Cercocebus atys (sooty mangabey): 105595926 Help Entry 105595926         CDS       T07242                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism caty  Cercocebus atys (sooty mangabey) Pathway caty01521   EGFR tyrosine kinase inhibitor resistance caty04151   PI3K-Akt signaling pathway caty04217   Necroptosis caty04380   Osteoclast differentiation caty04550   Signaling pathways regulating pluripotency of stem cells caty04620   Toll-like receptor signaling pathway caty04621   NOD-like receptor signaling pathway caty04630   JAK-STAT signaling pathway caty04658   Th1 and Th2 cell differentiation caty04659   Th17 cell differentiation caty05140   Leishmaniasis caty05145   Toxoplasmosis caty05152   Tuberculosis caty05160   Hepatitis C caty05161   Hepatitis B caty05162   Measles caty05163   Human cytomegalovirus infection caty05164   Influenza A caty05165   Human papillomavirus infection caty05166   Human T-cell leukemia virus 1 infection caty05167   Kaposi sarcoma-associated herpesvirus infection caty05168   Herpes simplex virus 1 infection caty05169   Epstein-Barr virus infection caty05171   Coronavirus disease - COVID-19 caty05200   Pathways in cancer caty05203   Viral carcinogenesis caty05212   Pancreatic cancer caty05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:caty00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105595926 (JAK1)    04151 PI3K-Akt signaling pathway     105595926 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105595926 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105595926 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105595926 (JAK1)    04621 NOD-like receptor signaling pathway     105595926 (JAK1)    04658 Th1 and Th2 cell differentiation     105595926 (JAK1)    04659 Th17 cell differentiation     105595926 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     105595926 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105595926 (JAK1)    05203 Viral carcinogenesis     105595926 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105595926 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     105595926 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105595926 (JAK1)    05161 Hepatitis B     105595926 (JAK1)    05160 Hepatitis C     105595926 (JAK1)    05171 Coronavirus disease - COVID-19     105595926 (JAK1)    05164 Influenza A     105595926 (JAK1)    05162 Measles     105595926 (JAK1)    05168 Herpes simplex virus 1 infection     105595926 (JAK1)    05163 Human cytomegalovirus infection     105595926 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     105595926 (JAK1)    05169 Epstein-Barr virus infection     105595926 (JAK1)    05165 Human papillomavirus infection     105595926 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     105595926 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105595926 (JAK1)    05140 Leishmaniasis     105595926 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105595926 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:caty01001]     105595926 (JAK1) Enzymes [BR:caty01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105595926 (JAK1) Protein kinases [BR:caty01001]  Non-receptor tyrosine kinases   JAK family [OT]    105595926 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  105595926 NCBI-ProteinID:  XP_011937758 Ensembl:  ENSCATG00000041174 UniProt:  A0A2K5NH39 LinkDB All DBs Position Unknown AA seq 1154 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEVPEPGVEVIFYMSDREPLRLGSGEYTAEEL CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHSNDSGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEQGQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRIFKKDLVQGEHLGRGTRTHIYSG TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT SFQNLIEGFEALLK NT seq 3465 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaacctggaggtccctgagccaggggtggaagtgatcttc tatatgtcggacagggagcccctccggctgggcagtggagagtatacagcagaggaactg tgcatcagggctgcacaggcatgccgtatctctcctctttgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccaaatcgcaccatcaccgttgatgacaag atgtccctccgactccactaccggatgaggttctatttcaccaattggcacggaaccaac gacaatgagcagtcagtgtggcgtcattctccaaagaagcagaaaaatggctatgagaaa aaaaaggttccagatgcaacccctctccttgatgccagctcactggagtatctgtttgct cagggacagtatgatttggtgaaatgcctggctcccattcgagaccccaagaccgagcag gatgggcatgatattgaaaacgagtgtctggggatggctgtcctggccatctcacactat gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc gtgtccacgcatgacctgaaggtgaaatacttggctaccttggaaactttgacaaaacat tatggcgctgaaatatttgagacttccatgttgctgatttcatcagaaaatgagatgaat tggtttcattcgaatgacagtggaaatgttctgtactatgaagtgatggtgactgggaat cttggaatccagtggaggcataaaccaaatgttgtttctgttgaaaaggaaaaaaataaa ctgaagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaagatccgg gaagagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtct gtggtcagcattaacaagcaggacaacaagaaaatggaactgaagctctcttcccatgag gaggccttgtcctttgtgtcactggtagatggctacttccggctcaccgcagacgcccat cattacctctgcaccgacgtggcccccccgttgatcgtccacaacatacagaatggctgt catggtccaatctgtacagaatacgccatcaataaattgcggcaagaaggaagcgaggag gggatgtacgtgctgaggtggagctgcaccgactttgacaacatcctcatgaccgtcacc tgctttgagaagtctgagcaggggcagggtgcccagaagcagttcaagaacttccagatc gaggtgcagaagggccgctacagcctgcatggttcggaccgcagcttccccagcttggga gacctcatgagccacctcaagaagcagatcctgcgcacggataacatcagcttcatgttg aaacgctgctgccagcccaagccccgagaaatctccaacctgctggtggctactaagaaa gcccaggagtggcagcccgtctaccccatgagccagctgagttttgatcggatcttcaag aaggatctagtgcagggcgagcaccttgggagaggcacaagaacacacatctactctggg accctgatggattacaaggatgacgaaggaacttctgaagagaagaagataaaagtgatc ctcaaagtcttagaccccagccacagggatatttccctggccttcttcgaggcagccagc atgatgagacaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgcgac gtggagaatatcatggtggaagagtttgtggaagggggtcctctggatctcttcatgcac cggaaaagcgatgtccttactacaccctggaaattcaaagttgccaaacagctggccagt gccctgagctacttggaagataaagacctggtccatggaaatgtgtgtactaaaaacctc ctcctggcccgtgagggcatcgacagcgagtgtggtccgttcatcaagctcagtgaccct ggcatccccattacggtgctgtctaggcaagagtgcattgaacgaatcccatggattgct cccgagtgtgttgaggactccaagaacctgagtgtggctgctgacaagtggagctttgga actacgctctgggaaatctgctacaatggcgagatccccttgaaagacaagacactgatt gagaaagagagattctatgaaagccggtgcaggccagtgacaccatcatgtaaggagctg gctgacctcatgacccgctgcatgaactacgaccccaatcagaggcccttcttccgagcc atcatgagagacattaataagcttgaagagcagaatccagatattgtttcagaaaaaaag ccagcaactgaagtggaccccacgcattttgagaagcgcttcctaaagaggatccgtgac ttgggagagggccactttgggaaggttgagctctgcaggtatgaccccgaaggggacaat acaggggagcaggtggctgtcaaatctctgaagcctgagagtggaggtaaccacatagct gatctgaaaaaggaaatcgagatcttaaggaacctctatcatgagaacattgtgaagtac aaaggaatctgcacggaagacggaggaaatggtattaagctcatcatggaatttctgcct tcgggaagccttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcag ctaaaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatatgtt caccgtgacttggcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattgga gacttcggtttaaccaaagcaattgaaaccgataaggagtattacaccgtcaaggatgac cgggacagccctgtgttttggtatgctccagaatgtttaatgcaatctaaattttatatc gcctctgacgtctggtcttttggagtcactctgcatgagctgctgacttactgtgattca gattctagtcccatggctttgttcctgaaaatgataggcccaacccatggccagatgaca gtcacaagacttgtgaatacattaaaagaaggaaaacgcctgccgtgcccgcctaactgt ccagatgaggtttatcagcttatgaggaaatgctgggaattccaaccatccaatcggaca agctttcagaaccttattgaaggatttgaagcacttttaaaataa

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