KEGG   Camelus bactrianus (Bactrian camel): 105070011
Entry
105070011         CDS       T07534                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
cbai  Camelus bactrianus (Bactrian camel)
Pathway
cbai04010  MAPK signaling pathway
cbai04020  Calcium signaling pathway
cbai04022  cGMP-PKG signaling pathway
cbai04024  cAMP signaling pathway
cbai04260  Cardiac muscle contraction
cbai04261  Adrenergic signaling in cardiomyocytes
cbai04270  Vascular smooth muscle contraction
cbai04723  Retrograde endocannabinoid signaling
cbai04725  Cholinergic synapse
cbai04726  Serotonergic synapse
cbai04727  GABAergic synapse
cbai04911  Insulin secretion
cbai04912  GnRH signaling pathway
cbai04921  Oxytocin signaling pathway
cbai04924  Renin secretion
cbai04925  Aldosterone synthesis and secretion
cbai04927  Cortisol synthesis and secretion
cbai04929  GnRH secretion
cbai04934  Cushing syndrome
cbai04935  Growth hormone synthesis, secretion and action
cbai05010  Alzheimer disease
cbai05020  Prion disease
cbai05022  Pathways of neurodegeneration - multiple diseases
cbai05207  Chemical carcinogenesis - receptor activation
cbai05410  Hypertrophic cardiomyopathy
cbai05412  Arrhythmogenic right ventricular cardiomyopathy
cbai05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cbai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105070011 (CACNA1S)
   04020 Calcium signaling pathway
    105070011 (CACNA1S)
   04024 cAMP signaling pathway
    105070011 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    105070011 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105070011 (CACNA1S)
   04929 GnRH secretion
    105070011 (CACNA1S)
   04912 GnRH signaling pathway
    105070011 (CACNA1S)
   04921 Oxytocin signaling pathway
    105070011 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    105070011 (CACNA1S)
   04924 Renin secretion
    105070011 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    105070011 (CACNA1S)
   04927 Cortisol synthesis and secretion
    105070011 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    105070011 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    105070011 (CACNA1S)
   04270 Vascular smooth muscle contraction
    105070011 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    105070011 (CACNA1S)
   04725 Cholinergic synapse
    105070011 (CACNA1S)
   04726 Serotonergic synapse
    105070011 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    105070011 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    105070011 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105070011 (CACNA1S)
   05020 Prion disease
    105070011 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    105070011 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    105070011 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    105070011 (CACNA1S)
   05414 Dilated cardiomyopathy
    105070011 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105070011 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cbai04040]
    105070011 (CACNA1S)
Ion channels [BR:cbai04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   105070011 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 105070011
NCBI-ProteinID: XP_010954568
UniProt: A0A9W3GTK2
LinkDB
Position
Unknown
AA seq 1871 aa
MEPPSPQDEGLRKKQPKKPVPEVLPRPPRALFCLTLENPVRKACISVVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNIIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDVDDLKEGKLALDEGGSDTESLYEIAGLNKIIQFVRHWRQWNRI
FRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVANRVLLSLFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEVLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRFDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGILAYGGPTYPGVLVSIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSKGLPDKSEEEKTTLTKKLDQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEVPISPRPRPLAELQLKEKAVPIPDASAFF
IFSPTNRIRILCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDV
SKMTEEECRGYYYVYKDGDPTQVELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPELL
YKAIDANEEDKGPVYNHRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTVIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTSFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLMAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPH
VMANQRPLQFTEIEMEELESPVFLEDFPQHPSTNPLARANTNNANANATGGNSNHGNRWA
FSSVHYEGEFPGETETPAARGGAFGQHWGTLGPHSKSCVERLKGPRTQRAVPGAQAPPTP
CQAWVESPVAEERSPTPESLPKEAPPGNRTEDRTPRCPAPATALLIREALVRGGLDTLAT
DANFVKATGQALAEACQMEPEEVEVAAAELLKGREAPEGVASAPGRLGLGSSLGSLDQLQ
GSQETLIPRRL
NT seq 5616 nt   +upstreamnt  +downstreamnt
atggagccaccctcgccccaggatgagggcctgaggaagaaacagcccaagaagcctgtt
cccgaggtcctgcccaggccgccccgggccttgttctgtctgaccctcgagaaccccgtg
aggaaagcctgcatcagcgtcgtggagtggaaacccttcgagaccatcatcttactcacc
atctttgccaactgtgtggcgctggccgtgtacctgcccatgccggaggatgacaacaac
actctgaacctcggcctggagaagctggagtacttcttcctcatcgtcttctccatcgag
gccgccatgaagatcatcgcttacggcttcctgttccaccaggacgcctacctgcgcagc
ggctggaacgtgctggacttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caggttaacattatccagagcaacacggccccgatgagcagcaagggagccggcctggat
gtcaaggcgctgagagccttccgcgtgctcaggcccctgcggctggtgtccggggtgcca
agcctgcaggtggtcctcaactccatcttcaaggccatgctacccctgttccacatcgcc
ctgctggtcctcttcatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgctacttcatcgggacggacatcgtggccacggtggagaatgag
aagccgtcgccctgcgcccggacgggctcaggccgcccctgcaccatcaacggcagcgag
tgccggggcggctggccgggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcactgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaacgacgccatcgggaacgagtggccctggatctactttgtcaccctcattctgctg
ggctccttcttcattctcaacctggtgctgggcgtcctgagtggggagttcaccaaggaa
cgggagaaggccaagtccaggggaaccttccagaagctgcgggagaagcagcagctggag
gaggacctccggggctacctgagctggatcacacagggcgaggtcatggacgtggacgac
ttgaaagaagggaagctggctttggatgaaggcggctcagacacggagagcttgtacgaa
atcgcgggcttgaacaaaatcatccagtttgtccgtcactggaggcagtggaaccgcatc
ttccgctggaagtgccacgacgtggtgaagtccagggtcttctactggctggtcatcttg
atcgttgccctcaacaccctgtccatcgcctccgagcaccaccaccagcctctctggttg
acccacttgcaagacgtggccaaccgcgtgctgctgtccctgttcacggtggagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggaggtcctgctggtggagtcgggcgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctcctccggatcttcaagatcaccaag
tactggacgtccctgagcaacctggtggcctccctgctcaactccatccgctccatcgcc
tccctgctgctgctgctcttcctcttcatcgtcatcttcgccctgctgggcatgcagctc
tttgggggcaggttcgacttcgaggacaccgaggtgcggcgcagcaacttcgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctgacgggcgaggactggaactccgtgatg
tacaacgggatcctggcctacggcgggccgacctaccccggggtgctcgtgtccatctac
ttcatcatcctgttcgtctgcggcaactacatcctgctcaacgtcttcctggccatcgcc
gtggacaacctggcggaggcggagagcctgacttctgcccagaaggccaaggccgaggag
cggaggcgcaggaagatgtccaaggggctcccggacaagtcagaggaggagaagacaacg
ttgaccaagaagctggaccagaaacccaagggggagggcatccccaccacagccaagctg
aagatcgacgagtttgagtccaacgtcaatgaggtgaaggacccctacccctcggccgac
ttcccaggggatgatgaagaagatgagcccgaggtcccaattagcccccggccacgtccg
