Caenorhabditis briggsae (nematode): CBG_19042 Help Entry CBG_19042         CDS       T01054                                  Symbol Cbr-lipl-6 Name (RefSeq) Protein CBR-LIPL-6   KO K04962   ryanodine receptor 2 Organism cbr  Caenorhabditis briggsae (nematode) Brite KEGG Orthology (KO) [BR:cbr00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cbr04040]     CBG_19042 (Cbr-lipl-6)    04990 Domain-containing proteins not elsewhere classified [BR:cbr04990]     CBG_19042 (Cbr-lipl-6) Ion channels [BR:cbr04040]  Voltage-gated cation channels   Ryanodine receptor    CBG_19042 (Cbr-lipl-6) Domain-containing proteins not elsewhere classified [BR:cbr04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    CBG_19042 (Cbr-lipl-6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans RR_TM4-6 Abhydro_lipase Abhydrolase_1 EF-hand_7 EF-hand_5 EF-hand_1 EF-hand_6 Hydrolase_4 EF-hand_8 Motif Other DBs NCBI-GeneID:  8579340 NCBI-ProteinID:  XP_045096649 WormBase:  CBG19042 LinkDB All DBs Position V:complement(12552091..12582239) Genome browser AA seq 6513 aa AA seqDB search MKLIILILLLILYSLCDEITTSTSEEDTDMTATPSTTTPLLSTAQNPGLPKTSILPIALK SPVPTFSFSSLSTNDWLSSMPTVQTLLPPPIAPTTMEVPDKETFGFNSLTPLWTIPTKTP VISPINDSPIKPMQDVFPPFPTMPTLPTLAPFTFPTLPPPTTMKPLNITIDPEAIMDVPE IIAHWGYPVETHKVVTADGYILTLHRIPHGKSKHIAVTNSSFPNTKKLLEMRPRNPHPKC LNRSSFCNTDFFVRLRFGYSICRDRYIFADQGYDVWLGNMRGNTYSKQHVRMTSSDRRFW KFSWEEMARYDLPAMINYVLKNTRQSNLYYVGHSQGALTMFAKMSEDPEMSTKVRKFFAL APVARMSHVKGLFHDLGQIYEQYNLVYQVFGDGEFLTNNIFTKLLTDIFCDQAVNNPLCE NFIFAVSGPNSNQFNNSRIGIYLAHNPAGTSSRNMLHFAQMVKTKRMSRFDFGKDLNSKI YGAPLPPEYDIRRINSSIYLFYSDFDWLANPKDVEGFLIPMLPTRSLKKATKLRDFNHND FLWGMRARKEIYEKIINTIKLDQRRVKLQNSMDRFFEKEVNEDDEETEYRQWPFYTVFRS KSTTIREISERNETEPRLGVHLFSFCSKKKIETSINLKHPHNFPFVLSCSSFFFFFLAFP LWYHLHFVSFLTDEEQGGGEQDDVSFLRTSSSVRSEFYEILLSFSLEIRCNKKIVSERCC FIVTQREFFCPLGKKYAVNSKKSEASSFESYSVPFRLLSSSPLASFCAFISRPPSNFLSS TTHIQPINVFLGTPTEELTLSDFQTSHYPHQRVLLVFLITLSSIFSSSNFYRIYSKYVIL YDNTSLYYIDIAEIVSSMFKVPLFKFSANSRRTFQKSSFVRPLFPVDDSDLSLENKQGSC FCRFDLASRLSFSFHLHPRICYVAHMAFCRPGPAYCFFVVFFLLADYSLFFVLMVTLQFS DKETPLFTLEVCSRQQNHRTRQKTAHKRKNTRYTTQYIHDHNYVTKGDIVCLSCVASHNR DGVLGSERVCLCTEGFGNRMCTLENVSDKDIPPDIAMCMLYIDNALSMRALQEMMSADSD HKSASGAGGHKTLLYGHAVQLKHVQSEMYLACLSSCSSNDKLAFDVGVQETNEGEACWWT IHPASKQRSEGEKVRVGDDVILVSVATERYLHMAYSKGYMVIASFHQTLWNIQSVSSGSM RTRNMGFLFGNDVLRLFHGNDECLTIPENWSEHPQHKSSSKKSENYFSMVIYEGGAAVTQ ARSLWRVELVRMKWHGALVGWEQVFRIKHITSGRYLGVLDNAVQLYHKEKADFELTAFVM CQNKDPKKQMLDEKEEEGMGNATIRYGETNAFIQHVKTQLWLSYQTSEVTKKGLGKVEEK KAVALKDGHMDDCYTFFMALEEESKSARVIRKCSSVLNKFLKGIDALQLEGNQSTDWTRV DLNEVLKLMEDLIEYFAQPNEEQDFEEKQNHLRALRSRQDLFQEEGVLNMILDTIDKFSQ MEALPDFAGLIGEETHIKWEQISTYLYLLVAAMIKGNHYNCAQFASAQRLDWLFGRLSNP QSAEGILDVLYCVLTESPEALNMINEGHIRSVISLLEKVGRDPKVLDVLSSLCEGNGMAV RSSQNLITQYLLPGKDLLLQTSMRDHVSSMMPNVMLGVVDGSALFRKWYFEAEVEHIETM TKQTPYLRIGWANSVGFKPFPGSGDKWGCNGVGDDFYSYGFDGKSMFFGGKSRIVGHKLL EKGDVIGCSIDLTIPEIRFSVNGSYMSGSFKKFNTDGYFFPVMSLSAKVSCRFILGGNQG RLRYGPPTGFSAVVEAVNGELGITDCLSFGDLGKNIFCGPQTIFNNLEPFIPTPIDVSTT QLTHHAMEMHQKYAENLHELWAMRKIELGWSYGETRSETSRKHPCLTRFELLPETEKKYN IMLALTTMKTIEALGYHLITDDPPCRLRAVRLAQNFQQSNGYKPGPLDTHEIQLPVELQP LTEALARNTHNIWAKEKIKRGWTFGLSEHVDATQKRSPHLVPYEQVDERIKQANRESAAE NIRALQLFGIFLEPPAHEHDEIAEKELRARKDNTRTYRAEATYAVNGGKWYFEFEILTAG YMKIGWMDIGSTPEIQLGADDRSYAFDGYLGRKWHQGAETYGKEWKIGDVVGCFLDLNDR TISFSLNGELLLDPSGSEMAFDNVVCGDGLVPAMTLGSGQRGRLNFGQQSNSLKFFTTCG LQEGYEPFCVNMYRTMPMWFAKQLPRFEDISTLKSGSILEVTRIPATGNSPPCLKILQKV TISEGGPSEKAKMEYIRLSLPVKCNDTFVKNKDKEAIRRQLQDYKPRSQSVVSQIRAPGI PKEFDDNKEKKGFLRSMLGSKDSHESDDDRNRSRTTSKQPSIEGDEPPAVRYVISYFRLL FSFIFSTRSRYSQRRRVLTLMNFGMYSFDESILTWLHVNEEDNHKWQDVLRRSLLELPHE ERQIAEEHMRDLNDRHAEKPKKGGILSRLRDSSNTRKNFRDSDRRKEDKAAALRQMKSNS RSFDAGSLDTSTLPTGQKDVLDPIWVLQDQFHEEDTVSGEKQAPHQSLSFLAKLSYNLSL SPYLPKTFSSLSNAAWYSKTDVKFEFSASSEMPLSGPGRQLTIKRGSVKKGKKGKKAEIA LEKAMEREKKGSIIPMEAQLDVLQEGDAHALVALKDKVDEYYYGVRIFPGQDTSQVWVGW VTTQYHYYNVHFDGNQGVRKCRFSEADHHGTTVDSVQSQNCYMVNVSELLEKTADVANTK VSGTLIGCIIDTSIGELSFQVGTTDTGVKFKLEPGAMLFPAAFVTPTATDILQFELGRIK YTFPLSAAMFKSCEKSLVPFCPPRLTVEQIESVYWARVPNETLRTTALKLSEVRENEGQC WGEGVARGRSVQRKGGQMGESERQVRRRRTTVLLLFSGWSVLCNDPVRIMSVYIPEKDQS LDILEMIEMPDMLEFHRQTLNLYCKLASHGNHKVAHTLCQHIDEDQIMYAIKSHYLSGPM RQGFHDLLIGIHLMSHTAARNSMAKEYVIPLVPQLQIKNVLDPDSESRYPQITGQSVSML SQMAAEPVKKHISREEEMKLLPPSVDFDALKKHVMESLQSATHHAVMNCRDLIGGDNTNH FEPLFKLFDQLLVIGLINDEELECLLRLIHPQAFDESYKNGTTQKGLTQLELAEPVKLQL VSILDHLCDIQLRYRIESLVAFTEGFVGELQSDQCKRYMEIKQTDMPPAEAAKKTKEFRC PPKEQMFRLLMCKVKEERDPEFMEEDADVDQCPMAESLQQQLRDFCELLVGKIGNAKEGE SEDQLALIESEEGSWVDSFARIVVKVPPPLEEEGMEMQKKGTQNFREIIVTMLREWAQAD FIESKDLIRSMFKLLLRQYSGIREIRDAMSQAYVFHERNAADVTDFIVYLIQIRELLTVQ FEHTEEAILKRGLWKLMNNRIFFQHPDLMRLLSVHENVMSIMMNILTAQQGTVEHEGDEV KEKAPIKDASEMVVACSRFLCYFCRTSRQNQKAMFEHLSFLLDNATMLLARPSLRGSVPL DVAYSSFMDNNELALALKEEELDKVAVYLSRCGLQPNSELITKGYPDIGWDPVEGERYID FLRFCVWINGENVEENANLVIRLLIRRPECLGVALKGEGQGLFSAFKEAIALSEDIRLLE NDSHPSMLTSGLLGENPTYPSKEIEGEDYIDLGAATLDFYSSLVDLLAKCAPDPMAIQAG KGDSLRARAILRSLISLDDLGQILALRFTIPNLAAPSIEAVRRANAVQASHTQKAVMAHT FAMVASLASEVSNTRRSQTFTSGANLARRGFELINSHLFPFLTPSLSRLPCVEEVDSDDS KSSDYASVHTSFSSGNELFAPKSEKQKAELQLLNEKKYPIVQRRRSSRYNPIDNTGPLPG LLPNHKGSVLLFLDRVYGIDQQDMLFHFLEQSFLPDLRAATMMDSPRALESDTALALNRY LCNSVLPLLTNHSHFFSDAEHHSALLDATLHTVYRMNRLKSLTKNQRDAVSDFLVAITRE LPPGMMIKLLKKVINDILTMNDMNVLVPLRLITLHYERCGKYYGSGNHYGVASEQEKRLS