Camelus bactrianus (Bactrian camel): 105071130 Help Entry 105071130         CDS       T07534                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism cbai  Camelus bactrianus (Bactrian camel) Pathway cbai05165   Human papillomavirus infection cbai05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:cbai00001]  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     105071130 (UBR4)   09172 Infectious disease: viral    05165 Human papillomavirus infection     105071130 (UBR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:cbai04121]     105071130 (UBR4) Enzymes [BR:cbai01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      105071130 (UBR4) Ubiquitin system [BR:cbai04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     105071130 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  105071130 NCBI-ProteinID:  XP_010956065 LinkDB All DBs Position Unknown AA seq 5207 aa AA seqDB search MATSGGEEAAAAAPAPGVPATGSDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESE SEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDE ACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPV SPELRQKEVQMNFVNQLTSVFNPRTVASSPVGPQAPAEGESDEQSSTDQASAIKTKNVFI AQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFH SLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAILHVGSAQQVRT GSTSSKEEDYESDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFL ILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHA VKLLTSLFQDLQVEALHKGWEADGPPAVLSIMAQSTSIQRIQRLIDSVPLTNLLLTLLST SYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETIS PSKEKVAPPPPPPPPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITS SMLNSRNNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGSSDEEFAAALYHFNHSLVTS DLQSPNLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKAGAQGDPDVPECL KVWDRFLSTMKQNALQGVVPNETEDLNVEHLQLLLLIFHNFSEKGRRDILTLFVQIIQEL SANTDAQMRSVPLILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDSGS RRATAPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKL VKYDELYTALTSLLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYM NQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHAGSLLELASSKCS SVKYDVEIVEEYFARQISSFCNIDCTTILQLHEIPSLQSIYTLDAAISKVQVSLDEHFSK MAAETDPHKSSEITKNLLPATLQLIDTYASFTRCDGLPAQRCRKSGILVLRWFTFFRRLK IPWIELGSLSTVHSGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQAVC ESWNNINTNEFPNIGSWRNAFANDTIPSESYISAVQAAHLGTLCGQSLPLAASLKHTLLS LVRLTGDLIVWSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERILGPAESDEFLARV YEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEEFFSDSGELVQI MMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLCGSLAQLACVEPVRLQAWLTR MTASPPKDSDQLDVIQENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLIPMATEMLANGD GTGFPELMVVMATLASAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHV VVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEEREELAVEEEDSQAEDSDEDSLCN KLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAK EDGSCLALVKRTPSSGMSSTMKESAFQSEPRVSESLVRHTSASPADKAKVTISDGKVADE EKPKKSSLCRTVEGCREELQNQANFSFAPLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQ ALRELHTVDKVVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMC VLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGN PCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTA DFVKIYDLSVDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASS AQQGPFYVTNVLEINHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGRSFAATISRTT LEVLQLFPINIKSSNGGSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQ EIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPALQPS SVISIMKPVRKRKTATITTRTSSQVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHR LNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLS RSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEF PSASVSNICPSNLNQSNGTGDGDSAAPATTSGTVLERLVVSSLEALESCFAVGPIIEKER NKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSK EGKDLDPEVFQRLVITARSIAIMRPNNLVHFTESKLPQMETEGADEGREPQKQLEGDCCS FITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASK IYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEK MQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGF PPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSD TTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGD ATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGEGEGDVHASNRLHMVRLMLLER LLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVS KKNERSALNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLH VLKSLLEYWKSQQNEEEPMATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLL TEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGS KEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACA EIAAQRTINWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASA GSSSASSSSAPVATSSGQATTQSKSSTKKSKKEEKEKEKEGESSGSQEDQLCTALVNQLN KFADKETLVQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELPA YGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLV EFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGD LKRTKMVRTVNLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNL MIEFADFYENYQASTETLQCPRCSASVPASPGVCGNCGENVYQCHKCRSINYDEKDPFLC NACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSSINTLLDKADRVYHQLMGHRPQL ESLLCKVNEAAPEKPQDDSGTAGGISSTSANVNRYILQLAQEYCGDCKNSFDELSKIIQK VFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVT EHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGSAAMREEVRQLMCLLTRDNPEAT QQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMA VNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNEIHAQAQLWL KRDPKASYEAWKKCLPIRGIEGNGKSPSKSELRHLYLTEKYVWRWKQFLSRRGKRTSPLD LKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECA AEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKS LTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTT GTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQE DFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLP VAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMA QCGGLECMLNRLAGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTL NLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQ INSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFNLLWSSLLFPPRYDEDHSGDDK VFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKNLDADIWKKFLSR PALPFILRLLRGLAIQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPD VNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGL TCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVR LARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQL NIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIVHTVLYVLNTTRATSREEKNFQA