Serpentinimonas maccroryi: SMCB_0401
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Entry
SMCB_0401 CDS
T03627
Symbol
leuA
Name
(GenBank) isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cbab
Serpentinimonas maccroryi
Pathway
cbab00290
Valine, leucine and isoleucine biosynthesis
cbab00620
Pyruvate metabolism
cbab01100
Metabolic pathways
cbab01110
Biosynthesis of secondary metabolites
cbab01210
2-Oxocarboxylic acid metabolism
cbab01230
Biosynthesis of amino acids
Module
cbab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cbab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SMCB_0401 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMCB_0401 (leuA)
Enzymes [BR:
cbab01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SMCB_0401 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
BAO82629
UniProt:
A0A060NUP9
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Position
445023..446573
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AA seq
516 aa
AA seq
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MSDKLIIFDTTLRDGEQSPGASMTKDEKLRIARQLERLKVDVIEAGFAAASNGDFEAVKA
IADAIKDSTVCSLARANERDISRSAEALAGARSARIHTFIATSALHMEKKLRMTPEQVFE
QAQQAVRLARQLCPDVEFSPEDGYRSDPDFLCRVIEAVISAGARTINIPDTVGYGVPELY
GHFIRDLRERVPNSDLAVWSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNC
ALEEIVMAIKTRRDYYGLEVGIDTTQIVPASRMVSQTTGFVVQPNKAVVGANAFAHASGI
HQDGVLKARATYEIMRAEDVGWSANKIVLGKLSGRNAFKQRLDEIGIALHSEVELNAAFA
KFKELADRKSEIFDEDILALVSDESVTPDQEHYALVALAQHSETGERPQARVVFTIGGKE
YCGQAEGNGPVDASLKAIETHVHSGAELQLYSVNAITSGSTESQGEVTVRLQHAGRVVNG
VGSDPDIVVASAKAYLSALTKLHSKAERVQAQGWPV
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacaaactgatcatttttgataccaccttgcgcgacggcgagcagtcgcccggc
gcttccatgaccaaggacgagaagctgcgcatcgcgcgccagctcgagcgcctgaaggtg
gacgtgatcgaggctggctttgccgccgcctccaacggcgacttcgaagccgtcaaggcc
atcgccgacgccatcaaagacagcaccgtctgttcgctggcgcgcgccaacgaacgcgac
atcagccgctcggccgaggcgctggccggcgcgcgcagcgcccgcatccacaccttcatc
gccaccagcgcgctgcacatggaaaaaaagctgcgcatgacgcccgagcaggtgtttgag
caggcgcagcaggcggtgcggctggcgcgccagctctgccccgacgtcgagttcagcccc
gaagacggctaccgcagcgaccccgactttttgtgccgcgtcatcgaggcggtgatcagc
gccggcgcgcgcaccatcaacatccccgacaccgtgggctacggcgtgcccgaactctac
ggccacttcatccgcgacctgcgcgagcgcgtgcccaactccgacctcgcggtctggagc
gtgcactgccacaacgatctgggcatggcggtggccaactcgctcgccggcgtcaagatc
ggcggcgcgcgccaggtcgagtgcaccatcaacggcttgggtgagcgcgccggcaactgc
gcgctcgaagaaatcgtcatggccatcaaaacgcggcgcgattactacggccttgaagtc
ggcatcgacaccacgcagatcgtgcccgccagccgcatggtcagccagaccaccggcttt
gtggtgcagcccaacaaggccgtggtcggggccaacgcctttgcccacgccagcggcatc
caccaagacggcgtgctcaaggcgcgcgccacctacgagatcatgcgcgccgaagacgtg
ggctggagcgccaacaagatcgtgctcggcaagctcagcggccgcaacgccttcaagcag
cgcctcgacgagatcgggatcgcgctgcacagcgaagtcgagctcaacgccgcctttgcc
aagttcaaagagctggccgaccgcaagtcggaaatctttgacgaagacattctggcgctg
gtcagcgacgagagcgtgacccccgatcaggagcattacgcgctggtggcgctggcccag
cacagcgagaccggcgagcgcccgcaggcgcgggtggtgttcaccatcggcggcaaagag
tactgcggacaagccgagggcaacggcccggtggatgcgtcgctcaaagccatcgagacc
cacgtgcacagcggcgccgagttgcagctgtattcggtcaacgccatcaccagcggttcg
accgagagccagggcgaagtcacggtgcggctgcagcacgcaggccgggtggtcaacggc
gtgggctccgaccccgacatcgtggtcgcgtcggccaaagcctacctgagtgccctcacc
aaactgcacagcaaggccgagcgggtgcaggcgcagggctggccggtctga
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