KEGG   Cercocebus atys (sooty mangabey): 105600541
Entry
105600541         CDS       T07242                                 
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty04014  Ras signaling pathway
caty04137  Mitophagy - animal
caty04140  Autophagy - animal
caty04620  Toll-like receptor signaling pathway
caty04621  NOD-like receptor signaling pathway
caty04622  RIG-I-like receptor signaling pathway
caty04623  Cytosolic DNA-sensing pathway
caty04657  IL-17 signaling pathway
caty04936  Alcoholic liver disease
caty05014  Amyotrophic lateral sclerosis
caty05022  Pathways of neurodegeneration - multiple diseases
caty05135  Yersinia infection
caty05160  Hepatitis C
caty05161  Hepatitis B
caty05162  Measles
caty05163  Human cytomegalovirus infection
caty05164  Influenza A
caty05165  Human papillomavirus infection
caty05167  Kaposi sarcoma-associated herpesvirus infection
caty05168  Herpes simplex virus 1 infection
caty05169  Epstein-Barr virus infection
caty05170  Human immunodeficiency virus 1 infection
caty05171  Coronavirus disease
caty05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:caty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    105600541 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105600541 (TBK1)
   04137 Mitophagy - animal
    105600541 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105600541 (TBK1)
   04621 NOD-like receptor signaling pathway
    105600541 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    105600541 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    105600541 (TBK1)
   04657 IL-17 signaling pathway
    105600541 (TBK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105600541 (TBK1)
   05161 Hepatitis B
    105600541 (TBK1)
   05160 Hepatitis C
    105600541 (TBK1)
   05171 Coronavirus disease
    105600541 (TBK1)
   05164 Influenza A
    105600541 (TBK1)
   05162 Measles
    105600541 (TBK1)
   05168 Herpes simplex virus 1 infection
    105600541 (TBK1)
   05163 Human cytomegalovirus infection
    105600541 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105600541 (TBK1)
   05169 Epstein-Barr virus infection
    105600541 (TBK1)
   05165 Human papillomavirus infection
    105600541 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    105600541 (TBK1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105600541 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    105600541 (TBK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105600541 (TBK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105600541 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:caty01001]
    105600541 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:caty04131]
    105600541 (TBK1)
Enzymes [BR:caty01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     105600541 (TBK1)
Protein kinases [BR:caty01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   105600541 (TBK1)
Membrane trafficking [BR:caty04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    105600541 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 DUF713 Kinase-like CEP63 ubiquitin DUF2730
Other DBs
NCBI-GeneID: 105600541
NCBI-ProteinID: XP_011947270
Ensembl: ENSCATG00000041854
UniProt: A0A2K5NLV6
LinkDB
Position
Unknown
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQFLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYVHSYNTATIFHELVYKQTKILSSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQE
GTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLSKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttgaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaagagacaacaacaaga
cataaagtacttattatggaattttgcccatgtgggagtttatacactgttttagaagag
ccttctaatgcctatggactaccagaatctgaattcttaattgttttgcgagatgtggtg
ggtggaatgaatcatcttcgagagaatggcatagtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtatacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
caccctgatatgtatgagagagcagtactaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccctttgaagggcctcgtaggaataaagaagtgatgtataaaataattacagga
aagccttctggtgcaatatctggagtacagaaggcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgcagtctttctcggggtcttcagtttctacttacccctgtt
cttgcaaacatccttgaagcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatgttcatagctataatactgctactatatttcatgaactggtatat
aaacaaaccaaaattctttcttcaaatcaagaacttatctatgaagggcgacgcttagtc
ttagaacctggaagactggcacagcatttccctaaaactactgaggaaaaccccatattt
gtagtaagccgggaacctctgaataccataggattaatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggggatgctagcatggctaaggcaataacaggg
gttgtgtgttatgcctgcagaattgccagtaccttactgctttatcaggaattaatgcga
aaggggatacgatggctgattgaattaattaaagatgattacaatgaaactgttcacaaa
aagacagaagttgtgatcacattggatttctgtatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttaatgaagatcaacctagaagcggcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgacagcagattatctccaggtggatcgctggcagatgcatgggcacatcaagaa
ggcactcatccaaaagatagaaatgtagaaaaactacaagtcctgttaaattgcatgaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattaccatgcaaccaaagctatgacgcac
tttacagatgaatgtgttaaaaagtacgaggcatttttgagtaagtcggaagaatggatg
agaaagatgcttcatcttaggaaacagttattatctctgactaatcagtgttttgatatt
gaagaggaagtatcaaaatatcaagactatactaatgagttacaagaaactctgcctcag
aaaatgtttgccgcttccagtggaatcaaacataccatgactccaatttatccaagttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagagatggaaggggtg
gttaaagaacttgctgaaaataaccacattttagaaaggtttggctctttaaccatggat
ggtggccttcgcaacgttgactgtctttag

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