Caenorhabditis briggsae (nematode): CBG_11882 Help Entry CBG_11882         CDS       T01054                                  Symbol Cbr-lrp-1 Name (RefSeq) Protein CBR-LRP-1   KO K06233   low density lipoprotein-related protein 2 Organism cbr  Caenorhabditis briggsae (nematode) Brite KEGG Orthology (KO) [BR:cbr00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cbr04131]     CBG_11882 (Cbr-lrp-1) Membrane trafficking [BR:cbr04131]  Endocytosis   Clathrin-mediated endocytosis    Low-density lipoprotein receptor (LDLR) family proteins     CBG_11882 (Cbr-lrp-1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ldl_recept_a Ldl_recept_b FXa_inhibition cEGF DUF5050 EGF_LRP2 SGL Vgb_lyase EGF_CA LDLRAD1_C Motif Other DBs NCBI-GeneID:  8580683 NCBI-ProteinID:  XP_045094694 WormBase:  CBG11882 LinkDB All DBs Position I:294854..317822 Genome browser AA seq 4829 aa AA seqDB search MILRFLIFTALAVTTANSSTRQQAAAASSAFHSIQVDSPPSVRSRIISASVNTASSVCNE NDFRCSDGKCIRAEWKCDGSGDCSDGEDEKDCPHPGCKSDQWQCDTYTWHSVSCIAEYQR CDNITDCADGSDEKDCRELWTSGHTDNLSFKLLPLSTAALRTFSCVPMVVNALISPKNKD SCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPETCEFKKCTANEFQCKNK RCQPRKFRCDYYDDCGDNSDEEECGEYRCPPGKWNCPGTGHCIEQLKLCDGSKDCADGAD EQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLDDRFHRTCSDINECAEFGYCDQLCA NHRPGFTCSCLGDCFTLQMDHGPGKDNLTMRGYCISNNADKMKLFVARREGLYRLNPKNP DEEVKKLASGEFIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYP RCLAVDWITNTLYIIESGSRRIDVSSYDGDRRTVLLADGLTLPLDIALDPLRGEMFFTNQ LKIEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDYQVRKLLVDF EFPPPKHFFLQGNDRRIVAQGMNTVPHPFGLALFDQYLYWTDWTRLGVVQVEKFGSDTKL LWSNTENNVFPMGISAYHPMAQPGPGQSECLAMKIENPCTNADCEGMCILSKDNGGFGVG YKCACPIGQKLVNGKRCIDSIDYLLFSSNKIVRGIFPEIAEKALAEAVLPISPISQRRIG MYFEVECDVHGNSFFYADIMDNTIYRIRPDGEGSAPVLVTHNDGLFSMSFDWISKQLYYV DNIRNSLEVVKIGETGLVQPDELVRRQLLTELRDPVSVVVHPWKGLLFYAEAMRPAAIYK CHIDGTNCQVIRNTTLGRPSEMAIDFEEDRICWGDTLLKTISCMDLDGKNVNTLDTDTPI PVAITILNEYIYYVHQRPYSIRRVHKKNGGGSKIVREFGADERSIFSLKACSHQNQPIPE DSREHPCRASQCTQLCFATPSESDPNTLEAKCACREGFKINADNNHSCQRDKSESIEVLC PNNSTQFLCKNGRCIPKEWKCDGENDCLDESDEVDEKGDKCFHETECAENTIKCRNTKKC IPAQYGCDGDNDCGDYSDEDVKYCKEGQKPVCSAKKFQCDNHRCIPEQWKCDSDNDCGDG SDEKIELCGNATCAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFR CANGRQCVPLRNHCDGQNDCEDGSDEDSCAVSSETCTSDQFQCVSSGLCIPASWKCDGQV DCDDESDEPRFGCTRGRECKADQFKCGNGRCILNNWLCDGENDCGDGSDESAERGCKSPM NTRKCPFEHVPCENDPETCIPLHQLCDGKRHCPGGTDEGGRCGRDLCSADRAGCAFKCHN SPNGPICSCPQGEQCQFLKFLFQLVNKTKCEPENECLDASSCSQHCKDEKHGFTCSCEEG YELDANKRTCKVQDNVKDTRIYVSNRNRIYYSDHKLDNWHTFGAVVENAIALAWDSLTDR IYWSDIREKKILSANRNGTNATVFISDGLDITEGIALDWVGRNLYWVDSSLNTIEVANLE