Camelus bactrianus (Bactrian camel): 105070227
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Entry
105070227 CDS
T07534
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
cbai
Camelus bactrianus (Bactrian camel)
Pathway
cbai00230
Purine metabolism
cbai00670
One carbon pool by folate
cbai01100
Metabolic pathways
cbai01523
Antifolate resistance
Module
cbai_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cbai00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105070227 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105070227 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105070227 (GART)
Enzymes [BR:
cbai01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
105070227 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
105070227 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
105070227 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
Sacchrp_dh_NADP
RimK
Motif
Other DBs
NCBI-GeneID:
105070227
NCBI-ProteinID:
XP_010954853
UniProt:
A0A9W3GTS1
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHALAWKLAQSNHVKQVLVTPGNAGTACSEKISNTDVSISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVDNMTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKPEEACTFITSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMHDKAF
GEAGETVVIEELLEGEEVSCLCFTDGRTVDPMPPAQDHKRLLEGDHGPNTGGMGACCPAP
QVSKDLLLKIKNTILQRTVDGMQQEGVPYTGILYAGIMLTNNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPIWLDSHTAVTVVMASKGYPGDYTKGVEITGFSEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLVSALEEAKKGLAAIKFEGAIYRKD
IGCHAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFNDPLLACGTDGVGTKLKIAQQCHKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVTGIAEACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPSGCGDQTLGDLLLIPTR
IYSHLLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVELDAQTWKIPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLTKQILQDLQQHEEEAWVIGRVVVCPEGSPRVKVKH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPRSSAHIVVV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKSREAFDTAVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDSGVTLTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKIFPSALQLVASGTVQLGDNGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcagtggaggaagggaacatgcactggcctggaaa
cttgcacagtccaatcatgtcaaacaggtgttggttaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatactgatgtctcaatcagtgatcacactgcccttgctcaa
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgttgataacatgacatctgcaggagtgcgatgctttggccccacagcagaagca
gctcagttagagtccagcaaaagatttgccaaagaatttatggaccgacatggaatccca
actgcacgatggagagctttcaccaaacctgaagaggcctgtaccttcattacgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaggagatcatgcatgataaagctttt
ggagaagctggagaaacagttgttattgaagaacttcttgaaggagaagaggtttcttgt
ctgtgtttcactgatggaaggactgtggaccccatgcccccagcacaggaccataagcga
ctgctggagggagatcatggccccaacactgggggaatgggagcttgttgtccagcacct
caggtttctaaggatctgttgctaaaaattaaaaataccattcttcagaggactgtggat
ggcatgcagcaggagggtgtgccatacacaggtattctttatgctggtataatgctgacc
aacaatggcccaaaagttctggagtttaattgtcgtttcggagatccagagtgccaggtg
atcctcccacttcttaaaagcgatctttatgaagtgattcagtctaccttagatggcctg
ctctgcacctctcttcctatttggcttgacagccacactgctgtaactgttgtcatggcg
agtaaaggttatccaggagactacaccaagggtgtagagataacaggattttctgaggct
caagctttaggactagaggtgttccaagcaggcactgccctaaaagatggcaaagtggtg
actaatgggggtagggtccttactgtaacagccatccgggaaaatcttgtctcagccctt
gaagaagccaagaaaggactagctgctataaagtttgagggagccatttacaggaaggac
atcggctgtcatgccatagctttccttcagcagcccagaggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaagcctttagcaaaagcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagccggttttaatgatcctcttctggcctgtggaacagacggcgttggaactaaactg
aagattgcgcagcagtgccataaacacgataccattggtcaagatttggttgcaatgtgt
gtaaatgatattctggcacaaggagcagaacccctcttttttcttgattatttttcctgt
ggaaaacttgacctcaatacaactgaagctgttgtcactggaattgctgaagcttgtaaa
aaagctggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatgtacccacct
ggagagtatgacctagccggttttgccgttggtgccatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggacgttgttattggaatagcttcctctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcgaaatcttccctccagtactcctct
ccagcaccctctggctgtggtgaccagaccttaggggacttacttctaattccaactaga
atctacagccatttgctgctacctgtcctacgttcaggacatgttaaggcttttgcccat
attactggtggaggcttgctagaaaacatccccagagtcctccctcagaaatttggggtg
gagttagacgcccagacctggaagatccccaggatcttctcatggttacagcaggaagga
cacctctctgaagaagagatggccagaacatttaactgtgggatcggggctgccctcgtg
gtatctaaggatctgacaaagcagattctgcaggatcttcagcagcacgaggaagaggcc
tgggtgattggcagggtggttgtatgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcaaataaatggatcagtactggagaatggcaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagttgctgtcttaatatccggaacaggatcgaac
cttcaagctctcatagacagtactagggagccaaggagctctgcacacattgttgttgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccggaattcccacc
agggtaattaatcataaattatataaaagtcgtgaagcatttgacactgcagttgaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgcttaacatccacccatccttgcttcct
tcgtttaagggttcaaatgcccatgaacaagtcctggactccggagtcacactcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttccagtgaagaggggagacactgttgcaactctatctgaaagagtaaaattagcagaa
cataaaatattcccctcagccctccagctggtggccagtggaactgtgcagcttggagac
aatggcaagatctgttgggtcaaagaggaatga
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