Camelus bactrianus (Bactrian camel): 105068818 Help Entry 105068818         CDS       T07534                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism cbai  Camelus bactrianus (Bactrian camel) Pathway cbai00230   Purine metabolism cbai01100   Metabolic pathways cbai01522   Endocrine resistance cbai04015   Rap1 signaling pathway cbai04020   Calcium signaling pathway cbai04022   cGMP-PKG signaling pathway cbai04024   cAMP signaling pathway cbai04062   Chemokine signaling pathway cbai04072   Phospholipase D signaling pathway cbai04114   Oocyte meiosis cbai04211   Longevity regulating pathway cbai04213   Longevity regulating pathway - multiple species cbai04261   Adrenergic signaling in cardiomyocytes cbai04270   Vascular smooth muscle contraction cbai04371   Apelin signaling pathway cbai04540   Gap junction cbai04611   Platelet activation cbai04713   Circadian entrainment cbai04714   Thermogenesis cbai04723   Retrograde endocannabinoid signaling cbai04724   Glutamatergic synapse cbai04725   Cholinergic synapse cbai04727   GABAergic synapse cbai04742   Taste transduction cbai04750   Inflammatory mediator regulation of TRP channels cbai04911   Insulin secretion cbai04912   GnRH signaling pathway cbai04913   Ovarian steroidogenesis cbai04914   Progesterone-mediated oocyte maturation cbai04915   Estrogen signaling pathway cbai04916   Melanogenesis cbai04918   Thyroid hormone synthesis cbai04921   Oxytocin signaling pathway cbai04923   Regulation of lipolysis in adipocytes cbai04925   Aldosterone synthesis and secretion cbai04926   Relaxin signaling pathway cbai04927   Cortisol synthesis and secretion cbai04928   Parathyroid hormone synthesis, secretion and action cbai04934   Cushing syndrome cbai04935   Growth hormone synthesis, secretion and action cbai04970   Salivary secretion cbai04971   Gastric acid secretion cbai04972   Pancreatic secretion cbai04976   Bile secretion cbai05032   Morphine addiction cbai05163   Human cytomegalovirus infection cbai05166   Human T-cell leukemia virus 1 infection cbai05200   Pathways in cancer cbai05207   Chemical carcinogenesis - receptor activation cbai05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:cbai00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105068818 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105068818 (ADCY4)    04371 Apelin signaling pathway     105068818 (ADCY4)    04020 Calcium signaling pathway     105068818 (ADCY4)    04072 Phospholipase D signaling pathway     105068818 (ADCY4)    04024 cAMP signaling pathway     105068818 (ADCY4)    04022 cGMP-PKG signaling pathway     105068818 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105068818 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     105068818 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105068818 (ADCY4)    04062 Chemokine signaling pathway     105068818 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     105068818 (ADCY4)    04923 Regulation of lipolysis in adipocytes     105068818 (ADCY4)    04912 GnRH signaling pathway     105068818 (ADCY4)    04913 Ovarian steroidogenesis     105068818 (ADCY4)    04915 Estrogen signaling pathway     105068818 (ADCY4)    04914 Progesterone-mediated oocyte maturation     105068818 (ADCY4)    04921 Oxytocin signaling pathway     105068818 (ADCY4)    04926 Relaxin signaling pathway     105068818 (ADCY4)    04935 Growth hormone synthesis, secretion and action     105068818 (ADCY4)    04918 Thyroid hormone synthesis     105068818 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     105068818 (ADCY4)    04916 Melanogenesis     105068818 (ADCY4)    04925 Aldosterone synthesis and secretion     105068818 (ADCY4)    04927 Cortisol synthesis and secretion     105068818 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105068818 (ADCY4)    04270 Vascular smooth muscle contraction     105068818 (ADCY4)   09154 Digestive system    04970 Salivary secretion     105068818 (ADCY4)    04971 Gastric acid secretion     105068818 (ADCY4)    04972 Pancreatic secretion     105068818 (ADCY4)    04976 Bile secretion     105068818 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     105068818 (ADCY4)    04727 GABAergic synapse     105068818 (ADCY4)    04725 Cholinergic synapse     105068818 (ADCY4)    04723 Retrograde endocannabinoid signaling     105068818 (ADCY4)   09157 Sensory system    04742 Taste transduction     105068818 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     105068818 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     105068818 (ADCY4)    04213 Longevity regulating pathway - multiple species     105068818 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     105068818 (ADCY4)    04714 Thermogenesis     105068818 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105068818 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     105068818 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105068818 (ADCY4)    05163 Human cytomegalovirus infection     105068818 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     105068818 