Corvus brachyrhynchos (American crow): 103620991 Help Entry 103620991         CDS       T08418                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism cbrc  Corvus brachyrhynchos (American crow) Pathway cbrc04020   Calcium signaling pathway cbrc04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cbrc00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     103620991 (RYR3)    04020 Calcium signaling pathway     103620991 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cbrc04040]     103620991 (RYR3) Ion channels [BR:cbrc04040]  Voltage-gated cation channels   Ryanodine receptor    103620991 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 TBK1_ULD Motif Other DBs NCBI-GeneID:  103620991 NCBI-ProteinID:  XP_017597420 LinkDB All DBs Position Unknown AA seq 4900 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLASTGDNASEGFIRKAAQGGGHRTLLYGHAILLRHSFS EMYLTCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSV SSERYLFFSVSNGNIQVDASFMQTLWNVHPICSGSNITEGYLLGGHVVRFFHGHDECLTI PSTDQNDSQHKKVFYETGGAGIRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGKYLA LNEDEGVVILDREKSDTTSTAFCFRASKELKEKQESSLKRDIDGMGIPEIKYGDSICFVQ HVATALWLTYKAQDAKSARLGPLKREVILHQEGHMDDGLTLQRCQREESQAARIIRNTTS LFSHFISGKMMNAASLVFHSGNNRALSPTALPVEEMAQTLQDLITYFQLPEEYLQHEDKQ NKLRSLKNRQNLFKEEGMLALVLNCIDRLNDYNSAAHFAGITREEHGTSWKEILNLLYKL LAALIRGNRNNCAQFSSNLDWLISKLDRLESSSGILEVLHCILIESPEALNLISEEHIKS IISLLDKHGRNYKVLDVLCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIR PNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGN GVGDDLYSFGFDGLHLWSGRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQ GMFENFSTEGFFFPVVSLSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEP VKEYKRDFEGVRDLLGTTQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMN KIELGWTYGKIRDDNKRHHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPA AEEDLKKVKLPKNYMMSNGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGW TYGIQQDLKNKRNPRLVPYALLDERTKKSNRDSLREAIRTFAGYGYSIEPSDQEIADQTV EKVSIDKIRFFRVEQSYAVKSGKWYFEFEAVTGGDMRVGWARPGCRPDVELGADDQAFVF EGSKGQCWHQGSGFFGRSWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGI ENGFVPVCALGLSQIGRMNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPT FVNVPKNHPHIKIWRIDGTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPVEFHSSFNFG MGVENASSDVFQKRKHSQEVAPLSTTYFYSLRIFAGQDPSCVWVGWVTPDYHFYSENFDL NKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDIIANSQRSGRSNVDIEIGCFVDLATGM VSFTANGRELGTCYQVEPNTKLFPATFLQPTSTNLIQFELGKLKNTMPLSAAIFKSEERN PVPQCPPRLDVQTITPVLWSRMPNSFLRVETERVSERHGWVVQCLEPLQMMALHIPEENR CVDILELCEQEDLMMFHYHTLKLYSSVSALGNTRVAYALCSHVDVSQLFYTIDNQYLPGL LRSGFYDLLISIHLEHAKQAKLMMSNEFIIPVTDETRNIKLYPNETKKHGLPGVGLSTCL KPAFNFSTPCFIATSEDHQTSTPEIPLEILKSKAISMLTEAVQCSGSHIRDPVGGQVAFQ FVPVLKLIATLLIMGVFDDDDVKQVLLLIDPTVFGDHKEETEERTEKEEVTQVEEKAVEA GEKAIKQAKVPAKGLLQTRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQY NQKYRYNELMQALNMSAALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIREELYEF HDDLLIHCGIPLEEEEEEEEDSSLTGKLRSLMYKIKGPPKAEKLEPKEEEEKAPTTLKEL ISQTMVRWSQEDQIQDPELVRIMYSLLRRQYDSIGELLQALRKAYTISATSVKDTINLLA ALGQIRSLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGG DQSQQIVFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLD VAAASVMDNNELALALEEPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSF LRFAVFANSESVEENASVVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPSRDL PSQAYKREGDEEEEEEETVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSIL RSLVPTEDLVGIISIPLKLSTVNKDGTVNEPDMSASFCPDHKAPMVLFLDRVYGIKDQSF LLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHAS LVDSMLHTIYRLSKGRSLTKAQRDAIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYC KMPLKLLTNHYEQCWKYYCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKY DPELFRMALPCLSAIAGALPPDYLDTRIMSTLEKQTSVDPEGNFDPKPVSTSNLVLPEKL EYIVSKYAEHSHDKWAFEKTNSGWKYGVSLDENMKTHPLIRPFKTLAEKEKEIYRWPARE SLKTMLALGWSLERTKEGGEAVIHQRENEKLRSISQSSQGNGYSPTPLDLSNVALSRELQ GMVEVMAENYHNIWAKKKKMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQV NGIIISRGMNDTELDASSMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHD QEIKFFAKVLLPLVDQYFTNHCLYFLSSPSKTLSSSGYASNKEKEMVASLFCKLAALVRH RISLFGSDSATMVNCLHILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKL GKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHISQYHFGIDLLLGDVQVSCYRILCSL YSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGM PDTVEEMCPEIPQLDRLIKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWEKGSESV PQSAGPCCTMITSEHLSLVLGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRS HFIPTLDKLKKKAMKIVMEEEQLKADSKNDTQEAELLILDEFAVLCRDLYAFYPMLIRYV DNNRANWLKKPDADSDELFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKS KMSKQNARRGMAMQVKSGGQDQERKKSKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGD QELISLAKTRYSHRDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDILKSDGPTDPEK NVERVQRISAALYHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHKISN FFLSTFQRVWLEKVHEKTQYDRLILKLTTSPKKDEEEEEETEKNHPDPLHQIILYFSRSA LIERSKLEHDPLYIAYSAMMAKSCQEEEEGDEEKEKTFEEKEMEKQRTLYQQARLHDRGA AEMVLQMISASKGHTGPMVVETLKLGIAILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGL MQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQHDEFTRDLFRFLQLLCEGH NNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDESGQRNFSKAL AVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSAQIELLKE LLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTNSD AFKEYDPDGKGIISKKEFQKSMEAQKQYIQSEIELLLSCTEADENDMFNYVDFVERFHEP AKDIGFNVVVLLTNLSEHMPNDPRLQSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYF EISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETD SSERPEEEEEAEPAYVMDIGDDEEEEKSLEPASAFAVACVAVKKNVANFFKMVTVKNLRK QYRKVKKMTIKEMVKVFFSFFWILFVGTFQLFFSIVWGIFQILWSTVFGGGLVEGAKNIK VTKILGDMPDPTQFGIHDDVMEAEKAEGAEHGIRAELGEFVKSEKGETDIIADIFGIPTK KEGSKHGHDAGLGDIAEILGTEIQTPLENTVHKKKRLQISEIAKEAGTQRKTEAEKADME DGEKQDKAKEVQSEQLEEGKMKKKKRRHGQKIEKPEAVMANFFKALEIYQTKILHCLARN FYNLRFLALFVAFAINFILLFYKVTEEPLDEVEEDSNLWNSFAEEEEEEGMVFFVLEEST GYMAPALRALAVIHTIISFVCVIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPTEDD IKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFSPVEES EPEEASLVSWLSSIDTKYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIA MGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCD DMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLII DAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLIN KDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14703 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgatgaa gtagtacttcagtgtgttgccagtattcataaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggagccaacatcagaagctaaatatgtcccc ccagacctttgcatctgtaatttcgtccttgagcagtcactgtctgtcagagcccttcaa gaaatgctggccagcacaggggataatgctagtgaagggtttataagaaaggcagcccaa gggggtggccacagaaccctgctgtatggccatgctatactacttcgacattcgttcagt gaaatgtatttgacatgtttaacatcatcgagatcccagacagataaacttgcctttgat gtgggactacgagaaaatgcagcaggtgaggcatgctggtggacaatacaccctgcttct aagcaaaggtcagaaggagaaaaagttcgaataggtgatgaccttatcctggtcagtgtg tcctctgaaagatacctgtttttctccgtgtcaaatggaaatattcaggtggatgcctcc tttatgcagacattatggaatgtacatcctatatgctcaggaagcaatattacagaagga tatcttcttggtgggcatgtagtacgttttttccatggccatgatgagtgcttgacaatt ccatctacagatcagaatgattcacagcacaagaaagtgttttatgaaactggaggagct ggcattcgagcaaggtcgctgtggagagtagaacctctccgaataagctggagtggaagt aacatcagatgggggcagcctttccgtcttcgacatattacgacaggaaagtacttggct ctgaatgaagatgaaggagtagtaatattagacagagaaaagtcggacacaacatctact gccttttgttttagagcatcaaaggagctgaaagaaaagcaggaatctagtctcaaacgt gacattgatggaatgggaatcccagaaataaagtacggagattcaatctgttttgtccaa catgtggccactgccttatggttgacttacaaagcacaggatgctaaatcagcacgttta ggtcccttgaaaagggaggttatattacaccaagaaggtcatatggatgatggtctcaca ttacaaagatgccagcgtgaggaatcccaggctgctcgaatcattcgcaatactacaagt ttattcagccactttataagtgggaaaatgatgaatgctgccagtcttgttttccatagt ggaaacaacagagcactatcacccactgccctgcctgttgaggagatggctcagactctg caagacctgatcacttacttccagcttcccgaagaatacctgcaacatgaagataagcaa aacaaacttcgctcactcaaaaacagacaaaatctattcaaagaagagggaatgctggca ctagttctaaattgcattgatcgcttaaacgactacaacagcgcagctcattttgcagga attacaagagaagaacatggtacatcatggaaagaaattttgaatcttctttataaattg ttagctgctctcattcgtggcaacagaaacaactgtgctcaattttccagtaaccttgat tggctgatcagtaaattggacagattagaatcttcctcaggtattttggaagtgttgcac tgcatcttgattgaaagcccagaagctttaaatctaatatctgaggaacacataaaatcc attatttcactgttggataaacatgggcgcaattacaaggttctcgatgtactttgctct ctgtgtgtctgtaatggagttgcagtccgtgccaatcaaaatttgatctgtgacaattta ctgcctagaagagacttacttttgcaaacacgtttgattaatgatgtgacaagcataaga ccaaacatatttttgggtgttgctgagggctctgcacagtacaagaagtggtactttgag ttaataattgatcaggttgatccattcttgacggcagaacccacccacttacgagttgga tgggcctctacttcaggttatgccccctatcctggaggtggagaaggatggggaggcaat ggtgttggtgatgacctctactcttttgggtttgatggccttcatctgtggtctggtcgg gtacccagagcggtagcatctgtcaatcagcatttattagcatctgatgatgtggttagc tgctgcttggatttaggtgtccccagcatttcattccgcattaatggacagcctgtacag ggaatgtttgagaacttcagtacagaagggtttttcttccctgttgtaagcttatcagca ggcgtaaaagttcgtttcttgttgggtggacgtcatggagagtttaaatttctgcctcct gctggctatgctccctgttatgaagcattgcttccaaaagagaagatgaaactggaacca gtcaaagaatataaaagagattttgaaggtgtgagggatttgttgggtacaacacaattt ctctcacaagcttcttttatcccttgtccaatagacaccagtcagattgcccttcctttt catcttgaaaagatcagggacaaactagctgaaaatatccatgaactgtggggaatgaat aaaatagaactgggctggacatatggcaagatacgggatgacaataaaaggcatcatcct