KEGG   Camelus bactrianus (Bactrian camel): 105069349
Entry
105069349         CDS       T07534                                 
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
cbai  Camelus bactrianus (Bactrian camel)
Pathway
cbai01521  EGFR tyrosine kinase inhibitor resistance
cbai01522  Endocrine resistance
cbai01524  Platinum drug resistance
cbai04010  MAPK signaling pathway
cbai04012  ErbB signaling pathway
cbai04014  Ras signaling pathway
cbai04015  Rap1 signaling pathway
cbai04022  cGMP-PKG signaling pathway
cbai04024  cAMP signaling pathway
cbai04062  Chemokine signaling pathway
cbai04066  HIF-1 signaling pathway
cbai04068  FoxO signaling pathway
cbai04071  Sphingolipid signaling pathway
cbai04072  Phospholipase D signaling pathway
cbai04114  Oocyte meiosis
cbai04140  Autophagy - animal
cbai04148  Efferocytosis
cbai04150  mTOR signaling pathway
cbai04151  PI3K-Akt signaling pathway
cbai04210  Apoptosis
cbai04218  Cellular senescence
cbai04261  Adrenergic signaling in cardiomyocytes
cbai04270  Vascular smooth muscle contraction
cbai04350  TGF-beta signaling pathway
cbai04360  Axon guidance
cbai04370  VEGF signaling pathway
cbai04371  Apelin signaling pathway
cbai04380  Osteoclast differentiation
cbai04510  Focal adhesion
cbai04520  Adherens junction
cbai04540  Gap junction
cbai04550  Signaling pathways regulating pluripotency of stem cells
cbai04611  Platelet activation
cbai04613  Neutrophil extracellular trap formation
cbai04620  Toll-like receptor signaling pathway
cbai04621  NOD-like receptor signaling pathway
cbai04625  C-type lectin receptor signaling pathway
cbai04650  Natural killer cell mediated cytotoxicity
cbai04657  IL-17 signaling pathway
cbai04658  Th1 and Th2 cell differentiation
cbai04659  Th17 cell differentiation
cbai04660  T cell receptor signaling pathway
cbai04662  B cell receptor signaling pathway
cbai04664  Fc epsilon RI signaling pathway
cbai04666  Fc gamma R-mediated phagocytosis
cbai04668  TNF signaling pathway
cbai04713  Circadian entrainment
cbai04720  Long-term potentiation
cbai04722  Neurotrophin signaling pathway
cbai04723  Retrograde endocannabinoid signaling
cbai04724  Glutamatergic synapse
cbai04725  Cholinergic synapse
cbai04726  Serotonergic synapse
cbai04730  Long-term depression
cbai04810  Regulation of actin cytoskeleton
cbai04910  Insulin signaling pathway
cbai04912  GnRH signaling pathway
cbai04914  Progesterone-mediated oocyte maturation
cbai04915  Estrogen signaling pathway
cbai04916  Melanogenesis
cbai04917  Prolactin signaling pathway
cbai04919  Thyroid hormone signaling pathway
cbai04921  Oxytocin signaling pathway
cbai04926  Relaxin signaling pathway
cbai04928  Parathyroid hormone synthesis, secretion and action
cbai04929  GnRH secretion
cbai04930  Type II diabetes mellitus
cbai04933  AGE-RAGE signaling pathway in diabetic complications
cbai04934  Cushing syndrome
cbai04935  Growth hormone synthesis, secretion and action
cbai04960  Aldosterone-regulated sodium reabsorption
cbai05010  Alzheimer disease
cbai05020  Prion disease
cbai05022  Pathways of neurodegeneration - multiple diseases
cbai05034  Alcoholism
cbai05132  Salmonella infection
cbai05133  Pertussis
cbai05135  Yersinia infection
cbai05140  Leishmaniasis
cbai05142  Chagas disease
cbai05145  Toxoplasmosis
cbai05152  Tuberculosis
cbai05160  Hepatitis C
cbai05161  Hepatitis B
cbai05163  Human cytomegalovirus infection
cbai05164  Influenza A
cbai05165  Human papillomavirus infection
cbai05166  Human T-cell leukemia virus 1 infection
cbai05167  Kaposi sarcoma-associated herpesvirus infection
cbai05170  Human immunodeficiency virus 1 infection
cbai05171  Coronavirus disease - COVID-19
cbai05200  Pathways in cancer
cbai05203  Viral carcinogenesis
cbai05205  Proteoglycans in cancer
cbai05206  MicroRNAs in cancer
cbai05207  Chemical carcinogenesis - receptor activation
cbai05208  Chemical carcinogenesis - reactive oxygen species
cbai05210  Colorectal cancer
cbai05211  Renal cell carcinoma
cbai05212  Pancreatic cancer
cbai05213  Endometrial cancer
cbai05214  Glioma
cbai05215  Prostate cancer
cbai05216  Thyroid cancer
cbai05218  Melanoma
cbai05219  Bladder cancer
cbai05220  Chronic myeloid leukemia
cbai05221  Acute myeloid leukemia
cbai05223  Non-small cell lung cancer
cbai05224  Breast cancer
cbai05225  Hepatocellular carcinoma
cbai05226  Gastric cancer
cbai05230  Central carbon metabolism in cancer
cbai05231  Choline metabolism in cancer
