KEGG   Carassius auratus (goldfish): 113056299
Entry
113056299         CDS       T07313                                 
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2-like
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
caua  Carassius auratus (goldfish)
Pathway
caua04010  MAPK signaling pathway
caua04012  ErbB signaling pathway
caua04020  Calcium signaling pathway
caua04510  Focal adhesion
caua04520  Adherens junction
caua04530  Tight junction
Brite
KEGG Orthology (KO) [BR:caua00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113056299
   04012 ErbB signaling pathway
    113056299
   04020 Calcium signaling pathway
    113056299
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113056299
   04520 Adherens junction
    113056299
   04530 Tight junction
    113056299
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:caua01001]
    113056299
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:caua04147]
    113056299
   04090 CD molecules [BR:caua04090]
    113056299
Enzymes [BR:caua01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     113056299
Protein kinases [BR:caua01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   113056299
Exosome [BR:caua04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   113056299
CD molecules [BR:caua04090]
 Proteins
  113056299
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like APH
Other DBs
NCBI-GeneID: 113056299
NCBI-ProteinID: XP_026078729
Ensembl: ENSCARG00000012928
UniProt: A0A6P6L2E3
LinkDB
Position
37:13915910..13947876
AA seq 1272 aa
MEADRSFGLVWVLLLLLGITAASGREVCLGTDMKLALPSSLENHYEMLRLLYTGCQVVHG
NLEITHLQGNPDLSFLQGIVEVQGYVLIAHVSVRSVPLDNLRIIRGSQLYNSSYALAVHN
NIHHSQTGLGLREIRLRSLTEILLGGVYIWGNPQLCFPQNINWEDTVTKVESKPLHLQDI
PKNCPKCSPDCPSNSGCWGETNQDCQTLTSVHCSSGCLRCKGTKPNDCCHVQCAAGCTGP
KDTDCLACRHFNDSGTCKDNCPPPTIYDPNTFQSKPNKDKKFSFGATCVKQCPHNYLAME
VACTMVCPKANKEVITVEPDGQETQKCEKCEGECPKVCYGLGMGNLQGVSVVDATNIGMF
VGCEKIYGSLAFLSDSFKVNAATNSSGLQRSDLEKLKTIEEITGYLYIDAWPDNLLDLSV
FENLKVIRGRMLYKGVFSLGVQSLQIESLGLRSLRSVSGGIVLIHNNSRLCYTSSLPWSS
LLHPTQGPNLISNNNQDQQTCVSEGRVCDPLCADAGCWGPGPSQCVSCLNYKRGTECVEQ
CNVVQGSVREFVDGLNCVPCHPECKPVNDSASCTGPGPEHCKECLQYQDGDVCVDRCPSG
VKEDQHTVWKYPNETHHCLPCETNCTVSCPLDDRGCPIQKKTGAGTTVAVTVGGVLLFFI
LLALLVFYLRRQKHHKMKENIRRMQQEHELVEPLTPSGAVPNQAQMRILKETELKKVRVL
GSGAFGTVYKGIWAPDGENIKIPVAIKVLRENTSPKANKEILDEAYVMAGVSSPYVCRLL
GICLTSTVQLVTQLMPYGCLLDYVRENQDRIGSQYLLNWCVQIAKGMSYLEDVRLVHRDL
AARNVLVKNPNHVKITDFGLARLLDIDEKEYHADGGKVPIKWMALESILHRKFTHQSDVW
SYGVTVWELMTFGMKPYDQIPAREIPDLLERGDRLPQPLNCTSDVYMIMVKCWMIDPESR
PRFKKLVEEFSIMARDPPHYVVIVNDDQKSLSSPVDSEFFRTLLAEEGVNVKEFLDAEEY
LVPQPGGIFNTQGEMRANGPSRHHSHRSTDQGLEVDGMPSGMDLYSSLSTPRESPYQTLP
VRESVNGMWPGTQYPPLVRSISHHSAGSQSDSVFVDGYIEDNGPPSSPCRYSKDPTIPNG
IDGELVTDGPISFLSHTLPRGAHTHPEYVNQHVSSDRPSTLPRKARERRFVNGLHTGNSV
ENPEYLVPVHSISPAFDNPYYHDIAAKAQAVARASINGGTTHRQPNGYMTPTAENPEYLG
LAETWSGQLEYT
NT seq 3819 nt   +upstreamnt  +downstreamnt
atggaggcagacagaagttttgggctcgtctgggtcctgctgctgctgttgggtattaca
gccgcttcagggagagaagtatgtcttgggactgatatgaagttggctttaccctccagt
cttgagaatcattatgaaatgctcaggctgctgtacacgggctgccaggtggttcatggg
aacctggagatcacacacctgcagggaaatccagatctctccttcctgcaggggattgtg
gaggttcaggggtatgtgctgatagctcacgtctccgtgcgttcggttcctctggacaat
ctgcgtatcatacgaggcagtcagctttataactccagctatgctctcgctgtacataac
aacatccaccacagtcagacgggactcggcttgagagaaatacgcctcaggagtcttaca
gagatcttgcttggcggggtttatatttggggaaatcctcaactttgctttcctcagaat
attaactgggaagacacggttactaaagttgaaagcaaaccgctgcacctgcaagacatc