tgtctcgtggaattctcaaaattgcctgagacagagaagaattataatctacaaatgtca actgaaaccctcaaaacccttttggcccttggatgtcacattgttcatgctcatccagca gctgaggaagatcttaaaaaagtcaaacttcctaaaaattatatgatgtcaaatggatat aaacctgcccctcttgatctttctgaagtgaaattgttaccttctcaagaatttctagtt gacaaactagcagaaaatgcacataatgtctgggcaaaagacagaataaagcaaggatgg acctatggcattcagcaggatcttaagaacaaacgtaatcctcggctagtgccatatgca ttattagatgaacgtactaaaaaatcaaacagagatagcctccgtgaagctattagaaca tttgcaggctatggttatagtattgagccatctgaccaagagatagctgaccagacagtg gaaaaagtcagcatcgacaagatacgatttttcagagtagaacaatcctatgcagtgaag tctggaaagtggtactttgagtttgaagctgtgacaggtggagatatgcgtgttggctgg gccagaccaggctgtcgacctgatgtagagctgggagctgatgaccaagcatttgtattt gaaggaagcaaaggccagtgttggcatcaaggcagtggattctttggacgaagctggcaa ccaggagacgtggttggttgtatgataaacctggacgacaagtcaatcatctttactctg aatggagagttgcttataaccagtaaaggttcagaacttgcatttgctgactttggaata gaaaatggttttgttccagtttgtgcactgggcctatctcagattggtcgcatgaacctt ggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaaggttttgaa ccttttgctgttaacatgaaccgagatgttgctatgtggtttagtaaacggttaccaaca tttgtcaatgtgccaaaaaatcatcctcacattaagatatggagaattgatggaaccatt gagagtccacctcggttaaaagttactcacaaaacatttggcacacagaacagcaattca gacatgatatattgtcgtttgagtatgcccgttgagttccactcatcattcaacttcggc atgggtgtggaaaatgcctcatctgatgttttccaaaaacgaaagcatagccaagaagtt gctcctctttctactacgtatttttactcactacggatatttgctggccaagacccatcc tgtgtttgggttggctgggtaacacccgactatcatttttacagtgagaattttgaccta aataaaaattgtacagtgacagttactctaggtgatgagagaggcagagttcatgaaagt gtgaagcgcagcaactgctacatggtttggggaggagacataattgctaattcccagaga tcaggtcgcagtaatgttgatatagaaattggatgctttgttgacctggctactggaatg gtgtcattcacagccaatggaagagagcttggcacttgttatcaggttgaaccaaacacg aagctttttccagcaacttttttacagcccacaagcactaacttgattcagtttgaactt ggtaaattaaagaataccatgcctttatcagcagcaatttttaaaagtgaagaaagaaat cctgttcctcaatgtccccctcgccttgatgtgcaaacaattacacctgttttatggagc cggatgccaaacagctttctaagagtagaaactgagcgtgtcagtgaacgtcatggctgg gttgtgcagtgtttggaacctctgcagatgatggcacttcatatcccagaagaaaacaga tgtgttgatatcttggaactatgtgagcaagaagatttgatgatgtttcactaccacact ttaaaactctatagctcagttagtgctctaggtaacactagagttgcttatgcactttgt agccacgtggatgtatctcagctattttatacaatagataatcaatacttacctgggctt ctacgttctggattctacgacttgctcattagtattcacttggagcacgccaagcaagcc aagctcatgatgagcaatgaatttatcattccagttacagatgaaactcgaaatattaaa ttataccccaatgaaacaaagaagcatggtttacctggagtagggcttagcacttgtctt aagccagcctttaatttttctactccatgctttattgcaaccagtgaagatcatcagaca tccaccccagagatacccctggagatacttaaatccaaggccataagtatgttaacggag gcagtacagtgtagtggtagtcatatacgagaccctgttggaggacaggttgcattccag tttgttcctgttcttaaactgatagcaacattgctcataatgggtgtttttgatgatgac gatgtgaagcaggtgttactcctcatcgatcccactgtgtttggagatcacaaggaagaa acagaagagaggacagagaaggaagaagtgacacaagttgaagaaaaagctgtagaagct ggggagaaagcaatcaaacaagcaaaagttcctgcaaagggcttgttgcagacaagatta ccagaatctgttaagcttcagatgtgtcatttactcaattatttttgtgactgtgaacta caacatagagtggaagcaattgtatcatttgcagaccgttacgtatcaaaattgcagtat aaccagaaatacaggtacaatgaactcatgcaagccttaaacatgtctgctgcattgact gccaagaagactaaagaatttcggtctcctccacaagaacagattaatatgttgctgaat tttcaactgggagaggattgtccctgtccagaggagattcgggaggaattatatgaattt