Clostridium botulinum E3: CLH_1037
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Entry
CLH_1037 CDS
T00767
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cbt
Clostridium botulinum E3
Pathway
cbt00230
Purine metabolism
cbt01100
Metabolic pathways
cbt01110
Biosynthesis of secondary metabolites
Module
cbt_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cbt00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CLH_1037
Enzymes [BR:
cbt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CLH_1037
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ACD54036
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Position
1089135..1092881
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AA seq
1248 aa
AA seq
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MLNIKSIFVEKKSGFDVEAQGLLRDFKENLGVANLENVRLINKYIISDISDEYYNKALHT
IFSELTVDNIYESELPINEDEIAFAVEFLPGQYDQRADSASECISLLTEEDKAYIKSAKI
IVLKGNINKEEIDKIKLYYINPVDSREVDINSKDITSTSNIPKDVLILNGFIEKSLEELQ
EFHSDYGLAMSIEDLVMIKDYFKKENRDPSITEIRVIDTYWSDHCRHTTFSTILENIEFE
DNKYTKPIKKSYENYMKSREYVYGEKEKEKTLMDIAVIAMKELRKRGKLDDLDISEEINA
CSINVKIETNNGLEDYLVMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRTYVYQAMR
VTGAGDPTVSIEETLKGKLPQRTITLGAAHGYSSYGNQIGLATGQVQEIYHPNYVAKRME
VGAVIAAAPKENVVREEPKLGDVIILLGGRTGRDGVGGATGSSKEHTIDSLNECGAEVQK
GNAPTERKIQRLFRNSKVAKMIKRCNDFGAGGVSVAIGELCRGLDIDLDKVTKKYEGLDG
TELAVSESQERMAVIVTKENADEFIRLSNEENLEATLVAHVTDTDKLRLYWRGKKIVDLD
RSFLDTNGASQKVSVKVNGPTQYPYEVYDVNVKDTWINNLKDLNIASQKGLVERFDSTIG
AGTVIMPFGGKYANTPAEGMAAKIPVLGGESKDATIMTFGFNPYLGTWSQYHMAYYSVIE
SITKLSAMGGDYRKARLTFQEYFEKLGKDETRWGKPFAALLGAYEAQMQLGIAAIGGKDS
MSGSFGELDVPPTLVSFAVGIEKASKIISPEFKGVNSKLVLLKTEKLEDGTIDMNKFKKN
LEVLYKLIEEEKVISASAVKFGGVAECLTKMSLGNRIGTEFNNLTKDELFGFNYGSLLLE
VKNEIDINEEFKDCLYKEVGKTISSQKIISKEYDLKLDIENLEEIYEKKLNSVFKIKTED
VSQKIETVLYEKKEISSPAIKLAKPRVVIPVFPGNNCEYDCRRAFEKEGAKVSEVVFRNI
TKEALVESIERLKSEIDKSQIIMIPGGFSAGDEPDGSGKFIATVLRNEKIKESVMELLKN
RDGLALGVCNGFQALIKLGLVPYGEIVDIKEDMPTLTYNNINRHMSSIVRTKVVSNKSPW
FNEVNVGDIHSIAISHGEGRFVAPESLIKELINNGQVATQYVDLQGDVALNMPYNPNGSM
YGIEGITSPDGRVLGKMAHSERIGENLYRNIPGNFDQKIFRSGVNYFK
NT seq
3747 nt
NT seq
+upstream
nt +downstream
nt
atgttaaatattaagagtatattcgttgaaaagaaaagcggatttgatgtagaagcacag
ggcttactaagagattttaaagaaaatttaggagtagctaatttagagaatgtaaggctt
ataaataaatatattatttcggatataagtgatgagtactataataaagcactacatact
attttttcagaattaacagttgataatatttatgaatcagaattgcctataaatgaagat
gaaatagcctttgcagtagaatttttaccaggacaatatgatcagagagcagattcagct
tcagaatgtatatcattattgactgaagaagataaagcttatataaaatcagctaagata
attgtgttaaagggaaatattaataaggaagaaattgataaaataaaattatattatata
aacccagtcgattcaagagaagtggatataaatagtaaagacattacatcaacttcaaac
atacctaaagatgttcttatattaaatggattcatagaaaaaagtttagaagaattacaa
gaatttcattcagattatggtcttgctatgagtattgaagatcttgttatgataaaagac
tattttaaaaaagaaaatagagatccatcaatcactgaaatcagagttatagacacttat
tggtcagatcactgtagacatactacattttctacaatattagaaaatatagagtttgaa