DPKQRTLLVHQNISQPRGIAVDPRKGVMFWTDWGQNPCIERASMDGSDRQIIVKTKIYWP NTIALDLTTNRVYFADSKLDFIDFVNYDGTGRTQVLASSKFVQHPHALAIFEDMMYYSDR RLQKLQVYPKYPNGTTGEYPSHTFSKALGVVAVHPALQPVIKNNPCSNNPCSHLCLLNNK NVGFTFTCKCPMGEKLDGSGKKCVDDAKPFLVIIQKTNVFGVEMDSSSESTWTRRSPTGT PDLAGMVPLSGLGNAFDAAYDALSEEMFILEHTNHAKTLAQITTDSAIYRSTVNGGNKTK MFSSAVPDDAYCLGFDWNGRNLVVGNKVTQTIELIRTQGKQYRSVILSNDQSPTAVVTPV SIAVDADKGYVFWLDRGGGASDAKVARAGLDGSNPLVIASNDLAELDHIALDTTNQRVYF SEAKAGRISSVTYDGQDRHYVLSDGGRQPNGLAFHGDRLFYADSAFDSIEVATILGDSQP PSWTHFKKDVENLANIKVLQPRASSSSHPCHINNGNCDHICIPQMFAQHACSCANGFTKD GQTSCKLFDESFVIVATKTKVTGYPIDESQSKGVAMEPIGGLSITGVDYDFESKTIYVAE ASGINKGITAYTIGESAPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKL DGTYRKILLTTKTETPSSIAVDPVARYLYWADQGQKPSIQRAFLDGSRREVIVSSGIGEP TDLVVDVASRMIYWSDAKLDGIFRVRSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLE KLFRATSKPNQTSLLLSPTTVAASLKDIGDVAVFSSTNQPRASSPCQITDNLRKSPCTQL CFATPGTQTPICACARGVLKGRTCEEPDTYLMFSDGDKIIDAAIEPDVKASRPLKEPFPE ITNLQTFDVDVNLRRVYFVVESPIGVNISWFSMNNAENPRLVFGASKQAHAKEVRHISDM KLDWLTQKIYFTTGRGGKVMVIDAAGEHLSTIASGDWTYALAIDPCSGLLFWSDSGYKTS GGLYEPRIERSNLAGGSRKVIVSESISLPAAITVDFRNQMIYWADVNRLNIEVADYNGEN RKIIASGYRAKSLDLWDRWLYMSDPLSNGVFRIDKESGSGLENVVSNRRIPGALRVFASE SDVRTRNQVCNALTTQLCKNDNGGCDQLCSVIADDVGLAASKVQCSCNDTYELVQEPGKD YPTQCVLRGSSSEPAKECLPPYNFQCGDGSCILLGATCDSKPDCPDASDENPNYCNTRAC PDGYHLCTNRRCIDSAKKCNHIDDCGDGSDELDCPSAVSCAEGTFPCSNGHCINQTKVCD GHNDCHDEQVSDESRATCPNLPIDCRGVKIRCPNTNICIQPADLCDGYDDCGDKADENQL FCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTSGKKICVGDYLFQC DNLKCISRAFICDGEDDCGDGSDEHARHGCGNRTCTDQEFHCASNAKLAQPKYECIPRAW LCDGDVTCAGGEDESTDLCKTEKKECNKGEFRCNNQHCIHASWECDGDNDCLDGSDEHAN CTYSSCQPDFWQCANHKCVPNSWRCDGNDDCEDGSDEKDCPKNSAAGQKTSKCSKSQFQC TSGECIDDAKVCDRNFDCGDRSDESSLCFIDECSLAEKPLCEQKCIDQKIGYKCDCFEGF AIDVSDQKSCHNVNECFEGISGCSQKCDDKIGSYKCACVDGYQLSSDDHSCKRVEMEPEP FFLLANKHYIRKISMDGNKYELAAQGFDNVVSLDIDLTEKKAYLIDQGKLRLLRVNLDEM DSPLSSYETVLRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDRIQQ PKAIAIHPGKGYLFFTEWSLQPYIGRMALDGSPELPDPIFKLAEHDLGWPNAIAIDYFSD RLFWGDAHLNEIGFMDFDGNGRRHIPAQRTSHVSSMVIFDDYLYWADWNLREVVRCDKWT GKNETVLKKTVQLPNDLRIVHPMKQPAYPNPCGDNNGGCSHLCLIGAGGNGYTCSCPDQF VLLPDQKTCEPNCTDRQFACGGDDAKCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVG EFQCTNHNCTRPFQICDGNDDCGDGTDEQNCDKACDPWMFKCAATGRCIPKRFTCDGDDD CGDRSDEADSLCMSPDRNCTAEEFRCNNNKCIAKAWRCDNDDDCGDGSDETPECAQIECK KGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCATTGKCIPKRWMC DTENDCGDNSDELDASCGGTTRPCSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTL RRCTAGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANSVCIPR KFMCDGDNDCGDNSDETSTECRMAQCDPPLRFRCAHSRLCLNILQLCNGMPDCGPNDFSD