KEGG   Cercocebus atys (sooty mangabey): 105590377
Entry
105590377         CDS       T07242                                 
Symbol
GSTA4
Name
(RefSeq) glutathione S-transferase A4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty00480  Glutathione metabolism
caty00980  Metabolism of xenobiotics by cytochrome P450
caty00982  Drug metabolism - cytochrome P450
caty00983  Drug metabolism - other enzymes
caty01100  Metabolic pathways
caty01524  Platinum drug resistance
caty05200  Pathways in cancer
caty05204  Chemical carcinogenesis - DNA adducts
caty05207  Chemical carcinogenesis - receptor activation
caty05208  Chemical carcinogenesis - reactive oxygen species
caty05225  Hepatocellular carcinoma
caty05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:caty00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    105590377 (GSTA4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    105590377 (GSTA4)
   00982 Drug metabolism - cytochrome P450
    105590377 (GSTA4)
   00983 Drug metabolism - other enzymes
    105590377 (GSTA4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105590377 (GSTA4)
   05204 Chemical carcinogenesis - DNA adducts
    105590377 (GSTA4)
   05207 Chemical carcinogenesis - receptor activation
    105590377 (GSTA4)
   05208 Chemical carcinogenesis - reactive oxygen species
    105590377 (GSTA4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    105590377 (GSTA4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    105590377 (GSTA4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    105590377 (GSTA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:caty02000]
    105590377 (GSTA4)
Enzymes [BR:caty01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     105590377 (GSTA4)
Transporters [BR:caty02000]
 Other transporters
  Pores ion channels [TC:1]
   105590377 (GSTA4)
SSDB
Motif
Pfam: GST_C_3 GST_N GST_C GST_C_2 GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 105590377
NCBI-ProteinID: XP_011925274
Ensembl: ENSCATG00000027052
UniProt: A0A2K5L7J5
LinkDB
Position
Unknown
AA seq 222 aa
MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLHKLQDGNHLLFQQVPMVEI
DGMKLVQTRSILHYIADKHNLFGKDLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
VVNMAQKAIIRYFPVFEKILRGHGQNFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFKP
NT seq 669 nt   +upstreamnt  +downstreamnt
atggcagcaaggcccaagctccactatcccaacggaagaggccggatggagtccgtgaga
tgggttttagccgccgccggagtcgagtttgatgaagaatttctggaaacaaaagaacag
ttacacaagttgcaggatggtaaccacctgctgttccaacaagtgcctatggttgaaatt
gacgggatgaagttggtacagacccgaagcattctccactacatagcagacaagcacaat
ctctttggcaaggacctcaaggagagaaccctgattgacatgtatgtggaggggacgctg
gatctgctggaactgcttatcatgcatcctttcttaaaaccagatgatcaacaaaaggaa
gtggttaacatggcccagaaggctataattagatactttcctgtgtttgaaaagatttta
aggggtcacggacaaaactttcttgttggtaatcagctgagccttgcagatgtgatttta
ctccaaaccattttagctctagaagagaaaattcctaatatcctgtctgcatttcctttc
ctccaggagtacacagtgaaactaagtaatatccctacaattaagagattccttgaacct
ggcagcaagaagaagcctccccctgatgaaatttatgtgagaaccgtctacaacatcttt
aagccgtaa

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