Camelus bactrianus (Bactrian camel): 105078489 Help Entry 105078489         CDS       T07534                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism cbai  Camelus bactrianus (Bactrian camel) Pathway cbai01521   EGFR tyrosine kinase inhibitor resistance cbai01522   Endocrine resistance cbai04010   MAPK signaling pathway cbai04012   ErbB signaling pathway cbai04014   Ras signaling pathway cbai04062   Chemokine signaling pathway cbai04068   FoxO signaling pathway cbai04072   Phospholipase D signaling pathway cbai04150   mTOR signaling pathway cbai04151   PI3K-Akt signaling pathway cbai04510   Focal adhesion cbai04540   Gap junction cbai04630   JAK-STAT signaling pathway cbai04650   Natural killer cell mediated cytotoxicity cbai04660   T cell receptor signaling pathway cbai04662   B cell receptor signaling pathway cbai04664   Fc epsilon RI signaling pathway cbai04714   Thermogenesis cbai04722   Neurotrophin signaling pathway cbai04810   Regulation of actin cytoskeleton cbai04910   Insulin signaling pathway cbai04912   GnRH signaling pathway cbai04915   Estrogen signaling pathway cbai04917   Prolactin signaling pathway cbai04926   Relaxin signaling pathway cbai04935   Growth hormone synthesis, secretion and action cbai05034   Alcoholism cbai05160   Hepatitis C cbai05161   Hepatitis B cbai05163   Human cytomegalovirus infection cbai05165   Human papillomavirus infection cbai05200   Pathways in cancer cbai05205   Proteoglycans in cancer cbai05206   MicroRNAs in cancer cbai05207   Chemical carcinogenesis - receptor activation cbai05208   Chemical carcinogenesis - reactive oxygen species cbai05210   Colorectal cancer cbai05211   Renal cell carcinoma cbai05213   Endometrial cancer cbai05214   Glioma cbai05215   Prostate cancer cbai05220   Chronic myeloid leukemia cbai05221   Acute myeloid leukemia cbai05223   Non-small cell lung cancer cbai05224   Breast cancer cbai05225   Hepatocellular carcinoma cbai05226   Gastric cancer cbai05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:cbai00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105078489 (SOS2)    04012 ErbB signaling pathway     105078489 (SOS2)    04014 Ras signaling pathway     105078489 (SOS2)    04630 JAK-STAT signaling pathway     105078489 (SOS2)    04068 FoxO signaling pathway     105078489 (SOS2)    04072 Phospholipase D signaling pathway     105078489 (SOS2)    04151 PI3K-Akt signaling pathway     105078489 (SOS2)    04150 mTOR signaling pathway     105078489 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105078489 (SOS2)    04540 Gap junction     105078489 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105078489 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105078489 (SOS2)    04660 T cell receptor signaling pathway     105078489 (SOS2)    04662 B cell receptor signaling pathway     105078489 (SOS2)    04664 Fc epsilon RI signaling pathway     105078489 (SOS2)    04062 Chemokine signaling pathway     105078489 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     105078489 (SOS2)    04912 GnRH signaling pathway     105078489 (SOS2)    04915 Estrogen signaling pathway     105078489 (SOS2)    04917 Prolactin signaling pathway     105078489 (SOS2)    04926 Relaxin signaling pathway     105078489 (SOS2)    04935 Growth hormone synthesis, secretion and action     105078489 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     105078489 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     105078489 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105078489 (SOS2)    05206 MicroRNAs in cancer     105078489 (SOS2)    05205 Proteoglycans in cancer     