FLEQPKEKWVESAFEVDGPHYFTVLALHILPPEKWRATRVEILRRLLVTSQARAVAPGGA TRLTDKAVKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIHE AADKALKAFQEEFMPVETFSEFLDAAGLLSEITDPESFLKDLLNSVP NT seq 15624 nt NT seq  +upstreamnt  +downstreamnt atggcgacgagcggcggcgaagaggcggcggctgcggcgccggcgcccggggtcccggca acggggtcagacacgaccccgggctgggaggtggctgtgcggcccctgctatccgcgtcc tattccgccttcgagatgaaggagttgccgcagctggtggcctcagtcatcgagagtgaa tcagaaatcctgcaccatgagaagcagtacgagccattctactcatctttcgttgcactt tccacgcactatattacaacagtttgtagccttattccccggaaccaacttcagtcggtg gcagcagcctgtaaagtcctgattgagttttctctcttacgtctggagaatccagatgag gcttgtgctgtgtcccagaaacacttgattctcctcatcaagggcctttgcactggctgt agccgactggacagaactgaaattatcacgtttacagcaatgatgaaatcggccaagctg ccacagacagtgaagacgctctcagatgtggaagatcagaaagagctggcctcaccagta agcccagagctgaggcagaaggaggtccagatgaattttgtgaaccagctgacatcagtt ttcaaccctaggactgtagcatcatcgcccgtaggtccacaggctccagcggaaggagaa agtgatgagcagtcatccacagatcaggcctctgctatcaaaaccaagaatgtgttcata gctcagaatgtggctagtcttcaggagcttggtggctccgagaagctactgcgcgtgtgt ttgaacctgccgtatttcctccgctacatcaatcggtttcaagatgcagtgttagccaat tccttcttcatcatgcctgcaacagtagcagatgccactgctgttcgtaatggttttcat tcactggtgatcgatgtaaccatggcattggataccctttctctacctgtgctggaacct ctcaatccttctcgtctgcaggatgtgacagtcctcagcctaagctgtttgtatgcaggt gtgagtgtggcaacttgcatggccatccttcatgtgggtagtgcccagcaagtgcggaca gggtccacgagctccaaagaagaagactatgagagtgatgcagctacgattgtccagaaa tgtcttgaaatctatgacatgattggacaagcaattagcagttcccgccgggctggtggt gagcactatcagaacttccaattgctgggtgcctggtgtttgttaaatagccttttcctc atattgaacctcagtcctactgccttggctgataaggggaaagagaaagatccgctggcc gcacttcgagtgagagacatcctttctcgtacaaaagagggagtgggctctccgaaactg gggcctggaaaagggcatcaggggtttggggtgctctcagtaatactggcaaaccatgct gtcaagctgttaacatctctctttcaagacctgcaagtggaggctctgcacaagggttgg gaggcagatggtccgcctgcagtcctgagcattatggctcagagcacctccatacagagg attcagcggctgattgactctgtcccactgacgaacctgctgttgacattactctcaact tcctacagaaaggcatgtgtcctgcagcgtcagaggaagggctccatgagcagcgatgcc agcgcctctactgactcaaacacctactacgaggatgatttcagcagcacggaggaggac agcagccaagatgatgacagtgagcctattctggggcaatggtttgaagagaccatctcc cccagtaaagagaaagtggcacctccgcctcctcccccaccccctccgctggaaagctca cctcgagttaagagcccgagtaagcaggcccctggtgagaaaggcaacattctggctagc cgcaaagatcctgagttgttcttaggtctggcttccaacattttgaacttcatcacctct tccatgctgaactctcgaaacaattttatccgaaactatctgagtgtatctctttcagag caccatatggccaccctggccagtatcattaaggaggtggacaaagatggactgaagggt tcatcagatgaagagtttgctgctgctctctatcacttcaaccactctctggtgacttct gaccttcagtcccctaacctgcagaacacactgttgcagcagctgggagttgctcctttt tccgagggcccttggcccctgtacattcaccctcagagcctctctgtgctttcgcgcctc ttgctcatctggcaacacaaagctggtgctcaaggtgacccggacgtccctgaatgcctt aaagtttgggacaggtttttgtcgacaatgaagcagaatgccctgcaaggggtggtgccc aatgagacagaagatttgaatgtagaacacctgcagctgctccttctcattttccacaac ttcagtgagaaaggccggcgggacatattgaccctttttgtgcagatcatccaggaatta agcgccaacacggatgcccagatgcgctctgtgcctctcatcctggctcgcctccttttg atctttgattatctgcttcatcagtactcaaaagcccctgtgtatctgtttgagcaggtg cagcataacttgcttagtcctccttttgggtgggcaagcggatctcaggacagcggcagc cgccgggcgaccgcgcctctctatcatgggttcaaagaagtggaagagaactggtctaag catttttcatcagatgcagtcccacaacccagattctactgtgtcctgtccccagaagcc tcagaggatgatttgaaccgactcgattctgtggcatgtgatgttcttttctccaagctt gtcaagtatgatgagctctacacagcactgacatccctgcttgcagctgggtcccagctt