KEGG   Cercocebus atys (sooty mangabey): 105585586
Entry
105585586         CDS       T07242                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty04010  MAPK signaling pathway
caty04020  Calcium signaling pathway
caty04022  cGMP-PKG signaling pathway
caty04024  cAMP signaling pathway
caty04218  Cellular senescence
caty04260  Cardiac muscle contraction
caty04261  Adrenergic signaling in cardiomyocytes
caty04270  Vascular smooth muscle contraction
caty04530  Tight junction
caty04713  Circadian entrainment
caty04723  Retrograde endocannabinoid signaling
caty04724  Glutamatergic synapse
caty04725  Cholinergic synapse
caty04726  Serotonergic synapse
caty04727  GABAergic synapse
caty04728  Dopaminergic synapse
caty04911  Insulin secretion
caty04912  GnRH signaling pathway
caty04921  Oxytocin signaling pathway
caty04924  Renin secretion
caty04925  Aldosterone synthesis and secretion
caty04927  Cortisol synthesis and secretion
caty04929  GnRH secretion
caty04930  Type II diabetes mellitus
caty04934  Cushing syndrome
caty04935  Growth hormone synthesis, secretion and action
caty04973  Carbohydrate digestion and absorption
caty05010  Alzheimer disease
caty05020  Prion disease
caty05022  Pathways of neurodegeneration - multiple diseases
caty05031  Amphetamine addiction
caty05207  Chemical carcinogenesis - receptor activation
caty05410  Hypertrophic cardiomyopathy
caty05412  Arrhythmogenic right ventricular cardiomyopathy
caty05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:caty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105585586 (CACNA1D)
   04020 Calcium signaling pathway
    105585586 (CACNA1D)
   04024 cAMP signaling pathway
    105585586 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    105585586 (CACNA1D)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105585586 (CACNA1D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105585586 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105585586 (CACNA1D)
   04929 GnRH secretion
    105585586 (CACNA1D)
   04912 GnRH signaling pathway
    105585586 (CACNA1D)
   04921 Oxytocin signaling pathway
    105585586 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    105585586 (CACNA1D)
   04924 Renin secretion
    105585586 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    105585586 (CACNA1D)
   04927 Cortisol synthesis and secretion
    105585586 (CACNA1D)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    105585586 (CACNA1D)
   04261 Adrenergic signaling in cardiomyocytes
    105585586 (CACNA1D)
   04270 Vascular smooth muscle contraction
    105585586 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105585586 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    105585586 (CACNA1D)
   04727 GABAergic synapse
    105585586 (CACNA1D)
   04725 Cholinergic synapse
    105585586 (CACNA1D)
   04728 Dopaminergic synapse
    105585586 (CACNA1D)
   04726 Serotonergic synapse
    105585586 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    105585586 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105585586 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    105585586 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105585586 (CACNA1D)
   05020 Prion disease
    105585586 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    105585586 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    105585586 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    105585586 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    105585586 (CACNA1D)
   05414 Dilated cardiomyopathy
    105585586 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105585586 (CACNA1D)
   04934 Cushing syndrome
    105585586 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:caty04040]
