Corvus brachyrhynchos (American crow): 103621473 Help Entry 103621473         CDS       T08418                                  Symbol MDN1 Name (RefSeq) midasin   KO K14572   midasin Organism cbrc  Corvus brachyrhynchos (American crow) Pathway cbrc03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:cbrc00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     103621473 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:cbrc03009]     103621473 (MDN1) Ribosome biogenesis [BR:cbrc03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     103621473 (MDN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_7 AAA_22 AAA_16 TsaE nSTAND3 AAA_18 Sigma54_activ_2 AAA_14 Sigma54_activat ABC_tran AAA_6 bpMoxR Dynein_heavy MDN1_4th DUF815 PduV-EutP MCM VWA Motif Other DBs NCBI-GeneID:  103621473 NCBI-ProteinID:  XP_017598300 LinkDB All DBs Position Unknown AA seq 5552 aa AA seqDB search MVWMHVVADRWSSEPEVWTQQDRQCILNTLAQLLLDKECTVLIGRQVRPILLDLLERNAE AIKAGGQINHDRHERLCVAMSKLVADHPDVLPFALRYFKTTSPVFQRLFLESSDANTVRY GRRRMKLRDLMEAAYRFLQKEQSVFRELWDWSVCVPLLRSHDTLVRWYTSNCLALVTCMN DEHKLSFLKKIFNPEELIHFRLKLLEESQLQNVEKALVLANPDSSFWQKEKELHYAQGHI VSGDLSAHVVAVCGIVLPRLQHVSEEQENNTNSFVLVESAFTNLQNLAIAVAYQTPVLLE GPIGCGKTSLIEYLAAVTGRAKPPHILKVQLGDQTDSKTLLGMYRCTDVPGEFVWQPGTL TQAVTKGHWILLEDIDYAPLDVISVLIPLLEKRELLIPGRGDCLKVAPGFQFFATRRIFS CGGGWYRQQSSHAALLDKYWTKIHLDNMSKGELKEVLQRRYPSLALVTDHLLEIFMDLAG DKYQSPENCAAGSSHTSEAASESRSEHKKPNLEGRELSLRDLLNWCSRIAYNFDSNSSTT AVNIFQEALDCFTAMLSNQGSRQKMAKVIGSYLNISKKKVEFFCELYKPEISIREQEVSV GRVHLVKKQNQALTVQRAKHTFAATRPSAVLIEQLAVCVVKGEPVLLVGETGTGKTSTVQ YLAHITGQRLRVVNMNQQSDTADLLGGYKPVDNKLIWLPLRESFEELFSQTFSRKKNQTF LGHIQTCYRQKRWHDLLKLMQHIHKSAINKEVKENASGLPLKEKWEAFGLKLNHAHQQMK MTENALLFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLSGLLEGSSGSLVLLDRGDT EPLVRHPDFRLFACMNPATDVGKRNLPLGIRNRFTELYVEELRNEGDLQILIMDYLRSLN VNKSTVQGIVNFYLSVRKEAETKLVDGTGHRPHYSLRTLCRALRFAASNPCGSIARSLYE GFCLSFLTQLDRGSHPVVQKLICQHIVSGNIKSLLKQQIPKPQGGSFILIEGYWISAGDK EPTVDESYVLTPSVKLNLKDIVRVVSAGTHPVLIQGETSVGKTSLIRWLAAATGNHCVRI NNHEHTDIQEYIGCYTSDASGKLVFKEGILIDAMRKGYWIVLDELNLAPTDVLEALNRLL DDNRELFITETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSAEL ETILHRRCSLPPSYCSKLVKVMLDLQSYRRGSTVFAGKHGFITLRDLFRWAERYRLAEQL QKEYDWLQHLANDGFMLLAGRVRKQEEVDVIQNVIEKHFKKKIYPESLFSGESVKKLLAK SSTWMSVMDRDFNHVVWTQGMRRLAILVGRALEFGEPVLLVGDTGCGKTTICQIFASLAN QKLYSVNCHLHMETSDFLGGLRPVRQRSKDQEESDGSRLFEWCDGPLVLAMKEEGFFLLD EISLADDSVLERLNSVLEAEKTLVLAEKGGQDDEENEVELLVAGKKFRILATMNPGGDFG KKELSPALRNRFTEIWCPQSNGRDDLVQIVKHNLHPGLSLGAINHEGADIAELMMDFVEW LTKQEFGRQCILSVRDVLAWVNFMNVMVEDESGSAKGCSRLNVSPVMSFIHAACLVYIDG IGSGTTSCSGDMALLARDKCLTFLSEKMSQFFELTDYQKNELKIYDRTKEKEFVWMDNFM GIHPFFIPRGPVLQRNNTTDYALNAGTTAVNAQRLLRALQLNKPILLEGSPGVGKTSLVA ALAKASGNCLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRDGPLLAALKAGHWIVLDE LNLASQSVLEGLNACFDHRAEIYVPELGMNFHVQHKTTKIFGCQNPYRQGGGRKGLPKSF LNRFTQVYVDPLSAEDMKFIGNTLFPAIDKTIIAKMVAFNNKIEKEVMAEKKWGQKGGPW EFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGERMRTREDKEKVISVFRDIFGQEANV YTGTREFHINPYNVQIGYSVLSRGNYIPHSGRTLSLLHHSLQSLEPIMKCVHMSWMVILV GPAAVGKTSLVELLAHLTGHRLKIMAMNSAMDTTELLGGFEQVDINRPWQRLLERVENAV STLIRDSLLLAELCADDAELVLRAWSNFILNYKPKSLGEGGGSVTAELVSKLEGILVLTQ RLNNKINSYTKAEFAYLVEEFRRFKLQQAQAADCNSHGTFEWVDGMLVQALQSGDWLLMD NVNFCNPSVLDRLNALLEPGGVLTMSERGVIDGTIPTITPHPNFRLFLSMDPVHGEISRA MRNRGIEIYVPGETDGNVLDSLDLKLLLHGLGLVGDSVCDALLAVHSETKAAIAGSVSSL SPLLQAAVLIVQQIQRGLGLAKSFYRACWEVYGRSQQLQINQKLVLELVTRHASSLASPD TWGESLLAVGLWPDSLPSGLFAAEDSLLSTVQQDGQVLMYCLHRLNLRNCRTLPVTLQDL KKVMQSTNPESLKFSAVEIDANWMDKMEVLQASVKLFIEKATNQDWKLRVKWLNSLAKNL PQVLDSVRIQLEAGAVALGCFYASPLSSGVSNMIKLLQPTMTDEHVMPLDPRWNMQFLEI IRNSMSFDTEMKHTDQLLILLKSAANRAVLFLDREKRSYIEKNLIASKKPRNSVLRMSLD FHKNPGSYNCLPHGIVVNLAAFFELWDAFALHWVKSNQVALSDNDMHDIFYCSLWRDRFW AVSDTVTVDSPGLSLLALHWHWVMKHLIDRIPQMLIGSDQNKISREIQSVSQQIQSCLVN PSGISANMKILQKSLGRPLPFKDKLGMECFSQLKALSKALNTLELRLAFGESRWQEKMCC VKIAAAGVKMKKALLQADGLIIRANHLEDVSLDQLQIFLKALHSQLKAEGVTYSYSEERL PENTISNKLDPALLNQLCSQVQLWPAMEYIGVLWQYKLTADWLAKACARRNNCSQELSIC SDLAQFIAFSLKLTPAASHQLSGLWHLLHLNEISPEEMSLLSSQLVNAVLASFWSSTFTM DPDYWLTWRPLPATEENSFSKSHVNRSMKGPGILTRAVFSKCFFEILTSSSKTSQWDVSG LPVLSSSHVTLGEWMERAQQLHRVSTALWTNLAVSSIADFRHTDARLQGIMLSRQLSALV DLVPMDLQEEFLECCEKLYIRDPVAYEYLLKILGSITDQELLPKEFLFLLLTCLHQFYGE GLQELPETAWRGSLWVVIGLVQIQMWLPQTRFDPAVKREYKLKYSKEELYQLESEWKTHD FSSQLHTGKSIEDETVSNYIHPHIRLLHERMQRLKEQISSLSRRKAFRPPAPLYDCLYQE AHQYINSIARVSAVQDLLARLLQFLRGERPKSLQAVQSLLNEEASWQQSHHQFRKHLAEE YAAFPDAIIPLQAAIVQLQHGMRLVASEACAMLQSFVCPADLTNLLTSLLAFPSVGHALP TYFARAEILCSVNSVGVLNGLKKFSLKHSEGGSEGTEQPCPTLEQLLVNALLHLRCHVLS RGEMDQKSLQLFRHLCRAIVNEWDEQERRAQEQEAIERSLYRYRSKSHGKGQSEEEEEEE EFRKRFPFHEKDFEDITAQPSLEEKMETEDPVEDQLEINRALLSKSSMQTVMKVHQQLCL NFARSLWYQQSLPSHQAKHYFSTFISCYQTGACLVSQFYPLIGAEMNDSLLGSQLLLSTL LHNTFFEEVASDLVLQQDGPYDFYQHPNIQQVRQCQPVLDNFAKEINRLLQEWPEHPVLV QLLVVMDRIRSFPLSSPLSKFLNGLEILLAKAQDWEENASRALSLRKHLDLVTQLIIQWR RLELNCWSVSLDNIMKQHVEKSTKHWFSIYQMIEKYVQEQTEANTEGTEQMDLKTLVSTL QAFIEGSTLGEFHARLQALLVFHCHVLLLPQVAEKDVLCSILWNLYNYYKQFSECVKAKI TELRQPIEKELKEFVKISRWNDVSFWAIKQSVEKIRRTLFKFMKKFEVVLDEPCRPALVE IGKEEQLDCMQKQEESDDKETKIQRLNNTLRKVLSARTDVTKRALPECQDGITFHTESLQ YRLSKLTKKMKKMCTAVTENNSFLSLVENLDQFTGGIIVSVAELQNLTFDQTATKEKQKS EAKHIQMQKQRALSDLFKSLAKTGLSYRKGLSWSRSKDYQEVLYLRPLDLCSALAAVNCT HELDATLLTEISSAWDGCQKYFYRSLARHSRLQTAFLAPAKDIGLGSIERCKGFTAHLMQ MLVRQRRSLTALTEQWILLRNFLSCIQEIDSRLTADREYNSAFPPQDSIQQWTDRLQQLS MQCVMVLEDLSWFIQCCPKEESARSNESERTDVKPNIFQNSVPEMGNVLAGIPDLIPSDL KHLSPVTTEQLPPGCRMRNKDQLWLQVATQLTATMANVKAMKAEVDRVRQQSRETSFYSW RDFEVCASAVSCLLEVSAQLQSIESLFLPNGQDREAANQMALIKSLKYIQEEVNNTSSDF TAWRTQLLASVSNCSGNQQSDEEFVEQFSTKVETVIRAVLYAVQCLVERKQEGGKEEEKS SEENEDAALLDVVKAGHITKLLDEDLSADLESLHVQKAILGVSELLEILKYYREDCTSYK HKFFNQSCYLLVRLQPMLCKYSDLILFYLTVSLASHRSTGKLLSVLTSIFTELALKGFCL PKELLEDEAGEGATEFHDYEDGGIGEGEGKKDVSDKIESEDQIEDSFRKGEEKEKEDQDS KPDIEGEDNAIEMSEDFEGKMHDGEREKKEDEENSDEEEELDKQMGNLDNAEADDKLDER LWGDEEDDDDEEDASSKTEETGPGMDEEDSELVAKDDNLGIGNKDNKKQPPKNEEKEQQE EDSGNKEKIHEQIDEREYDENEVDPYHGQQEKEPEVEPLDLPDNLNLQSNEKSDDEEDEE