catgatgatcttctaattcactgtggtattccactagaagaagaggaagaggaagaggaa gattcctccttgactggcaaactccgttcattaatgtacaaaatcaaaggtccaccaaaa gcagaaaaattggaacctaaggaagaagaagagaaagctcctactacactgaaagagctc atatcacagacaatggtgcgctggtcccaggaagatcagatccaagatcctgaattagtt cggattatgtacagcctccttcgtaggcaatatgacagcattggtgagctactgcaagcc ctgaggaaagcatacactattagtgctacctctgtgaaggataccattaatctgcttgca gcactgggccagattcgctcacttctcagtgtgaggatgggaaaagaggaggaattgcta atgattaatggattaggggatataatgaacaataaggtgttttatcagcatcctaactta atgagagtcttaggcatgcatgagactgttatggatgtgatggtaaatgtgcttggagga gatcaatctcagcagatcgtttttcctaagatggtggcaagctgttgtcgattcctgtgc tacttctgtcgcattagtcgtcagaaccaaaaggccatgtttgagcatctcagctactta ctggaaaacagcagtgttggactggcgtttccttcaatgagaggttcgacaccactcgat gtggccgcagcctctgtaatggacaacaatgagcttgcactcgcattggaggagccagat cttgataaggttgttacctacctggcaggttgtggcctgcagagttgtccagtactgctg gctaaaggatatccagacattggatggaacccaatagagggggagcgttacctgtcattc ttacgatttgcagtttttgctaacagtgaaagtgttgaggaaaatgcaagtgttgttgtc aagctccttattcgacggccagagtgctttgggccagaccttaggggagaaggaggaaat ggtttgctggctgctatgcaggaagctatcaggatctcagagaatcctagtcgtgacctt ccttcccaggcatataaaagggaaggtgatgaggaggaggaggaagaggagactgtgcac atgggaaatgcaatcatgtcattttactcagctctcatagatttacttggacgctgtgca ccagaaatgcatcttattcaaagtggaaaaggggaagctattcgaatcaggtcaattctt cgatccctagtgccaactgaagatttggtgggtattataagtataccactaaagttgtca acagttaacaaagatggcactgtaaatgagcccgacatgtctgccagtttctgtcctgat cacaaagcacccatggtactcttcttggaccgtgtctatggtattaaggaccaaagcttc ctccttcacctattggaagttggatttctaccagatttaagagcctctgcctctctggat acagtttctctaagtaccacagaggccgctctcgcactaaatagatatatttgctcagct gtgtttccattactcaaaagatgtgctcccctcttttctggaacagagcatcatgcctct ctggttgactccatgcttcacacaatatataggttatccaagggacggtcccttacgaaa gcccaaagagatgctattgaggaatgcctgcttgctatttgccaccatttgcgtccctct atgctacaacagctgctgagaaggctagtttttgatgtgcccttgctcaatgaatactgt aaaatgcctctcaagcttctgacaaatcactatgagcagtgctggaaatactactgtctg ccttcaggaatgggaagctatggaattgcagcagaagaggagttacatttaactgaaaaa cttttctggggaatatttgattccttgtctcataagttcctatctctcctgcagaagtat gatccagagctctttcgaatggctttgccttgtctaagtgctatagctggagccttgccc cctgattatttagacacacgaattatgtcaaccttggaaaagcagacttcagtggatcca gaaggaaattttgatcccaaacctgtcagcacatcaaaccttgtacttcctgagaaactg gagtatattgtaagcaagtacgctgagcattcccacgataaatgggcctttgaaaagact aatagtggatggaaatatggtgtttcactggatgaaaatatgaagactcacccattaata aggcccttcaaaactttagctgaaaaggaaaaggaaatttatcgttggcctgccagagaa tcattgaaaaccatgttggccttgggatggagcctagaaaggaccaaggagggaggagaa gcagtaatacatcagcgtgaaaatgaaaagctccgtagcatatctcagtctagtcaggga aacgggtatagcccaacaccacttgatctctcaaatgtggcactttctagggagcttcag ggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaagaagaaaatg gagttggaaagcaaaggtggaggtagtcatcctttattggtgccttatgacacattgaca gccaaggagaaatcacgggaccgtgaaaaggcacaagagctgtttaagttccttcaagtc aatggtataatcatatctcggggcatgaatgacacagagttggatgcttcatccatggaa aagaggtttgcctttaagtttctgaagaaaattttaaaatatgttgattctgctcaagag tttattgcgcatttggaagctattgtaaccagtggaaaaactgaaaaatctccacatgac caagaaataaaattctttgctaaagttcttttaccattagttgatcagtactttacaaat cactgcctctacttcctgtcttctccatcaaaaaccctcagtagcagtggatatgcatca aataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctcttgttagacat aggatctcactttttggcagtgattctgctacaatggtgaactgcctgcacatcttagct cagtctcttgacacacgaactgttatgaaatcaggatctgagcttgttaaagcgggattg cgtgccttttttgaaaatgcagctgaagacttggaaaaaacttcagaaaatcttaaactg ggaaaatttactcattcacgaacacaaatcaagggtgtttcacagaatataaattatact acagtagcattgttaccaatcttaacatcaatttttgaacatatttcacaatatcacttt ggaatagatttacttttgggtgatgtacaagtttcatgttacagaattctttgtagcctc tattctcttggaactggaaagaacatctatgttgaaaggcagcgtcctgcgcttggtgag tgtttagcatctcttgcggcagccattccagtggcattccttgaaccttctctcaaccat tacaatccgctgtcagttttcaacacaaaaagtgcaagagaaagagcaattttaggcatg cctgatacagtagaagaaatgtgtccagagatccctcagctggatagactgataaaggaa ataaatgatttagcagagtctggagcaaggtatactgaaatgcctcatgtaattgaggtg atcttacccatgctatgcaactatttatcctactggtgggaaaaagggtccgagagtgtt cctcaaagtgctgggccttgctgtacaatgataacatctgagcatctgagcctcgttctt ggaaacattctgaaaatcattaacaacaatttgggaatagatgaagcatcttggatgaaa agaattgcagtttatgctcaacccatcatcagcaaagccagacctgatctcctcagatct cactttattccaacactggataaattgaagaaaaaagctatgaagatagtaatggaagag gaacaactgaaagcagacagtaaaaatgacacccaagaagctgagctactcattcttgat gagtttgctgtactttgtagagacctttatgccttctatccaatgttgatacgttatgta gacaacaacagagctaattggctaaagaaaccagatgcggattctgatgaactctttcga atggtagctgaagtttttatcctgtggtgtaaatcacataattttaaaagagaagaacaa aattttgtgattcagaatgaaatcaacaatttggcatttttaacaggagacaccaagagc aagatgtctaaacagaatgctcggaggggaatggccatgcaagtaaagtctggaggacaa gatcaagagaggaagaaatcaaaacgtagaggggatttgtactccatacaaacatccttg attgtggctgcacttaaaaagatgcttcctattggtttgaatatgtgtactcctggagac caagaactcatctctttggctaagactagatacagccatagggacacagatgaggaagtc aaagaacacttacgcaacaacttacacttgcaggaaaagtctgatgatccagctgtgaaa tggcagctaaatctgtacaaagacattttaaagagtgatggacctactgaccctgagaaa aatgtggaacgtgtgcagaggatatcagctgctctgtatcatctggagcaggttgaacaa ccactgagatcaaaaaaagctgtttggcacaaactcttgtcaaaacaacgcaaaagggca gttgttgcatgtttcagaatggcaccgttatataacctgccaagacacaaaattagcaat ttcttcctgagcacctttcaacgtgtttggctggaaaaagtacatgaaaaaactcagtat gacaggcttatactcaagttaacgacatctccaaaaaaagatgaagaggaagaagaagag actgagaaaaaccatcctgatccacttcatcagattatcctctattttagtcgcagtgct cttatagaaagaagcaaactagaacatgatcctctatatattgcctattctgctatgatg gcaaaaagctgtcaggaagaagaagagggagacgaagaaaaagaaaagacatttgaggag aaagaaatggaaaaacagagaactctctatcagcaagctcgcttacatgatcgtggagct gctgagatggtccttcagatgattagtgcaagtaaaggtcatacaggacccatggttgtt gaaacactaaaacttggtattgctattctaaatggtggaaataccatagttcaacagaaa atgctagactacctgaaggagaaaaaggatgctggattttttcagagcctctctggcttg atgcagtcctgcagtgttcttgacctgaatgcgtttgagagacagaataaagcggaaggc ctgggaatggttactgaagaaggaactctcatcgttcgtgagcgtggtgaaaaagtcttg cagcatgatgaatttactcgagatctatttagatttttgcaactgctctgtgaagggcat aacaatgactttcaaaattacttacgtactcagatgggaaacaccacaacagtgaatatt atcattagtactgtggactatctcttgcgtcttcaggaatccatcagtgacttctattgg tactattcaggaaaggatgtcattgatgaatcaggacaacgtaacttttctaaagctttg gctgtcaccaaacaaatattcaattcccttacagaatatatccagggcccttgcataggt aatcaacagagtctggctcatagcaggctgtgggatgcagttgttggctttctccatgtg ttcgccaatatgcaaatgaaactttcacaggactctgctcagattgaattgcttaaggag ctgctagatctactaaaggatatggtagtgatgctcttgtcactgcttgaaggtaacgtt