    105585586 (CACNA1D)
Ion channels [BR:caty04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   105585586 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 105585586
NCBI-ProteinID: XP_011914888
Ensembl: ENSCATG00000028909
LinkDB
Position
Unknown
AA seq 2209 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVS
GEGETRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQMANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHVFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGP
IYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADHYFTDAWNTF
DALIVVGSVVDIAITEVNPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSR
GEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTF
PQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCA
FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRI
QPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEE
LRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYP
AKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEDDVFKRNGALLGNHVNH
VNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPT
STNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIR
SDSGDEQLPTICREDPEIHGYFRDPRCFGEQEYFSSEECYEDDSSPTWSRQNYGYYSRYP
GRNVDFERPRGYHHPQGFLEDDDSPICYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQS
SQEEVPSSPTFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRD
WTPCYTPLIQVEQSEALDQMNGSLPSLHRSSWYTDEPDISYRTFTPASLTVPSSFRNKNS
DKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVC
PRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq 6630 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagacttcctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaagtctggaggctttgatgtcaaagccctccgt
gcctttcgagtgttgcgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagctccatgtgcgttctca
gggaacggacgccagtgtactgccaatggcacggaatgtaggagtggctgggtcggcccg
aacggaggcatcaccaactttgataactttgcctttgctatgctcactgtgtttcagtgc
atcaccatggagggctggacagatgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctcatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagagagaaggcaaaagcacgggga
gatttccagaagctccgggagaagcagcagctggaggaggatctaaagggctacttggat
tggatcacccaagctgaggacatcgatcccgagaacgaggaagaaggaggagaggaaggc
aaacgaaatactagcatgcccaccagtgagactgagtctgtgaacacagagaacgtcagc
ggcgaaggcgagacccgaggctgctgtggaagtctctggtgctggtggagacggagaggc
gcggccaaggcggggccctctgggtgtcggcggtggggtcaagccatctcaaaatccaaa
ctcagccgacgctggcgtcgctggaaccgattcaatcgcagaagatgtagggccgccgtg
aagtctgtcacgttttactggctggttatcgtcctggtgtttctgaacaccttaaccatt
tcctctgagcactacaatcaaccggattggttgacacagattcaagatattgccaacaaa
gtcctcttggctctgtttacctgcgagatgctggtaaaaatgtacagcttgggtctccaa
gcatatttcgtctctcttttcaaccggtttgattgcttcgtggtgtgtggtggaatcact
gagacgatcttggtggaactggaaatcatgtctcccctggggatctctgtgtttcggtgt
gtgcgcctcttaagaatcttcaaagtgaccaggcactggacttctctgagcaacttagtg
gcatcgttgttaaactccatgaagtccatcgcttcgctgttacttctgctttttctcttc
attatcatcttttccttgcttgggatgcagctgtttggcggcaagtttaattttgatgaa
acgcaaaccaagcggagcacctttgacaatttccctcaagcacttctcacagtgttccag
atcctgacaggcgaagactggaacgctgtgatgtacgatggcatcatggcttacgggggc
ccgtcctcttcaggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaat
tatattctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagt
ttgaacactgctcagaaagaagaagcagaagaaaaggagaggaaaaagattgccagaaaa
gagagcctagaaaataaaaagaacaacaaaccagaagtcaaccagatggccaacagtgac
aacaaggttacaatcgatgactatagagaagaggatgaagacaaggacccctacccacct
tgcgatgtgccagtaggggaagaggaagaggaagaggaggaggatgaacctgaggttcct
gccggaccccgtcctcgaaggatctcggagttgaacatgaaggaaaaaattgcccccatc
cctgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacgtcttcaccaacctcatcctcgtcttcatcatgctgagcagc
gccgctctggccgcagaggaccccatccgcagccactccttccggaacacgatactgggt
tactttgactatgccttcacagccatctttactgttgagattctgctgaagatgacaact