EENDFEIDEKPVDLNEAEKTEEQKEEDTGETERDDQDAKAAEEGVSEDKEEKEDEGDKDV HDQEDDAGNTEDAEEEEEESQPPNEKKNESAEDKGIPNEDQGLQPQEEEDKDNSEMDEQI PEAEERMEHETQGQTGQENLQSDSAVELAGEASEKDQSKEESGTGASSANQSEGHESTCM ARMASQKQSRKNTQSFKRKPGQADNERSMGDHNERIHKRLRTMESSSETKQDITQPQQNV EEAEAFEHIKQGSEHYDAQTYDVASKEQEEPIMPPEEKEEGDCEDAAMETEMQDEDLRAV DTEELKPEKKKSTATKPPGPGEVEPEIQTFDLEDVSDSAPEKLPKVTEEKPERSKDSTIH TAHQFLMDTSQHIVRDPEELRKELERQLEAWQTQQPGTPEEEKEAAQLWQRYLVLTAPLS QQLCEQLRLILEPTQAAKLKGDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRQYQ ICLAIDDSSSMIDNHSKQLAYESLAVIGNALTLLEVGQIAVCSFGETVQLLHPFHEQFSD QSGTQILRLCKFQQKKTKIAQFLESSANMFAAAQQLSQNISPETAQLLLIVSDGRGLFLE GKERVTAAVQAARNANIFVIFVVLDNPNSRDSILDIKVPIFKGPGELPEIRSYMEEFPFP FYMILRDVNALPETLSDALRQWFELVTASDTL NT seq 16659 nt NT seq  +upstreamnt  +downstreamnt atggtgtggatgcatgttgtagcagacagatggagcagtgaaccagaagtttggactcag caggatcgccagtgcatcctcaatactttagcacagttattgctggataaagaatgtact gtattgatcggccgtcaagttcggcccatcctgctggatttgttggaaagaaatgcagaa gctattaaagctggtggccagatcaaccatgatcggcatgaaaggctgtgtgtagcaatg agcaagctggttgctgaccaccctgatgttttgccatttgctttaagatactttaaaact acgtcaccagttttccagaggcttttcctggagagctcggatgcaaacacagtccgatat gggcgcagacgaatgaagttacgagacctcatggaggcagcctacagatttttacaaaag gagcagtcagtgttccgggagctatgggactggagtgtgtgtgttccactcctaaggagt catgacactttagtccgttggtatacttcaaactgtcttgcgctggttacatgcatgaat gatgagcataaattatctttcctgaagaaaatattcaatcctgaggagctgatacatttc agactaaagttgctagaagaatctcagctgcagaatgtggaaaaagccctagttttggct aatccagactcctcgttttggcaaaaggagaaggaactgcactatgcacaaggacacatt gtgtcgggcgacctctctgcacacgtagtagctgtctgtggcattgtgctgcctagacta cagcatgtttctgaagagcaggaaaataacaccaacagttttgttttggttgaatctgcc ttcacaaatcttcaaaaccttgctattgctgtagcgtatcagactcctgttttattagaa ggaccaataggatgtggcaaaacctctttaattgaatatttagcagctgttacgggaaga gcaaaacctcctcatattttgaaagttcagcttggagatcaaactgatagtaagacgctg ctgggcatgtatcgatgcacagatgtaccaggggagtttgtgtggcagcctgggaccttg actcaagctgtgaccaaaggtcactggatacttctggaggatattgattatgctcctctg gatgtgatctctgtgctgattcctcttttggagaaaagagagttactgattcctggtcgt ggtgactgtttaaaagtagcaccaggattccaattttttgcaaccagaaggatattcagc tgtggtggaggttggtacaggcagcaaagcagccatgctgctcttctggacaaatactgg accaaaatacatctggataacatgagcaaaggagaactcaaggaggtcctccaaaggaga taccccagccttgctcttgtgacagatcacttgctagaaattttcatggaccttgcggga gacaagtatcagtcaccagaaaactgtgctgctggctccagtcacacatcagaagcagca tcagaatctagatcagaacataagaaaccaaatctggaaggacgagaactatctctaaga gacctactgaattggtgcagcaggattgcttacaactttgacagtaactcttcaaccaca gcagtgaatatttttcaggaggcactggactgtttcacagccatgttgtccaaccaaggg agcagacagaaaatggcaaaagttattggaagttacctaaacatttcaaaaaaaaaggtg gagttcttctgtgaactctataaaccagaaatttcaataagggaacaagaagtctctgtc ggaagagtgcatcttgtgaagaagcagaaccaggctctcactgtacagagggcaaaacat acctttgctgccacacggccatctgcagtattgattgaacagcttgcagtgtgtgttgtc aaaggagagcctgtgcttttggttggtgaaacaggaactggcaaaacttcaacagttcag tacctagctcacattacaggacaacgtttgagggttgtcaacatgaaccaacaaagtgac acagcagatctcttagggggttacaagcctgtggataacaagctgatctggctccctctg cgagagtcttttgaagaactcttctctcagacattctctaggaagaaaaatcaaacattc