ctggccgagctgcagctgaaggagaaggccgtgcccatcccagatgccagcgccttcttc
atcttcagccccaccaacaggatccgtatcctctgtcaccgcattgtcaacgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgcagcgctggctgctgaggac
cccatcagggctgagtccgtgaggaatcagatccttgggtattttgatatcgcatttacc
tctgtcttcactgtggagattgtcctcaagatgaccacctacggggccttcctgcacaag
ggctccttctgccgcaactacttcaacatgctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcaccatctctgtggtgaaaatcctgagggtactgaga
gtgctccgaccactccgggccatcaacagagccaaagggctgaagcacgtggtgcagtgc
gtgtttgtggccatccgcaccatcgggaacatcgtcctggtcaccacgctgctccagttc
atgttcgcctgcatcggtgtccagctcttcaaggggaagttcttcagctgcaatgacgtg
tccaagatgacagaggaggagtgcaggggctactactacgtgtacaaggatggggacccc
acgcaggtggagttgcgtccccgccagtggatacacaacgacttccacttcgacaacgtg
ctctcggccatgatgtcactcttcacggtgtccaccttcgagggatggccggagctgctg
tacaaggccattgatgctaacgaggaggacaagggccccgtgtacaaccaccgcgtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttc
gtgggctttgtcatcgtcaccttccaggagcagggggagacggagtacaagaactgcgag
ctggacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccgccccctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtacgtcgtcacctcctcctacttc
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagagcagatgaaccacatctcagacatcctcaacgtggccttcaccgtcatc
ttcaccctggagatgatcctcaagctcatggcgttcaaggccaggggatactttggggac
ccctggaacgtgtttgacttcctgattgtcatcggcagcatcatcgacgtcattctcagc
gagatcgacactttcctggcctccagcgggggactgtattgcctgggtggcggctgcggg
aacgttgaccccgacgagagcgcccgcatctccagcgcctttttccgcctgttccgcgtc
atgaggctgatcaagctgctgagccgtgcggagggcgtgcgcacgttgctctggaccttc
atcaagtccttccaggccctgccctacgtggctctgctcatcgtcatgctctttttcatc
tacgctgtcatcggcatgcagatgtttgggaagatcgccatggtggacgggacccagatc
aaccgaaacaacaacttccagaccttcccccaggctgtgctgctgctcttcaggtgcgcc
acgggcgaggcgtggcaggagatcctgctggcctgcagctacggcaagctgtgcgacccc
gagtcggactacgcccccggggaggagcacacgtgcggcaccagcttcgcctactactac
ttcatcagcttctacatgctgtgcgccttcctgatcatcaacctctttgtggccgtcatc
atggacaactttgactacctcacgcgggactggtccatcctgggtccccaccacctggac
gagttcaaggccatctgggcagagtatgacccggaggctaagggcagaatcaaacatctg
gatgtggtgaccctgctgagaaggatccagccccctctgggctttgggaagttctgccca
caccgggtggcatgtaagcggctggtgggcatgaacatgcccctgaacagcgatggtacg
gtcaccttcaatgccaccctcttcgctctggtccgcacagcgctcaagatcaagacggaa
ggtaacttcgagcaggccaacgaggagctgcgggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcatccctccaataggagatgatgaggtgacggtg
gggaagttctacgccacgtttctcatccaggagcacttccgaaagttcatgaagcgccag
gaggagtattatgggtatcggcccaagaaggacactgtgcagatccaggccgggctgcgg
accattgaggaagaggcagcccctgagatccgccgcaccatctcaggggacctgatggct
gaggaggagctggagagagccatggtggaggccgcgatggaggaagggatattccggagg
accggaggtctgttcggccaggtggacaacttcctggaaaggaccaactccctgccccac
gtcatggccaaccagaggcccctccagttcactgaaatagagatggaggagctggaatcg
cctgtcttcttggaggacttccctcagcatccaagcaccaaccccctggctcgagccaac
accaacaatgccaatgccaacgccacgggtggcaacagcaaccatggcaaccgctgggcg
ttctccagtgtccactacgagggggagttcccgggagagacagagacacctgccgccagg
ggaggagcctttggccagcactgggggaccctgggcccccacagcaaatcctgtgtggaa
aggctgaagggacctcggacccagagagctgtgcccggagcgcaggcacctcccacccct
tgccaggcgtgggtggagtctcccgtggctgaggagaggagccccacaccagagtccctg
cccaaggaggcaccgcctggcaataggactgaggaccgcacccccaggtgcccagctcca
gccacagccctgctgatccgagaggctctggttcgagggggcctggacaccctggcaact
gatgctaactttgtcaaggcgacaggccaggccctggccgaggcctgccagatggaacca
gaggaggtggaggtggcagcagcagagcttctgaaggggcgtgaggccccagagggcgtg
gccagcgccccggggcgcttgggcctcgggtcctccctgggcagcctcgaccagcttcag
ggctcccaggagacccttattccccgcaggctgtga

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