ccgaagaactgtcccaaatgttctccagattgtccttcaaacagtggatgctggggagaa
acaaatcaggactgccaaacattgacctctgtgcattgctcatctggctgtttgcgctgt
aagggcacaaaacccaatgactgctgtcatgtacagtgtgctgctgggtgcacggggcca
aaagacacggactgtctggcctgtcgtcacttcaatgacagtgggacatgtaaagacaac
tgccccccacccaccatctatgacccgaacactttccagtccaaacccaacaaggacaaa
aagttcagctttggagccacatgtgttaaacagtgtccccataactatttggcaatggaa
gtggcatgtacaatggtctgtcccaaagctaacaaggaagttatcactgttgagccagat
ggccaagaaacacagaaatgtgaaaagtgtgaaggagagtgtccgaaagtgtgttatgga
ctaggaatgggaaaccttcaaggggtgtcagtggtggatgccaccaacattggcatgttc
gttggctgtgagaaaatctacggcagtttggcttttctttcagactccttcaaagtaaat
gcagctaccaattcatctggactgcagcggagtgacctggagaagttaaagacaatagaa
gaaatcacaggatacctgtacatagatgcatggccagacaatttgcttgatttgagtgtt
tttgagaacttgaaggtcatcagaggaagaatgctttacaagggtgttttctctttggga
gttcagtctttgcagatcgagtctctcgggttgcgttccttgcgcagtgtcagtggaggc
atagtactgattcataataactccagactgtgctacacctcctctctgccctggagctcg
ctgctccaccccacacagggacccaacctcatcagcaacaacaaccaagaccagcaaaca
tgtgtttcagaggggagagtttgtgaccccctgtgtgcggatgcaggctgctgggggcca
ggacctagtcagtgtgtgtcgtgtttgaattacaaacgtgggacggagtgtgtggagcag
tgtaatgtagtacaggggtctgtgcgggagtttgtggatggactgaactgtgtcccttgc
catccagagtgtaaaccagtcaatgactctgcctcatgtacaggcccaggtccagaacat
tgtaaggagtgtctgcagtatcaagacggagatgtgtgtgtcgatcgctgccccagtggg
gtaaaggaggaccagcacactgtgtggaagtaccccaacgaaacacaccactgtctgccc
tgcgaaaccaactgcactgtctcgtgtccactggatgatagagggtgtcccatccaaaag
aaaactggggctgggacaacagtcgcagtcacagttggcggagtgcttcttttcttcatt
ttgctggcactgctggtgttttacctgcgacgacagaaacaccacaaaatgaaagaaaac
ataaggagaatgcaacaggagcatgagctggtggagcccctgaccccgagtggagcggtg
ccgaaccaagctcagatgcgtattctcaaggagacagagctgaagaaagtccgagtgctg
ggttctggagccttcggcacggtctataagggtatctgggctccagatggggagaacatc
aagatcccagtggccatcaaagttttgcgtgagaacacctcgcccaaagccaacaaagaa
atcctggatgaggcatatgtgatggcgggtgtatcaagcccatatgtttgccgtttgctg
ggtatctgtctgacatccacagttcagctggttactcagctcatgccgtatgggtgcttg
ttggactacgtcagggagaaccaggatcgtatcggctctcagtaccttctcaactggtgt
gtacagattgctaagggaatgagttaccttgaagatgtcaggctggttcacagagacctt
gcagctaggaatgttctggtcaaaaacccaaaccatgtaaagatcacagactttgggctt
gccaggctgctggacatagatgagaaggagtaccatgctgatgggggaaaggtgccgatc
aaatggatggcactcgaatccatattacaccggaagtttactcaccaaagtgacgtatgg
agctacggggtgactgtgtgggagttgatgacctttggcatgaagccatatgaccagata
ccagcgcgggaaattccagacctactggagagaggagatagactcccgcagccgttgaac
tgtacctcagatgtatacatgatcatggtcaaatgttggatgattgatcctgaaagtcga
ccacgatttaagaagctggtggaggagttcagcatcatggcacgtgatcccccacattat
gtagtcattgtgaatgatgatcagaaaagtctttcgagtcctgttgacagtgagttcttc
cgcacgctgctggcagaagagggagtgaatgtgaaggagttcctggatgcagaagaatac
ctggtgccccagcctggtggcatcttcaatacacaaggagaaatgagagccaatggacct
agcagacaccactctcaccggagtacagatcaaggattagaggtggatggtatgccgagc
gggatggatttgtactcttccctcagcaccccaagggaaagtccataccaaactcttcct
gtgagggaatcagtcaatggcatgtggcctggtacacaatacccacctttggtacggagc
atatcacaccattcagccggcagccaatcagactctgtgtttgtggatggttacatagag
gataacggccctccatccagtccttgtcgctattctaaagaccccaccatccccaacggc
atagatggagaactggtgactgatggtcctatcagtttcctttcacacacactgccacgt
ggagcacacacacatcctgagtatgtgaaccagcacgtgtcatcagaccgtcccagcaca
cttccacgcaaagcgagagagaggagattcgttaacggtcttcatacagggaacagtgtg
gagaacccagagtacctggtgccagtgcacagcatctcacccgccttcgacaacccctac
tatcatgatattgcagctaaagctcaggcagtcgccagagcgtccataaacggaggtact
actcacaggcagcccaatggctacatgacccccacggcagaaaacccagagtacctgggc
ttagcagagacatggagtggtcagttggagtatacttga

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