KEGG   Cercocebus atys (sooty mangabey): 105582359
Entry
105582359         CDS       T07242                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty01521  EGFR tyrosine kinase inhibitor resistance
caty01522  Endocrine resistance
caty04012  ErbB signaling pathway
caty04015  Rap1 signaling pathway
caty04062  Chemokine signaling pathway
caty04081  Hormone signaling
caty04137  Mitophagy - animal
caty04144  Endocytosis
caty04360  Axon guidance
caty04370  VEGF signaling pathway
caty04510  Focal adhesion
caty04517  IgSF CAM signaling
caty04520  Adherens junction
caty04530  Tight junction
caty04540  Gap junction
caty04611  Platelet activation
caty04613  Neutrophil extracellular trap formation
caty04625  C-type lectin receptor signaling pathway
caty04727  GABAergic synapse
caty04750  Inflammatory mediator regulation of TRP channels
caty04810  Regulation of actin cytoskeleton
caty04912  GnRH signaling pathway
caty04915  Estrogen signaling pathway
caty04917  Prolactin signaling pathway
caty04919  Thyroid hormone signaling pathway
caty04921  Oxytocin signaling pathway
caty04926  Relaxin signaling pathway
caty05100  Bacterial invasion of epithelial cells
caty05135  Yersinia infection
caty05152  Tuberculosis
caty05161  Hepatitis B
caty05163  Human cytomegalovirus infection
caty05167  Kaposi sarcoma-associated herpesvirus infection
caty05168  Herpes simplex virus 1 infection
caty05203  Viral carcinogenesis
caty05205  Proteoglycans in cancer
caty05207  Chemical carcinogenesis - receptor activation
caty05208  Chemical carcinogenesis - reactive oxygen species
caty05219  Bladder cancer
caty05417  Lipid and atherosclerosis
caty05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:caty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    105582359 (SRC)
   04015 Rap1 signaling pathway
    105582359 (SRC)
   04370 VEGF signaling pathway
    105582359 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    105582359 (SRC)
   04517 IgSF CAM signaling
    105582359 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    105582359 (SRC)
   04137 Mitophagy - animal
    105582359 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105582359 (SRC)
   04520 Adherens junction
    105582359 (SRC)
   04530 Tight junction
    105582359 (SRC)
   04540 Gap junction
    105582359 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105582359 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105582359 (SRC)
   04613 Neutrophil extracellular trap formation
    105582359 (SRC)
   04625 C-type lectin receptor signaling pathway
    105582359 (SRC)
   04062 Chemokine signaling pathway
    105582359 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105582359 (SRC)
   04915 Estrogen signaling pathway
    105582359 (SRC)
   04917 Prolactin signaling pathway
    105582359 (SRC)
   04921 Oxytocin signaling pathway
    105582359 (SRC)
   04926 Relaxin signaling pathway
    105582359 (SRC)
   04919 Thyroid hormone signaling pathway
    105582359 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    105582359 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105582359 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    105582359 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105582359 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    105582359 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    105582359 (SRC)
   05203 Viral carcinogenesis
    105582359 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    105582359 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105582359 (SRC)
   05168 Herpes simplex virus 1 infection
    105582359 (SRC)
   05163 Human cytomegalovirus infection
    105582359 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105582359 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    105582359 (SRC)
   05152 Tuberculosis
    105582359 (SRC)
   05100 Bacterial invasion of epithelial cells
    105582359 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105582359 (SRC)
   05418 Fluid shear stress and atherosclerosis
    105582359 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105582359 (SRC)
   01522 Endocrine resistance
    105582359 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:caty01001]
    105582359 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:caty04131]
    105582359 (SRC)
Enzymes [BR:caty01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     105582359 (SRC)
Protein kinases [BR:caty01001]
 Non-receptor tyrosine kinases
  SRC family
   105582359 (SRC)
Membrane trafficking [BR:caty04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    105582359 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    105582359 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    105582359 (SRC)
  Macropinocytosis
   Kinases
    105582359 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase DUF7063
Other DBs
NCBI-GeneID: 105582359
NCBI-ProteinID: XP_011908194
Ensembl: ENSCATG00000014782
LinkDB
Position
Unknown
AA seq 633 aa
MDSDWRVDAIGISLSNDILKTVLRCLLYPCFADEDTEAQRGEVTCLGTHSGERWRRASSS
RPLTSHLVFVPRLQAASQVLWDSPCLLPARTMGSNKSKPKDASQRRRSLEPAENAHGAGG
GAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRTGPLAGGVTTF
VALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPS
DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK
HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAW
EIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHE
KLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERM
NYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFT
IKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWR
KEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1902 nt   +upstreamnt  +downstreamnt
atggacagtgattggagagtggatgccattgggatttctctttctaacgacatcctcaaa
acagtgctgagatgtctgctttatccctgctttgcagatgaggacactgaggcccagaga
ggggaagtcacttgcctagggacacacagcggggagaggtggaggagggcttctagttcg
agacccctgacttcacacctggtgtttgtgccaagactccaggctgcctcccaggtcctc
tgggacagcccctgccttctaccagccaggaccatgggcagcaacaagagcaagcccaag
gatgccagccagcggcgccgcagcctggagcccgccgagaacgcgcatggcgctggcggg
ggcgctttccccgcctcccagacccccagcaagccagcctcggccgacggccaccgcggc
cccagcgcggccttcgcccccgcggccgccgagcccaagctgttcggaggcttcaactcc
tcggacaccgtcacctccccgcagaggacgggcccgctggccggtggagtgaccaccttt
gtggccctctatgactatgagtctaggacggagacagacttgtccttcaagaaaggcgag
cggctccagattgtcaacaacacgaggaaggtggatgtcagagagggagactggtggctg
gcccactcgctcagcacgggacagacaggctacattcccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtattttggcaagatcaccagacgggagtcagagcgg
ttactgctcaatgcggagaacccgagagggaccttcctcgtgcgagaaagtgagaccaca
aaaggtgcctactgcctctcagtgtccgacttcgacaacgccaagggcctcaatgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaaacacgccgatggcctgtgccaccgc
ctcaccactgtgtgccccacatccaagcctcagactcagggcctggccaaggatgcctgg
gagatccctcgggagtcgctgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatggggacctggaacggcactaccagggtggccatcaaaaccctgaagcctggc
acgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaagctgaggcatgag
aagctggtgcagttgtatgctgtggtttcggaggagcccatttacatcgtcacagagtac
atgagcaaggggagtttgctggactttctcaagggggagacgggcaagtacctgcggctg
cctcagctggtggacatggctgctcagatcgcctcaggcatggcatacgtggagcggatg
aactacgtccaccgggatcttcgtgcagccaacatcctggtgggagagaacctggtgtgc
aaagtggccgactttgggctggctcggctcatcgaagacaatgagtacacggcccggcaa
ggtgccaaatttcccatcaagtggacagctccggaagctgccctgtatggccgcttcacc
atcaagtcggacgtgtggtcctttgggatcctgctgactgagctcaccacgaagggacgg
gtgccctaccctgggatggtgaaccgcgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccaccggagtgtcccgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggagcggcccaccttcgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggggagaacctctag

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