105078489 (SOS2)    05207 Chemical carcinogenesis - receptor activation     105078489 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     105078489 (SOS2)    05231 Choline metabolism in cancer     105078489 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     105078489 (SOS2)    05225 Hepatocellular carcinoma     105078489 (SOS2)    05226 Gastric cancer     105078489 (SOS2)    05214 Glioma     105078489 (SOS2)    05221 Acute myeloid leukemia     105078489 (SOS2)    05220 Chronic myeloid leukemia     105078489 (SOS2)    05211 Renal cell carcinoma     105078489 (SOS2)    05215 Prostate cancer     105078489 (SOS2)    05213 Endometrial cancer     105078489 (SOS2)    05224 Breast cancer     105078489 (SOS2)    05223 Non-small cell lung cancer     105078489 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     105078489 (SOS2)    05160 Hepatitis C     105078489 (SOS2)    05163 Human cytomegalovirus infection     105078489 (SOS2)    05165 Human papillomavirus infection     105078489 (SOS2)   09165 Substance dependence    05034 Alcoholism     105078489 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105078489 (SOS2)    01522 Endocrine resistance     105078489 (SOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH PH_19 IQ_SEC7_PH PH_10 Motif Other DBs NCBI-GeneID:  105078489 NCBI-ProteinID:  XP_010965355 UniProt:  A0A9W3H0V0 LinkDB All DBs Position Unknown AA seq 1377 aa AA seqDB search MEQAPSGFPGDAYSRLEAPAPGRRLSPLRGAHAPCGAAPASLENERRAEGPYEFFSEENS PKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLCMAQPRTVQDVEERVQK TFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEY ISADILKLAGNYVFNIRHYEISQQDIEVSMCADKVLMDMFDQDDIGLVSLCEDEPSSSGE LNYYDLVRTEIAEERQYLRELNMIIKVFREAFISDRKLFKPSDIEKIFSNILDIHELTVK LLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPKFNEHFSKLMARP AVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEHEDRECLNQAIT ALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIG QCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPGYSSAEYRLKEKFVMRK IQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVL LKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNVQSRSGIPIIKGGTVVKLIERLTYHMY ADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLAVEKGEQPISADLKRFR KEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIK RKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPIEIARQLTLLESDLYRK VQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEI LQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVK LKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQP YCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSP GIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSA SSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFD HDASNSKGNTKSDDDPPPAIPPRQPPPQKVKPRVPAPTGALDGPLHSPPPPPPRDPLPDT PPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPNTPPSTPSPRVPRRCY VLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLLENAETPQ NT seq 4134 nt NT seq  +upstreamnt  +downstreamnt atggaacaggctcccagcgggttcccaggagacgcgtactcccgcctcgaggcccccgcg cccggccggcgcctcagcccgctccgcggcgcgcatgctccatgcggggctgctccagct agcctggaaaatgagcgccgtgcggaggggccttacgagttcttcagcgaagagaacagt ccgaaatggcggggactgttggtctcggccctgcgaaaggttcaggagcaagtacatccc aatctctcagctaatgaagagtctctctattatattgaagagctgatttttcagctgctt aataaattatgcatggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaaa accttccctcatccaattgataaatgggctattgctgatgcacagtctgccatagagaaa cgaaaacgaaggaatcctctcttactgcctgtggacaaaatccatccttcattgaaggaa gttttagggtacaaagtggactaccacgtgtccctatatattgtggctgtactagagtat atctcagctgatattttaaaattggctggtaattatgtttttaatatccgacattatgaa atatcccaacaggacattgaagtgtcaatgtgtgcagataaggttttgatggacatgttt