gtaaatggaactattggaaaacaaatggtggacacgcttgtagaatcatctagcaatgta gaaatgattttgaagttctttgacatgttcctgaagttaaaagatctgactaattcagat gctttcaaagagtatgatccagatggtaaaggaatcatttccaagaaagaatttcagaaa tcaatggaggctcaaaaacaatacatacagtcagagattgaattactgctgtcctgtaca gaagctgatgaaaacgatatgttcaattatgttgactttgtggaaagattccatgaacca gccaaggacattggatttaatgtagtagtattgttaacaaacctttcagagcacatgcct aacgatccacgccttcagagcttacttgagcctgcagaaagtgttcttaattactttgaa ccctaccttggccgtattgaaataatgggtggggccaagaaaatagaaagagtttacttt gaaatcagtgaatccagtagaacgcagtgggagaagccacaggtgaaggaatctaaaaga cagttcatatttgatgttgtaaacgaaggtggagagcaagaaaaaatggagctctttgtg aatttctgtgaagacacaatttttgaaatgcagttagcatcccagatttctgaaacagat tcatctgagaggcctgaggaggaggaagaggcagagcctgcttatgtaatggatattggg gatgatgaggaagaagaaaagtccctggaacctgcttcagcttttgcagtggcctgtgtt gcagtgaagaagaatgttgccaacttttttaaaatggtcactgtgaagaaccttaggaaa caatacaggaaagttaaaaagatgaccataaaagagatggtgaaagtatttttctccttt ttctggatcctatttgtagggacattccagttgttcttttccatagtgtgggggatattc cagattctttggagcactgtatttgggggtggcctggttgaaggagccaaaaacataaaa gttactaaaatattaggggatatgcctgatccaacacagtttggaatccatgatgatgtt atggaagcagaaaaagctgaaggtgctgagcatggcataagagctgaacttggggagttt gtgaagagtgaaaagggagaaactgacataattgcagacatttttggcattcctacaaag aaagaaggatcaaaacatggtcatgatgctggacttggagatattgcagaaatccttggt actgagatccagacacctttggaaaacacagttcataagaaaaaaagactacagatatct gaaattgcaaaagaagctggaacacaaagaaaaacagaagctgagaaggctgacatggaa gatggtgagaaacaagataaagcaaaggaagtacaatctgagcagctagaagagggaaaa atgaagaaaaaaaagaggaggcatggacaaaaaattgagaaaccagaggctgttatggct aacttcttcaaggctttggaaatttatcaaacaaagatacttcactgcttggcaagaaat ttttataacttaaggtttcttgctctatttgttgcatttgccatcaattttattcttcta ttttacaaggtgacagaagagccccttgatgaagtagaggaagactctaatctctggaac tcctttgctgaagaggaagaggaggagggcatggtgttttttgttttagaagaaagtacc ggctacatggcacctgctctaagagcactggcagttattcatactatcatctcctttgtc tgtgtgattggatactactgcttaaaggtccctctggttgtatttaagagggaaaaggag gtagctagaaagctggaatttgatggactatacataactgaacagccaactgaagatgat attaaaggacaatgggatcgcctcgttataaatactccgtccttccctaacaattactgg gacaaatttgtgaaacggaaggttatcaacaagtatggagacttatatggagcagagcgc attgcagaacttctgggtttggacaaaagtgcccttgattttagtccagtggaagagagc gaaccagaagaggcatctcttgtgtcatggctaagctccattgatacaaagtaccacatt tggaagcttggagttgttttcactgataactcatttttatacttagcttggtacacaact atgtctatccttgggcactacaacaacttcttctttgctgctcatcttctggatattgct atgggttttaagacattgcgaactattttgtcttcagttactcacaatggcaaacagctt gtgcttactgtgggactccttgctgtagtagtgtacctttacactgtggtcgccttcaac ttcttccgcaaattctacaacaaaagtgaagatgaagatgaaccagacatgaagtgtgat gacatgatgacgtgttacctgttccacatgtatgttggtgtaagagctggtggtggcatt ggagatgaaattgaggatcctgctggagacccttatgaaatgtatcgaattgtctttgac atcacatttttcttctttgtcattgttatcctattggccattattcaaggtctgattatt gatgcttttggtgaattaagagaccagcaagaacaagtgagggaagacatggagaccaaa tgctttatttgtggaatcggcaatgactactttgacacaaccccacatggttttgaaaca catactttgcaagaacataacttggcaaactatttgttcttcttaatgtatctaattaac aaggatgaaactgagcatactggccaggaatcatttgtgtggaagatgtatcaagaaaga tgttgggactttttcccagcaggggactgcttccgtaaacagtatgaggatcaacttggc tag

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