EHLSMCSSFSEGSDCASDQFKCSNGKCVNATLACDRKDDCGDASDEIGCCKFFQTSQNFG QFRNIPIFLSLEFRVEIATKHGGKTSCEAFGNNGGCKQICTDVRDGFYCHCRDGFRPDPQ SPKECIDIDECAGNNTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVM IGADSSLVQLSLHGTGTNRHAAAKANDEDSDIIGIAFDPRKELMYWIDGSERTIYRSAIS NGNQSHEGQKLDIDFAGMGVVPTAIAVDYTTGNLFVAAVSEDVENGLVTARKKRMSEPID NQNTGFIFLALPDGRYVKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTH RQIIVKDLVFSPTSMAIDEGKNNRIYWVDPKYRRVDAVNIDGTDRTTVVHDKHIPYAVDV FENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRVVSGCERAQ CSHLCVTLPSSGFACLCPEGIVPQMDGSCATQHVEALTMPKQCKCTNGGKCRLDGSCECT SDFEGDLCDKESSVSRRIIGTLSENFFTVLLYILAFLAAFGLIGFIGLNVYKRRQLLFKK NEAADGSVSFHGNVISFSNPVLESKQDAPGSEFSMQQMTSMHDDSTTFTNPVYDLEDVDM SSPRSDNRPSTSSAMSPNGPSTSSASSSFVPPTFNQDEIEVKTSDQVIVPKVEISKPPIP ARPNKKEKKEETLRVDNPLYDPDSEVSDV NT seq 14490 nt NT seq  +upstreamnt  +downstreamnt atgattctgaggtttctcatattcacagcattggctgtgacaacagccaattctagtaca cgacagcaggcggcagctgcttcgtcggcttttcattctattcaagtcgattctccacca tcagtgcgttctcgaataatctccgcgtctgtgaatacggcgtcttcagtttgcaacgaa aacgatttccgatgttctgatggaaaatgtattcgtgccgaatggaagtgcgatggatct ggtgattgctcagatggagaagacgagaaggattgtccacatcctggctgcaaatccgat caatggcagtgtgacacctacacgtggcacagtgtctcctgtatcgccgaatatcagaga tgtgataatatcacggattgtgccgacggttctgatgaaaaggattgccgtgagttatgg acatccggacacaccgacaatctctcatttaagctgcttccactgtcgactgcagctctc cgaacgttttcatgtgtgccgatggtcgtcaatgctttgatatcaccaaaaaataaggac tcgtgctctcgtaatcacaccgcctgcttccaatatcaattccgttgtgctgacaagacg caatgcattcaaaagtcttgggtttgcgatggctccaaggattgtgcagatggatccgat gagccagagacgtgtgagttcaaaaagtgcacagccaacgagtttcaatgtaaaaacaaa cgttgtcaaccgcgaaagttccgttgtgactactatgacgattgtggtgataattctgat gaggaggagtgtggagaatacagatgtccacctggaaaatggaattgtccgggtactgga cactgtattgagcaattgaaactgtgcgatggatcaaaggattgtgcagatggagctgat gagcaacaatgttcccaaaatctctgcccatccctcggttgccaagccggatgtcatcca tcccctcacggaggagaatgcacctgtccatctggatacaaactcgacgaccgtttccat cgcacttgttccgatatcaatgagtgtgctgagtttggctactgtgaccagctatgcgcg aaccatcgccccggcttcacatgctcttgtcttggagactgtttcacacttcaaatggat catggaccaggaaaggataatctgacgatgagaggttactgtatctcgaataatgctgat aaaatgaaattgttcgtggcgagaagagagggtctgtatcgattgaatccaaagaatcca gatgaagaggttaagaagttggcttctggagagttcatttatggaattgatttcgattat ggagatcgaaaaatcttctggactgatcgattggcacactcggcgtttagtgctgacgtc gatgatgaaggagaaatttcacagattaagaagctcagcctcaaatctcttgtctatccc cgctgcttggccgttgactggattaccaacactttgtatattattgaatctggatccaga agaatcgacgtctcctcatatgatggagatcggagaactgttcttcttgccgatggactc actcttccattggatattgctctggatccacttagaggagaaatgttcttcacaaatcag ctgaaaatcgaagctgccgcaatggatggaacgaatcgtcgcactttggtcaacactcac acccatcaagtgtccggaatcgttgtcgatatcactgctaagcgagtctactgggttgat