Cercocebus atys (sooty mangabey): 105586728 Help Entry 105586728         CDS       T07242                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism caty  Cercocebus atys (sooty mangabey) Pathway caty01521   EGFR tyrosine kinase inhibitor resistance caty01522   Endocrine resistance caty04010   MAPK signaling pathway caty04012   ErbB signaling pathway caty04014   Ras signaling pathway caty04062   Chemokine signaling pathway caty04068   FoxO signaling pathway caty04072   Phospholipase D signaling pathway caty04150   mTOR signaling pathway caty04151   PI3K-Akt signaling pathway caty04510   Focal adhesion caty04540   Gap junction caty04630   JAK-STAT signaling pathway caty04650   Natural killer cell mediated cytotoxicity caty04660   T cell receptor signaling pathway caty04662   B cell receptor signaling pathway caty04664   Fc epsilon RI signaling pathway caty04714   Thermogenesis caty04722   Neurotrophin signaling pathway caty04810   Regulation of actin cytoskeleton caty04910   Insulin signaling pathway caty04912   GnRH signaling pathway caty04915   Estrogen signaling pathway caty04917   Prolactin signaling pathway caty04926   Relaxin signaling pathway caty04935   Growth hormone synthesis, secretion and action caty05034   Alcoholism caty05160   Hepatitis C caty05161   Hepatitis B caty05163   Human cytomegalovirus infection caty05165   Human papillomavirus infection caty05200   Pathways in cancer caty05205   Proteoglycans in cancer caty05206   MicroRNAs in cancer caty05207   Chemical carcinogenesis - receptor activation caty05208   Chemical carcinogenesis - reactive oxygen species caty05210   Colorectal cancer caty05211   Renal cell carcinoma caty05213   Endometrial cancer caty05214   Glioma caty05215   Prostate cancer caty05220   Chronic myeloid leukemia caty05221   Acute myeloid leukemia caty05223   Non-small cell lung cancer caty05224   Breast cancer caty05225   Hepatocellular carcinoma caty05226   Gastric cancer caty05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:caty00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105586728 (SOS2)    04012 ErbB signaling pathway     105586728 (SOS2)    04014 Ras signaling pathway     105586728 (SOS2)    04630 JAK-STAT signaling pathway     105586728 (SOS2)    04068 FoxO signaling pathway     105586728 (SOS2)    04072 Phospholipase D signaling pathway     105586728 (SOS2)    04151 PI3K-Akt signaling pathway     105586728 (SOS2)    04150 mTOR signaling pathway     105586728 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105586728 (SOS2)    04540 Gap junction     105586728 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105586728 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105586728 (SOS2)    04660 T cell receptor signaling pathway     105586728 (SOS2)    04662 B cell receptor signaling pathway     105586728 (SOS2)    04664 Fc epsilon RI signaling pathway     105586728 (SOS2)    04062 Chemokine signaling pathway     105586728 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     105586728 (SOS2)    04912 GnRH signaling pathway     105586728 (SOS2)    04915 Estrogen signaling pathway     105586728 (SOS2)    04917 Prolactin signaling pathway     105586728 (SOS2)    04926 Relaxin signaling pathway     105586728 (SOS2)    04935 Growth hormone synthesis, secretion and action     105586728 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     105586728 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     105586728 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105586728 (SOS2)    05206 MicroRNAs in cancer     105586728 (SOS2)    05205 Proteoglycans in cancer     105586728 (SOS2)    05207 Chemical carcinogenesis - receptor activation     105586728 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     105586728 (SOS2)    05231 Choline metabolism in cancer     105586728 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     105586728 (SOS2)    05225 Hepatocellular carcinoma     105586728 (SOS2)    05226 Gastric cancer     105586728 (SOS2)    05214 Glioma     105586728 (SOS2)    05221 Acute myeloid leukemia     105586728 (SOS2)    05220 Chronic myeloid leukemia     105586728 (SOS2)    05211 Renal cell carcinoma     105586728 (SOS2)    05215 Prostate cancer     105586728 (SOS2)    05213 Endometrial cancer     105586728 (SOS2)    05224 Breast cancer     105586728 (SOS2)    05223 Non-small cell lung cancer     105586728 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     105586728 (SOS2)    05160 Hepatitis C     105586728 (SOS2)    05163 Human cytomegalovirus infection     105586728 (SOS2)    05165 Human papillomavirus infection     105586728 (SOS2)   09165 Substance dependence    05034 Alcoholism     105586728 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105586728 (SOS2)    01522 Endocrine resistance     105586728 (SOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH DUF5055 IQ_SEC7_PH Motif Other DBs NCBI-GeneID:  105586728 NCBI-ProteinID:  XP_011917436 Ensembl:  ENSCATG00000042288 LinkDB All DBs Position Unknown