yersinia infection
caty05142  Chagas disease
caty05161  Hepatitis B
caty05166  Human T-cell leukemia virus 1 infection
caty05167  Kaposi sarcoma-associated herpesvirus infection
caty05169  Epstein-Barr virus infection
caty05208  Chemical carcinogenesis - reactive oxygen species
caty05417  Lipid and atherosclerosis
caty05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:caty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105581389 (MAP2K4)
   04012 ErbB signaling pathway
    105581389 (MAP2K4)
   04668 TNF signaling pathway
    105581389 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105581389 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    105581389 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105581389 (MAP2K4)
   04926 Relaxin signaling pathway
    105581389 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    105581389 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    105581389 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105581389 (MAP2K4)
   05161 Hepatitis B
    105581389 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105581389 (MAP2K4)
   05169 Epstein-Barr virus infection
    105581389 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105581389 (MAP2K4)
   05135 Yersinia infection
    105581389 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    105581389 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105581389 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    105581389 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105581389 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:caty01001]
    105581389 (MAP2K4)
Enzymes [BR:caty01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105581389 (MAP2K4)
Protein kinases [BR:caty01001]
 Serine/threonine kinases: STE group
  STE7 family
   105581389 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 105581389
NCBI-ProteinID: XP_011905924
Ensembl: ENSCATG00000041493
UniProt: A0A2K5NJ62
LinkDB
Position
Unknown
AA seq 399 aa
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1200 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggccccgtagggtccccggcgccgggccacccggccgtcagcagcatgcagggtaaa
cgcaaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggtttact
ctgaatcccaatcctacaggagttcaaaacccacacatagagagactgagaacacacagc
attgagtcatcaggaaaactgaagatctcccctgaacaacactgggatttcactgcagag
gacttgaaagaccttggagaaattggacgaggagcttatggttctgtcaacaaaatggtc
cacaaaccaagtgggcaaataatggcagttaaaagaattcggtcaacggtggatgaaaaa
gaacaaaaacaacttcttatggatttggatgtagtaatgcggagtagtgattgcccatac
atcgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaactc
atgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgttatt
ccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccacttaaaa
gaaaacttgaaaattattcacagagatatcaaaccttccaatattcttctggacagaagt
ggaaatattaaactctgtgacttcggcatcagtggacagcttgtggactctattgccaag
acaagagatgctggctgtaggccatacatggcacctgaaagaatagacccaagcgcatct
cgacaaggatatgatgtccgctctgatgtctggagtttggggatcacattgtatgagttg
gccacaggccgatttccttatccaaagtggaatagtgtatttgatcaactaacacaagtc
gtgaaaggagatcctccgcagctgagtaattctgaggaaagggaattctccccaagtttc
atcaactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaagag
cttctgaaacatccctttattttgatgtatgaagaacgtgccgttgaggtcgcatgctat
gtttgtaaaatcctggatcaaatgccagctactcccagctctcccatgtatgtcgattga

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