cccaaagttgatcgattggaatctattgattatcaagtaagaaaacttctagtcgatttt gaattcccgccacctaaacacttttttctccagggaaacgaccgtcgaattgttgcccaa ggcatgaacacagttcctcatccattcggtctcgctctcttcgatcaatatctctactgg accgactggacccgcctcggcgttgttcaagtcgagaaatttggatccgacactaaactt ctctggagcaacactgagaacaacgtcttcccaatgggaatctccgcgtatcacccgatg gctcaacccggacccggacaatccgagtgtctcgccatgaagattgagaatccatgtacc aacgcggattgcgaaggaatgtgtatcctgtcgaaggataatggaggattcggtgttgga tacaagtgtgcgtgtcctattgggcagaagctggttaatggaaagagatgtattgattct attgattatttgttgttctccagcaacaagatcgtcagaggtatcttcccagaaatcgct gaaaaggctttggccgaagctgttcttccaatctcgccaatttctcaaagaagaatcgga atgtattttgaagtggagtgcgatgttcatggcaactctttcttctatgctgatatcatg gataacactatttatagaatccgccccgatggagaaggatcagcgccagtgctagtcact cataacgatggactcttctcaatgtcctttgactggattagcaagcaattgtactatgta gacaatattagaaacagtttggaggttgtgaaaattggagaaactggattggttcaaccg gatgagttggttagaagacaactgctcacagagctcagagatccagtatcagtggttgtg catccatggaagggattgttgttctatgcagaggcaatgagaccagctgctatctataaa tgccacatcgacggaaccaactgtcaagtcatccggaataccaccctcggacgcccatca gaaatggccattgactttgaagaggaccgcatctgctggggagacaccctactgaagacc atctcttgtatggatctagatggaaaaaatgtgaacactctggataccgacaccccaatt ccagtggctattactattctgaatgagtacatttattacgttcaccaacgtccttattcc atcagaagagttcacaagaagaatggaggaggaagcaagattgtgcgagagtttggagct gatgaacgctccatcttctcactcaaagcctgctctcaccaaaaccaaccgatcccagag gactctcgcgagcacccatgccgtgcctcccaatgcacacagctctgctttgcgacacct tcagaatccgacccgaacactctcgaagccaaatgcgcgtgtcgtgaaggattcaagatc aacgcggacaacaatcacagctgccaacgtgacaaatcagaaagcatcgaggtcttgtgc ccaaacaactcaactcaattcctttgcaagaatggaagatgtattccaaaagaatggaag tgcgacggggagaatgattgtttggatgagtcagatgaagttgacgagaaaggagacaag tgtttccatgagacagaatgcgccgagaacaccatcaagtgtcgaaacaccaaaaagtgc atcccagctcaatacggatgcgatggagataacgattgtggagactattctgatgaagat gtcaagtactgcaaagagggacagaagccagtgtgttccgctaagaaattccaatgcgac aaccacagatgcattccggagcaatggaaatgtgacagtgacaatgattgtggagatgga tcagatgagaagatcgagctctgtgggaatgccacttgtgcagcgaatcaattctcctgc gccaatggaagatgtattccaatctattggctttgtgatggagataatgattgttacgat ggaactgatgaagataaagaacgctgtccaccagttcaatgctcggctcttcagttcaga tgcgccaatggtcgtcagtgtgttcctttgagaaatcattgcgatggacagaacgattgt gaagatggctctgacgaagactcgtgtgcagtctcctctgaaacctgtacatcggaccaa ttccaatgtgtgtcttctggattatgcattccggcgtcgtggaagtgtgatgggcaagtg gattgtgatgatgagtccgatgagccaagattcggatgtactaggggaagagagtgcaaa gccgatcagttcaagtgcggaaatggaagatgtattctgaataactggctgtgcgacggc gaaaacgactgcggcgatggctccgacgagtctgccgaacgtggatgcaagtctccaatg aacacaaggaagtgtccattcgaacatgtcccctgcgagaatgatccagaaacgtgcatc cctctacaccaactctgtgatggaaagagacattgtccaggtggaactgacgaaggagga cggtgtggaagagacttgtgctccgcagaccgagccggatgcgcattcaagtgccataac