cbai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cbai05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cbai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105069349 (MAPK1)
   04012 ErbB signaling pathway
    105069349 (MAPK1)
   04014 Ras signaling pathway
    105069349 (MAPK1)
   04015 Rap1 signaling pathway
    105069349 (MAPK1)
   04350 TGF-beta signaling pathway
    105069349 (MAPK1)
   04370 VEGF signaling pathway
    105069349 (MAPK1)
   04371 Apelin signaling pathway
    105069349 (MAPK1)
   04668 TNF signaling pathway
    105069349 (MAPK1)
   04066 HIF-1 signaling pathway
    105069349 (MAPK1)
   04068 FoxO signaling pathway
    105069349 (MAPK1)
   04072 Phospholipase D signaling pathway
    105069349 (MAPK1)
   04071 Sphingolipid signaling pathway
    105069349 (MAPK1)
   04024 cAMP signaling pathway
    105069349 (MAPK1)
   04022 cGMP-PKG signaling pathway
    105069349 (MAPK1)
   04151 PI3K-Akt signaling pathway
    105069349 (MAPK1)
   04150 mTOR signaling pathway
    105069349 (MAPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105069349 (MAPK1)
   04148 Efferocytosis
    105069349 (MAPK1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105069349 (MAPK1)
   04210 Apoptosis
    105069349 (MAPK1)
   04218 Cellular senescence
    105069349 (MAPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105069349 (MAPK1)
   04520 Adherens junction
    105069349 (MAPK1)
   04540 Gap junction
    105069349 (MAPK1)
   04550 Signaling pathways regulating pluripotency of stem cells
    105069349 (MAPK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105069349 (MAPK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105069349 (MAPK1)
   04613 Neutrophil extracellular trap formation
    105069349 (MAPK1)
   04620 Toll-like receptor signaling pathway
    105069349 (MAPK1)
   04621 NOD-like receptor signaling pathway
    105069349 (MAPK1)
   04625 C-type lectin receptor signaling pathway
    105069349 (MAPK1)
   04650 Natural killer cell mediated cytotoxicity
    105069349 (MAPK1)
   04660 T cell receptor signaling pathway
    105069349 (MAPK1)
   04658 Th1 and Th2 cell differentiation
    105069349 (MAPK1)
   04659 Th17 cell differentiation
    105069349 (MAPK1)
   04657 IL-17 signaling pathway
    105069349 (MAPK1)
   04662 B cell receptor signaling pathway
    105069349 (MAPK1)
   04664 Fc epsilon RI signaling pathway
    105069349 (MAPK1)
   04666 Fc gamma R-mediated phagocytosis
    105069349 (MAPK1)
   04062 Chemokine signaling pathway
    105069349 (MAPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105069349 (MAPK1)
   04929 GnRH secretion
    105069349 (MAPK1)
   04912 GnRH signaling pathway
    105069349 (MAPK1)
   04915 Estrogen signaling pathway
    105069349 (MAPK1)
   04914 Progesterone-mediated oocyte maturation
    105069349 (MAPK1)
   04917 Prolactin signaling pathway
    105069349 (MAPK1)
   04921 Oxytocin signaling pathway
    105069349 (MAPK1)
   04926 Relaxin signaling pathway
    105069349 (MAPK1)
   04935 Growth hormone synthesis, secretion and action
    105069349 (MAPK1)
   04919 Thyroid hormone signaling pathway
    105069349 (MAPK1)
   04928 Parathyroid hormone synthesis, secretion and action
    105069349 (MAPK1)
   04916 Melanogenesis
    105069349 (MAPK1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105069349 (MAPK1)
   04270 Vascular smooth muscle contraction
    105069349 (MAPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    105069349 (MAPK1)
  09156 Nervous system
   04724 Glutamatergic synapse
    105069349 (MAPK1)
   04725 Cholinergic synapse
    105069349 (MAPK1)
   04726 Serotonergic synapse
    105069349 (MAPK1)
   04720 Long-term potentiation
    105069349 (MAPK1)
   04730 Long-term depression
    105069349 (MAPK1)
   04723 Retrograde endocannabinoid signaling
    105069349 (MAPK1)
   04722 Neurotrophin signaling pathway
    105069349 (MAPK1)
  09158 Development and regeneration
   04360 Axon guidance
    105069349 (MAPK1)
   04380 Osteoclast differentiation
    105069349 (MAPK1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105069349 (MAPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105069349 (MAPK1)
   05206 MicroRNAs in cancer
    105069349 (MAPK1)
   05205 Proteoglycans in cancer
    105069349 (MAPK1)
   05207 Chemical carcinogenesis - receptor activation
    105069349 (MAPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    105069349 (MAPK1)
   05203 Viral carcinogenesis
    105069349 (MAPK1)
   05230 Central carbon metabolism in cancer
