Cercocebus atys (sooty mangabey): 105590750
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Entry
105590750 CDS
T07242
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty04140
Autophagy - animal
caty04141
Protein processing in endoplasmic reticulum
caty04210
Apoptosis
caty04932
Non-alcoholic fatty liver disease
caty05010
Alzheimer disease
caty05012
Parkinson disease
caty05014
Amyotrophic lateral sclerosis
caty05016
Huntington disease
caty05017
Spinocerebellar ataxia
caty05022
Pathways of neurodegeneration - multiple diseases
caty05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
105590750 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105590750 (ERN1)
09143 Cell growth and death
04210 Apoptosis
105590750 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105590750 (ERN1)
05012 Parkinson disease
105590750 (ERN1)
05014 Amyotrophic lateral sclerosis
105590750 (ERN1)
05016 Huntington disease
105590750 (ERN1)
05017 Spinocerebellar ataxia
105590750 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
105590750 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105590750 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105590750 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
caty01001
]
105590750 (ERN1)
Enzymes [BR:
caty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105590750 (ERN1)
Protein kinases [BR:
caty01001
]
Serine/threonine kinases: Other
IRE family
105590750 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
CytochromB561_N
Motif
Other DBs
NCBI-GeneID:
105590750
NCBI-ProteinID:
XP_011926014
Ensembl:
ENSCATG00000040819
UniProt:
A0A2K5NET2
LinkDB
All DBs
Position
Unknown
AA seq
977 aa
AA seq
DB search
MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTELKFDTGLKSKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSR
DVEEKPAHAPARPEAPVDSMLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQ
KELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLCSG
SSASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAA
GRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQ
RQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPAEVRETLGSLPDDFVSYFTSRFPHLLAHTYRAMELCSHERLFQPY
YFHRPPEPQPPVTPDAL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgacgctgctgctgcccggcctcgggattttt
ggaagtaccagcacggtgacgcttcctgaaaccttgttgtttgtgtcaacgctggatgga
agtttacatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagatcca
gtcctgcaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaatgatggc
agcctgtatacgcttggaagcaagaataatgaaggcctgacgaaacttccttttaccatc
ccagaattggtgcaggcatccccgtgccgaagttcagatggaatcctctacatgggtaaa
aagcaggacatctggtatgttattgacctcctgactggggagaagcagcagaccttgtca
tcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaacagaa
tacaccatcaccatgtacgacaccaaaacgcgagagctccggtggaatgccacctacttt
gactacgcagcctcgctgcccgaggacgacatggactacaagatgtcccactttgtgtcc
aatggtgatgggctggtggtgaccgtggacagtgaatctggggatgtcctgtggatccaa
aactacgcctcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtg
atgcacatcaatgtcgccgtggagaccctgcgctatctgaccttcatgtctggggaggtg
gggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaagctg
acgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctcaatggta
cacgagggagttgctgtcgtgccccgcggcagcacacttcctttgctggaagggccccag
actgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcacagagctc
aagtttgacaccggactcaaaagcaagaacaagctcaactacttgaggaattactggctt
ctgataggccaccatgaaaccccactgtctgcatctaccaagatgctggagagatttccc
aacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagcttt
gaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtgtctcgg
gatgtggaggagaagcccgcccatgcccccgcccggcccgaggcccccgtggactccatg
ctcaaggacgtggccaccatcatcctgagcaccttcctgctgattggctgggtggccttc
atcatcacctaccccctgagcatgcatcagcaacagcagctccagcaccagcagttccag
aaggaactggagaagattcagctcctgcagcagcagcagcagcagctgcccttccaccca
cctggagacacggctcaggacggcgagcttctggacacatctggcccatactcagagagc
tcgggcaccagcagccccaacacgtcccccagggcttccaaccactcgctctgctctggc
agctctgcctccaaggctggcagcagcccctccctggagcaagacgacggagatgaggaa
accagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggccatgga
gctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtgaagagg
atcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaatcagat
gagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccagtacatt
gccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggactttgcgcat
ctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccaccttcac
tccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatgcccaat
gcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctggcagcg
ggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggattgctcca
gagatgctgagcgaagactgtaaggagaaccctacctacacagtggacatcttttctgca
ggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtccctgcag
cggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagagaagcac
gaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcagaaacgc
ccctcagcgaagcacgtgctgaaacacccgttcttctggagcctagagaagcagctccag
ttcttccaggacgtgagcgacagaatagaaaaggaatccctggatggcccgattgtgaag
cagttagagagaggcgggagagccgtggtgaagatggactggcgagagaacatcaccgtc
cccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcagagatctc
ctccgagccatgagaaataagaagcaccactaccgggaactgcctgcggaggtgcgggag
acgctggggtccctccctgacgacttcgtgtcctacttcacgtctcgcttcccccacctc
ctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccagccctac
tacttccacaggcccccagagccccagcccccagtgactccagacgccctctga
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