MLLFDAIFDTLGSRPYDPELFGKALPCMTAIGSAISPDYSLTSGLEDVRNKRCPLVYKNF VFQKREEEGAWIPRTVDVSRCEINRDLEKMTELFAEHFHDSWASRKLEKGWVHGGLYSRA NFTHPRLKPFALLKDFLILSFQEKSFYKERCSECLKALMAWSYSFDMVDRDANDRASAAR TLSGTSISNFAPKPIDLSSMTLEKDMVNAAEKMAEHSHLIWAKKVMNDLNTKGGFMPIPL VPWDLLTDFERRKDRFRASEILKFLQYHGYHVNCPKDEQSQNDRMKSEGERSSVEKRFAY NLLEKLITYLEQASLKMKSVKPSQELTRRNSFKKEGQDVKFFEKVVLPLMHAYFNAHKNY FLEGSSIVQTGTASNKEKEMVANLFCRLAALLRIKNRAFGSVAKITVKCLQGLTQALDLR TLVKVNSDIVRTSLLTFFNNCADDLYAAVNELKDGGQYSLIRGQALKSWNSFEFANQMIV PVLTTMFAHLARNHFGTDLLLDDIQAACYKILDSLYMVTGLNSSISHRKFISSESEKHRP GLGQCLAAFASCFPVAFLEPEFNKSNKFSVLAKTQDQSVQVQEMLQNLSTHIPHLEKLLT DLETVANNNTMYSDVPNVYDVDLPLMCSYMAHWFNVGPDGKRDKDDQRASVIQTTSVSCD HINRIFNALLKMIRNHVGIENAPWLCRVNCNFIIFAVQIIQNVTSDPVREFVLPIAERLR RMSEKAYKEEEHMRTHPDDADEGTVAEVITTERSNSTSFNSRTTLASSYTDLHRAQWLKS PTWETDGVYENVAVIFRIWSQSQHFKREELNYVAQFEEDAAAMGGGDMKTGKAAIAERKK KRREGQVSSRGSQKIRISKKKRSKTIIIQDKMKEYFDRNGRPIVSFDTTEKPFVEQICCV SSSDYFDHSIKKDKHAASIVIACLKRLLPVGLNVFGGRELDIVQQSKEKFIQKETEEKIR EFIKGLLEIPVKTDPTDKNAWQLSLYRKIGKSQMRGKDEMSQEAVIEKIFNMGQVSAILH VITRTKDRRRRAHHRWKYNRKQHLTQMNNSDTEHPQMQLSQAWKKVVVQLSRVSAWFRCT EYQEGRHLEESAYIAKKANGYFSHHCLSFVQDRIDQLIADICTGIEEEEGPRIEIIMEEG VPIVASSEEPKEKETNPDPLKQLIRCFQRAATSEETAASAIHEDSLYIRFADVMAKSIHI EEEDGDDGEEGEIDQAAKEEQTQALRGEQAVLASRGAAIMCLMYLSASGGEPNEMVAQTL QLGIHLLSGGNVEIQKMLIEYLQLKKDVRFFTSMAGLMNKCSVLNLEMFERQIKAEGLGM GAELASGDNQNLNDADFTCSLFRFLQLTCEGHNLEFQNYLRTQPGHTTSVNLINCTVDYL LRLQESVMDFYWHYSSKEVIDEGGKEYFLRAIQVCSQVFNTLTESIQGPCVGNQMTLANS RLWDAINGFFFLFAHMMEKLYKNSTQLELLREFLNLQKDMIVLMLSMLEGNVLNGSIGKQ MVDALVESQPSVEKILKFSDMFLKLKDLTTSQAFQDFDTNQDGWISPKEFQRAMESQKMY TVEDITYLMMCTDVNNDGKVDYMEFTERFHNPARDIGFNLAVLLVNLKEHITNDPRLEKI IEKAQTLLEYFDPFLGRIEIMGSSKRVEKIYFEIQESWLEQWGKQQIRDSKNSFLFNVLQ DDGGDQGKLEAFINFCEDTIFEMQHAAAISSGDSDTKMERAIKQRDYFLQQTTASDQISE TFKSGYNYGISAASALSPQNITTTIKNVTTSVRQMTWTQLLYSIIILIIRAGLAIGWGGY LLLMTIFRFAYFLTTSSEEEETAKNDSLKEPPKMMNHEYVNIFKIHKYSFVFSHATFSPP IAQEFHHSHVGVDAFGVGMNADHLNVNSLPDFVPPPRPETPETVLSEEEKPLNSEPQSPT SPTAASKAPSIYESIGAPQMVQLQSEADFQQGQYEPKIAESNSTKTKGSILNMLARNFKT IEKITLYLAFFINVILLFHRVDISHTEAAETASEGDDDEDAVESIFITGLQFPYMEYEIT GWMLAQVLYWISVLHLSTSFALLVSFYQLKIPLITFKREKEIARKLMFDGCWITEEDSEE LGIVDTFMWYLDRIVISAKSFPMMYWDKFVRRKTRSKFKDQVDEETLTSILGEEKMSTDS SYDYRYSCWLWIGVIFTNGQFLYRVGYLLCSACGVFLSPFFYAFHLIDVVLSFPMLKAIL QSVTHNLQQLILTIMMTLVVVYLYTVLAFNFFRKFYVQEGEDGEEPDRKCHNMLTCFIYH FYAGVRAGGGIGDELESPYGDDLEYPRMFYDISFFFFVIVILLAIMQGLIIDAFGELRDQ QESATEKLESSCFICDIGKETFDRMPRGFEIHTTKEHNFANYLFFLQHLVNKDETEYTGQ ETYVREKYDNRDWDFFPVGECFVKQYEDQLLQS NT seq 19542 nt NT seq  +upstreamnt  +downstreamnt atgaaactaataatactcattttgctcctcatactttattcattatgcgatgaaattacg acttcaacttctgaagaggacactgacatgactgcaactccatccacaacaactcctctt