Cercocebus atys (sooty mangabey): 105594004
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Entry
105594004 CDS
T07242
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty01521
EGFR tyrosine kinase inhibitor resistance
caty01522
Endocrine resistance
caty04010
MAPK signaling pathway
caty04014
Ras signaling pathway
caty04015
Rap1 signaling pathway
caty04066
HIF-1 signaling pathway
caty04068
FoxO signaling pathway
caty04081
Hormone signaling
caty04114
Oocyte meiosis
caty04140
Autophagy - animal
caty04144
Endocytosis
caty04150
mTOR signaling pathway
caty04151
PI3K-Akt signaling pathway
caty04152
AMPK signaling pathway
caty04211
Longevity regulating pathway
caty04213
Longevity regulating pathway - multiple species
caty04510
Focal adhesion
caty04520
Adherens junction
caty04550
Signaling pathways regulating pluripotency of stem cells
caty04730
Long-term depression
caty04913
Ovarian steroidogenesis
caty04914
Progesterone-mediated oocyte maturation
caty05200
Pathways in cancer
caty05202
Transcriptional misregulation in cancer
caty05205
Proteoglycans in cancer
caty05214
Glioma
caty05215
Prostate cancer
caty05218
Melanoma
caty05224
Breast cancer
caty05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105594004 (IGF1R)
04014 Ras signaling pathway
105594004 (IGF1R)
04015 Rap1 signaling pathway
105594004 (IGF1R)
04066 HIF-1 signaling pathway
105594004 (IGF1R)
04068 FoxO signaling pathway
105594004 (IGF1R)
04151 PI3K-Akt signaling pathway
105594004 (IGF1R)
04152 AMPK signaling pathway
105594004 (IGF1R)
04150 mTOR signaling pathway
105594004 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
105594004 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105594004 (IGF1R)
04140 Autophagy - animal
105594004 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
105594004 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105594004 (IGF1R)
04520 Adherens junction
105594004 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
105594004 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
105594004 (IGF1R)
04914 Progesterone-mediated oocyte maturation
105594004 (IGF1R)
09156 Nervous system
04730 Long-term depression
105594004 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
105594004 (IGF1R)
04213 Longevity regulating pathway - multiple species
105594004 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105594004 (IGF1R)
05202 Transcriptional misregulation in cancer
105594004 (IGF1R)
05205 Proteoglycans in cancer
105594004 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105594004 (IGF1R)
05214 Glioma
105594004 (IGF1R)
05218 Melanoma
105594004 (IGF1R)
05215 Prostate cancer
105594004 (IGF1R)
05224 Breast cancer
105594004 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105594004 (IGF1R)
01522 Endocrine resistance
105594004 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
caty01001
]
105594004 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
caty04090
]
105594004 (IGF1R)
Enzymes [BR:
caty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105594004 (IGF1R)
Protein kinases [BR:
caty01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
105594004 (IGF1R)
CD molecules [BR:
caty04090
]
Proteins
105594004 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Furin-like
Pkinase
Recep_L_domain
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
105594004
NCBI-ProteinID:
XP_011933086
Ensembl:
ENSCATG00000027553
LinkDB
All DBs
Position
Unknown
AA seq
1246 aa
AA seq
DB search
MTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDL
CPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCSA
PDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDG
ECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLL
INIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFY
VLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRN
NGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQ
DACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEI
LYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHN
YCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKV
FENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDLEELETEYPFFESR
VDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWE
PRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNY
TARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK
RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGV
VKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMEL
MTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVV
LWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLE
IISSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHS
GHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
3741 nt
NT seq
+upstream
nt +downstream
nt
atgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggccatc
aggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatcctg
gatgcagtgtccaataactacattgtggggaataagcccccaaaggaatgcggggacctg
tgtccggggaccatggaggagaagccgatgtgcgagaagaccaccatcaacaatgagtac
aactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagtgcctgtgggaag
agggcatgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagcgcg
cctgacaacgacacggcctgtgtagcttgccgccactactactacgccggtgtctgcgtg
cctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgacttc
tgcgccaacatcctcagcgccgagagcagcgactccgagggtttcgtgatccacgatggc
gagtgcatgcaggagtgcccctcaggcttcatccgcaacggcagccagagcatgtactgc
atcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagaccatt
gattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttgctc
attaacatccgacgggggaataacattgcttcagaactggagaacttcatggggctcatc
gaggtggtgacgggctacgtgaagatccgccattcccatgccttggtctccttgtccttc
ctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttctac
gtcctcgacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgaccatc
aaagcagggaaaatgtactttgctttcaatcccaaattgtgtgtttcggaaatttaccgc
atggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccaggaac
aacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacgtgg
aagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctcatc
agcttcaccgtttactacaaggaagcaccttttaagaatgtcacggagtatgatgggcag
gatgcctgcggctccaacagctggaacatggtggacgtggacctcccgcccaacaaggac
gtggagcccggcatcttactgcatgggctgaagccctggactcagtacgccgtttacgtc
aaggctgtgaccctcaccatggtggagaacgaccatatccgtggggccaagagtgagatc
ttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagcatcg
aactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaacctg
agttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcacaat
tactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccattgacattgag
gaggtcacagagaacccgaagactgaggtgtgtggtggagagaaagggccttgctgcgcc
tgccccaaaactgaagcagagaagcaggccgagaaggaggaggctgagtaccgcaaagtc
tttgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcggagagat
gtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggcagcagac
acctacaacatcacagatctggaagagctagagacagagtaccctttctttgagagcaga
gtggataataaggagagaactgtcatttctaaccttcggcctttcacattgtaccgcatt
gatatccacagctgcaaccacgaggctgagaaactgggctgcagcgcctccaacttcgtc
tttgcaaggactatgcctgcagaaggagcagatgacattcctgggccagtgacctgggag
ccaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatggattg
attctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtgtcc
agacaggaatataggaagtatggaggggccaagctaaaccggctaaacccggggaactac
acagcccggattcaggctacatctctctctgggaatgggtcatggacagatcctgtgttc
ttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctgccc
gtcgctgtcctgttgatcgtgggagggttggtgatcatgctgtacgtcttccatagaaag
agaaataacagcaggctggggaatggagtgctgtacgcgtctgtgaacccggagtacttc
agcgctgcggatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcaccatg
agccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggtgtg
gtgaaagacgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcgagcatg
cgtgaaaggatcgagtttctcaacgaggcttctgtgatgaaggagttcaattgtcaccat
gtggtgcggttgctgggtgtggtgtcccagggccagccaacgctggtcatcatggaactg
atgacgcggggcgatctcaaaagttatctccggtctctgaggccagaaatggagaataat
ccagtcctagcacctccaagcctaagcaagatgattcagatggctggagagattgcagac
ggcatggcatacctcaacgccaacaagttcgtccacagagaccttgctgcccggaattgc
atggtagccgaggatttcacagtcaaaattggagattttgggatgacgcgagatatctat
gagacagactattaccggaaaggagggaaagggctattgcccgtgcgctggatgtctccc
gagtccctcaaggatggagtcttcaccacttactctgacgtctggtccttcggggttgtc
ctctgggagatcgccacactggccgagcagccctaccagggcttgtccaacgagcaagtc
cttcgcttcgtcatggagggcggccttctggacaagccagacaactgccccgacatgctg
tttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctggag
atcatcagcagcatcaaagacgagatggagcctggcttccgggaggtctccttctactac
agtgaggagaacaagctgcccgagccggaggagctggacctggagccagagaacatggag
agcgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacactca
ggacacaaggccgagaacggccccggccctggagtgctggtgctccgtgccagcttcgat
gagagacagccttacgcacacatgaacggtggccgcaagaacgagcgggccttgccgctg
ccccagtcttcgacctgctga
DBGET
integrated database retrieval system