AA seq 1295 aa AA seqDB search MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPEFNEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKHPRR PGDPVCPFYSHQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHER HIFLFDGLMISCKPNHGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSK DENSVVFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVV KDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQE LLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEH HFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPP AIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSP NLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRVIEILQVFQDLNNFNGVLEIVSAVN SVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILK TEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGN ASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPT PLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSI FAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPP RQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPP PLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQN SSPHLPKLPPKTYKRELSHPPLYRLPLLENAETPQ NT seq 3888 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccttacgagttcttcagtgaggagaatagtccgaaatggcgg ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaaagaaga aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtgttagggtac aaagtggactaccatgtgtccctatatattgtggctgtactagaatatatctcagctgat attttaaaattggctggtaattacgtttttaatatccggcattatgaaatatctcagcag gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgat ataggcttggtttctctctgtgaagatgaacctagttcttccggtgaattaaactactat gatcttgtcagaactgaaatcgcagaagaaagacagtatctacgggaattaaatatgatc ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatt gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg attgaagacacagttgaaatgactgatgaaagtagtcctcatcccttagctggcagctgt tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt ctttcaccagagtttaatgaacatttcaataaattgatggccagacctgcagttgctcta cactttcagtctattgctgatggctttaaagaggcagttcgttatgtccttccacgtctt atgctggtgccagtgtatcactgttggcactattttgagttactaaagcacccccgccga cctggagatcctgtttgccctttttatagtcaccaattaagaagcaaacacctggctatc aaaaaaatgaatgaaattcagaaaaatatcgatggatgggaaggcaaagatattggacag tgttgtaatgaattcattatggagggaccattgacaagaatcggtgccaaacacgaacgg catatttttctgtttgatggcttaatgatcagttgtaaacctaatcatggccagactcgg cttccaggttacagtagtgcagaatacaggttaaaagaaaaatttgtcatgaggaaaata caaatttgtgataaagaagatacttgtgagtgcaagcatgcttttgaattagtatccaaa gatgagaacagcgtagtatttgctgctaagtctgctgaagaaaaaaacaactggatggca gcccttatttctcttcattatcgtagtactctagatcgaatgttagattcagtattactg aaagaagaaaatgagcaaccactgagattaccaagtcctgaagtatatcgttttgtagta aaagactctgaggaaaacattgtttttgaagacaacttgcaaagtagaagtggcatcccc attattaaaggaggaactgtagtgaagttaattgaaaggttaacatatcatatgtatgca gatcccaattttgttcgtacttttcttaccacatatcgttcattttgtaaaccacaggaa ttgctgagcttactgattgaacggtttgaaatcccagagccagaacctactgacgcagac aaattggcaatagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaag gaatacgtccaaccagtacaacttaggatcttaaatgtatttcggcattgggttgaacat catttttatgactttgaaagagatttggaattgcttgaaagactagaatccttcatttca agtgtaagagggaaagctatgaagaaatgggtagagtcaatcgctaagatcatcaagagg aagaagcaagctcaggcaaatggaataagccataatattacctttgaaagtccacctcca gccattgaatggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacactt catccaatagaaattgcacgtcagctgacacttttggagtctgatctctacaggaaagtt caaccatctgaacttgtaggaagtgtgtggaccaaagaagataaagaaataaattctcca aatttattaaaaatgattcgccataccacaaatctcaccctctggtttgaaaaatgcatt gtggaagcagaaaattttgaagaacgggttgcagtactaagtagagttatagaaattctg caagtttttcaagatttgaataatttcaatggcgtattggagatagtcagtgcagtaaat tcagtgtcagtatacagactagaccatacctttgaggcactgcaggaaagaaaaaggaaa attttggatgaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaactt aagtcaatcaatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaag actgaagaagggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagt aagaggaggaaagtagctgaaattactggagaaattcagcagtatcagaatcagccttac tgtttacggatagaaccagatatgaggagattctttgaaaaccttaaccccatgggaaat gcgtctgaaaaagagtttacagattatttgttcaacaagtcactagaaattgaacctcga aactgcaaacagccacctcgatttcctagaaaatcaactttctccttgaaatctcctgga ataaggcctaacacaggccgacatggctctacctcaggtactttacgaggtcacccaaca ccattagaaagagaaccatgtaaaataagctttagtcggattgctgaaactgagctggaa tcaacggtgtcagcaccaacttctccaaatacaccatctactccaccagtatctgcttct tcagaccttagtgtatttttagatgtggatctcaacagctcctgtggcagcaatagcatc tttgctccagtgcttttgccacattcaaagtctttctttagttcatgtggtagtttacat aaactaagtgaagagcccctgattcctcctcctcttcctcctcgaaaaaagtttgatcat gatgcttcaaattctaagggaaatatgaaatctgatgatgatcctcctgctattccaccg agacagcctcctcctcccaaggtaaaacccagagttcctgttcctactggtgcatttgat gggcctctgcatagtccacctccaccaccaccaagagatcctcttcctgatacccctcca ccggttccccttcggcctccagaacactttataaactgtccatttaatcttcagccacct ccactggggcatcttcacagagattcagactggctcagagacattagtacgtgtccaaat tcgccaagcactcctcctagcacaccctctccaagggtaccacgtcgatgctatgtgctc agttctagtcagaataatcttgctcatcctccagctccccctgttccaccaaggcagaat tcaagccctcatctgccaaaactgccaccaaagacttacaaacgggagctttcgcatccc ccattgtacagactgcctttgctagaaaatgcagaaactccccaatga

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