Clostridiales bacterium FE2010: JS518_12745
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Entry
JS518_12745 CDS
T08976
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cbaf
Clostridiales bacterium FE2010
Pathway
cbaf00230
Purine metabolism
cbaf01100
Metabolic pathways
cbaf01110
Biosynthesis of secondary metabolites
Module
cbaf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cbaf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
JS518_12745
Enzymes [BR:
cbaf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
JS518_12745
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
QTE73753
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Position
2844742..2848497
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AA seq
1251 aa
AA seq
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MVYRIFVEKKPGLDNEARALLGDAKKFLGIKGLEKVRLLNRYDAENISDDMFSLAVREVF
SEPQLDNTMDQFDAEGAIAVFAVEYLPGQFDQRADSAAQCIQFLSQGERPLVRSAKVYLL
YGSLSAEEIAEIKKYVINPVEAREASMDLPETLKTEYAVPTEVATLEGFTKLDRAGLEKF
VADYGLAMDVDDITFCQSWFREEGREPTITEIRMLDTYWSDHCRHTTFLTEIDSVRFEDP
VLEKAWKRYMDVRAELGREKKPVCLMDLATVAVKYLKKHGKLDKLDESEEINACTVKMDV
ERDGVKEPWLLLFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRAYVYGAMRVTGAADP
TKPVSETIPGKLPQRKLVTTAAAGYASYGNQIGLATGIVDEIYHPGYAAKRMEIGAVIAA
APAENVRRERPAPGDVVILLGGSTGRDGIGGATGSSKAHNAHSVETCGAEVQKGNAPEER
KLQRLFRNPKATRLIKRCNDFGAGGVSVAIGELADGLEIDLNAVPKKYEGLDGTELAISE
SQERMAVVVAAEDAEAFLALSAEENLQACIVAEVKAEPRLRMNWNGKTIVDISREFLNSN
GAPKHTAITPAASHPAADLPKQEPADFAGLLKTTASDLAVCSRRGLSERFDSTIGAGTVL
MPFGGKNQLTPIQAMVQKISLEKGHTDDCSLMAWGYDPELTSFSPYHGAYLAVVDSVTKL
IAAGASFEDVYLTFQEYFEKPGTDGKRWGKPLAALLGAFEAQMNLGVGAIGGKDSMSGSF
EKLDVPPTLVSFAVTTAKTGDIISPEFKKAGHPVVVLEPERDEQGLPVTESLLALYNQVT
GLIREGKIVSCRTAEVGGSLASVLKMALGNGLGFAFEKDWELKELAEVRYGSFIAELSED
MDLGRKLGVVTEEPVLTWRDNAADVKELRVIGRDKLEKVYPTLNPEWSLEDRAEADACWP
AARKEDRTETFNYKANGWKAPALHIAKPGVLIPAFPGTNCEIDSARAAEDAGAKAEIFVV
RNRSAEDIVRSAEEFAAKVRENQMIFIPGGFSGGDEPDGSAKFIIAFFRNQGVTEAVTEM
LDKRDGLMCGICNGFQALIKLGLVPYGKIIETDEHCPTLTFNTIGRHQSRIVRTRVASNL
SPWLRNARQGAVYSVPISHGEGRFLAEESLIRKLAENGQIATQYVDLDDQPTMDLRFNPN
GSLYAIEGITSPDGRVFGKMGHSERVGKDLYKNVPGNYDIKMFESAVQYFR
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
ttggtttacagaatctttgttgaaaaaaagcccggcctggacaatgaagcccgggcactg
ctgggagacgcgaaaaagttcctggggatcaaaggcctggaaaaggtccggctgctgaac
cgctatgacgctgagaacatctcagatgatatgttctccctggcggtccgggaggtgttc
tctgagccccagctggacaatacaatggatcagtttgacgcggaaggcgcgattgccgtg
ttcgcggtggaatacctgcccggtcagtttgaccagcgggcggactccgctgcccagtgc
attcagttcctttcccagggcgagcgtccgctcgtccgcagcgcgaaggtttacctgctc
tacggcagcctgtccgctgaagagatcgcggaaatcaagaagtatgtgatcaacccggtg
gaagcccgggaagcttccatggatctgccggaaaccctgaagacggaatacgcggtgccc
acggaagtggcaaccctggaaggcttcacgaagcttgaccgcgccggcctggagaagttt
gtggcggattacggcctggccatggacgtggatgatatcaccttctgccagtcctggttc
cgggaagaaggccgggaacccaccatcacggaaatccggatgctggacacctactggagc
gaccactgccgtcacaccaccttcctgaccgagatcgacagcgtccgctttgaagatccg
gtgctggagaaggcatggaagcgctacatggatgtgcgcgctgaactcggccgggaaaag
aagccggtgtgcctgatggacctcgccacggttgcggtgaagtacctgaagaagcacggc