gatcaggatgacataggcttggtttctctctgtgaagatgaacctagttcttcaggtgaa ttaaattactatgaccttgtcagaactgaaattgcagaagaaagacagtatctacgggaa ctaaatatgatcataaaagtgtttcgagaagcttttatttctgaccgaaagctgtttaaa ccttctgatattgaaaagattttcagtaacattttagatatacatgaactgaccgtgaaa cttttaggtttgattgaagatacagttgaaatgactgatgaaagcagccctcatccctta gctggcagttgttttgaagatttggcagaagagcaagcatttgatccttatgaaacatta tctcaggatattctttcaccaaaatttaatgaacatttcagtaagttgatggccagacct gcagtggctctacactttcagtccattgctgatggttttaaagaggcagttcgttatgtc cttccacgccttatgctggtgccagtgtatcattgttggcactattttgaattattaaag caattgaaagcatgtagtgaagagcacgaagacagagaatgtttgaaccaagctattact gctctaatgaatctccaaggtagtatggaccgaatttacaagcagtattcacctagacgc cgacctggggatcccgtttgccctttttataatcgtcaattaagaagcaagcacctggct attaaaaaaatgaatgaaattcagaaaaacatagatggatgggaaggcaaagatattgga cagtgttgtaacgaatttattatggaaggcccattgacaagaattggtgctaaacatgaa cggcatatttttctctttgatggcttgatgattagctgcaaacccaatcatagccagtca cgacttccaggatacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaa atacaaatatgtgataaagaagatacttgtgagtgcaaacacgcctttgaattagtatcc aaggatgaaaacagcataatatttgctgctaagtctgctgaagagaaaaataattggatg gcagcacttatttctctccattatcgtagtacccttgatcgaatgctagattcagtatta ttgaaggaagaaaatgaacaaccactgagattaccaagtccagaagtgtatcgttttgtg gtaaaagactctgaggaaaacattgtttttgaagacaacgtgcaaagtagaagtggaatc cccattattaaaggaggaactgtggtgaaattaattgaaaggttaacataccatatgtat gcagatcccaattttgttcgtacttttcttactacatatcgttcattttgtaaaccacag gaattgctaagcttactaattgaacgatttgaaattccagagccagaacctacagaagca gataaattggcagtagagaaaggcgagcagccaatcagtgcagaccttaaaaggtttcgc aaggaatacgtccaaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaa caccatttttatgactttgaaagagatttggagttgcttgaaagactagagtccttcatt tcaagtgtaagagggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaag aggaagaaacaagctcaggcaaacggaataagccataatattacatttgaaagtccacct ccaccaattgaatggcatatcagtagaccaggacagtttgaaacatttgatctcatgaca cttcatccaatagaaattgcacgtcaactgacacttttggaatctgatctctacaggaaa gtccagccttctgaacttgtggggagtgtatggaccaaagaagataaagaaataaattct ccaaatttattaaaaatgattcgccacaccacaaatctcaccctctggtttgaaaaatgt attgtggaagcagaaaattttgaggaacgagtggcagtcctaagtagaattatagaaatt cttcaagtttttcaagatttgaataatttcaatggtgtattggaaatcgtcagtgcggta aattcagtgtcagtctacagactagatcatacctttgaggcattgcaagaaagaaaaagg aaaattttggatgaagctgtggaattaagtcaagatcactttaaaaaatatctagtgaaa cttaagtcaataaatccaccttgtgtgcctttttttggaatatatttaacaaatattctg aagaccgaagaagggaataatgattttttaaaaaagaaagggaaagatttaatcaatttc agtaagaggaggaaagtagctgaaattactggagaaattcagcaatatcagaatcaacct tactgtttacggatagaaccagaaatgaggaggttctttgaaaaccttaatccaatggga agtgcttctgaaaaagagtttacagattatttgttcaacaagtccctagaaattgaaccc cgaaactgcaaacagccacctcgatttcctagaaaatcgactttctctttaaaatctcct ggaataaggcctaatacaggccgacatggctctacctcaggtactttacgaggtcatcca acaccattagaaagagaaccatgcaaaataagctttagtcggattgctgaaacagagctg gaatcaacagtgtcagcaccaacctcccccaatacaccgtctactccaccagtatctgct tcttcagaccttagtgtgtttttagatgtggatctcaacagctcctgtggaagcaatagc atctttgctccagttctcttgccacattcaaagtctttcttcagttcgtgtggtagttta cataaactaagtgaagagccactgattcctcctccacttccgcctcgaaaaaagtttgat cacgatgcttcaaattccaagggaaatacgaaatctgatgatgaccccccgcctgctatt ccaccaagacaacctcctcctcaaaaggtaaaacccagagttcctgctcctactggtgca ttggacgggcctctgcatagtccacctccaccgccgccgagagatcctcttcctgatacc cctccaccggttccccttcggcctccagaacactttataaactgtccatttactcttcag ccacctccactgggacatcttcacagagatccagactggttcagagatgttagtacgtgt ccaaactctccaaacactcctcctagcacaccctctccaagggtaccacgtcgatgctac gtgctcagttctagtcaaaataatcttgctcatcctcaggctccccctgttccaccaagg cagaattcaagccctcacctaccaaaactgccaccaaagacttacaaacgggagctctcg caccccccgttgtatagactgcctttgctagaaaatgcagaaactcctcaatga

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