gatacagtcaggagaaaggaaaacaagaatgtaacagccctggaggcctgtgcccttcaa tattacttcttgatactgtggaggatcctagggattttgccaccatcaaagacttacatg aaccagctggccatgaactcgccagagatgagtgaatgtgacatcctacacactctgcgg tggtcttcccgcctccggatcagctcctacgtcaactggataaaggaccaccttatcaaa cagggaatgaaggctgaacatgctggttctctcctagaactggcatccagcaagtgcagc tcagtgaaatatgatgtggaaattgtagaggaatactttgctcgacagatctcgtcattc tgtaacatcgactgtaccaccatcttgcaactccatgaaattcctagcctgcagtccatc tacacactcgatgctgcgatctcgaaggtccaggtctctttggatgagcatttctccaag atggctgccgagaccgatcctcataagtcatctgagatcaccaagaacctgctcccagcc acgctgcagctcattgacacctacgcgtcgttcactaggtgtgacgggctgcctgcccag agatgtcggaaatcgggaattttggtgcttaggtggtttactttctttaggcgcctgaaa attccttggattgaacttggtagtttgagtactgttcactctggatccactgaaaaacct tcccaggagaaattacatggctttgctgctgttttggctattggctctagcaggtgcaag gcaaacacactgggtccaaccctggttcagaatttaccatcatcggtacaggctgtgtgt gagtcctggaacaacatcaacaccaatgagtttcccaacattggatcctggcgtaatgcc tttgccaacgacaccatcccttctgagagttacatcagtgctgtgcaggccgctcacctg gggactctttgtggccagagcctgcccctggcggcctccctgaagcacacactcctgtcg ctggtcaggctgactggagatctgattgtttggtccgatgagatgaacccgccacaggta attcggaccctgctcccccttcttctggagtcgagcactgaaagtgttgctgagatcagt agcaactccctggagcgcatcctgggccctgcagagtctgatgagttcttggcccgcgtt tacgagaagctcatcactggttgttacaacattctggctaatcatgcagatcccaatagt ggactggatgaatccatcttagaggaatgtctccagtatttggaaaaacaactggaaagc agccaggctcgtaaagctatggaggaatttttctctgacagtggagaacttgtgcagatc atgatggcaacagccaatgagaacctctctgctaaattctgtaaccgagttttgaaattc ttcaccaaactcttccagctgactgagaagagccctaacccgagccttctgcatctctgt ggctctctggctcagctggcttgtgtggagcctgtgcgtctccaggcctggctcacccgc atgactgcatcgccccccaaagattctgaccagctagacgtgatccaggagaacaggcag ctgctgcagttactgactacgtacattgtccgggaaaacagccaagttggggaaggtgtg tgcgctgtgcttttgggtaccctgatccccatggcaacagagatgctggccaacggtgat gggactggtttccctgaactcatggttgtgatggctaccctggccagcgcaggtcaaggt gctggccatcttcagcttcataatgctgctgtggactggctgagtagatgcaagaaatac ctgtcacagaagaatgtggttgaaaagctgaatgccaatgtaatgcatggaaagcatgtg gtagtcctcgagtgcacatgccatattatgtcttacttggctgatgtcaccaatgccctg agccagagtaatggtcaaggcccaagtcacctctcggtggacggggaagagcgagaggag ttggcagtggaagaggaagactcccaggcggaggattcagatgaagattctctttgcaat aagctctgcacttttaccatcactcagaaagaattcatgaaccagcactggtaccactgt cacacctgcaaaatggttgatggggtgggtgtgtgcacagtatgtgccaaggtgtgccac aaagatcacgagatttcctatgccaagtatgggtccttcttttgtgactgtggagccaag gaagacggcagctgtttggctctggtgaagcgaactcccagcagtggcatgagctccacc atgaaggagtcggcatttcagagtgaacccagggtctcagagagtctcgtgcgccacacc agcgcctccccggctgacaaggccaaagtcaccatcagcgacgggaaggttgccgatgaa gagaagcccaagaagagcagcctgtgccgcacagtagagggctgccgggaggagctgcag aaccaggccaatttctccttcgctcctctcgtgttagacatgctcaatttcctcatggat gccattcagaccaactttcagcaggcttcagctgtggggagcagcagccgggctcagcaa gccctccgtgagctgcatacagtggataaggtggttgagatgacagaccagctgatggtt cccaccttaggctcccaggaaggtgcctttgagaatgttcggatgaattacagcggagac cagggccagactattcgacagctaatcagcgcccacgtgctcaggagggtggctatgtgt gtgctctcctcccctcatgggcgccgccagcatttggctgtcagccatgagaaaggaaag atcactgttctgcagctctcggcactcctgaaacaagcagattctagcaaaagaaagttg actctgacccgcctggcttctgccccggtccccttcactgtactgagcctcactgggaat ccatgcaaggaggactaccttgctgtttgtgggctgaaggactgccacgtgctgaccttc agtagctcaggctctgtttcggatcacttggttttgcacccccagttggcaacagggaac ttcatcatcaaagcagtgtggttacctggttcacagaccgagttagcgattgtcactgca