Cercocebus atys (sooty mangabey): 105600415 Help Entry 105600415         CDS       T07242                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism caty  Cercocebus atys (sooty mangabey) Pathway caty04064   NF-kappa B signaling pathway caty04066   HIF-1 signaling pathway caty04145   Phagosome caty04151   PI3K-Akt signaling pathway caty04217   Necroptosis caty04613   Neutrophil extracellular trap formation caty04620   Toll-like receptor signaling pathway caty04621   NOD-like receptor signaling pathway caty04936   Alcoholic liver disease caty05132   Salmonella infection caty05133   Pertussis caty05134   Legionellosis caty05135   Yersinia infection caty05140   Leishmaniasis caty05142   Chagas disease caty05144   Malaria caty05145   Toxoplasmosis caty05146   Amoebiasis caty05152   Tuberculosis caty05161   Hepatitis B caty05162   Measles caty05164   Influenza A caty05170   Human immunodeficiency virus 1 infection caty05171   Coronavirus disease - COVID-19 caty05205   Proteoglycans in cancer caty05235   PD-L1 expression and PD-1 checkpoint pathway in cancer caty05321   Inflammatory bowel disease caty05323   Rheumatoid arthritis caty05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:caty00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     105600415 (TLR4)    04066 HIF-1 signaling pathway     105600415 (TLR4)    04151 PI3K-Akt signaling pathway     105600415 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     105600415 (TLR4)   09143 Cell growth and death    04217 Necroptosis     105600415 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     105600415 (TLR4)    04620 Toll-like receptor signaling pathway     105600415 (TLR4)    04621 NOD-like receptor signaling pathway     105600415 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     105600415 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105600415 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105600415 (TLR4)    05161 Hepatitis B     105600415 (TLR4)    05171 Coronavirus disease - COVID-19     105600415 (TLR4)    05164 Influenza A     105600415 (TLR4)    05162 Measles     105600415 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     105600415 (TLR4)    05135 Yersinia infection     105600415 (TLR4)    05133 Pertussis     105600415 (TLR4)    05134 Legionellosis     105600415 (TLR4)    05152 Tuberculosis     105600415 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     105600415 (TLR4)    05144 Malaria     105600415 (TLR4)    05145 Toxoplasmosis     105600415 (TLR4)    05140 Leishmaniasis     105600415 (TLR4)    05142 Chagas disease     105600415 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     105600415 (TLR4)    05321 Inflammatory bowel disease     105600415 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105600415 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105600415 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:caty04131]     105600415 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:caty04054]     105600415 (TLR4)    04090 CD molecules [BR:caty04090]     105600415 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:caty00536]     105600415 (TLR4) Membrane trafficking [BR:caty04131]  Endocytosis   Phagocytosis    Toll-like receptors     105600415 (TLR4) Pattern recognition receptors [BR:caty04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    105600415 (TLR4) CD molecules [BR:caty04090]  Proteins   105600415 (TLR4) Glycosaminoglycan binding proteins [BR:caty00536]  Hyaluronan   Cell surface receptors    105600415 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 TIR_2 LRR_9 LRR_5 LRR_Zer-1 LRR_6 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Motif