Camelus bactrianus (Bactrian camel): 105081372
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Entry
105081372 CDS
T07534
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
cbai
Camelus bactrianus (Bactrian camel)
Pathway
cbai05012
Parkinson disease
cbai05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
cbai00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105081372 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
105081372 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cbai01001
]
105081372 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cbai04131
]
105081372 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cbai04147
]
105081372 (LRRK2)
Enzymes [BR:
cbai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105081372 (LRRK2)
Protein kinases [BR:
cbai01001
]
Serine/threonine kinases: TKL group
LRRK family
105081372 (LRRK2)
Membrane trafficking [BR:
cbai04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
105081372 (LRRK2)
Exosome [BR:
cbai04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
105081372 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_9
LRR_14
WD40_CDC20-Fz
Arf
WDR55
G-alpha
Beta-prop_RSE1_2nd
Beta-prop_EML_2
Beta-prop_BBS7
LRR_NXF1-5
LRR_13
Ank_2
WD40_Prp19
Beta-prop_EML
Kdo
LRR_6
Beta-prop_WDR19_1st
GTP_EFTU
MMR_HSR1
Beta-prop_RIG_2nd
MobB
PduV-EutP
T2SSE
nSTAND3
TniB
Motif
Other DBs
NCBI-GeneID:
105081372
NCBI-ProteinID:
XP_010968834
UniProt:
A0A9W3FAX9
LinkDB
All DBs
Position
Unknown
AA seq
2529 aa
AA seq
DB search
MARGSCQGCEEEEDEETLKKLIVRLNNVQEGKQIETLVQILEDMLVLTYADYASKLFQDK
NVHVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGNDWEVLGVHQLI
LKMLTVHNASVTLSTVGLKTLDLLLTSGKITLLILEEEHDIFLLIFDAMRTFSANDEIQK
LGCKALHVLFEKVSEEQLTEFVENKDYMILLSALNSFKDEEEIVLHVLHCLHSLAIPCNN
VEVLMSGNVRCYNIVVEAMKAFPINEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKA
VQRYSKNADLQIAALSCLALLTETIFLNQDLEEKNEHQENEEEEEEEKLFWLEACYKALT
RHRKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQAS
ANALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEAAESGCKMLNHLFEGSNTSLD
TMAAVAPKIITVMKSHQTSLSVQLEALRAILHFIVPGFPEESTEDCEYQHKLNMVKKQCF
RNDIHKLVLAAVNRFIGNPGIQKCGLKVISSIACFPDALEVLTLEGAVDSVLHTLQMYPD
DQEIQCLGLSLIGCLITKKNLCTGTGHLLAKILISSLQRFKDIGEVQIKGFQAIFTILEL
SVSFSKLLLQHSFDSVIFHQMSSGVLEQKDQQFLSLCCKCFAKLALDDELKSVMLQRACD
QNNSIMVECLLLLGADANRAKEATSLICQVCEKASSPKLVELLLDSGSREQDVRRALTVS
IGKGDSRIISLLLRRLALDLANNSICLGGFCMGKIEPSWLGPLFPDKTSQLRKETNMGST
LARMVLRYQMKSAVEEGAASGSNGNLSEEILDKFDEWTFIPESYVDSVFGQSDDLDSEGS
EGSFLVKKKSNSISVGEFYRDPALQRCSPNLQRHSSSLGPIFDHEDLLKRKRKILSSDDS
LRMSKLQSHVRHSDSVSSLASERDCITSLDLSANELRDIDALSQKSCISGHLEHLEKLEL
HQNALTSFPQQLCETLKCLTHLDLHSNKFTSFPPYLLKMNCIANLDVSRNDIGPSVVLDP
AVKCPTLKQLNLSYNQLSSLPENLGDVVEKLEQLILEGNKISEICSPLSLKELKILNLSK
NHISSLSEDFLETCPKVESLSARMNFLVAMPFLPSSMTSLKLSQNRFTCVPEAILSLPHL
RSLDMSSNDIQYLPGPVHWRSLNLRELLFSHNRISVLDLSEKACAWSRVEKLHLSHNKLK
EIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKDI
IRFLQQRLKKAVPYNRMKLMIVGNTESGKTTLLQQLMKIKKSDLGMQGATVGIDVKDWPI
QVRGKGKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNI
KARASSSPVILVGTHLDVSDEKQRKACIGKITKELLNKRGFPAIRDYHFVNATEESDALA
KLRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPTEFPVIDRKRLLQLVE
DHQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPRWLCKVMAQILTVKVEGC
PKHPKGIISRRDVEKFLSKKKRFPKNYMSQYFKLLEKFQIALPNGEENLLVPSSLSDQRP
VIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGREQALRPNRMYWRQGI
YLIWSPEAYCLVGSEVLDNHGESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEI
DICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLINPDQPRLTIPISQIAPD
LILADLPRSIMLNNDELEFEQAPEFLLGDGSFGSVYQATYEGEEVAVKIFNKHTSLRLLR
QELVVLCHLHHPSLVSLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHV
ADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGF
RAPEVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKE
YGCAPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRRISIPKNFTVECMVAS
NHISKNASIWLGCGHTDKGLLSLLDLNTERYISEEVTDSRILCLALVHLPVEKESWIVSG
TQSGTLLAINTEDERKRHTLEKMTDSVTCLYCHSFSRQSKQKNFLLVGTADGNLAIFEDK
TVKCKGAAPLKILNIGNVSTPLMCLSESMNSTEKNIMWGGCGTKIFSFSDDFTIQKLIES
RTNQLFSYASYSDSNIIAVVVDTVLYVAKKNSPFVEVWDKKTEKLCELIDCVHFLKEELV
KVNKESKHKMSYSGRVKTLSLQKNTALWIGTGGGHILLLDLSTRRIIRIIHNFCDSVRVM
MTAQLGNLKNVMLVLGYNRKNTEGMQHQKEIQSCLSVWDINLPHEVQNLEKHIEVRKELA
EKMRRISVE
NT seq
7590 nt
NT seq
+upstream
nt +downstream
nt
atggccaggggcagctgccagggctgcgaggaggaggaggacgaggaaactctgaagaag
ttgatagtcaggctgaacaatgtccaggaaggaaaacagatagagacgctggtccaaatc
ctggaggatatgctggtgctcacttatgccgactacgcctccaagttatttcaagacaaa
aatgtccacgtgcctctgttgatcgtcttggactcgtatatgagagtcgctagcgtgcag
caggtgggttggtcacttttatgcaaattaatagaaatctgtccaaatacaatgcaaagc
ttaatgggaccccaggatattggaaacgattgggaagttcttggggttcaccaactgatt
cttaaaatgctaacagttcataatgccagtgtcaccctgtcaacggttggattgaagacc
ttagatctccttctaacatcaggtaaaatcactttgctgatattggaggaagaacatgat
attttcttgttaatttttgatgccatgcgcacattttcagccaatgatgaaatccagaaa
cttggatgcaaagctttacatgtgctgtttgaaaaagtttcagaggagcaactgactgaa
tttgttgaaaataaagattatatgatactgctaagtgcgttaaacagttttaaggatgaa
gaggaaattgtgctgcatgtattgcactgtttacattccctagcgattccttgcaataat
gttgaagtcctcatgagtggcaatgtcagatgttataatattgtggtagaagccatgaaa
gcattccctatcaatgaaaaaattcaagaagtgagttgctgcttgctgcataggcttaca
ttaggtaatttttttaatatcttggtgttaaacgaggtgcatgagttcgtggtaaaagcc
gtgcagcgatattcaaagaacgcagacttacagatcgcggcactcagctgtttggcgctc
ctcactgagaccattttcttaaatcaagacttagaggaaaagaatgagcatcaggagaat
gaggaggaggaggaagaagaaaagttgttttggctggaagcctgttacaaagcattgaca
cggcacagaaagaacaagcatgtgcaggaggccgcatgctgggccctgaacaatctcctc
atgtatcaaaacagtttacacgagaagattggagatgaagatggccagttcccggctcac
agggaagtgatgctgtccatgctaatgcattcttcttcaaaagaagtcttccaggcatct
gcaaatgcgttgtcaactctgttagaacaaaatgttaatttcagaaaaatcctgttgtca
aaaggaatatatctgaatgtgttggaattaatgcagaagcatatacattctcctgaggcg
gctgaaagcggctgtaaaatgctaaatcatctttttgaaggaagtaacacctccctggat
acaatggcagcagtggcccccaaaataataacagttatgaaaagtcatcagacatcgtta
tcagtgcagctggaggcacttcgagctattttacattttatagttccaggcttcccagaa
gaatccacggaagactgtgaatatcaacataagctaaatatggttaaaaaacaatgtttc
aggaatgatattcacaaactggtcctagcagccgtgaacaggttcattggaaatcctggg
attcagaaatgtggattaaaagtaatttcttctatagcatgttttcctgatgcattagag