ttgggacacattcagacttgctacaggcagaagcgttggcatgatctgctaaaactaatg caacatattcataaatctgctattaataaagaagtaaaagaaaatgcatctggcttgcca ctgaaggaaaagtgggaggcatttggtcttaaactgaatcacgctcatcaacagatgaaa atgacagaaaatgctcttctctttgcatttgttgagggtactctagcacaagcagtaaaa aaaggagagtggattttattggatgaaattaacttggctgcagcagagactttggagtgc ctgagtggtttattggaaggatcatctgggtcactggtgttattagacagaggagacaca gagcctcttgtccgtcaccctgattttcgcttgtttgcatgcatgaatccagctacagat gttggaaagagaaatcttcctctaggaataagaaacaggtttactgaactttatgtagaa gaattgagaaatgaaggagacttgcagattcttatcatggattatctgagaagcttgaat gtgaacaaaagcacagtacaaggaattgtgaacttttatttgtctgtgagaaaggaagca gaaacaaagttggtggatggaactggccacagaccacactacagtctccgtaccctgtgc agggcattgagatttgcagcgtctaatccgtgtggcagcatagcgcgctccctgtatgag ggtttctgtttgagtttcctgacgcagcttgacagaggttctcacccagtggttcaaaag ctaatttgccagcatatagtctctggcaacatcaaaagccttctcaagcagcaaatacca aaaccccaaggagggagttttatacttatagaaggatactggatttcagctggggacaaa gaacctacagtagatgagagttacgtgctcaccccttcagttaagcttaatctgaaagac attgtcagggttgtgtctgcagggactcatccagtactgattcaaggagagacctctgtt ggtaaaaccagtttaattcgctggttggctgctgctactgggaatcattgtgtaaggatt aacaaccatgagcatactgatatccaagaatatattggctgttacacatcagatgcctct ggaaagctggtatttaaggaaggcattctcatagatgcaatgagaaagggctactggatt gttctagatgaattgaatttggctcccactgatgttctggaggctctcaaccgcttgttg gatgataacagagagctgttcattactgagactcaggaagttgtcaaagctcaccctcgc ttcatgctgtttgccacacagaaccctccaggtctctatggtggcagaaaggttttgtcc agagccttcagaaatcgttttgtggagctgcattttgatgaactgccaagtgctgaactg gaaaccatcctgcacaggagatgcagtttgccaccttcttactgcagcaagcttgtcaaa gtcatgttagacctgcaatcttaccgcagaggctcgacagtgtttgctgggaagcatgga ttcattaccctgcgggatctgttccgctgggctgaaaggtacaggttggcagaacagctg cagaaggagtatgactggcttcagcacttagcaaatgatggttttatgcttctggcaggc agagtcaggaaacaggaggaggtggatgttattcaaaatgtcattgaaaaacacttcaag aaaaaaatatatcctgagtctctcttctcaggggaaagtgtcaaaaagctactggctaag tcttccacgtggatgtcagtaatggacagagattttaaccatgttgtctggactcaaggg atgaggagacttgccattttggtgggacgagccctggagtttggtgaaccagtactgctg gtgggagacactgggtgtggtaaaactaccatttgtcagatctttgcatcattagcaaat cagaagctgtactcagtgaattgccacctgcatatggagacatcagacttcctgggaggg ctgcgaccagtcaggcagaggtccaaagaccaggaggaatctgatggttctagactcttt gagtggtgtgatggacctcttgttttagcaatgaaagaggaggggttttttctccttgat gagatttctttagctgatgattctgtactagagcgacttaacagtgttcttgaagctgaa aagacattggtacttgctgaaaaaggtggtcaagatgatgaggagaatgaggtagaacta ttagttgcaggaaagaaattccgtatccttgcgaccatgaaccctggaggtgactttggg aaaaaagagctttcccctgcgctgcgcaacagatttacagaaatatggtgcccacagagc aatggccgggatgatttggtacagattgtaaaacacaatcttcatccaggattgtctctg ggtgcaataaaccacgagggggcagacatagcagaacttatgatggactttgttgaatgg ctgactaaacaagagtttggtcgccagtgtattctcagtgtgagagacgtcttggcctgg gttaatttcatgaatgtcatggtagaggatgagtcgggttctgccaagggatgtagccgc cttaacgtttccccagtgatgtcttttatccatgctgcatgtttggtgtatattgatgga ataggatcaggtacaacatcctgctcaggtgacatggctttattagctcgtgataaatgc ctgacattcttaagtgagaaaatgagtcagttctttgagctgactgattatcagaagaat gaactaaagatttatgacagaacaaaggaaaaagagttcgtatggatggacaactttatg