tttggagctttcctccacaaaggggccttctgcaggaactacttcaatttgctggatatg
ctcgtggttggggtgtctctggtgtcatttgggattcaatccagtgccatctctgttgtg
aagattctgagagtcttaagggtcctgaggcccctcagggccatcaacagagcaaaagga
cttaagcacgtggtccagtgcgtcttcgtggccatccggaccatcggcaacatcatgatc
gtcaccaccctcctccagttcatgtttgcctgtattggggtccagttgttcaaggggaag
ttctatcgctgtacggatgaagccaaaagtaaccctgaagaatgcaggggacttttcatc
ctctacaaggatggggatgttgacagtcctgtggtccgtgagcggatctggcaaaacagt
gatttcaacttcgacaacgtcctctctgctatgatggcactcttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactcgaatggagagaacatcggccca
atctacaaccaccgcgtggagatttccatcttcttcatcatctacatcatcattgtagct
ttcttcatgatgaacatctttgtgggctttgtcatcgttacatttcaggagcaaggagaa
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcctttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgttcaatgacgccatggacatcctg
aacatggtcttcaccggggtgttcaccgtcgagatggttttgaaagtcatcgcctttaag
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagcagaccactatttcactgatgcatggaacactttt
gatgccttaattgttgttggtagcgtcgttgatattgctataactgaagtgaatccaact
gaaagtgaaaatgtccctgtcccaactgctacacctgggaactctgaagagagcaataga
atctccatcacctttttccgtcttttccgagtgatgcgattggtgaagcttctcagcagg
ggggaaggcatccggacattgctgtggacttttattaagtcctttcaggcactcccgtat
gtggccctcctcatagccatgctgttcttcatctatgcggtcattggcatgcagatgttt
gggaaagttgccatgagagataacaaccagatcaataggaacaataacttccagacgttt
ccccaggcggtgctgctgctcttcaggtgtgcgacaggtgaggcctggcaggagatcatg
ctggcctgcctcccagggaagctctgtgaccctgagtcagattacaaccccggggaggag
tatacatgtgggagcaactttgccattgtctatttcatcagtttttacatgctctgtgcg
tttctgatcatcaatctgtttgtggctgtcatcatggataatttcgactatctgacccgg
gactggtctattttggggcctcaccatttagatgaattcaaaagaatatggtcagaatat
gaccctgaggcaaagggaaggataaaacaccttgacgtggtcactctgcttcgacgcatc
cagcctcccctggggtttgggaagttatgcccacacagagtagcgtgcaagagattagtt
gccatgaacatgcctctcaacagtgacgggacagtcatgtttaatgcaaccctatttgct
ttggttcgaacagctcttaagatcaagaccgaagggaacctggagcaagctaatgaagaa
cttcgggctgtgataaagaagatttggaagaaaaccagcatgaaattacttgaccaagtt
gtccctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgata
caggactactttaggaaattcaagaaacggaaagaacaaggactggtgggaaagtaccct
gcgaagaacaccacaattgccctacaggcgggattaaggacactgcatgacattgggcca
gaaatccggcgtgctatatcgtgtgatttgcaagatgacgagcctgaggaaacaaaacga
gaagaagaagatgatgtgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcat
gttaatagtgataggagagattcccttcagcagaccaataccacccaccgtcccctgcat
gtccaaaggccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagca
ggaaattcggtgtgtcataaccatcataaccataattccataggaaagcaagttcccacc
tcaacaaatgccaatctcaataatgccaatatgtccaaagctgcccatggaaagcggccc
agcattgggaaccttgagcatgtgtctgaaaatgggcatcattcttcccacaagcatgac
cgggagcctcagagaaggtccagtgtgaaaagaacccgctattatgaaacttacattagg
tccgactcaggagatgaacagctcccaactatttgccgggaagacccagagatacatggc
tatttcagggacccccgctgcttcggggagcaggagtatttcagtagcgaggagtgctat
gaggatgacagctcgcccacctggagcaggcaaaactatggctactacagcagataccca
ggcagaaacgtggactttgagaggccccgaggctaccatcacccccaaggattcttggag
gacgatgactcgcccatttgctatgattcacggagatctccaaggagacgcctactacct
cccaccccagcatcccaccgcagatcctccttcaacttcgagtgcctgcgccggcagagc
agccaggaggaggtcccttcatctcccaccttcccccaccgcacggccctgcctctgcat
ctcatgcagcaacagatcatggcagttgctggcctagattcaagtaaagcccagaagtac
tcaccgagtcactcgacccggtcatgggccacccctccagcaacccctccctaccgggac
tggacaccgtgctacacccccctgatccaagtggagcagtcagaggccctggaccagatg
aacggcagcctgccgtccctgcaccgcagttcctggtacacagacgagcccgacatctcc
taccggactttcacaccagccagcctgaccgtccccagcagcttccggaacaaaaacagc
gacaagcagaggagcgcggacagcttggtggaggcagtcctgatatctgaaggcttggga
cgctatgcaagggacccaaaatttgtgtcagcaacaaaacatgaaatcgctgatgcctgt
gacctcaccatcgacgagatggagagtgcagccagcaccctgcttaatgggaacgtgtgt
ccccgagccaacggggatgtgggccccctctcacaccggcaggactatgagctacaggac
tttggtcctggctacagcgacgaagagccagaccctgggagggatgaggaggacctggcg
gatgaaatgatatgcatcaccaccttgtag

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