gtgttaaccctggaaggtgctgttgattcggtgctccacacgctgcagatgtatccggat
gaccaagaaattcagtgtctgggtttgagtcttataggatgcttgattacaaagaagaat
ttatgcacagggactgggcatcttttggcaaaaattctgatttccagcttacaacgattt
aaggatattggtgaagtacagattaaaggatttcaggcgatctttacgatactggagttg
tcagtgtctttttccaagctactgctgcagcattcctttgattcagtaatattccatcag
atgtcttccggtgtcctggaacaaaaggatcagcagtttctaagcctctgttgcaagtgc
tttgcaaaactagctctggatgatgaattaaagagcgtgatgctccagagggcgtgtgat
cagaataacagcatcatggttgaatgcttgcttctgttgggagcagacgccaatcgagca
aaagaggcaacctctttaatttgtcaggtgtgtgagaaagcgagcagtcccaaactggtg
gaactgttactggacagtgggtcccgggaacaagatgtgcggagagctctgacagtcagc
attgggaaaggtgacagccggatcatcagcctacttttaaggaggcttgccctggatctg
gccaataatagcatttgccttggaggattttgtatgggcaaaattgaaccttcttggctg
ggtcctttatttccagataagacatctcagttaaggaaagaaacaaatatgggctccacc
ctagcaagaatggtgctcagatatcagatgaaaagtgctgtggaagaaggagcagcctca
ggcagcaatggcaatctttctgaagaaatactggataaatttgacgaatggaccttcatt
cctgagtcttacgtggacagtgtgtttggtcaaagtgatgacctggatagtgaaggaagt
gaaggctcatttcttgtgaaaaagaaatcaaattcaattagcgtaggagaattttaccga
gatcctgccttgcagcgttgctcaccaaatttgcaaagacattccagttcgttgggaccc
atttttgatcatgaagatttactgaagagaaaaagaaaaatactgtcctcagatgattca
ctcagaatgtcaaaactccagtcacatgtgaggcattcagacagcgtttcttccctggct
tctgagagagactgtattacatcattagacctttcagccaatgaactcagagatattgac
gccctgagccagaagtcctgcataagcggtcatctggagcaccttgaaaagctggagctt
caccagaatgcactcacgagctttccacaacaactctgtgaaactctgaagtgtttgaca
catttggacttgcacagtaataaatttacatcatttcctccctacttgttgaaaatgaat
tgtattgccaacctcgatgtctctcgaaacgacattggaccctcagtagttttggatcct
gctgtgaagtgcccgaccttgaaacagcttaacctctcctataatcagctgtcttctctt
cctgagaaccttggtgatgtggtagagaaactggagcagctcattttagaaggcaataaa
atatcagaaatatgttcccctttgagcctgaaggaactgaagattttaaaccttagtaaa
aaccacatttcatctctgtcggaggactttctggagacttgtcctaaagtggagagttta
agtgccaggatgaattttcttgttgctatgccttttttgccttcctccatgacaagccta
aaattatctcagaacagattcacatgtgttccggaagcaattttaagtcttccacacctg
cggtccttagatatgagcagcaatgatattcagtatctgccgggtcctgtgcactggaga
tctctgaacttacgggaactcttgtttagccataatcggatcagtgtcttggacttgagt
gaaaaagcctgtgcctggtctagagtagagaaactacatctttcccataataaactgaaa
gagattcctcccgagattggctgtctggaaaacctgacatctcttgatgttagttacaac
ttggaactgagatcttttcccaatgaaatggggaaattaagcaaaatatgggatcttcct
ttggatgaactgcatcttaattttgattttaaacatataggatgtaaagccaaagacatc
ataaggttccttcagcagcggttaaaaaaggctgtgccttataaccgaatgaagcttatg
attgtgggaaatactgagagcggtaaaaccaccttattgcagcaattaatgaaaatcaag
aaatcagatcttgggatgcaaggtgccacagttggcatagacgtgaaagactggcccatc
caagtaagaggcaaagggaagaaagaccttattctaaacgtgtgggattttgcaggtcgt
gaggagttctacagcactcatccccacttcatgacccagcgagccctgtatcttgctgtc
tatgacctcagcaaagggcaagctgaagtggacgccatgaagccttggctcttcaatata
aaggcgcgtgcttcttcttcgcccgtgattcttgttggcacacatttggatgtttctgat
gagaagcagcgcaaagcctgtataggtaaaatcaccaaggagctcttgaacaagcgaggg
tttcctgccatacgggattaccactttgtaaatgccacggaggaatccgacgctttggca
aaacttcggaaaaccatcattaatgagagcctgaatttcaagatccgagatcagcctgtt
gttgggcagctgattccagactgctatgtagaacttgagaaaatcattttatcggagcgt
aaaaatgtgccaactgaatttcctgtaattgaccggaaacgattattacagctcgtggaa
