KEGG   Cercocebus atys (sooty mangabey): 105592813
Entry
105592813         CDS       T07242                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty03420  Nucleotide excision repair
caty04115  p53 signaling pathway
caty04120  Ubiquitin mediated proteolysis
caty05161  Hepatitis B
caty05169  Epstein-Barr virus infection
caty05200  Pathways in cancer
caty05202  Transcriptional misregulation in cancer
caty05210  Colorectal cancer
caty05212  Pancreatic cancer
caty05213  Endometrial cancer
caty05214  Glioma
caty05216  Thyroid cancer
caty05217  Basal cell carcinoma
caty05218  Melanoma
caty05220  Chronic myeloid leukemia
caty05222  Small cell lung cancer
caty05223  Non-small cell lung cancer
caty05224  Breast cancer
caty05225  Hepatocellular carcinoma
caty05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:caty00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    105592813 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    105592813 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    105592813 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105592813 (DDB2)
   05202 Transcriptional misregulation in cancer
    105592813 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105592813 (DDB2)
   05212 Pancreatic cancer
    105592813 (DDB2)
   05225 Hepatocellular carcinoma
    105592813 (DDB2)
   05226 Gastric cancer
    105592813 (DDB2)
   05214 Glioma
    105592813 (DDB2)
   05216 Thyroid cancer
    105592813 (DDB2)
   05220 Chronic myeloid leukemia
    105592813 (DDB2)
   05217 Basal cell carcinoma
    105592813 (DDB2)
   05218 Melanoma
    105592813 (DDB2)
   05213 Endometrial cancer
    105592813 (DDB2)
   05224 Breast cancer
    105592813 (DDB2)
   05222 Small cell lung cancer
    105592813 (DDB2)
   05223 Non-small cell lung cancer
    105592813 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105592813 (DDB2)
   05169 Epstein-Barr virus infection
    105592813 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:caty04121]
    105592813 (DDB2)
   03400 DNA repair and recombination proteins [BR:caty03400]
    105592813 (DDB2)
Ubiquitin system [BR:caty04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     105592813 (DDB2)
DNA repair and recombination proteins [BR:caty03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      105592813 (DDB2)
SSDB
Motif
Pfam: WD40 WD40_CDC20-Fz WD40_Prp19 WD40_WDHD1_1st Beta-prop_WDR75_1st Beta-prop_EML_2 WDR55 Beta-prop_WDR90_POC16_2nd Beta-prop_RIG_2nd Beta-prop_EIPR1 Beta-prop_IFT140_1st EIF3I Beta-prop_TEP1_2nd Beta-prop_WDR19_1st Beta-prop_CAF1B_HIR1 Beta-prop_HPS5 Beta-prop_TEP1_C WD40_MABP1-WDR62_2nd NBCH_WD40 WD40_RFWD3 Beta-prop_EML Beta-prop_Vps41 WD_LRWD1
Other DBs
NCBI-GeneID: 105592813
NCBI-ProteinID: XP_011930665
Ensembl: ENSCATG00000037043
UniProt: A0A2K5MQ03
LinkDB
Position
Unknown
AA seq 427 aa
MAPKKRPETQKTSEIVLRPRNKRSRSPRELEPEAKKLCAKGSGPSRRGDSDCLWAGLAGP
QILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWH
PTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGT
TRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRM
HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSPDG
ARLLTTDQKSEIRIYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPN
FKSCTPYEMRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQ
EEARTRK
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggctcccaagaaacgcccagaaacccagaagacctccgagattgtattacgccccagg
aacaagaggagcaggagtccccgggagctggagcccgaggccaagaagctctgtgcgaag
ggctccggtcctagcagaagaggtgactcagactgcctctgggcggggctggctggccca
cagatcctgccgccatgccgcagcatcgtcaggaccctccaccagcataagctgggcaga
gcttcctggccatctgtccagcaggggctccagcagtcctttttgcacactctggattct
taccggatattacaaaaggctgccccctttgacaggagggctacgtccttggcgtggcac
ccgactcaccccagcactgtggctgtgggttccaaagggggagatatcatgctctggaat
tttggcatcaaggacaaacccaccttcatcaaagggattggagctggagggagcatcact
gggctgaagtttaaccctctcaataccaaccagttttacgcctcctcaatggagggaaca
actaggctgcaagactttaaaggcaacattctacgagtttttgccagctcagacaccatc
aacatctggttttgtagcctggatgtgtccgccagtagccgaatggtggtcacaggagac
aacgtggggaacgtgatcctgctgaacatggacggcaaagagctttggaatctcagaatg
cacaaaaagaaagtgacgcatgtggccctgaacccatgctgtgattggttcctggccaca
gcctccgtagatcaaacagtgaaaatctgggacctgcgccaggttagagggaaagccagc
ttcctctactcgctgccgcacaggcatcctgtcaacgcagcttgtttcagtcccgatgga
gcccggctcctgaccacggaccagaagagcgagatccgaatttactctgcttcccagtgg
gactgccccctgggcctgatcccgcaccctcaccgtcacttccagcacctcacacccatc
aaggcagcctggcatcctcgctacaacctcattgtcgtaggccgatacccagatcctaat
ttcaaaagttgtaccccctatgaaatgaggacgatcgatgtgtttgatggaaactcaggg
aagatgatgtgtcagctctatgacccagaatcttctggcatcagttcgctcaatgagttc
aatcccatgggggacacgctggcctctgcaatgggttaccacattctcatctggagccag
gaggaagccaggacccggaaatga

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