ggaattcacccattttttattccaagaggccctgttctccagaggaacaacacgacagat tatgctttaaatgctgggactacagcagtgaatgcacaaagactgttaagagctctacag cttaacaaacctattttgttggagggctcaccaggagtgggcaagaccagcctagttgct gccctggcaaaagcctcaggaaactgtcttgttcgaatcaacctgtctgagcaaacggat gtgacagacttatttggtacagacttgcctgttgaaggtgggaagggaggagaatttgcc tggcgtgatggaccactgttagcagcattaaaggctggacactggattgtgttagatgag ttgaatctggcttctcagtctgtgttagaggggctaaatgcatgctttgaccacagagct gagatttatgttccagaattgggaatgaattttcatgtacagcacaagacgactaagatt tttggatgccagaatccgtacagacaaggaggtggaaggaagggtctccccaagtccttt cttaatagatttacacaggtgtatgttgatccactgtcagcagaagatatgaagtttatt gggaatacattgtttcctgctattgataaaactattattgctaaaatggttgctttcaat aacaagattgaaaaagaagtaatggctgaaaagaagtggggacagaaaggaggaccctgg gagttcaacttacgtgatcttttccgctggtgccagcttatgcttgttgaccaatcccca ggatgttatgatccaggccagcatgtgtttttggtctatggagaaagaatgagaaccaga gaagacaaagaaaaggttatttctgtatttagagacatttttggccaggaggccaatgtg tatacaggaaccagggagtttcacatcaatccatataatgttcagattggttattcagtt ctttctcgtggcaactacattcctcattctggcagaactctctcgcttctgcatcattca ctgcagtccctggagcccataatgaagtgtgtgcacatgagctggatggtgatcctggtg ggcccggcagctgttggcaaaaccagtctggtggagctgttggcccatctcaccggccac cggctgaaaatcatggcgatgaacagcgcgatggatacaactgaactcctgggtggattt gagcaggttgatatcaacaggccatggcagcgccttttggaaagggtggagaatgccgtg agcacactcataagggacagtcttctcctggcagaactttgtgcagatgatgctgaactc gtgctgcgtgcttggagcaatttcatcctgaattacaaacccaaatctctgggggaagga ggtggaagtgttacagctgaattagtgagcaaactggagggaatacttgtacttacccag agactaaacaacaaaataaattcttacacaaaggcagagtttgcttacctggtagaagag ttccgacgtttcaagctgcagcaggcccaggctgctgactgcaacagccatggcactttt gaatgggtggatgggatgttggttcaggctctgcaatctggagactggctgttaatggac aatgttaatttctgcaacccatctgtgctggaccgcttgaatgctttgcttgaaccagga ggtgttctgaccatgagtgagagaggtgtcatagatggcacaattcctacaataactcct catccaaacttcaggctcttcctttctatggatccagttcatggggaaatatccagagcc atgcggaatcgtggtattgaaatttatgttcctggggagactgatggaaatgtattggac agtctggatttgaagttactcctgcatggtttgggtttagttggagatagtgtctgtgat gcacttctggctgtgcattcagaaaccaaggcagcaatagcaggttctgtgtcatcgttg tcacctttgcttcaggctgctgtattaattgtgcagcaaatacaaagaggccttggatta gcaaagtctttttacagagcctgttgggaagtttatggccgctcacaacaactgcagatt aatcaaaagcttgtgttagaattggttacgaggcatgcttcctctctggcttcccctgac acttggggtgagtccttgctagcagtgggattgtggccagactcgctgccttcaggtctg tttgcagctgaagactcgctcctttccacagtccagcaggatggacaggtcctgatgtac tgtctgcacagactaaacctcagaaactgcaggacattaccagtgactctgcaagatctt aagaaagttatgcagtccactaatcccgagagtctcaagttcagtgctgttgagattgat gcaaactggatggacaaaatggaagttctccaggcttcagtgaagttgttcatagaaaag gcgaccaatcaagattggaaattaagagttaaatggcttaactccttagccaaaaatctg ccacaggtgcttgattcagtgcgaattcagctggaagcaggtgctgtagcccttggttgt ttttatgccagtcctctctcatctggagtcagtaacatgatcaagttgctacagccaact atgacagatgaacatgtgatgcctctggacccaagatggaacatgcagtttttggaaatc attagaaattcaatgagctttgatacagaaatgaaacacacagaccagcttcttatcctt ttgaagtctgcagcaaatcgggcagtgttatttcttgaccgagaaaaaagaagttacatt gagaagaatttgattgccagcaagaagccaagaaacagtgtcttaagaatgtctctagat ttccacaaaaatccagggagttacaactgtcttcctcatggaatcgtggtcaaccttgct