Clostridium botulinum E3: CLH_0303
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Entry
CLH_0303 CDS
T00767
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
cbt
Clostridium botulinum E3
Pathway
cbt00290
Valine, leucine and isoleucine biosynthesis
cbt00660
C5-Branched dibasic acid metabolism
cbt01100
Metabolic pathways
cbt01110
Biosynthesis of secondary metabolites
cbt01210
2-Oxocarboxylic acid metabolism
cbt01230
Biosynthesis of amino acids
Module
cbt_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cbt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CLH_0303 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CLH_0303 (leuC)
Enzymes [BR:
cbt01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CLH_0303 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CLH_0303 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Met_synt_B12
Motif
Other DBs
NCBI-ProteinID:
ACD51338
UniProt:
B2UYH6
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All DBs
Position
305239..306498
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AA seq
419 aa
AA seq
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MGMTMTQKILASHAGLESVKAGQLIEVNLDLVLGNDITTPVAINEFKKFGVDKVFNKSQI
AIVPDHFTPNKDIKAAEQVKYVREFSNKMGIENFFEVGEMGIEHCLLPEKGLVVAGDVVI
GADSHTCTYGALGAFSTGIGSTDMAAGMATGQTWFKVPSAIKFILKNKPAKWVSGKDIIL
HIIGMIGVDGALYKSMEFVGDGLNYLSMDDRFTMANMAIEAGGKNGIFPVDDKTVEYLKE
HTEKEWKIYEADEDAEYDEVIEIDLSTLKPTVSFPHLPDNTRTIDNANRVNIDQVVIGSC
TNGRISDLRIARGILKGKKVKKGIRCIVIPGTQKIYLQALEEGIIKDLIEAGAVVSTPTC
GPCLGGHMGILAKGERCVSTTNRNFVGRMGHVESEVYLASPAVAAASALTGKITDPELV
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atggggatgacaatgactcaaaaaatattagcgtcacatgcagggttagaaagtgtgaaa
gcaggtcaattaatcgaagtaaatcttgatttagttttaggaaatgatattacaacacca
gtagctataaatgaatttaaaaaatttggtgttgataaagtctttaataaaagtcaaatt
gcaattgtaccagatcactttactccaaataaagatataaaagcagctgaacaggtaaag
tatgttagagaattttctaataagatggggatagaaaatttctttgaagtaggagaaatg
ggaatagagcattgtttacttcctgaaaaaggactagttgttgcaggggatgtggttatt
ggggctgattctcatacttgcacatatggtgctcttggagcattttcaactggaataggt
tcaactgatatggcagcaggaatggctactggacaaacttggtttaaagttccgtcagct
ataaaatttattcttaaaaataaaccagctaaatgggttagtggaaaagatattatttta
cacataataggaatgataggtgttgatggagctttatataaatcaatggagtttgttgga
gatggattaaattatctttccatggatgatagatttacaatggctaatatggcaattgaa
gcaggtggaaaaaatggaatattcccagtagatgataagactgttgaatatttaaaagaa
catacagaaaaagaatggaagatctatgaagcagatgaagatgcagaatatgatgaagtt
atagaaatagatttaagcacactaaaacctacagtttcatttcctcatttacctgataat
acaagaactattgataatgctaatagggtaaatattgaccaagtagttattggatcttgt
acaaatggaagaatatcagatttaagaatagcaaggggtattttaaaaggtaaaaaggtt
aaaaaaggaattagatgcatagttatcccaggaactcaaaaaatttatttgcaagcatta
gaagaaggtattattaaagatttaattgaagcaggagcagtggtttcaacgccaacttgt
ggcccatgtttaggtggtcatatggggatattagcaaaaggagaaagatgtgtttcaaca
acaaatagaaattttgtgggtagaatgggtcatgttgaatcagaagtatatcttgctagt
ccagcagtagcggcagcatcagctttaacaggaaaaataactgatccagagttagtgtaa
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