    105069349 (MAPK1)
   05231 Choline metabolism in cancer
    105069349 (MAPK1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105069349 (MAPK1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105069349 (MAPK1)
   05212 Pancreatic cancer
    105069349 (MAPK1)
   05225 Hepatocellular carcinoma
    105069349 (MAPK1)
   05226 Gastric cancer
    105069349 (MAPK1)
   05214 Glioma
    105069349 (MAPK1)
   05216 Thyroid cancer
    105069349 (MAPK1)
   05221 Acute myeloid leukemia
    105069349 (MAPK1)
   05220 Chronic myeloid leukemia
    105069349 (MAPK1)
   05218 Melanoma
    105069349 (MAPK1)
   05211 Renal cell carcinoma
    105069349 (MAPK1)
   05219 Bladder cancer
    105069349 (MAPK1)
   05215 Prostate cancer
    105069349 (MAPK1)
   05213 Endometrial cancer
    105069349 (MAPK1)
   05224 Breast cancer
    105069349 (MAPK1)
   05223 Non-small cell lung cancer
    105069349 (MAPK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105069349 (MAPK1)
   05170 Human immunodeficiency virus 1 infection
    105069349 (MAPK1)
   05161 Hepatitis B
    105069349 (MAPK1)
   05160 Hepatitis C
    105069349 (MAPK1)
   05171 Coronavirus disease - COVID-19
    105069349 (MAPK1)
   05164 Influenza A
    105069349 (MAPK1)
   05163 Human cytomegalovirus infection
    105069349 (MAPK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105069349 (MAPK1)
   05165 Human papillomavirus infection
    105069349 (MAPK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105069349 (MAPK1)
   05135 Yersinia infection
    105069349 (MAPK1)
   05133 Pertussis
    105069349 (MAPK1)
   05152 Tuberculosis
    105069349 (MAPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105069349 (MAPK1)
   05140 Leishmaniasis
    105069349 (MAPK1)
   05142 Chagas disease
    105069349 (MAPK1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105069349 (MAPK1)
   05020 Prion disease
    105069349 (MAPK1)
   05022 Pathways of neurodegeneration - multiple diseases
    105069349 (MAPK1)
  09165 Substance dependence
   05034 Alcoholism
    105069349 (MAPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105069349 (MAPK1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105069349 (MAPK1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105069349 (MAPK1)
   04934 Cushing syndrome
    105069349 (MAPK1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105069349 (MAPK1)
   01524 Platinum drug resistance
    105069349 (MAPK1)
   01522 Endocrine resistance
    105069349 (MAPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cbai01001]
    105069349 (MAPK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cbai03036]
    105069349 (MAPK1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cbai04147]
    105069349 (MAPK1)
Enzymes [BR:cbai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105069349 (MAPK1)
Protein kinases [BR:cbai01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105069349 (MAPK1)
Chromosome and associated proteins [BR:cbai03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     105069349 (MAPK1)
Exosome [BR:cbai04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   105069349 (MAPK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2 Choline_kinase Kinase-like Kdo
Other DBs
NCBI-GeneID: 105069349
NCBI-ProteinID: XP_010953765
UniProt: A0A9W3EQT6
LinkDB
Position
Unknown
AA seq 263 aa
MKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL
NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI
LAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNR
LFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDD
LPKEKLKELIFEETARFQPGYRS
NT seq 792 nt   +upstreamnt  +downstreamnt
atgaaggatgtatacatagtacaggacctcatggagacagatctctacaagctcttgaag
acacagcacctcagcaacgaccatatctgctattttctctaccagatcctcagagggctt
aaatatatccattcagctaatgtgctgcaccgtgacctcaagccttccaacctgctgctc
aacaccacctgcgatctcaagatctgtgactttggtttggcccgtgttgcggatccggac
catgaccacacagggttcctgacggagtacgtagccacgcgctggtaccgggctccggaa
attatgttaaattccaagggctacaccaagtccattgacatttggtctgtaggctgcatc
ctggcagagatgctgtccaacaggcccatcttcccggggaagcactatctcgaccagctg
aaccacattctgggtattctcggatccccgtcacaggaagacctgaactgtattataaat
ttaaaagctagaaactacttgctttctcttccacacaaaaataaggtgccgtggaacagg
ctgttcccaaatgctgactccaaagctctggatctactggacaagatgctgacattcaac
ccccacaagaggattgaagtggagcaggctctggctcacccgtacctggagcagtactat
gacccaagtgacgagcccatcgctgaagcaccgttcaagtttgacatggagttggatgat
ttgcccaaggaaaagctcaaagaactcatttttgaggagaccgctagattccagccagga
tacagatcttaa

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