gctttctttgaactttgggatgcatttgcacttcactgggtgaagtctaatcaggtggcc ttaagtgacaatgacatgcatgatattttctactgctcgctgtggcgggaccggttctgg gcagtgtctgacactgtcacggtggattcgccagggttgtcacttctggctctgcactgg cactgggttatgaaacacctaattgacagaattcctcagatgcttattggatcagaccag aacaagatttccagggaaattcaatctgtttcacagcagattcagagctgcttggtcaat ccttctggtatttcagccaatatgaagatactacagaagtctctaggaagaccccttcct tttaaggataaactgggcatggaatgtttttctcagttaaaagctctcagcaaagcactg aacaccttggagttaagattggcctttggagaaagtaggtggcaagaaaaaatgtgctgt gtgaaaatcgctgccgcaggagtaaagatgaagaaagcattgctgcaagctgatggcctg ataataagagccaatcatttagaagatgttagtctggatcaactacagatatttctgaaa gctctacattcacaactgaaagcagaaggagtcacatacagttattcagaagaaaggctt cctgaaaacaccatctccaacaagttagaccctgccttgctgaatcagctctgcagtcag gttcagctgtggcctgcaatggaatacataggggtgctctggcagtacaaactgacagca gattggctggccaaggcttgtgcaagaaggaataactgcagtcaagaattaagcatatgt tcagatctagctcagtttatagctttttctctgaagttgacaccagctgcttctcaccag ctctctggactgtggcacttgttacaccttaatgaaatatcccctgaagaaatgtctctt ctgtcatctcagctagttaatgctgtgttagcatccttttggagcagtactttcactatg gacccagactactggttgacttggaggccactgcctgcaacagaggaaaacagcttctct aaatcccatgtgaaccgttctatgaagggcccaggcattttgacccgagctgttttctca aagtgcttctttgaaattctaactagcagtagcaagacaagtcagtgggatgtgagtggg cttcctgtcctgtcatcatcccatgtaacactgggagaatggatggagagagcacagcag cttcacagagtcagcacagcgctgtggaccaacctggctgtctcttcaatagcagatttt agacacacagatgctagactgcaaggaataatgctaagcagacagctctctgccctggta gatctggttccaatggatcttcaagaagagtttttggagtgctgtgagaagctctacatc agggatcctgttgcatatgagtaccttctcaagatacttggaagcatcactgatcaggag ctacttcctaaagaatttctgtttcttctgctcacgtgcttgcatcagttctatggggaa gggcttcaggagttaccagagacagcttggcgaggaagcctctgggtggtcattggcttg gtgcagatccagatgtggcttccacagaccaggtttgatccagctgttaaaagagaatac aagctcaagtactcaaaagaagagttataccagctggagagtgaatggaaaacacatgac ttttcatcccaactgcatacaggaaaaagtattgaagatgaaacagtcagcaactatatt catccccatatcagactgttgcatgaaagaatgcaaaggttgaaagagcagataagcagc ctttctagaaggaaggccttcaggcctccagctccactgtatgattgcttgtaccaggag gctcaccagtacatcaatagcatagcacgggtttccgcagtccaagaccttctagcccgc cttctgcagttcctccgtggagagagacctaaatcactgcaggctgtacagagcctgtta aatgaagaagcatcgtggcaacagtcacaccatcagtttagaaaacacctggcagaggag tatgctgcattccctgatgccatcattccgctccaagctgccatcgtgcagctgcaacat ggcatgcggttagtggcttctgaagcgtgtgcaatgctgcagagctttgtgtgcccagct gatctcaccaacctcctcacttctttgttggcatttccttctgttggccatgcccttcct acttactttgctcgggcagaaattttatgctcagtgaattcagttggggtacttaatgga cttaaaaagttctctctgaagcactctgaaggaggatctgagggaactgaacagccttgc ccaactctggaacaactcctggtgaatgctttgttgcatcttcgatgccatgtactatcc agaggagagatggaccagaaatctctgcagctcttcagacatctgtgtcgggcaattgta aatgaatgggatgaacaggaacgccgtgcccaagagcaggaggcaatagaacgcagcctg tacagatacaggagtaaaagtcatgggaaaggacagagtgaggaagaagaggaagaagaa gaatttaggaagagatttccttttcatgaaaaggactttgaagatatcacagctcagcca agcctagaagaaaaaatggaaaccgaagatccagtggaagaccagctggaaattaacaga gcccttttgtccaagagctctatgcaaacagtaatgaaggttcatcaacagttgtgctta aactttgctcgatccctgtggtatcaacagagtctgccttctcatcaggccaagcattat tttagtacatttatttcctgctatcagactggtgcatgcctggtgtcacaattctatcct