agtccgaatggtccgatttgcagttgtccgcaaggagaacagtgtcagtttttgaaattt ctttttcagctcgtcaacaaaaccaaatgcgaacctgaaaacgagtgtctcgatgctagc agctgctcccaacactgcaaagatgagaagcacggattcacctgctcctgtgaagaagga tacgaactggatgccaacaagagaacttgcaaggttcaggacaatgtcaaagatactcga atctacgtttcaaaccggaatcgtatctactatagtgaccataagcttgacaattggcac acttttggagcagtggtggagaatgcgattgctcttgcttgggatagtcttacggatcga atctattggtcagatatccgagagaaaaagattctatctgccaatcgaaatggaacgaat gcaactgttttcatttctgatggtttggatatcactgaaggaatcgcgttggattgggtt ggaagaaatctgtactgggttgactcctccctcaacacaatcgaggttgccaacttggaa gatccaaaacagagaacactgctggtccatcagaacatcagtcagccacgtggtatcgct gttgatccacggaaaggagtcatgttctggacagattggggacagaatccatgcatcgag agagcttctatggatggatcggatcgtcagatcattgtcaaaaccaagatctactggcct aacactattgctctagacttgactaccaaccgagtctactttgcggattccaaacttgac tttatcgattttgtcaactacgatggaacaggaagaactcaagttctcgcctcctcaaaa ttcgttcagcatccacacgcgttggcaatctttgaggacatgatgtactactcagatcga agacttcagaagttgcaagtgtatccaaagtatccaaatgggaccaccggagagtatcca agtcatacattcagtaaggctttgggagtggtcgctgtccatccagcacttcaaccagtg atcaagaacaatccgtgctccaacaacccatgtagtcatttgtgtttgttgaataataag aatgtgggttttaccttcacttgcaaatgtccaatgggagaaaaattggatggatctgga aagaagtgtgtcgacgatgctaagccattccttgtcatcatccagaaaactaacgtcttc ggagtagagatggattcgtcttccgagtcgacatggactagaagaagcccaaccggaacc ccagatcttgctggcatggtcccactttccggtcttggaaacgccttcgacgccgcctat gacgctctcagcgaagagatgttcattttggagcacaccaaccacgccaagactctagct caaatcacaacggactcggctatctaccgtagtactgtgaacggtggaaataagacaaaa atgttctcatcggcggttccggatgatgcttattgtcttggattcgattggaacggacga aacttggtcgtcggaaacaaggtcactcaaaccatcgaattgatccgaactcaaggaaaa caatatcgatccgtgattctttccaacgatcaatcgccaactgcagtggtgacacctgtc tcgattgctgttgatgctgataagggatacgttttctggctggatcgaggaggcggtgct tcggatgcaaaggtcgcacgagctggattggatggaagcaacccgttggtgattgctagc aatgatttggcagagttggatcatattgcattggatactaccaatcagagagtctacttc tcggaagccaaggctggaaggatctcctctgttacctacgatggtcaagaccgtcactac gttctcagcgacggcggccgccaaccaaatggactcgctttccacggagatcgcctattc tacgccgactctgctttcgattccatcgaagtcgctacaatcctcggagactcccaacca ccatcttggacccatttcaaaaaggatgttgagaatcttgccaacatcaaggtgctccaa ccaagagcgtcttctagcagccatccatgtcatatcaataacggaaactgtgatcatatc tgcatcccacaaatgttcgctcaacacgcttgctcatgtgcgaacggattcacaaaggat ggtcagacatcttgtaaactcttcgatgaatcatttgtcattgttgctaccaagacaaag gtgaccggatacccaatcgatgagtcccaatccaagggtgttgctatggaaccaatcgga ggtctatccatcactggagttgattatgatttcgaatcaaagaccatctacgtggccgaa gcttctggaatcaacaagggaatcaccgcctataccatcggagagtctgcaccaagagca gtgattcgtgactcgatcggatcattgacaatcaagagtttggctattgactggatcaat tacaacatgtacttcatcaaccacgacgctgaacgaaccaacatcgaggtctccaaacta