gaccatcagctgcagttggatgaaaatgagctccctcatgcagttcacttcctaaatgaa
tcaggggttcttcttcattttcaagacccagcactgcagttaagtgatttatattttgtg
gaacccaggtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctgt
cccaaacatcctaagggaattatttcacgtagagatgtggagaagtttctttcaaagaaa
aagagatttccaaagaactacatgtcacaatactttaaactcctagagaaattccagatt
gccttgccaaacggtgaagaaaatttgctggtcccaagcagtctgtctgaccaaaggcct
gtgatagagctcccgcactgtgagaactctgaaattatcattcggctctacgaaatgcct
tattttccaatgggcttttggtcgagattaatcaatcgattacttgaaatttcaccttac
atgctttcaggaagagagcaagcacttcgcccaaacagaatgtactggcgacaaggcatc
tacctgatctggtctcctgaagcttactgcctggtaggatctgaagtcttagacaatcac
ggggagagtttcttaaaaattacagttccttcttgtagaaaaggctgtattcttttgggc
caagttgtggaccacattgattctctcatggaagagtggtttcctgggttattggagatt
gatatttgtggcgaaggagaaactctgttgaagaaatgggccttgtatagttttaacgat
ggggaagagcatcaaaaaatcttacttgacgacttgatgaagaaagcagaagaaggagac
cttctaataaatccagatcaaccaaggctcaccattccaatatctcagattgcccctgac
ttgattttggctgacctgcctagaagcattatgttgaacaatgatgaactggaatttgaa
caagctccagagtttctcttaggcgatggcagttttggatccgtttatcaagcaacctat
gaaggagaagaagtggctgtgaagatctttaataaacatacatcactcagactgctaaga
caagagctggtggtgctctgccacctccaccatcccagcttagtatctctgctggcggct
gggattcgtcctcgaatgttggtgatggagttggcctccaaggggtccctggatcgcctg
cttcagcaagacaaagccagccttaccaggacgctgcagcacaggatcgcgctccacgtg
gctgatggcttgagatacctccactcagccatgattatataccgtgacttgaagccccac
aacgtgttgctcttcaccctgtatcccaacgctgccatcattgccaagattgctgactac
gggattgcccagtactgctgtagaatggggataaaaacgtccgagggcacaccagggttc
cgtgcacctgaagttgctagaggaaatgttatttataaccagcaagctgatgtatattca
tttggtttgcttctctatgacattttgacaactggaggcagaatagcagagggtttgaag
tttccaaatgagtttgatgaattggcaatacaaggaaaattacctgatccagttaaagaa
tatggttgtgccccatggcccatggttgagaagttaattaaaaagtgtttgaaagaaaat
cctcaagaaagacctacttctgcccaggtctttgacattttgaattcagctgagttaatc
tgtctcatgagacgtatatcaatacctaaaaacttcactgttgaatgcatggttgcttca
aatcatattagcaagaatgcaagcatttggctgggctgtgggcacactgacaaaggactg
ctctcacttcttgacttaaatactgaaagatacatttctgaggaagttactgacagcaga
atactatgcctggccttggtgcatcttccagtggaaaaggaaagctggatcgtgtctgga
acccagtctggcacgctcctcgccatcaatactgaagacgagagaaagaggcataccctt
gaaaagatgactgattctgttacttgcttgtactgccattccttctccaggcaaagcaag
caaaaaaatttcctcttagtgggaactgctgatggcaacttagcgatttttgaagataaa
actgttaagtgtaaaggagctgcccctttgaagatactcaatataggaaatgtcagcacc
cccctgatgtgtctgagtgaatctatgaattctactgaaaaaaacatcatgtggggagga
tgtggtacaaaaattttttcattttctgatgatttcaccattcagaaactcattgagagc
aggacaaatcagctgttttcttatgcatcttacagtgattccaacatcatagcagtggtg
gtagacacggttctttatgttgctaagaaaaatagcccatttgtggaagtgtgggacaag
aagactgaaaaactctgtgaactgatagactgtgtgcactttttaaaggaggaactggta
aaagtgaacaaggaatcaaaacacaaaatgtcttattctgggagagtgaaaactctcagc
ctgcaaaagaacactgctctctggataggaactggagggggccacatcttactccttgat
ctctcaacgcgtcgaattatacgtataattcacaacttttgtgattctgttagagttatg
atgacagcacagctaggaaaccttaaaaatgtcatgctggttctgggatataatcggaaa
aatactgaaggtatgcaacaccaaaaagaaatacagtcttgcttgtctgtttgggacatc
aatctgccacatgaagtgcaaaatttagagaaacatattgaagtgaggaaagaattagct
gaaaaaatgagaagaatatctgttgaataa
DBGET
integrated database retrieval system