ttaattggtgctgaaatgaatgacagtcttttgggaagccaacttctgcttagcactctt cttcacaataccttttttgaggaagtagcttcagatcttgtgctgcagcaagatggccca tatgacttctaccagcatcccaatattcagcaagtccgacagtgccaacctgtacttgac aattttgctaaagaaataaataggctactgcaggaatggccagagcatcctgtacttgtg cagctgttagttgtgatggacagaatccggagttttccactttctagtcctctctcaaag tttctgaatggcttggagattcttcttgcaaaggcacaggactgggaggaaaatgctagt cgagccttgtccttgcggaagcatcttgatctggtcacacaactgattattcagtggcgt agattggagttgaattgctggtcagtaagtttggacaatattatgaagcagcatgtggag aaatccacaaagcactggttctcaatctatcagatgattgagaagtatgttcaagaacag acagaggcaaacacagaaggaactgagcaaatggatctgaaaacgctggtcagcacctta caggctttcattgaaggctctactctgggagagtttcatgcacggctccaagcactattg gtttttcactgccatgtattgctgttgcctcaagtagctgaaaaggatgttctgtgcagc atcctgtggaatctatacaattactataagcagttttcagagtgtgtcaaggccaaaatc actgaacttcgtcaacccatagaaaaggaacttaaggaatttgtgaagatttccaggtgg aatgatgtcagcttctgggctataaagcaatcagttgaaaaaatacggagaaccctcttt aaattcatgaagaagtttgaagttgttctggatgagccatgtcggcctgccttggtggaa attggtaaggaagagcagctggactgcatgcaaaagcaagaagaatctgacgacaaagaa accaaaattcagaggctaaacaacacattaagaaaggttctgtctgctagaacagatgtt accaagagggcactcccagaatgtcaggatggcattacatttcatacagaatctcttcag tatcgtctgtctaagcttactaaaaaaatgaagaaaatgtgtacagcagttacagaaaat aattcattcctaagcctggtggaaaatctcgaccagttcacaggtggtattattgtttct gtagctgaactgcaaaatttaacatttgaccagacagcaactaaggaaaagcagaaatcc gaggcaaaacatattcagatgcaaaagcaacgggctttgtcagatctctttaaaagcctt gctaaaacaggtttgtcgtaccggaaaggtctgtcttggtcccgttccaaagactaccag gaagttctctaccttcgtccactggacttgtgtagtgcattggctgcagtgaattgtaca catgaactggatgccacgttgctgacagagatttcttctgcctgggatggatgccagaag tacttctatcggtcacttgcacgtcactctcggctccagacagcattcttagcacctgcc aaggatattggactaggtagcattgaacgatgcaaagggttcactgcacacctcatgcag atgcttgtgagacagaggcgatctcttactgcattgacggaacagtggatcttactgagg aacttcctgagttgtatacaagagatagattctaggttgactgctgacagagaatacaat tcagcatttcctcctcaagacagtattcaacaatggacagacagactgcagcaactttcc atgcagtgcgtgatggttcttgaggatctgtcttggtttatccagtgctgcccaaaagaa gagtcagccaggtccaatgagagtgaaaggaccgatgtcaaacccaatatttttcagaat tcagtacctgaaatgggaaatgttcttgcaggaatacctgacctgattccctcagatcta aaacacttgtctccagtaacaactgagcaattgcctcctggatgcagaatgcgaaataag gatcagctgtggctgcaggtagctacacaactgactgcaacgatggcaaatgtaaaggcc atgaaagcagaagtggacagagtaagacaacagtcacgtgagacctccttttattcctgg agagactttgaggtttgcgcatcagctgtgagttgtttgctggaagtctcagcccagtta caaagcatagagtccctgtttcttccaaatgggcaagacagggaagctgcaaatcagatg gccctcatcaagagcctgaagtatatacaagaagaagttaataacacgtcttcagacttc acagcctggagaacacagcttcttgcttctgtgtcaaattgcagtggaaatcaacagtcg gatgaagaatttgtggagcaattctcaacaaaagtggagactgttatccgtgctgttctg tatgctgttcagtgtttggtagagagaaaacaggaaggtggaaaagaggaagaaaaatct tcagaggaaaatgaggatgcagccttacttgatgtggttaaagctggacatataactaaa cttttggatgaagatctgtctgctgatttggagtccctacatgtgcagaaggcaatttta ggtgtttcagagctcctggagatcctgaaatattacagggaagactgtacttcatataaa cataagttcttcaaccagtcctgctatttgctggtgcgtctacagcccatgctctgcaag tactcagacctcatcctgttctacctcaccgtttcactggcatctcacaggagtactgga