Cercocebus atys (sooty mangabey): 105599331
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Entry
105599331 CDS
T07242
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha type isoform X1
KO
K02677
classical protein kinase C alpha type [EC:
2.7.11.13
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty01521
EGFR tyrosine kinase inhibitor resistance
caty04010
MAPK signaling pathway
caty04012
ErbB signaling pathway
caty04014
Ras signaling pathway
caty04015
Rap1 signaling pathway
caty04020
Calcium signaling pathway
caty04066
HIF-1 signaling pathway
caty04070
Phosphatidylinositol signaling system
caty04071
Sphingolipid signaling pathway
caty04072
Phospholipase D signaling pathway
caty04082
Neuroactive ligand signaling
caty04150
mTOR signaling pathway
caty04151
PI3K-Akt signaling pathway
caty04261
Adrenergic signaling in cardiomyocytes
caty04270
Vascular smooth muscle contraction
caty04310
Wnt signaling pathway
caty04360
Axon guidance
caty04370
VEGF signaling pathway
caty04510
Focal adhesion
caty04540
Gap junction
caty04613
Neutrophil extracellular trap formation
caty04650
Natural killer cell mediated cytotoxicity
caty04664
Fc epsilon RI signaling pathway
caty04666
Fc gamma R-mediated phagocytosis
caty04670
Leukocyte transendothelial migration
caty04713
Circadian entrainment
caty04720
Long-term potentiation
caty04723
Retrograde endocannabinoid signaling
caty04724
Glutamatergic synapse
caty04725
Cholinergic synapse
caty04726
Serotonergic synapse
caty04727
GABAergic synapse
caty04728
Dopaminergic synapse
caty04730
Long-term depression
caty04750
Inflammatory mediator regulation of TRP channels
caty04911
Insulin secretion
caty04912
GnRH signaling pathway
caty04916
Melanogenesis
caty04918
Thyroid hormone synthesis
caty04919
Thyroid hormone signaling pathway
caty04921
Oxytocin signaling pathway
caty04925
Aldosterone synthesis and secretion
caty04926
Relaxin signaling pathway
caty04928
Parathyroid hormone synthesis, secretion and action
caty04929
GnRH secretion
caty04933
AGE-RAGE signaling pathway in diabetic complications
caty04935
Growth hormone synthesis, secretion and action
caty04960
Aldosterone-regulated sodium reabsorption
caty04961
Endocrine and other factor-regulated calcium reabsorption
caty04970
Salivary secretion
caty04971
Gastric acid secretion
caty04972
Pancreatic secretion
caty05017
Spinocerebellar ataxia
caty05022
Pathways of neurodegeneration - multiple diseases
caty05031
Amphetamine addiction
caty05032
Morphine addiction
caty05143
African trypanosomiasis
caty05146
Amoebiasis
caty05161
Hepatitis B
caty05163
Human cytomegalovirus infection
caty05164
Influenza A
caty05170
Human immunodeficiency virus 1 infection
caty05171
Coronavirus disease - COVID-19
caty05200
Pathways in cancer
caty05205
Proteoglycans in cancer
caty05206
MicroRNAs in cancer
caty05207
Chemical carcinogenesis - receptor activation
caty05214
Glioma
caty05223
Non-small cell lung cancer
caty05225
Hepatocellular carcinoma
caty05231
Choline metabolism in cancer
caty05415
Diabetic cardiomyopathy
caty05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105599331 (PRKCA)
04012 ErbB signaling pathway
105599331 (PRKCA)
04014 Ras signaling pathway
105599331 (PRKCA)
04015 Rap1 signaling pathway
105599331 (PRKCA)
04310 Wnt signaling pathway
105599331 (PRKCA)
04370 VEGF signaling pathway
105599331 (PRKCA)
04066 HIF-1 signaling pathway
105599331 (PRKCA)
04020 Calcium signaling pathway
105599331 (PRKCA)
04070 Phosphatidylinositol signaling system
105599331 (PRKCA)
04072 Phospholipase D signaling pathway
105599331 (PRKCA)
04071 Sphingolipid signaling pathway
105599331 (PRKCA)
04151 PI3K-Akt signaling pathway
105599331 (PRKCA)
04150 mTOR signaling pathway
105599331 (PRKCA)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
105599331 (PRKCA)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
105599331 (PRKCA)
04540 Gap junction
105599331 (PRKCA)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
105599331 (PRKCA)
04650 Natural killer cell mediated cytotoxicity
105599331 (PRKCA)
04664 Fc epsilon RI signaling pathway
105599331 (PRKCA)
04666 Fc gamma R-mediated phagocytosis
105599331 (PRKCA)
04670 Leukocyte transendothelial migration
105599331 (PRKCA)
09152 Endocrine system
04911 Insulin secretion
105599331 (PRKCA)
04929 GnRH secretion
105599331 (PRKCA)
04912 GnRH signaling pathway
105599331 (PRKCA)
04921 Oxytocin signaling pathway
105599331 (PRKCA)
04926 Relaxin signaling pathway
105599331 (PRKCA)
04935 Growth hormone synthesis, secretion and action
105599331 (PRKCA)
04918 Thyroid hormone synthesis
105599331 (PRKCA)
04919 Thyroid hormone signaling pathway
105599331 (PRKCA)
04928 Parathyroid hormone synthesis, secretion and action
105599331 (PRKCA)
04916 Melanogenesis
105599331 (PRKCA)
04925 Aldosterone synthesis and secretion
105599331 (PRKCA)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
105599331 (PRKCA)
04270 Vascular smooth muscle contraction
105599331 (PRKCA)
09154 Digestive system
04970 Salivary secretion
105599331 (PRKCA)