ctatctactgctcagaacccaggacttccgaaaacttcgattctcccaattgcactcaaa agtcctgttcccacattctccttctcatcattatctacgaatgactggctatcgtctatg ccaaccgttcagacattacttccccctccgatagctcccaccactatggaagttccggat aaggagacattcggattcaattcactgactcccttatggaccattcctaccaaaactcca gtcatatctcctatcaatgattctcctataaaaccaatgcaagatgtgttcccaccattc ccaactatgccaactctcccgactcttgctccattcacatttccgactcttccaccaccg acaactatgaaacctttgaacattacaatcgacccggaagctattatggatgtgccagag ataatcgctcattggggatatccggtcgaaacgcacaaagtcgtcacagccgatggctac atcctcactttgcatcgcattccgcatggaaaaagtaagcatattgccgttacgaatagt tcatttccgaataccaaaaaacttcttgagatgagacctcgaaatccgcatccaaaatgc ctaaaccggtcgtctttttgcaacacggacttctttgtacgtcttcgatttggctactca atctgccgagacagatacattttcgccgatcagggttatgatgtttggctgggtaacatg agaggaaacacttattcgaagcagcatgttagaatgacatcatctgacaggagattctgg aaatttagctgggaagagatggcgagatatgatttacctgctatgatcaattatgttctt aaaaatactagacagtcaaatttgtattacgtcggtcattcacaaggagctctcacaatg ttcgcaaaaatgagtgaagacccagaaatgtcaacgaaggtcaggaagttcttcgcactg gctcctgtggcaagaatgtctcatgtgaaggggctattccatgatttggggcaaatttat gagcaatacaatttggtgtaccaagttttcggagatggagagttcttgacaaataatatc ttcaccaagctccttacggatattttctgcgaccaagctgtgaacaatcccctttgtgag aacttcatttttgctgtctctggcccaaacagtaaccaattcaataattcaagaattggg atttatcttgcacataatccagctggaacttcctccagaaatatgcttcattttgcacaa atggtaaagactaagaggatgtctcgttttgattttgggaaagatctgaactcaaaaatt tatggggctcctctacctccagagtatgacattcgaagaatcaatagttctatttattta ttctactctgatttcgactggttggcaaatccgaaggacgttgagggattcttgattcca atgttgccaactagatctttgaagaaagccaccaaacttcgagatttcaatcacaacgat tttctatggggaatgagagccaggaaggagatttacgagaagattataaacactataaaa ttggatcagaggagagtgaaacttcagaatagtatggataggtttttcgaaaaagaagtg aatgaagacgatgaagaaacggaatatcggcaatggccattttacactgtatttcggtca aagagcacaacaatccgagagatctcagagagaaatgaaactgaaccgcgattaggcgtt catcttttttctttttgctccaaaaaaaaaatagaaacctcaataaatctcaaacatccc cataattttccgttcgttctgtcatgctcctcttttttcttcttttttttggcttttccc ttgtggtaccaccttcatttcgtttcttttttgacagatgaggagcagggaggaggagaa caggatgatgtctcttttctccgaacgtcgtcttcagttcgaagcgagttttatgaaata ttgctctctttttctctcgaaattcgttgcaacaaaaaaatagtgtcagaaagatgctgt tttattgtaacacagagagaatttttttgtcccttaggcaaaaagtacgcggttaactcg aaaaaaagcgaggcctcttctttcgaatcctattcagttcctttccgtctcctctcttct tcccctttggcctcgttttgtgcattcatctcccgtccgccttccaactttttgtcctct actacgcacatacaacccataaacgtatttctggggacacccacggaggaattaacattg tcagatttccagacatctcattacccgcatcaacgtgtactattagtttttttaataaca ttgagctctattttcagtagttcgaacttttataggatttactcgaaatacgtcatcctc tacgataatacatcgctctactacatagatatcgctgaaattgtttccagcatgttcaaa gtacctttgttcaaattttcagctaattcccgaagaacctttcaaaaaagttcctttgtt agacccttattcccagttgatgatagtgatctctctttagaaaacaaacaaggctcctgc