Other DBs NCBI-GeneID:  105600415 NCBI-ProteinID:  XP_011946973 Ensembl:  ENSCATG00000043557 LinkDB All DBs Position Unknown AA seq 843 aa AA seqDB search MTSALRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNIPFSTKNLD LSFNPLRHLGSYSFLRFPELQVLDLSRCEIQIIEDGAYQSLSHLSTLILTGNPIQSLALG AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL DLSNNKIQNIYCKDLQVLHQMPLPNLSLDLSLNPINFIQPGAFKEIRLRKLTLRSNFDDL NVMKTCIQGLAGLEVHRLVLGEFRNERNLEEFDKSALEGLCNLTIEEFRLTYLDYYLNNI IDLFNCLANVSSFSLVSVNIKGVEDFSYNFRWQHLELVNCKFEQFPTLELESLKRLTFTA NKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNDVITMGSNFLG LEQLEHLDFQHSNLKQMSQFSVFLSLRNLVYLDISHTHTTVAFNGIFDGLLSLKVLKMAG NSFQENFLPDIFTDLKNLTFLDLSQCQLKQLSPKAFETLNKLQVLNMSHNNFFSLDMFPY KSLPSLQVLDYSLNHIMTSKNQEPQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQL LVEAERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVFSVLVVSVVAVLVYKFYFHLML LAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR QQVELYRLLSRNTYLEWEDSVLGQHIFWRRLRKALLDGRSWNPEEQWVQDAISKKQQLSE EEK NT seq 2532 nt NT seq  +upstreamnt  +downstreamnt atgacgtctgccttgcgcctggctgggactctgatcccagccatggccttcctctcctgc gtgagaccagaaagctgggagccctgcgtggaggtggttcctaacattacttatcaatgc atggagctgaatttctacaaaatccccgacaacatccccttctcaaccaagaacctggac ctgagctttaatcccctgaggcatttaggcagctatagcttcctccgttttccagaactg caggtgctggatttatccaggtgtgaaatccagataattgaagatggggcatatcagagc ctaagccacctctccaccttaatattgacaggaaaccccatccagagtttagccctggga gccttttctggactatcaagtttacagaagctggtggctgtggagacaaatctagcatct ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat cttatccagtctttcaaattacctgagtatttttctaatctgacgaatctagagcacttg gacctttccaataacaagattcaaaatatttattgcaaagacttgcaggttctacatcaa atgcccctacccaatctctctttagacctgtccctgaaccctataaactttatccaacca ggtgcatttaaagaaattaggcttcgtaagctgactttgagaagtaattttgatgattta aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcgtttggttctg ggagaatttagaaatgaaagaaacttggaagagtttgacaaatctgctctggagggattg tgcaatttgaccattgaagaattccgattaacatacttagactactacctcaataatatt attgacttatttaattgtttggcaaatgtttcttcattttccctggtgagtgtgaatatt aaaggggtagaagacttttcttataatttcagatggcaacatttagaattagttaactgt aaatttgaacagtttcccacattggaactcgaatctctcaaaaggcttactttcactgcc aacaaaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaccagc ctaaagtatttagatctgagcttcaatgatgttattaccatgggttcaaacttcttgggc ttagaacaactagaacatctggatttccagcattccaatttgaaacagatgagtcaattt tcagtattcctatcactcagaaacctcgtttaccttgacatttctcatactcacaccaca gttgctttcaatggcatcttcgatggcttgctcagtctcaaagtcttaaaaatggctggc aattctttccaggaaaacttccttccagatatcttcacagatctgaaaaacttgaccttc ctggacctctctcagtgtcaactgaagcagttgtctccaaaagcatttgagacactcaac aagcttcaggtactaaatatgagccacaacaacttcttttcattggatatgtttccttat aagtctctgccctccctccaggttctcgattacagtctcaatcacataatgacttccaaa aaccaggaacctcagcattttccaagtagtctagctttcttaaatcttactcagaatgac tttgcttgtacttgtgaacaccagagtttcctgcagtggatcaaggaccagaggcagctc ttggtggaagctgaacgaatggaatgtgcaacaccttcagataaacagggcatgccggtg ctgagtttgaatattacctgtcagatgaataagaccatcattggtgtgtctgtgttcagt gtgcttgtggtatctgttgtagcagttctggtctataagttctattttcacctgatgctt cttgctggctgcataaagtatggtagaggtgaaaacatctatgatgcctttgttatctac tcaagccaggatgaggactgggtaaggaatgagctagtaaagaatttagaagaaggggtg cctccctttcagctctgccttcactacagagactttattcccggtgtggccattgctgca aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtagtgtcccagcac ttcatccagagccgctggtgtatctttgaatatgagattgctcagacctggcagtttctg agcagtcgtgcaggcataatcttcattgtcctgcagaaggtggagaagaccctgctcagg cagcaggtggagctgtaccgccttctcagcaggaacacttacctggagtgggaagacagt gtcctagggcagcacatcttctggagacgactcagaaaagccctgctggatggcagatcg tggaatccagaagaacagtgggtacaggatgcaattagcaagaagcaacaactatctgaa gaggaaaaataa

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