gatggaacctatcgcaagattttgttaaccaccaagacagagactccatcttctatcgct gtggatccagttgcaagatatttgtattgggcagatcaaggacagaaaccaagcattcaa cgagcattcttggatggatcccgtcgcgaggtcattgtttcttctgggatcggagagcca actgatctagtagtggatgttgccagcagaatgatctattggtcagatgccaaactggat ggaatcttccgtgtcagaagtacaggtggaacgccagaacttgttcgatccgatatcgca tctgctgccggagtggctcttcacggacagaacatgtactggacagacaacagacttgag aagctcttccgagccacctcgaagcctaaccagacttcccttctcttgtctccaactacc gttgccgcatcacttaaggatattggtgacgtggcagtgttctcgtcaaccaatcaaccg agagccagcagtccatgccagatcactgataaccttcggaagagcccttgtactcaactg tgcttcgccacacctggaacccagacaccaatctgtgcatgtgccagaggagtgttgaag ggaagaacttgtgaagagccagacacttatctcatgttctctgatggagataagatcatc gacgccgcaatcgaaccagatgtgaaggcatctcgaccactcaaggaaccattcccagag atcacaaatctccagacttttgatgtggatgtcaacctgagaagagtgtattttgtagtc gaatccccgattggagtgaacatctcctggttctcgatgaacaacgctgagaatccaaga ctggtattcggtgctagcaaacaggcacacgccaaggaagttcgccatatttctgatatg aagttggattggttgactcaaaagatctatttcacaactggaagaggtggaaaggttatg gttattgacgcagctggtgaacacttgtcgacgattgcttctggagactggacatacgct cttgctatcgatccatgttctggccttcttttctggtctgattccggatacaagactagc ggaggactctacgagccaagaatcgaaagatccaacttggcaggtggaagtcggaaggtc attgtatccgagtcgatttccctcccagctgctatcaccgtcgacttcagaaaccagatg atctactgggcagatgtcaacagactcaacatcgaagtcgccgattacaatggagagaac cgaaagatcattgcttcaggatatcgtgcaaagtcccttgatctctgggatcgttggctc tacatgagtgatccattaagtaatggagtcttcagaatcgataaggaatctggatctgga ttggagaacgtcgtgagcaatagaagaatcccgggagccctccgagtgttcgctagtgaa tctgacgtcagaactcgtaaccaagtttgcaatgccctaaccactcaactttgcaagaat gacaatggaggatgtgatcagttgtgctctgtgatcgccgacgatgttggattggcagcc agtaaggttcaatgctcgtgtaacgatacttatgaattggtacaagagcctggaaaggac tatccaactcaatgtgtgctccgtgggagctcttcggagccagcaaaggaatgtctgcca ccatacaacttccaatgtggagatggatcatgtattcttttgggagccacttgtgattcc aagccagattgtccagatgcttcagacgagaatccaaactactgtaacactcgtgcttgc ccagatggttaccacctgtgtaccaatcgccgttgcattgactcagccaaaaagtgcaat cacattgacgattgtggagatggatctgatgaactcgactgcccatcagccgtctcatgt gcggaaggaacattcccttgctcaaatggtcattgtatcaaccagacgaaggtttgtgat ggtcacaatgattgtcacgatgagcaagtctccgatgagtcgcgtgccacgtgtccgaat cttccgattgattgtcgtggagtcaagattcgatgcccaaataccaacatttgcattcaa ccagccgatctttgtgatggttacgatgattgtggagataaggctgacgaaaatcaattg ttctgtatgaaccaacaatgtgcccaacattacgtccgttgcccatccggaagatgtatc ccagaaacgtggcagtgtgatggagacaatgattgctcagatggctgggatgagactcac actaactgtaccgacacttctggtaagaagatctgtgtcggtgactacttgttccagtgc gacaatctcaagtgcatctcccgtgcgttcatttgcgatggagaggatgattgtggagat ggatccgatgagcatgccagacacggatgcggtaaccgaacctgcaccgatcaagaattc cattgcgcatcgaatgcaaaactagctcaaccaaaatacgagtgtatccccagagcctgg ctttgcgacggtgacgtcacctgtgctggaggagaggacgagtctacagatctttgtaaa