gactttgtcaagatttatgacctgtctgttgatgccttgagtccaaccttctactttctc ctgcctagctcaaagataagagatgttaccttcctcttcaatgaagagggaaagaacatc attgttataatgtcttcggctgggtacatctatactcagctcatggaagaggccagcagt gcccagcagggacccttctatgtcactaatgtgctggaaatcaaccacgaggacctgaag gacagcaacagccaggtggcgggtggtggtgtgtccgtctactactcccacgtgttgcag atgctcttcttcagctactgtcaaggcagatcgtttgcagccaccatcagtaggacaact ctggaggtgttgcagctcttccccatcaacatcaaaagttccaatggcggcagtaagacg tctcctgccctttgccagtggtctgaggtgatgaaccaccctggcctggtgtgttgtgtc cagcagactacaggcgtgccgctggtggttatggtgaaaccggacacttttctcatccag gagattaagactcttcctgctaaggcgaagatccaggacatggtcgccatcaggcacacg gcctgcaacgaacagcagcggacgacgatgatcttgctgtgcgaggacggcagcctgcgc atttacatggccaacgtggagaacacctcctactggctgcagccggccctgcagcccagc agcgtcatcagcataatgaagcctgttcgaaagcgcaaaacggctaccatcacaacccgc acgtctagccaggtgaccttccccattgacttctttgaacacaaccagcagctgacagat gtggagtttggtggtaatgacctcctgcaagtctacaacgcacagcagataaagcaccgg ctgaattccactggcatgtatgtggccaacaccaagcctggtggcttcaccattgagatt agtaacaacaacagtactatggtgatgacaggcatgcggatccagattgggacccaggcc attgaacgggccccatcgtacattgagatcttcggcagaactatgcagcttaacctgagt cgctcacgctggtttgacttccccttcaccagagaagaagctctgcaggctgacaagaag ctgaacctcttcattggggcctcggtggatccagcaggtgtcactatgattgatgctgta aaaatttatggcaagactaaggagcagtttggctggcccgatgagcccccggaagaattc ccttctgcctccgtcagcaacatctgtccttcaaacctgaaccagagcaatggcactgga gacggtgactcagctgcccctgccaccacgagtggaactgtcctggagaggctggttgtg agttctttagaagccctggaaagctgctttgctgttgggccaatcatcgagaaggagaga aacaagaatgcagctcaggagctggccactttgctgctgtccctgccagcccctgccagt gtccagcagcagtccaagagccttctggccagcctgcacaccagccgctcagcctatcac agtcacaaggatcaggccttgctgagcaaagctgtgcagtgtctcaacacatccagcaaa gaaggcaaggatttggaccctgaggtcttccagaggctggtgatcacagctcgctccatt gccatcatgcgccctaacaaccttgtccattttacggagtcaaagctgccccagatggaa acagaaggagcggatgaggggagagaacctcagaagcagctggaaggagattgctgtagt ttcattacccagctggtgaaccacttctggaaactccatgcatccaaacccaagaatgcc ttcttggcacctgcctgcctgccaggcctaactcatattgaagctaccgtcaatgctctg gtggacattatccatggctactgcacctgtgagctggactgtattaatacagcatccaag atctacatgcagatgctgttgtgtcctgatcctgctgtgagcttctcgtgtaaacaagct ctaattcgagtcctaaggcccaggaataagcggagacacgtgacattgccctcctcccct cgaagcaacactccaatgggagacaaggatgatgatgacgatgatgatgcagatgagaaa atgcagtcatcagggatcccgaatggtggtcacatccgtcaggaaagccaggaacagagt gaggtggaccatggagattttgagatggtgtctgagtcgatggtcctggagacagctgaa aatgtcaacaatggcaacccctctcccctggaggccctgctggcaggcgcagagggcttc ccccccatgctggacatcccgcctgatgcagatgacgagaccatggttgaactagccatt gccctgagcctgcagcaggaccagcaaggcagcagcagcagtgccctgggcctgcagagc ctggggctgtccggccaggcacccagctcttcctctctggacgcaggaaccctctctgac accacagcatcagctccagcctcggacgatgagggcagcacagcagcgactgacggctcc acccttcggacttctcctgctgaccacggtgggagcgtgggctcggagagcgggggaagt gcagtggactcagtggctggcgagcacagtgtatctggccggagcagtgcttatggtgat gccacagcagaggggcatccggctggaccaggaagtgtcagctcaagcactggcgccatc agcaccaccaccggacatcaggaaggagatggctccgagggagaaggagaaggggaagga gaaggagatgtccacgctagcaacaggctgcacatggttcgtctgatgctgttggagaga ctactgcaaaccttgccccagttacgaaatgttggaggtgtccgggccatcccatacatg caggtaattctgatgcttactacagatctggatggagaagatgaaaaagacaagggggcc ctggacaacctgctctcccagctaattgctgaactgggcatggataaaaaggacgtctcc aagaagaacgagcgcagtgccctgaatgaggtccacctggtagtgatgaggctcctgagt gtcttcatgtccaggaccaaatccgggtccaagtcttccatatgtgagtcatcttccctc