ttttgccgatttgatctcgcctctaggctctccttttctttccatttacacccgagaata tgttatgtcgcacatatggcattctgccgtcccggtcccgcctattgttttttcgtcgtc tttttccttctcgccgactattctttattttttgtgctgatggtgactcttcagttttca gacaaagagactcctctcttcacattagaagtctgctctaggcagcaaaaccatagaacc cgccaaaaaaccgcacacaaacgcaaaaacacaagatacacaactcagtatattcatgat cacaattatgtaacgaagggagacatcgtctgcctctcctgtgttgcctcacacaacaga gatggagttctcgggtcagaaagagtttgtttgtgcacagaaggtttcggtaaccggatg tgtacactggaaaacgtatcggacaaggacatcccaccagacattgccatgtgcatgctc tatatcgataacgcactatcaatgagagcattacaggaaatgatgtcagcagacagtgat cataaatctgcttctggtgctggaggtcacaagactcttttgtacggacacgcggtacaa ttgaaacatgtgcagagtgaaatgtatcttgcctgcctttcgtcctgctcttcaaacgat aaactagcatttgatgtaggagtacaagaaacgaatgaaggagaagcgtgttggtggacc attcatccagcctccaaacaaagatcagaaggagaaaaagtgcgcgtcggtgatgacgtc attttggtttcagtggccaccgaaagatatttacacatggcatatagcaaaggctacatg gtaattgcatctttccatcaaacactatggaatatccagtctgtcagttcaggaagcatg agaaccagaaatatgggatttctcttcggaaatgatgttctgaggttgttccacggtaac gatgaatgcttaacaatcccagaaaactggagcgagcatccacaacacaagtcatcttcc aaaaaatctgaaaattatttcagcatggtaatctacgaaggaggtgccgcggtgacacaa gccagatcactttggagagtagaattagttcgaatgaaatggcatggagcactggttgga tgggaacaagtattccgaatcaaacacatcacatccggaaggtatctaggagttttggac aacgcggtgcaactttaccacaaagaaaaagcagatttcgaactgacagcctttgttatg tgccaaaataaagatcctaagaagcagatgctcgatgagaaagaggaagaaggaatggga aacgccacgatacgatatggagagaccaacgccttcattcaacatgtgaaaactcaactg tggctttcttatcaaacatctgaagtgacgaaaaaaggattaggaaaagttgaagagaag aaagcagtagcactgaaagatggtcacatggacgactgctacacttttttcatggctcta gaagaagaatcaaaatccgccagagtcatcagaaagtgttcatcggttctcaacaaattc ttgaaaggaatcgatgcattacaactggaaggaaatcaatcaaccgattggacaagagta gatctcaacgaagtactgaaattgatggaagatctgattgaatactttgctcaaccgaat gaagaacaagactttgaagagaaacagaatcatcttcgagcactgcgaagtcgtcaagac cttttccaggaagaaggagttctcaacatgatccttgacactatcgataagttttctcaa atggaagctcttcctgattttgctggactgattggagaagaaactcacatcaaatgggaa cagatctctacctatttgtatcttttggtggctgcaatgatcaaaggaaaccattacaat tgtgctcagtttgcttcagcccaaagacttgattggctcttcggaagattgagtaatcca caatcagctgaaggaattctcgatgtactgtattgtgtgttgactgaatctccagaagca ttgaatatgatcaacgaagggcacattcgatctgtcatttcgctgttagaaaaagtggga agagatccaaaagttctggatgtgttatcgtctctctgtgaaggaaacggaatggctgtc agaagttcacaaaaccttatcactcaatatctgttacccggaaaagatcttttattacaa acatcaatgagagatcatgtatccagtatgatgcccaacgtgatgctcggagttgtcgat ggatccgctctattccgaaaatggtatttcgaagcagaagtggaacacatcgaaaccatg accaaacagactccatatcttcgaatcggatgggcaaacagtgttggattcaagccgttc cctggatctggagacaaatggggatgcaatggagttggagatgacttctattcttacggt tttgatggaaaatcaatgtttttcggaggaaaatcaagaatagttggacacaaacttttg gagaaaggtgacgtcatcggatgctccatcgacttgacgattcctgaaatcagattcagt