Clostridium botulinum A ATCC 3502: CBO0921
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Entry
CBO0921 CDS
T00533
Symbol
hemD
Name
(GenBank) porphyrin biosynthesis protein [includes: uroporphyrin-III C-methyltransferase and uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cbo
Clostridium botulinum A ATCC 3502
Pathway
cbo00860
Porphyrin metabolism
cbo01100
Metabolic pathways
cbo01110
Biosynthesis of secondary metabolites
cbo01120
Microbial metabolism in diverse environments
cbo01240
Biosynthesis of cofactors
Module
cbo_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
cbo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CBO0921 (hemD)
Enzymes [BR:
cbo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CBO0921 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CBO0921 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
CAL82474
UniProt:
A5I0B3
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All DBs
Position
1027633..1029093
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AA seq
486 aa
AA seq
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MSKVYLIGAGPGDEELITLKAIRALKKCTAVMYDRLANGELLKYLAPNCEIYYCGKEPGC
HYKSQDEINKMLVKLAKEGHIVGRIKGGDPYVFGRGGEEALDILEENIEFEVIPGVTSPV
SVLNYAGIPITHRGISRGFHIFTAMTKDKLDIDWKSVVNIGGTLVFLMGLGRLELITKGL
IENGMDKEGKVAVVMKGTTSKQKKVIGNLENIVEKVKEAKLESPVIIVVGEVVSFSDKLN
WYEKKPLFGRNICITRTKEQAKELKVQLLDLGAEVTEINSIEIKNTEDNLKSYLSKLKEY
DYIALTSVNAVKIFFDYLIKENIDIRNINAKFAAIGPATSEAIRIRGIMPSIKSKHFVAE
SLFEEMRKHIQKGDKILVPRSKDARPFLVDALRKEGCTVDEVHIYGTLCGQCTYTERFED
ADTVLFTSPSTVRNMISMVGIDSIKEKSIIAIGPITAAELDKNNIECSICDEYSINGIID
KLLDLN
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atgagtaaagtatatttaattggtgcagggccaggtgatgaagaattaataactttaaaa
gccataagagccctaaaaaaatgtactgcagttatgtatgatagattagcaaatggagaa
ttgttaaaatatttagcaccaaattgtgaaatttattattgtggaaaagaaccgggctgt
cattataaaagccaggatgaaataaataaaatgctagttaaattagcaaaagaaggtcat
attgtaggaagaataaaaggtggagatccctatgtatttggaagagggggagaagaagcc
ttggatattttagaagaaaatatagaatttgaagttataccaggtgtaacttctccagta
tctgtactgaattatgcaggaattcctataacccatagaggaatatcaagagggtttcat
atttttacagctatgactaaggataaattagatatagattggaagtctgtagttaatata
ggaggaaccttagtatttttaatggggcttggaagattagaattaataactaaaggtctt
atagaaaatggaatggacaaagaaggtaaagtagcagtggttatgaaaggaactacctca
aagcaaaaaaaagttataggtaacttagaaaatatagtagaaaaagtaaaagaagctaaa
ctagagtcaccagtaataatagtagtaggagaagtagttagtttttcagataaattaaat
tggtatgaaaaaaagcctttattcggaagaaatatatgcataacccgtacaaaagagcaa
gctaaggaattaaaagttcaacttttagatttaggggctgaagttacagaaataaattct
atagaaataaaaaatacagaagataatttaaagtcttatttaagtaaattaaaggaatat
gattatatagctttaaccagtgtaaatgcagttaaaatattttttgattatttaattaaa
gaaaatatagatattagaaatattaatgctaaatttgcagctataggaccagctactagt
gaggcaataaggataagaggaataatgccaagcattaagtcaaagcattttgtagcagag
agtctttttgaagaaatgagaaagcatatacaaaagggagataaaatacttgtgcctcgt
tctaaagatgcaagaccatttcttgtggatgcattaagaaaagaaggttgtactgtggat
gaagtacatatatatggaaccctatgtggacaatgtacatatactgaaagatttgaagat
gcagatacagtattatttacaagtccatctactgttagaaatatgatttctatggtgggc
atagatagtataaaagaaaaaagtattatagcaataggtcctattacagcagcagaatta
gataaaaataatatagaatgtagtatttgtgatgaatattctataaatggcataatagat
aaacttttagaccttaactag
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