atctccagtgccacggcggcagccctgctgagctctggggctgtggactactgcctgcac gtgctcaagtccctgctggagtactggaagagccaacagaatgaggaggagcccatggcg accagccagttgctaaaaccacatactacttcatccccacccgacatgagcccgttcttc ctccgccagtatgtgaagggccatgctgctgatgtgtttgaggcctacactcagcttcta acagagatggtcctgaggctgccataccaaatcaaaaagatcgctgacactaattctcga atcccgcctcctgtctttgatcattcgtggttttactttctctcagagtacctgatgatc cagcaaactccgtttgtgcgccgccaagtccgcaaacttctgcttttcatctgtgggtca aaggagaaataccgccagctgcgggatttgcacacgctggactcccacgtgcgtgggatc aagaagctgctggaggagcaggggatattcctccgggcaagcgtggtcacagccagctca ggctccgccttgcagtatgacacgctcatcagcctgatggagcacctgaaagcctgtgca gagatcgctgcccagcgaaccatcaactggcagaagttctgcatcaaggacgactccgtc ctgtacttcctcctccaagtcagcttcctggtggacgagggggtgtctccggtgctgctg cagctgctctcctgcgctctgtgtggcagcaaggtgcttgctgctctggcggcttccgcg gggtcctccagtgcttcgtcctcctcggcccctgtggccaccagttctggacaagccaca acacagtcgaagtcatccacaaagaagagcaagaaagaagaaaaggaaaaggagaaagag ggtgagagctcaggcagccaggaggaccaactgtgcacagctctggtgaaccaactgaac aagtttgcagataaggaaaccttggtccagtttctgcgttgcttcctcttagagtccaat tcttcctcagtgcgctggcaagcccactgcctgacactgcatatctacagaaactctagc aaatctcaacaggagctcctgctagatctgatgtggtccatatggccagaactccctgcc tacggtcgtaaggctgcccagtttgtggacctactaggatatttctccttgaaaacccca caaacagagaagaagttgaaagaatattcacagaaggctgttgagattctgcggactcaa aaccatattcttaccaaccatcccaactccaacatttacaacaccttgtctggcttagtg gaatttgatggctattacctggagagtgacccctgcctggtgtgtaataatccagaagtg ccgttttgttacatcaagctgtcttccattaaagtggacacgcggtacaccaccacccag caggttgtgaagctcattggcagccacaccatcagcaaagtgacggtgaaaatcggggac ctgaaacggaccaagatggtgcggactgtcaacctctattacaacaaccgaactgtgcag gccatcgtggagctgaaaaacaagccggctcgctggcacaaagccaagaaggttcagctg acccctgggcagacggaggtgaaaattgacctgcctttgcccattgtggcctccaacctg atgattgagtttgcagacttctatgaaaactaccaggcctccacggagaccctgcagtgc ccacgctgtagtgcttctgtccctgccagcccaggggtctgcggcaactgtggggagaac gtctaccagtgtcacaagtgcagatccatcaactatgatgaaaaggatcccttcctgtgc aacgcctgcggcttctgtaaatatgctcgcttcgacttcatgctctatgccaagccttgc tgtgcagtggatcccattgagaatgaggaggaccggaagaaggcggtttccagcatcaac acgcttctggacaaagccgatcgagtgtatcatcagctgatgggacatcgcccacagctg gagagcctgctctgcaaagtgaacgaggcagcgcctgaaaagcctcaggatgactcggga acggctgggggcatcagctccacctcagcgaatgtgaatcgttacatcctgcagttggcg caggagtactgtggagactgcaagaactctttcgatgaactctccaaaatcatccagaaa gtttttgcttcacgcaaagagttgttggaatatgacctgcagcagagggaagcggccact aaatcatcccggacctccgtgcagcccacctttaccgccagccagtaccgcgccttatcc gttctcggctgtggccacacatcctccaccaagtgctacggctgcgcctcggccgtcacc gaacactgcatcacgctgctccgggccctggccaccaatcccgccctcaggcacatcctt gtctcccagggcctcatccgggagctttttgactataatcttcgcagaggctctgcggcc atgcgggaggaggtccgccagctcatgtgcctcctgactcgagacaatccagaagccacc cagcaaatgaatgacctgatcattggcaaagtctccacagccttgaagggccactgggcc aatcctgatctggcaagtagccttcagtatgaaatgctgttgctcacggactctatctcg aaggaggacagctgctgggaacttcgcttacgctgtgcgctcagcctcttccttatggct gtgaacatcaagactcccgtggttgttgagaacattaccctcatgtgcctgcggatcttg cagaagctgattaaaccacctgctccaactagcaagaagaacaaggatgttccggtcgag gccctcaccacagtgaagccgtactgcaacgagatccatgcccaggcacaactctggctc aagagagaccccaaagcctcctacgaagcctggaagaagtgtcttcccatcagagggatt gagggtaacgggaagtcccccagcaagtcagagctccgccatctctatctgaccgagaag tacgtgtggaggtggaagcagtttctgagtcgtcgggggaagaggacatcccccttggat ctcaaactcggccataacaactggctgcggcaagtgctcttcactccagcaacgcaggct