gtcaacggatcctacatgagtggatctttcaaaaagttcaacaccgacggatatttcttc cctgttatgtccctctctgccaaagtctcttgtcgttttatcttgggagggaatcaagga agattgagatatggaccacctactggattttcggcagttgtggaagcagtcaacggagaa ttaggtatcactgattgcctatcattcggtgatttgggaaagaacattttctgtggtcca cagacaattttcaacaatttggaaccattcattccaactcccatcgacgtttcaaccacc caactcacacaccatgcaatggaaatgcatcagaaatatgctgaaaatcttcacgagcta tgggcaatgaggaagattgaacttggatggtcatatggagaaacaagatcagaaacatct agaaaacatccgtgtctcacgagattcgagctgctcccggaaactgaaaagaagtacaac ataatgttggcattgacaacaatgaaaacaattgaagcccttggataccacctcattact gacgatccaccatgcagactgagagccgtgcgattagcccaaaacttccaacaatcgaat ggctataaacccggaccactggatactcatgagatccaacttccagtcgaacttcagcca ctcacagaagcccttgctcgaaacactcacaacatttgggcgaaggaaaagatcaaaaga ggatggacgtttgggctgagtgaacacgtggatgccacacagaagagatcacctcatctg gtcccgtatgagcaggttgacgagagaatcaaacaggccaatcgagaatccgctgctgaa aatattagagctctccaactattcggtattttcttggaaccaccagcacacgaacatgat gaaattgccgagaaggagttgagagcacgaaaagataataccagaacttatcgtgccgaa gccacgtatgcagttaatggaggaaaatggtactttgaatttgaaattctgactgctggt tacatgaaaatcggatggatggatatcggatcaacaccagaaatccaactgggagctgat gatagaagttatgcttttgatggttaccttggcagaaaatggcatcaaggagcagaaaca tatggaaaggaatggaagatcggagatgtcgttggatgtttcctcgatctgaatgaccgt accatcagtttctctcttaatggagaacttcttcttgacccatctggatctgaaatggca tttgataatgttgtatgtggagatggactagttccagcaatgacacttggaagtggacag agaggaagacttaactttggacaacaatccaattctctaaaattcttcacaacttgcggt ctacaagaaggatacgaacccttctgtgtcaacatgtacagaactatgccaatgtggttt gccaagcaacttccaagattcgaagatatttccactctcaagtcaggatctatattagaa gttactagaattccagcaactggaaatagtccaccatgcctgaagatattgcaaaaagta acgatatcggaaggaggtccatccgagaaagcaaagatggagtacatcagattgtcatta ccggtcaagtgtaatgacacttttgtgaagaacaaagacaaagaagcgattcggcgtcag cttcaagactacaagcctcgttcccaatcagttgtcagtcagattcgtgctccaggaatt cccaaagaattcgacgataataaagagaagaagggattcttgagaagtatgcttggatcg aaagactctcatgaatcagatgacgatcggaatagatctagaacaacatcaaagcaacca agtatcgaaggagatgaaccaccagcagtcaggtatgtcatttcctattttcgtttgttg ttctcttttattttttcgactagaagtcgttacagtcaacgtcggcgtgttctaacccta atgaacttcggtatgtattcgttcgacgaatcgattctgacgtggttgcacgtcaacgaa gaggataatcacaaatggcaggacgtgttgagaagaagtcttctcgaacttccacatgaa gaacgacaaattgctgaagagcatatgagagatttgaatgatcgtcatgctgaaaaacca aagaaaggcggcattctgagcagactgcgtgattccagcaacacccgaaagaatttcaga gatagcgatagaaggaaagaggataaggcagcagctttaagacagatgaaatccaactca agaagttttgacgccggaagtcttgatacttcaactctcccaactggtcaaaaggatgta 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gtgtttcagaaacgagaagaagaaggtgcttggatcccacgtacagtcgacgtctcgaga tgtgagatcaatcgagatttggaaaagatgacagagctgttcgctgaacatttccatgac tcttgggcaagcagaaaactggagaaaggttgggttcatggcggtttgtactcaagagcc