accgagaagaaggagtgcaacaagggagaattcagatgcaacaaccaacactgtattcac gcgtcctgggagtgcgatggagataacgactgcctcgatggctccgatgagcacgccaat tgcacgtattcctcctgccagccagatttctggcaatgtgccaatcataaatgtgtgccc aactcgtggagatgtgatggaaatgatgattgtgaggatggatcagatgaaaaggactgt ccaaagaattcagcagcaggacagaagacgtcgaaatgctccaagagccaattccaatgc acttccggagaatgtatcgatgatgcgaaggtgtgcgatagaaactttgattgtggagac cgttcggatgagagctcgctttgcttcattgacgagtgctctcttgctgagaaaccactt tgcgagcagaaatgcattgatcagaagatcggatacaagtgtgattgcttcgaaggattc gccattgatgtttccgatcagaagagttgtcacaatgttaatgagtgcttcgaaggaatc tcgggatgcagtcagaaatgcgacgacaagatcggatcctacaaatgcgcgtgcgtggac ggctaccaactttctagcgacgatcatagctgtaaacgtgtcgaaatggaaccagaacca ttcttccttctggccaacaaacactacatcagaaagatctctatggatggaaacaaatac gaactggctgcacaaggatttgataatgttgtctcccttgatatcgatcttactgagaag aaggcgtatcttattgatcaaggaaagctccgacttctgcgagtcaacttggatgaaatg gattctccactatctagctatgaaactgtcctaagacataatgtctatggaaccgaagga atcgctgtggactgggttggacggaagctctacatgcttaatcgtcaagagagatcaatt cgagtttgtgaacttgacggtagattctgcaaaactctcattcgagacagaatccaacaa ccaaaggcaattgctatccatccaggaaagggatacttgttcttcacagaatggtctctc caaccatacatcggaagaatggccctcgacggttctccagagcttccagatccaatcttc aaattggcagaacatgatctaggatggcctaatgcgattgcaatcgactatttctcggat cgcctcttctggggagatgctcatctgaatgagatcggattcatggactttgatggaaac ggaagacgtcatataccagctcaacgtaccagccacgtctcgtccatggtgatcttcgac gactacctgtactgggctgattggaatttgagagaagttgtcagatgtgataagtggact ggaaagaacgagactgtgctcaagaagactgtccaacttccgaatgacttgagaatcgtg cacccgatgaaacagccagcctaccccaacccatgtggagacaacaacggaggatgttct catctttgcttgattggagctggcggaaatggatacacttgctcgtgtccagatcaattc gtgcttcttcccgatcagaagacttgtgaaccaaactgcacggatcgtcagtttgcctgc ggtggcgacgatgccaaatgcattccaaaactgtggtattgcgatggagagccagattgt agagacggatcagatgagcctggagagagcatctgtggacagcgaatttgtccagtcgga gagttccagtgcaccaatcacaactgcacccgcccattccaaatctgcgatggaaatgat gattgtggagatggaactgatgagcagaactgtgacaaggcttgtgatccatggatgttc aagtgtgcggcaactgggagatgcattccaaagagattcacttgtgatggagatgatgat tgtggtgatagatcagacgaggctgattccctttgtatgtcaccggaccgaaactgcaca gctgaggagttcagatgcaacaataacaagtgcatcgccaaggcgtggagatgtgataac gatgatgattgtggagatggatctgacgagactccagaatgcgctcaaatcgaatgcaag aagggatggactcgctgctcatcctcctacagatgcatccccaactgggcattctgtaat ggtcaagacgattgcagagacaattctgacgaagacaaacaacgctgtccaacttgcgac gatgttggagagttccgatgcgccacgactggaaaatgtattccgaaacgttggatgtgt gataccgagaatgattgtggagacaattcagacgagctggacgcctcctgtggtggaact actcgcccatgctccgaatctgagttcagatgtaacgatgggaagtgtattccaggaagc aaggtttgcgatggaaccattcagtgtagcgatggactcgatgaatctcaatgtaccctt cgaagatgtacggctggtcatagacagtgcgatgatggtacttgtattgctgagcataag tggtgtgatagaaagaaggactgtccgaatgcagctgatgaattgcattgtgaagatgtg