04971 Gastric acid secretion
105599331 (PRKCA)
04972 Pancreatic secretion
105599331 (PRKCA)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
105599331 (PRKCA)
04961 Endocrine and other factor-regulated calcium reabsorption
105599331 (PRKCA)
09156 Nervous system
04724 Glutamatergic synapse
105599331 (PRKCA)
04727 GABAergic synapse
105599331 (PRKCA)
04725 Cholinergic synapse
105599331 (PRKCA)
04728 Dopaminergic synapse
105599331 (PRKCA)
04726 Serotonergic synapse
105599331 (PRKCA)
04720 Long-term potentiation
105599331 (PRKCA)
04730 Long-term depression
105599331 (PRKCA)
04723 Retrograde endocannabinoid signaling
105599331 (PRKCA)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105599331 (PRKCA)
09158 Development and regeneration
04360 Axon guidance
105599331 (PRKCA)
09159 Environmental adaptation
04713 Circadian entrainment
105599331 (PRKCA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105599331 (PRKCA)
05206 MicroRNAs in cancer
105599331 (PRKCA)
05205 Proteoglycans in cancer
105599331 (PRKCA)
05207 Chemical carcinogenesis - receptor activation
105599331 (PRKCA)
05231 Choline metabolism in cancer
105599331 (PRKCA)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105599331 (PRKCA)
05214 Glioma
105599331 (PRKCA)
05223 Non-small cell lung cancer
105599331 (PRKCA)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105599331 (PRKCA)
05161 Hepatitis B
105599331 (PRKCA)
05171 Coronavirus disease - COVID-19
105599331 (PRKCA)
05164 Influenza A
105599331 (PRKCA)
05163 Human cytomegalovirus infection
105599331 (PRKCA)
09174 Infectious disease: parasitic
05146 Amoebiasis
105599331 (PRKCA)
05143 African trypanosomiasis
105599331 (PRKCA)
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
105599331 (PRKCA)
05022 Pathways of neurodegeneration - multiple diseases
105599331 (PRKCA)
09165 Substance dependence
05031 Amphetamine addiction
105599331 (PRKCA)
05032 Morphine addiction
105599331 (PRKCA)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105599331 (PRKCA)
05415 Diabetic cardiomyopathy
105599331 (PRKCA)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105599331 (PRKCA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105599331 (PRKCA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
caty01001
]
105599331 (PRKCA)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
caty04131
]
105599331 (PRKCA)
Enzymes [BR:
caty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
105599331 (PRKCA)
Protein kinases [BR:
caty01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
105599331 (PRKCA)
Membrane trafficking [BR:
caty04131
]
Endocytosis
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
105599331 (PRKCA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
C1_1
C2
Pkinase_C
C1_2
ABC1
Motif
Other DBs
NCBI-GeneID:
105599331
NCBI-ProteinID:
XP_011944883
Ensembl:
ENSCATG00000031179
UniProt:
A0A2K5LMT6
LinkDB
All DBs
Position
Unknown
AA seq
672 aa
AA seq
DB search
MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN
PQFVHPILQSAV
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcgcgcttcttcaagcagcccaccttctgcagccactgcacggacttcatctgggggttt
gggaaacagggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccccaggagc
aagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtcc
ctgctgtatggacttatccaccaagggatgaaatgtgacacctgcgatatgaacgttcac
aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacacagagaagaggggg
cggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacgagatgca
aaaaatctaatccctatggatccaaatgggctttcagatccttatgtgaagctgaaactt
attcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactaaat
ccccagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc
tttggggtttcggagctaatgaagatgccagccagtggatggtacaagttgcttaaccaa
gaagaaggtgagtactacaatgtacccattccagaaggggacgaagaaggaaacatggaa
ctcaggcagaaattcgagaaagccaagcttggccctgctggcaacaaagtcatcagtccc
tctgaagacaggaaacaaccttccaacaacctggaccgagtgaaactcaccgacttcaat
ttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgccgacaggaagggc
acagaagaactgtatgcaatcaaaatcctgaagaaggatgtggtgattcaggatgacgac
gtggagtgcaccatggtagaaaagcgagtcttggccctgcttgacaaacccccgttcttg
acgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatggaatatgtc
aacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca
gtattctatgcagcagagatttccatcggattgttctttcttcataaaagaggaatcatt
tatagggatctgaagttagataacgtcatgttggattcagaaggacatatcaaaattgct
gactttgggatgtgcaaggaacacatgatggatggagtcacgaccaggaccttctgtggg
actccagattacatcgccccagagattatcgcttatcagccatatggaaaatctgtggac
tggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggt
gaagatgaggacgagctatttcagtctatcatggagcacaacgtttcctatccaaaatcc
ttgtccaaggaggctgtttccatctgcaaaggactgatgaccaaacacccagccaagcgg
ctgggctgcgggcctgagggggagagggacgtgagagaacatgctttcttccggaggatc
gactgggaaaaactggagaacagggagatccagccaccgttcaagcccaaagtgtgcggc
aaaggagcagaaaactttgacaagttcttcacacgagggcagcccgtcttaacaccgcct
gatcagctggttattgctaacatagaccagtctgattttgaagggttctcgtatgtcaac
ccccagtttgtgcaccccatcttacagagtgcagtatga
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integrated database retrieval system