aacttcactcatccacgtctgaagccgtttgctttgctgaaagattttcttattctctca tttcaggaaaaatcgttctacaaagagagatgttcagagtgcctaaaagcattgatggca tggagttattcattcgatatggtggatagagatgcaaatgatcgtgcttcagctgctcga actctttctggaacttcaatttcgaactttgccccgaagccaatcgatttaagttctatg acccttgaaaaggatatggtcaatgcagctgagaaaatggctgaacactctcatttgatt tgggctaagaaagtgatgaatgatctgaacacgaagggaggattcatgccaattccactg gttccatgggatttgttgactgatttcgaaagacgaaaagatagattcagagcatccgag attctgaagttcttgcaataccatggctatcatgttaactgtccaaaagacgagcagtct caaaacgaccgaatgaagagtgaaggggaaagatcatcagtagagaagagattcgcttac aatctgttagagaaactgatcacttatctggaacaagcaagtttgaaaatgaagtcagtg aagccatctcaagaattgacaagacgaaattctttcaaaaaagagggacaagatgtgaaa ttcttcgagaaagtcgttctgccattgatgcatgcttacttcaatgctcacaaaaattat ttcctggagggatcgtcgatcgtgcagactggaacagccagtaacaaggaaaaggaaatg gttgccaatctgttctgtcgtctcgcagctcttctccgtatcaagaatcgagcattcgga agtgtcgctaagatcactgtcaaatgccttcaaggattgacacaggcacttgatctcaga acattggtcaaagtcaattctgatatcgttcgcacatctcttctcacattcttcaacaac tgtgctgatgatttgtatgctgctgtaaacgaactcaaggacggaggccaatattcactg atcagaggacaagctttgaaatcgtggaactcttttgagttcgcaaaccagatgatcgtt cctgttcttactacaatgtttgcacaccttgccagaaatcattttggaactgatttgctt ttggatgacatccaagcagcctgttataaaattctggactctctgtacatggtcactgga ctgaacagctccatctctcacagaaagtttattagcagtgaaagcgagaaacatcgtcct ggtcttggtcaatgccttgctgcctttgcctcttgcttcccggttgcctttttggaaccg gaatttaataagagcaacaagttctcagttctcgccaagacccaagatcaatccgttcaa gttcaagaaatgcttcagaatctttctactcatattccacatctcgagaaactattgaca gatcttgaaacagttgccaacaacaacactatgtattctgatgtgcccaacgtttacgat gtggatcttccattgatgtgctcgtatatggcacattggttcaatgttggaccagatgga aagagagataaggatgatcagagagcaagtgtgattcagacaactagtgtcagttgtgat catatcaacagaattttcaatgcacttctcaagatgatacgaaaccatgttggaattgaa aatgctccgtggctttgccgagtgaactgtaatttcatcatcttcgctgtacaaatcatc caaaatgtcacatccgatccagttcgagaattcgttttaccaatcgcagaaagattgaga agaatgagtgagaaggcgtacaaagaagaagagcacatgagaacccatccagatgatgct gatgaaggaactgttgcagaggtaattacaaccgaaagatcgaattctactagctttaat tccaggacaacgctcgcctcgtcctacacggaccttcatcgtgcccagtggctcaaatct cccacctgggaaacagatggagtctatgaaaacgtggcggtcatcttcagaatctggagt cagagtcaacatttcaaacgagaagaactcaactacgtggctcaatttgaagaagacgcc gctgctatgggcggtggagatatgaagactggaaaagcagcgattgcagagagaaagaaa aagagaagagagggacaggttagttcgaggggatcacagaaaattcgaatttcaaaaaaa aaaagaagcaaaaccataataatacaggataagatgaaagagtatttcgacagaaacgga agaccaatcgtaagttttgacacgaccgaaaaaccttttgttgagcaaatatgttgtgtc tcgtcgtccgattatttcgatcattcaattaagaaagacaaacatgctgcaagtattgtg atcgcttgcctcaaaagacttcttcccgttggattgaacgttttcggtggaagagaattg gacattgtccaacagtcaaaggaaaaattcattcagaaggaaaccgaagagaagatccga gaattcatcaaaggacttcttgagattccagtcaaaactgatccaactgataagaatgca