aagctggacaagctggacgagagcgaagaaatcaacgcctgcacggtgaagatggacgtg
gagcgggacggggtcaaggagccctggctgctgctgttcaagaatgaaacccacaaccat
cccactgagattgaacctttcggcggcgcggccacctgtatcggcggcgcgatccgggat
cccctgagcggccgggcctatgtttacggcgcgatgcgcgtgaccggtgctgcggatccc
accaagcccgtttctgaaaccatccccggcaagctgccccagcgcaagctggtgactacc
gcggcagccggttatgcttcctacggcaaccagatcggcctggccaccggcattgtggat
gaaatctatcatcccggctacgcggccaagcgtatggagatcggcgcagtgattgccgcg
gctcccgcggaaaatgtacgccgcgagcgtccggctcccggcgacgtggtgatcctgctg
ggcggttccaccggccgtgacggtatcggcggtgccaccggttcctccaaggctcataat
gcccacagcgtggaaacctgcggcgcggaagtccagaagggtaacgcgccggaagagcgc
aagctccagcggctgttccgcaatccgaaggccaccaggctgatcaagcgctgcaatgac
ttcggtgcgggcggcgtcagcgttgccatcggcgagctggcggacggcctggaaatcgac
ctgaacgcggtaccgaagaaatatgaaggcctcgatggtactgagctggccatttccgag
agccaggagcgcatggccgtggttgtggccgcggaagatgcggaagctttcctggccctg
tcggcggaggaaaacctgcaggcctgcatcgtggcggaagtgaaggctgagccgcgcctg
cggatgaactggaacggaaagaccattgtggatatcagccgtgagttcctgaactccaac
ggtgccccgaagcataccgcgattacccccgcagcttcccatcccgccgcggatctgccg
aagcaggagcccgcggactttgcggggctgctgaagaccacggcttccgacctggcggtc
tgctcccgccggggcctgtccgagcggtttgactccaccatcggcgccggcacggtgctg
atgcccttcggcggcaagaaccagctgacccccatccaggcgatggtccagaagatcagc
ctggaaaagggacacacggatgactgctccctgatggcctggggctatgatccggagctg
acctccttcagcccctatcatggtgcctatcttgctgtggtggattctgtcaccaagctg
attgcggccggtgcctcctttgaggacgtgtacctgaccttccaggaatactttgagaaa
cccggaacggacggaaaacgctggggcaagcctctggcggccctgctgggtgcctttgaa
gcccagatgaacctgggtgtcggcgccatcggcggcaaggactctatgtccggttcattt
gaaaagctggatgtgccgcctacgctggtttccttcgcggtgaccacggcaaagaccggc
gacatcatttcccctgagttcaagaaagcgggtcatcccgtggtcgtgctggagccggaa
cgggatgaacagggcctgccggtaacggaatccctgctggctctctacaaccaggtgaca
gggctgatccgtgaaggaaagattgtttcctgccgtacggcagaggttggcggatccctt
gcctctgtgctgaagatggcgctgggcaacggcctgggcttcgcctttgagaaggactgg
gagctgaaggagctggcggaggttcgctacggcagctttatcgcggaactgtccgaagac
atggacctcggccggaagctgggcgttgtgaccgaagaacccgtgctgacctggcgggat
aacgcggcggacgtgaaggagctgcgcgtgatcggccgggacaagctggaaaaagtgtat
ccgaccctgaatccggagtggtccctggaagaccgggcagaagcggacgcctgctggccc
gcggcccgaaaggaagaccggacggaaaccttcaactacaaggccaacggctggaaagcc
ccggccctgcatattgcgaagcccggcgtgctgatcccggcattccccggcaccaactgc
gaaatcgacagcgcccgcgccgcggaagacgccggcgcgaaggcggaaatcttcgtggtc
cggaaccggtccgcggaggatattgtccgcagcgcggaagagtttgccgcgaaggttcgt
gagaaccagatgatcttcatccccggcggcttctccggcggcgatgaaccggacggcagc
gcgaagtttatcatcgccttcttccggaaccagggcgtcaccgaagcggtgaccgagatg
ctggacaagcgggacggccttatgtgcggtatctgtaacggcttccaggccctgatcaag
ctgggactggtgccctacggcaagatcattgaaaccgatgagcactgcccgaccctgacc
ttcaacaccatcggccgccaccagagccggattgtccgcacccgggtggccagcaacctg
agcccctggctgcgcaatgcccggcagggcgcggtttacagcgtgccgatcagccacggc
gaaggccgcttcctggcggaggaaagcctgatccggaagctggcagagaacggacagatt
gccacccagtatgtggatctggacgatcagcccaccatggacctgcgcttcaatcccaac
ggcagcctgtatgccattgaaggtatcaccagcccggacggccgcgtcttcggcaagatg
ggtcacagcgagcgcgttggcaaagacctgtacaagaacgttcccggaaactacgatatc
aaaatgttcgaatctgcggtccagtacttcagataa
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