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105068818 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105068818 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105068818 (ADCY4) Enzymes [BR:cbai01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105068818 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  105068818 NCBI-ProteinID:  XP_010953093 UniProt:  A0A9W3EPR0 LinkDB All DBs Position Unknown AA seq 1084 aa AA seqDB search MQRWAGETMARLFSPRPSPSEDLFFAETYYILSQQYPLLLLLLVIVICGLLALLAVASAS GRELASDPGFLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGHGLLFTG GVVSAWDQVSFFLFVIFTVYAMLPLDMREAAAAGLASSLSHLLALGLYLGPQPDSRPALL PQLAANAVLFLCGNVAGAYHKALMERALRATFREALSSLHSRWRLDTEKKHQEHLLLSIL PAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSP KELVLMLNELFGKFDQIAKDHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRA IRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHIT GATLALLAGAYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPK MRPSLLMTRYLESWGAAKPFAHLSHVESPVSTSTPLPERALSSFSPQWSLDRSRTPRGLD DELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACT FLVFLSNFIIQMLVTNRPPALAITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPT LSVLVATQPGLRVALGTATILLVFAMAITSLVFLPAASNCPFRAPNVSSVAFNFSWELPG SLPLISVPYSMHCCVLGLLSCSLFLHMSFELKLLLLLLWLVASCSVFLHSHAWLSDCLVA RLYPGPLDSRPGVLKEPKLMGAICFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREET EMMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNI NHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDSQQDSER SCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTV NVASRMESTGVLGKIQVTEETAGALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRAGP PSSL NT seq 3255 nt NT seq  +upstreamnt  +downstreamnt atgcagcgctgggcaggggagacgatggcccgcctcttcagtccccggccgtcccccagc gaagacctcttcttcgctgagacctactacatcctgagccagcagtacccactgctgcta ctgctgctggtgatcgtgatctgcgggctcctggctctactggctgtcgccagtgccagc ggcagggagctggcctccgaccctggcttcctgaccactgtgctgtgcgcgctgggtggc ttctcgctactgctgggcctggcttcccgtgagcagcgactgcagcgctggacgcgtccc ctgtccggccttgtgtgggcagcgctgctcgcgctaggtcacggcctcctgttcaccggg ggcgtggtgagcgcctgggaccaggtgtcctttttcctttttgtcatcttcacggtgtat gccatgttgcccttggacatgcgggaagccgccgccgcgggcctcgcctcctcactctca catctgctggccctcgggctgtatcttgggcctcagccggactcacggcccgcgctgctg ccgcagctggcagcaaacgcggtgctgttcctgtgcgggaacgtggcgggagcgtaccac aaggctctgatggagcgcgcactgcgcgccacgttccgggaggcgcttagttctctgcac tcacgttggcggctggacaccgagaagaagcaccaggaacaccttctcttgtccatcctt cctgcctacctggcacgagagatgaaggcagagatcatggcacggctgcaggctggacag gggtcacggccagagagcaccaacaacttccacagcctctatgtcaagaggcaccaggga gtcagtgtgctgtatgctgacatcgtgggcttcacacggctggccagtgagtgctcccct aaggaattggtgctcatgctcaacgagctctttggcaagttcgaccagatcgccaaggac catgaatgcatgaggatcaagatcctgggagactgttactactgtgtctctgggctgccg ctctccctgccagaccacgcaatcaattgtgtgcgcatggggctggatatgtgccgggcc atcaggaaacttcgggcagccaccggcgtggatatcaacatgcgtgtgggtgtacactcg ggcagcgtgctctgtggtgtcatcggactgcagaaatggcaatatgatgtctggtcccat gacgttacactggccaaccacatggaggcgagtggagtgccaggacgagtacatatcaca ggggctacactggccctgctggcaggggcttatgctgtggaggatgcagccatggaacac cgggacccataccttcgggagctaggggagcctacctacctggtcattgatccccgggcc gaggaggaggatgagaagggcactgctggagggttgctgtcctctctcgagggccccaag atgcgtccatcactgctgatgacccgctacctggagtcctggggtgcagccaagccattt gcccatctgagccacgtagagagccctgtgtccacctccacccctctcccggagagggcc ctgtcttccttcagcccccagtggagcctggaccggagccgtaccccccggggactggat gatgaactggacactggggatgccaagttcttccaggtcatcgaacagctcaactctcag aaacagtggaaacagtcaaaggacttcaaccctctgacactgtacttcagagagaaggag atggagaaagagtatcggctctctgcactccccgccttcaagtactatgcagcttgcacc ttcctggtttttctctccaacttcatcatccagatgctggtaacaaacaggcccccagct ctggccatcacctatagcatcaccttcctcctcttcttcctcctcctcttcgtctgcttc tcagagcacctgacgaagtgtgtcttgaaaggccccaagatgctgcactggctgcccacg ctctctgtcctggtggccacacagcccggactgcgagtcgccctgggcactgccacaatc ctgctcgtctttgctatggccattaccagcctggtcttcctaccggcagcatcgaactgc cctttccgggctcccaatgtgtcctccgtggctttcaacttctcctgggagctccctggg tccctgcctctcatcagtgtcccatactccatgcactgctgcgtgctggggctcctctcc tgctccctcttcctgcacatgagcttcgaactgaagctgctgttgctcctgctgtggctg gtggcctcctgctccgtcttcctgcactcccacgcgtggctgtccgactgcctcgtcgcc cgcctctatccgggccccttggactccaggccaggggtgctgaaggagcccaaactgatg ggagcgatctgtttctttatcttcttcttcaccctcctcgtcctggctcggcagaatgag tattactgccgcctggacttcctgtggaagaagaagctgaggcaggagcgggaggagaca gagatgatggagaacctgactcggctgctcttggagaatgtactccctgcgcacgtggcc ccccagttcattggccagaatcggcgcaatgaggacctctaccaccagtcctacgagtgt gtttgcgtcctcttcgcctcagtcccagactttaaggagttttactctgaatccaacatc aaccatgaggggctagagtgtctgcggctgctcaatgagataattgctgattttgatgag ctgctctccaagcccaagttcagtggagtagagaaaatcaaaaccatcggcagcacctac atggcagctacaggcttaaatgccacctctggacaggactcacagcaggattctgagcgg agctgcagccaccttggcaccatggtggagtttgccgtggcccttggatctaagctggac gtcatcaacaagcactcattcaacaacttccgcttgcgtgtggggttaaaccatggacct gtggtagccggagtgattggggcccagaagccacaatatgacatctggggcaacacagtg aacgtggccagccgcatggagagtacaggcgtactgggaaagatccaagtgactgaagag acagctggggccctgcagtccttaggctatacctgctacagccggggcatcatcaaggtc aaaggcaaagggcagctctgcacctacttcctgaacacagatttgactcgagctggacct ccctcgtcactctag

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