aaattgctttctgttctaaccagcatttttacagagcttgccctaaaggggttttgtctg ccaaaagaattacttgaagatgaagcaggagagggagcaacagagttccatgattatgag gatggtggtattggagaaggggaaggcaagaaggatgtgagcgacaaaatagaaagtgaa gatcagatagaagacagttttcgaaagggtgaagagaaggagaaagaggatcaagattct aaaccagacattgaaggagaagacaacgcaattgaaatgtctgaagactttgaaggaaag atgcatgatggagaacgggagaaaaaagaagatgaggaaaattcagatgaagaggaggaa ctggataagcagatgggcaatcttgataatgctgaagctgatgataaactagatgaaagg ctctggggggatgaagaagatgatgatgatgaagaagatgctagtagtaaaacagaagaa actggaccaggaatggatgaggaggattcagagcttgttgcaaaagatgacaatttgggg ataggaaacaaggataataaaaaacaacctcccaagaatgaggaaaaagagcaacaggaa gaggacagtggaaataaagagaaaatccatgaacaaattgatgagcgtgagtatgatgag aatgaagtagatccgtatcatggccagcaagaaaaggagcctgaagttgaacctttggac cttcctgataatttgaatctgcagagtaatgagaagagtgatgatgaggaggatgaagaa gaagagaatgattttgaaatagatgagaaacctgtggatttaaatgaggcagagaagaca gaagaacagaaggaagaggatactggtgagacagaaagagatgatcaggatgcaaaagca gctgaagaaggcgtttctgaagataaagaggagaaggaagatgaaggagacaaagatgtt catgatcaagaagatgatgcagggaacactgaggatgcagaagaagaagaggaagagtca caaccacctaatgagaaaaaaaatgaatctgccgaagataagggaatccctaatgaagac caaggccttcaacctcaggaagaggaggataaagataattcagagatggatgaacagatt cctgaggctgaggaaagaatggagcatgaaacacaagggcagactgggcaagaaaatctg cagagtgacagtgctgttgagctggctggagaggcttcagaaaaagaccagtctaaagag gaaagtggaactggagcttcaagtgcaaatcagtcagaaggccatgaatccacatgcatg gcccggatggcttctcagaagcaaagcaggaaaaatacacagagtttcaagaggaaacct ggccaggcagacaatgagcgctcaatgggagatcacaatgaacgcatccacaagcgactg agaaccatggaatccagcagtgaaacaaagcaggatataactcagcctcaacaaaacgtg gaggaggctgaagcatttgaacatattaaacaaggctctgaacactatgatgcacagaca tatgatgtagctagcaaggagcaagaggaacctattatgcctcctgaggaaaaggaagaa ggagactgtgaagatgcagcaatggaaacagaaatgcaggacgaggatctcagagcagta gacactgaggagctgaagccagaaaaaaagaagtctactgccactaaacctcctggacca ggtgaggtggagccagagatccagacttttgacttggaggatgtcagtgactctgcacca gaaaagctaccaaaggtgactgaagagaagccagagcgaagtaaggactcgaccatacac acagcccaccagtttctgatggacacttcccagcacattgttagagatcctgaagagcta agaaaggaacttgaaaggcaattggaagcttggcagacacaacagcctggaactccagag gaggagaaggaagcagcgcagttgtggcagaggtatttagtactgacagctcctctgtca cagcagctttgtgaacagctgcgactcatactggaacccactcaggctgccaagctgaaa ggagactacagaacagggaagagactgaacatgcgcaaagtgatcccgtacattgccagt cagttccgaaaagacaagatctggctgcgaaggaccaagcccagtaaacgacagtaccag atttgcctggctattgatgattcctctagtatgattgacaatcactctaaacagcttgct tatgaatccctagcagttattggaaatgctctgactcttctagaagtgggacaaattgct gtgtgtagctttggagagactgttcagctgctgcacccattccatgagcagttcagtgac cagtcagggacacagatattgcgtctttgcaagtttcagcagaagaaaacaaaaatagct cagtttctagaatcatcagcaaatatgtttgctgcagcacagcagttgtctcaaaatatt agtccggaaacggcacagctgcttctgattgtatctgatggaagaggccttttcttggaa ggcaaggaacgggtgacagcagcagttcaagcagctcggaatgccaatatctttgttatt ttcgtagtgttggacaatcctaattcccgggattctattttggacattaaagtacccata ttcaaaggacctggagaactgcctgaaatcaggtcttacatggaagaattcccattcccg ttctacatgatccttagagatgtgaacgcgctcccagaaactctgagtgatgccctcaga cagtggtttgaactggtgactgcctctgacactctttag

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