Clostridium acetobutylicum EA 2018: CEA_G3175
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Entry
CEA_G3175 CDS
T01864
Symbol
leuB
Name
(GenBank) Isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
cay
Clostridium acetobutylicum EA 2018
Pathway
cay00290
Valine, leucine and isoleucine biosynthesis
cay00660
C5-Branched dibasic acid metabolism
cay01100
Metabolic pathways
cay01110
Biosynthesis of secondary metabolites
cay01210
2-Oxocarboxylic acid metabolism
cay01230
Biosynthesis of amino acids
Module
cay_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cay00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CEA_G3175 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CEA_G3175 (leuB)
Enzymes [BR:
cay01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
CEA_G3175 (leuB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Iso_dh
DUF6259
ERp29
DUF276
Motif
Other DBs
NCBI-ProteinID:
ADZ22212
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All DBs
Position
complement(3305958..3307031)
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AA seq
357 aa
AA seq
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MKEYKVAVIPGDGIGVEIVGEALKVLEKVGAKYDTKFNFTEVKAGGCAIDEFGVPLPNET
LEICKNSDAVLLGAVGGPKWDTLPGEKRPEKALMGLRGGLGLYANLRPAKVYDILKSASP
LKEEIINKGVDLLVVRELTGGIYFGERGRDIQNGINSAYDTERYNVEEIKRIAHVAFKAA
LKRNKKVTSVDKANILESSRLWRETVTEVAKEYPEVELNYLYVDNAAMQLVREPSQFDVI
VTSNIFGDILTDEASMVTGSIGMLPSASLRNDTFGMYEPIHGSAPDIAGQDLANPLAQIL
SVAMMLEYSFNMTEAARDVEDAVEKVLNSGYRTGDIYTEGSKKVGTKEMGKLVLAEL
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaatataaggtggccgttatacctggtgatggaatcggtgttgaaatagtagga
gaagctcttaaggttcttgaaaaagtaggagcgaaatacgatactaagtttaattttaca
gaggttaaggcaggaggatgtgctatagatgaatttggagtacctcttccaaacgaaact
ttagaaatctgtaaaaactcggatgcagtacttttgggagcggtaggaggacctaagtgg
gatactcttccgggagaaaaaagacctgaaaaggctcttatgggtttaagaggtggactt
ggactttatgctaacttaagaccagcaaaggtttatgatattttaaaatctgcatctcct
ttaaaggaagaaatcataaacaagggagtagatttacttgttgtaagagagcttacagga
ggaatttactttggagaaagaggaagagatattcaaaacggaataaactcagcttatgat
actgaaagatataatgtagaagagataaagagaattgcacatgttgcttttaaagctgct
cttaagagaaataagaaggttacttctgtagataaagcaaatatattggaatcttcaagg
ctttggagagaaacagtaacagaggttgcaaaggaatatccagaggttgaattaaactat
ctttacgttgataatgcagcaatgcagcttgtacgtgaaccatcacaatttgatgtaata
gtaaccagcaacatattcggagatattcttacagatgaggcttcaatggtaacaggctca
ataggaatgctgccatcggcaagtcttagaaatgatacttttggaatgtatgagccaata
cacggttctgcaccagatattgcaggacaagatttagcaaatccattagcacaaatatta
tcagttgcaatgatgcttgaatattcatttaatatgactgaagctgcaagagatgtagaa
gatgcagtagaaaaagttttaaatagtggatacagaactggtgatatatacacagaagga
agtaaaaaagttggaacaaaagaaatgggtaagcttgttttagctgaactttaa
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