Clostridium botulinum H04402 065: H04402_01528
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Entry
H04402_01528 CDS
T02076
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cbj
Clostridium botulinum H04402 065
Pathway
cbj00300
Lysine biosynthesis
cbj00550
Peptidoglycan biosynthesis
cbj01100
Metabolic pathways
cbj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cbj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
H04402_01528
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
H04402_01528
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
H04402_01528
Enzymes [BR:
cbj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
H04402_01528
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF7790
Motif
Other DBs
NCBI-ProteinID:
CBZ03340
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Position
1654467..1655855
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AA seq
462 aa
AA seq
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MENIKLEEIIKAVNGELVITGEKDEYNSVSTDTRKIEKGDIFIALKGENFNGNNFVEMAI
EKGAALCIVSEINFSEGKVGKSSYVIKVENTNKALLDLAKYYRSKLDIKVVAITGSTGKT
STKDLVAAVLSEKYKVFKTEGNFNNEIGLPLMIFKLDKSYDIAVLEMGMNHFNEIHNMSE
AAKPDIAIITNIGISHIENLGSRENILKAKLEITDFFCKDSILIINGDDDLLSNFESDKF
KVYKIGTDKKFDFNGDNLNLEAENIEFDILEQGKTAYKCFGVNVPGKHNVLNSLTAIACG
RVLDINYRDIQTGIKNLKATSMRLDIVKEKGFTIINDCYNASPDSMKAAIDVMKNIKGKR
TIALLGSMMELGNEGYRAHREVSEYAKEKGIDLLFSIGEFSEAYKEGFEEINKENYKSFL
NNQEAAKYIKNIIKDGDIILIKASRAMKLEEIVKELRIKQEK
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atggaaaatattaaactagaagaaataataaaagcagttaatggtgagttagtgataact
ggagaaaaagatgaatataattcagtaagcacagatacaagaaaaatagaaaagggagat
atatttatagccttaaaaggagaaaattttaatggaaataactttgtagaaatggccata
gaaaagggtgccgctttatgcatagtaagtgaaataaattttagtgagggaaaagtgggc
aaatcttcctatgtaataaaggtagagaatactaataaggctcttttagatttagctaaa
tactatagaagtaaactagatataaaagtggttgctattactggatctacaggaaaaaca
tctacaaaggatttagtggcagctgtgctttcagaaaaatataaggtatttaaaacagag
ggaaattttaataatgagataggacttcctcttatgatttttaaattagataaaagttat
gatatagcagttttagaaatgggaatgaatcattttaatgaaatacacaatatgtcagaa
gcagcaaaaccagatatagctataataactaatataggtatatctcatatagaaaattta
ggatctagggaaaatattttaaaagcaaaactagaaataacagatttcttctgtaaggat
agtattttaataataaatggagacgatgatcttctatcaaattttgaaagtgataaattt
aaggtatacaaaataggcacagataaaaaattcgattttaatggagataatttaaattta
gaggcagagaatatagaatttgatatattagaacaaggtaaaacagcttataaatgtttt
ggcgtaaatgtacctggaaagcataatgtgcttaattctcttacagctatagcttgtgga
agagttttagatataaattacagggatatacaaactgggataaaaaatttaaaagctact
tctatgagattagatatcgttaaggaaaagggatttactataataaatgattgttataat
gcaagtccggattctatgaaagcagctatagatgtaatgaaaaatataaagggaaaaagg
actatagctttattaggttctatgatggaactcggaaatgaggggtatagagcccataga
gaagtttctgaatatgcaaaagaaaagggaatagatttattattttctataggagagttt
agtgaagcctataaggagggttttgaagaaataaacaaagagaattataaaagcttttta
aataatcaagaagcagcaaaatacataaaaaatataataaaagatggtgatataatatta
attaaagcatctagagctatgaagctagaagaaatagtaaaagaactaaggataaaacaa
gaaaaatag
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