tctcgccgaacatgctctcctttcgaattcgaatgtgccaactccgtctgcatcccacgc aaattcatgtgcgacggtgacaacgactgcggagacaactctgacgagacatccaccgaa tgccgaatggctcaatgcgatcctccacttcgtttccgctgtgctcactctcgtctctgc ttgaacatccttcaactgtgcaatggaatgcccgattgtggaccaaatgacttctcagat gagcatttgtcaatgtgctctagcttctcggaaggatcggattgtgcatcggatcagttc aagtgttccaatggaaaatgtgtgaatgccacgttggcttgtgataggaaggatgattgt ggtgatgcgtcggatgagatcggatgttgtaagttttttcaaacttcccaaaattttgga caatttcgaaacattccaatttttttaagtttggaattcagagttgaaatcgcgaccaaa cacggaggcaagacttcctgcgaagcattcgggaacaacgggggctgcaaacaaatctgc acagatgttcgcgatggattctactgtcactgccgagatggcttccgtcccgatccacaa agtcctaaggaatgtatcgacatcgatgaatgtgctggaaacaacacttgcacccaactc tgcctcaacaccaaaggatcctatctatgcagatgtcacgaggattacgagaataatgta gtcgttggatcaatgactggaaaggattgtcgagcgaagggagatgctgcgaacgtcatg atcggagcggattcttctcttgtacaactgtcacttcatggtactggaaccaatcgtcac gctgccgcaaaggccaatgatgaggatagcgatatcattggaattgcatttgatccaaga aaagagttgatgtattggattgatggaagtgaaaggacaatctaccgtagtgcaatttcc aatggaaatcagagtcatgaaggacaaaaacttgatattgatttcgcaggaatgggagta gttccaaccgccattgctgtcgactacaccactggcaacctcttcgtggctgctgtatct gaagacgtggagaatggtttggtgacggcgagaaagaaaagaatgtcggaaccaattgac aatcagaacactggattcatctttttggcacttccggatgggagatacgtgaaaaagatc gtcgctggacatcttcaacagccaactgctctgatcacagcaccatcagcaggtcgtatc tgctactcggatgcaggtctccatgcaaagattgagtgtgctgatatggatggaacccat cggcagattattgtcaaggatcttgtattctccccaacctcgatggctatcgacgaagga aagaacaacagaatctattgggtggatcccaagtatcgaagagttgacgcagtgaacatt gatggaactgataggactactgtagttcacgacaagcacattccttatgcagttgacgtc ttcgaaaatcacatttactggctgagcagagaatcaaagacgctctacgttcaggataag ttcggaagaggaagagtgtcagtgttggcgtcggatcttgaagatgggcatactgtaaga gtcagtcagaaatatgcaaaggacacacaacgagtggtatctggatgtgagcgtgctcaa tgctctcatctctgcgtaaccctgccatctagtggattcgcttgtctctgcccagaagga atcgtcccgcaaatggatggatcatgtgcaactcaacatgtcgaagcactcacgatgcct aagcagtgtaaatgcacaaatggaggaaagtgtcgtttggatggatcctgtgagtgtaca tcggactttgaaggagacttgtgcgataaggaaagtagtgttagccgacgaatcattgga acactttctgagaacttcttcaccgttctattatacattttggcattcttggctgcattc ggattgattggattcattggattaaatgtttataagcgacgacagctgttattcaaaaag aatgaggcagctgatggaagtgtgtcgttccatggaaatgtcatttcgtttagtaatcca gtgttggagtcgaaacaggatgcccccggaagcgagtttagtatgcaacaaatgacatcg atgcacgatgattcgacaaccttcacaaatccagtatacgatctagaagacgtcgatatg tcatctccaagatctgataatcgaccatccacgtcatcagccatgtcaccaaatggacca tctacgtcttctgcttcttcttcttttgtaccacctacattcaaccaagatgagattgaa gtgaagacatcggatcaagttattgttccaaaagtggaaatctcgaaacctccaattccg gcccgacccaacaaaaaggagaaaaaagaggagacacttcgtgtcgacaatcccctgtac gatccggattctgaagtttccgacgtctaa

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