Candidatus Viadribacter manganicus: ATE48_03940
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Entry
ATE48_03940 CDS
T04422
Name
(GenBank) 2-oxoisovalerate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
cbot
Candidatus Viadribacter manganicus
Pathway
cbot00280
Valine, leucine and isoleucine degradation
cbot00640
Propanoate metabolism
cbot00785
Lipoic acid metabolism
cbot01100
Metabolic pathways
cbot01110
Biosynthesis of secondary metabolites
cbot01210
2-Oxocarboxylic acid metabolism
Module
cbot_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cbot00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ATE48_03940
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ATE48_03940
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ATE48_03940
Enzymes [BR:
cbot01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
ATE48_03940
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ANP45127
UniProt:
A0A1B1AEZ9
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Position
complement(741768..743018)
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AA seq
416 aa
AA seq
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MDDMSSRKSNALDLHIPAPRARPGDKPDFSGWSFPEPGATPKPDIDESAVEMRDFAYGLI
RVLDMEGNALGPWTPHISADDLRRGLKNMLLLRAYDERMHRAQRQGKTSFYMQSLGEEAI
SIAQAMALAPDDMCFPSYRQQGILIARGYPLVDMMHQIYSNARDPMKGRQLPVMYSSKKD
GFFTISGNLATQVPQAVGWAMASAYSNDGRIAAAWLGEGSTAEGDFHAAMTFANVYRAPV
IINVVNNQWAISSFQGIAGGENTTFAARAVGYGIPPLRVDGNDFLAVYAATQWAAERARA
NLGPTMIELFSYRAGPHSTSDDPSRYRPADEARQWPLGDPIERLRDHLVSLGEWSEEQHR
AAQEEAIETVRAVGREAEKVGVLGPGAAHTRESMFEDVYKDMPWHLREQRDEQGEA
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atggacgatatgagtagccgcaagtcgaacgcgctcgatctgcatatccccgcgccgcga
gcgcgcccgggcgacaagcccgatttcagcggctggtcgttccctgagcccggcgccacg
ccgaagccggacatcgacgagagcgccgttgagatgcgcgacttcgcctacggcctcatc
cgcgtgctcgacatggaaggcaatgcgctaggtccatggacaccgcacatttccgccgat
gatcttcgccgtggcttgaagaacatgctgctgctgcgtgcttacgacgagcgcatgcac
cgtgctcagcgtcagggcaaaacctcgttctatatgcagtcgctcggtgaagaggccatt
tcgattgcgcaagctatggcgctggcgccggatgacatgtgtttcccatcctatcgtcag
cagggcattctgatcgcgcgcggctatccgctcgtcgacatgatgcaccagatctattcg
aacgcgcgcgatccgatgaagggccgccagctgccggttatgtattcatcgaagaaggac
ggcttcttcaccatctccggcaacctcgccacgcaggtgccgcaagccgtgggttgggcg
atggcgtccgcctattcaaacgatggtcgcatcgccgccgcttggcttggcgaaggttca
accgccgaaggcgattttcacgcagcgatgacgttcgcgaacgtttatcgcgcgccggtt
atcatcaatgtcgtcaacaaccagtgggcgatatcatcgttccaaggcattgccggcggt
gagaacaccaccttcgccgcgcgtgccgtgggctatggcattccgccgctccgcgtcgac
ggaaacgacttcctcgccgtctatgcagcgacgcaatgggccgccgagcgcgcacgcgcc
aatctcggtccgacgatgatcgagctcttcagctatcgcgccggcccgcactcaacctcg
gatgatccctcgcgctatcgcccagccgatgaagcgcgccaatggcccctcggcgatccc
atcgaacgtctgcgcgatcacttggtctcgctcggcgagtggtcggaagagcaacatcgc
gccgcgcaggaagaagcgatcgaaaccgtgcgcgccgtcggccgcgaggccgagaaagtc
ggcgtgcttggcccgggcgccgcacacactcgcgaaagcatgttcgaggacgtctataaa
gatatgccgtggcacctgcgtgagcagcgcgacgaacagggggaagcgtaa
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