tggcaactttcactttaccgcaaaattggaaagtcccaaatgcgcggaaaagacgagatg tctcaagaagcggtgattgagaaaattttcaacatgggacaagtcagcgctattctccac 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caatggggcaaacaacagattagggattcgaagaattcattcttgttcaatgttctacaa gatgatggtggagatcaaggaaagctggaagcattcattaacttctgtgaggataccatc tttgaaatgcaacacgcagccgccatctcatctggagacagtgacacgaaaatggaaaga gccatcaagcagagggattactttttgcaacaaacaactgcatcagaccaaatctctgaa actttcaagagcggatacaactatggtatctctgctgcgtctgctctcagcccacagaat atcacaacaaccatcaagaatgtgaccacttccgttagacaaatgacctggacccagtta ttgtattccattatcattcttatcattagagctggattggccatcggatggggtggatat ctccttctgatgacaatcttccgattcgcttatttcctgacgacgtcatctgaagaggaa gagacagcgaagaatgatagtctaaaagaaccaccaaagatgatgaatcatgagtatgtg aacatctttaaaattcataagtattcctttgttttcagtcatgcaacatttagtccaccc atcgcgcaagaattccatcattcgcatgttggtgtggatgcattcggagttggaatgaat gcagatcatcttaacgtcaactccctaccagatttcgtgcctccaccaagaccagaaaca ccagaaactgttctgtcggaagaagagaagccactcaattcagagcctcaatcaccaact tccccgacagccgctagcaaggcaccaagtatttatgaatcgatcggagcaccacaaatg gttcaactacaatccgaagcggacttccagcaagggcaatacgaaccaaagatcgctgaa tcgaattccacaaagaccaaaggatcgattcttaatatgctcgccagaaacttcaaaacc atcgaaaaaattactctctacttggctttcttcatcaacgttattcttcttttccatcgt gtagacatcagtcatacggaagctgcggagacagcttcagaaggcgatgacgatgaagat gccgttgaatcaatcttcatcacaggacttcaattcccttatatggaatatgagataacg ggatggatgttggcacaggttctgtattggatcagtgtactccatctatcaacatcattc gcccttttggtctcattctatcaattgaaaattccacttatcactttcaaacgtgaaaag gagattgccagaaaattgatgtttgacggatgttggatcacagaagaggattcagaagaa cttggaatcgttgatacatttatgtggtatttggacagaatcgtcatctctgccaaatca ttccccatgatgtactgggacaagttcgtacgcagaaagacacgatcaaagttcaaggat caagttgacgaggagactttgacttcgattttaggagaagaaaagatgtccactgattca agctacgactacagatattcttgttggttgtggattggagtcattttcaccaacggacaa ttcttataccgagtcggatatctactctgttccgcttgcggagtcttcctttcaccattc ttctacgcattccacctcattgacgtcgtgctctctttccccatgttaaaggctatcctt caatctgtgacccataatttacaacaacttatcctcaccatcatgatgacacttgtagtc gtatatctctacactgtccttgcattcaacttcttccgtaaattctacgttcaagaggga gaagatggcgaagagccggatcgaaaatgtcataatatgctcacctgtttcatctaccat ttctacgccggagtgcgtgccggaggaggtattggagatgaactggagagtccatacgga gacgacctggagtatccgagaatgttctacgatatttcattcttcttcttcgtcatcgtt attcttcttgccatcatgcagggtttgatcatcgacgctttcggagagcttcgtgatcaa caagaatccgctaccgagaagctcgaatcgtcttgtttcatctgcgatatcggaaaagaa acgttcgatcgaatgcctcgaggttttgaaatacatacaaccaaggagcacaactttgct aattatttgttcttcctacaacatctggtgaacaaagacgaaacagaatataccggtcaa gagacctacgtacgtgaaaagtacgataaccgggattgggatttcttcccagttggagaa tgtttcgtcaaacaatacgaagatcagctactacaatcataa

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