gcacggcaggcagcctgtaccatcgtggaggctctagccaccattcccagccgcaagcag caggtcctcgacctcctcaccagttacctggatgagttgagcatcgctggcgagtgtgcc gccgagtacctggctctctaccagaagctcatcacttcagctcactggaaagtctacctg gcagctcgaggcgtcctgccctatgtgggcaacctcatcaccaaggaaatagcccgcttg ctggccctggaggaggccaccctgagcactgatctgcagcagggctatgccctcaagagt ctcacaggccttctttcctcctttgtcgaggtggaatccatcaaaaggcactttaaaagt cgcttggtgggtaccgtgctgaatggatacctgtgcttgcggaagctggtggtgcagagg accaagctgatcgatgagacccaggacatgctgctggagatgctggaggacatgaccaca ggtacagagtcggaaaccaaggccttcatggccgtgtgcattgagacagccaagcgctac aatctggatgactaccggactcctgtcttcatctttgagcggctctgcagcatcatttat cccgaggagaatgaagtcactgagttctttgtgaccctggagaaggatccccaacaagaa gacttcttacagggcaggatgcctgggaacccatatagcagcaatgagccaggcattggg ccgctcatgagggatataaagaacaagatttgccaggactgtgacttggtggctctcctg gaggatgatagtgggatggagctcctagtgaacaataaaatcatcagtttggaccttcct gtggccgaggtttacaagaaggtctggtgtaccacgaacgagggagagcccatgaggatt gtttatcgaatgcgggggctgctgggtgatgctaccgaggagtttattgagtccctggac tccaccacagatgaagaagaggatgaggaagaagtgtataagatggctggtgtgatggcc cagtgtgggggcctggaatgcatgctcaacagactggcagggatcaaagatttcaagcag ggacgccaccttctaacagtgctgctgaaattgttcagttactgcgtgaaggtgaaagtc aaccggcagcagctggtcaagctggaaatgaacactctgaacgtcatgctggggactctt aacttggccctcgttgctgagcaagaaagcaaggacagtggtggagcagctgtggccgag caggtgcttagcatcatggagatcattctggatgagtccaacgccgagcctctgagtgag gacaagggcaacctcctcctgacgggtgacaaggatcaactcgtgatgctcctggaccag atcaatagcacctttgttcgctccaaccctagcgtgctccagggcttgcttcgcatcatc ccatacctttcctttggagaggtggagaaaatgcagatcttggtggagcggttcaatctt ttatggtcgtctttgctctttcctcctaggtacgatgaggaccacagtggcgatgataaa gtcttcctggactgcttctgtaaaatagcagccggcatcaagaacaacagcaatgggcat cagctgaaggatctgattctccagaagggaatcacccagagtgcacttgactacatgaag aagcacattcccagtgccaagaatttggatgctgacatctggaaaaagtttttgtctcgt ccagccctgccatttatcttgaggcttcttcgggggctggccatccagcaccctgccacc caggttctgattggaactgactccatcacaaacctgcataaactggagcaggtgtccagc gatgagggcattgggaccctggcagagaacctgctggaggcgctgcgggaacaccctgac gtgaacaagaagattgacgcggcccgcagggagacacgggctgagaagaagcgcatggcc atggccatgaggcagaaggctttgggcacgctgggcatgacgacgaatgaaaagggccag gttgtgaccaagacggcgctcctgaagcagatggaggagctgattgaggagccgggcctc acgtgctgcatctgcagggaggggtacaagttccagcccaccaaggtcctgggcatttac accttcaccaagcgggtagcgttggaggagatggagaacaagccccggaagcagcagggc tacagcaccgtgtcccacttcaacatcgtgcactacgactgccacctggctgctgtcagg ctggctcggggccgggaagagtgggagagtgccgcccttcagaacgccaacactaagtgc aacgggctccttccggtctgggggccccacgtccctgagtcagcttttgccacctgcctg gcaaggcacaacacttacctccaggagtgcacgggccagcgggagcccacgtaccagctc aacatccacgacatcaagctgctcttcctgcgcttcgccatggagcagtcgttcagtgcg gacaccggtgggggcggccgggagagcaacatccacctgatcccgtacatcgttcacact gtgctttacgtgctgaacacaacccgagcaacttcccgagaggagaagaacttccaggcc tttctggagcagcccaaggagaagtgggtggagagtgcctttgaagtggacgggccccac tacttcacagtcctggccctccacatcctgccccctgagaagtggagagccacacgcgtg gaaatcctgcggaggctgctggtgacctctcaggcccgggcagtggctccagggggagcc accaggctgacagacaaggcagtgaaggactactctgcttatcgctcctcccttctcttt tgggccctcgtcgatctcatttataacatgtttaagaaggtgcctaccagcaacacggag ggaggctggtcctgctctctagcggaatacatccgccacaacgacatgcccatccacgaa gcagccgacaaggccctgaaggccttccaggaggagttcatgccagtggagaccttctcg gagttcctcgacgctgccggtctcttatcagaaatcactgacccagagagcttcctgaaa gacctgttgaactcagtcccctga

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