gataataaatatacaaaaccaattaaaaaaagctatgaaaattacatgaaatctagagaa
tatgtatatggagaaaaagaaaaagaaaaaactcttatggacattgcagttatagcaatg
aaagaacttagaaaaagaggaaagcttgatgatttagatatatcagaagaaataaatgca
tgctctattaatgtaaaaattgaaactaataatggattagaagattatctagttatgttt
aaaaatgaaactcataaccatcctactgagattgaaccttttggtggagccgcaacttgt
ttaggtggagcaataagagatccattatcaggtagaacatacgtgtatcaagctatgaga
gttacaggagctggtgatccaacagtttcaattgaagaaactttaaaaggaaaacttcct
caaagaactataactttaggagcagcacatggatatagctcttatggtaatcaaataggt
cttgcaactggacaagttcaagaaatttatcatcctaattatgtagcaaaaagaatggaa
gttggagcagttattgcagcggcaccaaaagaaaatgttgttcgcgaagaaccaaaatta
ggcgatgtaattatcttacttggaggaagaacaggtagagatggagttggtggagcaaca
ggatcatcaaaagaacatacaatagattcacttaatgaatgtggagcagaagttcaaaag
ggaaatgctcctactgaaagaaaaattcaaagattatttagaaattcaaaagtagccaaa
atgattaaaagatgtaatgattttggtgcaggtggggtttcagttgctattggagaatta
tgcagaggattagatatagatttagataaagtaacaaaaaaatatgagggattagacggg
acagaacttgcagtttcagaatcacaagaaagaatggcagtgattgtaacaaaagaaaat
gcagatgagtttattagactttcaaatgaggaaaatctagaagcaacattagtagctcac
gttacagatactgataaacttagattatactggagaggcaaaaaaatagtggatttagat
agaagctttttagatacaaatggagcaagtcaaaaagtatctgttaaggttaatgggcca
acacagtatccatatgaagtttatgatgtaaatgtaaaagatacatggataaataactta
aaagatttaaatatagcatctcaaaagggactagtcgaaagatttgattcaactattgga
gcaggaacagtaattatgccttttggaggtaaatatgcaaacactccagctgaaggaatg
gcagctaaaattccagtgcttggtggggaaagcaaagatgctacaataatgacttttgga
tttaatccatatctaggaacttggagtcaatatcatatggcatattactcagtaatagaa
tcaataacaaaactttcagctatgggtggagattatagaaaagctagattaacttttcaa
gagtatttcgaaaaactaggaaaagatgaaacaagatggggaaagccatttgcagcacta
cttggagcttatgaagcacaaatgcaacttggaattgcagcaattggaggaaaagattca
atgtcaggaagctttggagagttggatgtacctccaacattagtttcattcgcagttgga
attgaaaaagctagcaaaataatatctccagaatttaagggtgtaaattcaaaattagtg
ttacttaaaactgaaaaattagaagatggcactatagatatgaataagtttaaaaagaat
ttagaggttctttataaattaatagaagaagaaaaagttatttccgcatctgcagttaaa
tttggcggtgttgctgaatgtttaactaagatgtcacttggaaatagaatcggtacagag
tttaataatttaactaaggatgagttattcggatttaattatggaagtttattattagaa
gttaaaaatgaaattgatataaatgaagaattcaaagattgtttatataaagaagtaggt
aaaacaatctcttctcaaaaaataatatctaaagaatatgacttgaaattagatattgaa
aatttagaagaaatatatgaaaaaaaattaaatagcgtatttaagataaaaactgaagat
gtttcacaaaagatagaaactgttttatatgagaaaaaagaaatttcatcaccagctatt
aaattagctaaaccaagagtcgtgattccagttttcccaggaaataattgtgaatatgac
tgtagaagagcttttgaaaaagagggggctaaggtttcggaagtagtatttagaaatatt
acaaaagaagcattagtagaatcaatagaaagacttaaatctgagatagataaatctcaa
ataataatgattccaggaggattctcagcgggagatgaaccagatggatcaggtaaattt
atagcaactgtgcttagaaatgaaaagattaaagaatcagtaatggaattattaaagaat
agagatggattagctttaggagtttgtaatggcttccaagctttaattaaattaggatta
gtaccgtacggtgaaattgttgatataaaagaagatatgcctacattaacttacaacaat
ataaatagacatatgtcttcaatagttagaacaaaagtggtttctaataaatcaccatgg
tttaatgaagtaaatgtaggagatatacattcaatagcaatttctcatggagaaggaaga
tttgttgcacctgaaagtttaataaaagaattaataaataatggacaagtagcaactcaa
tatgttgatcttcaaggcgatgtggcacttaatatgccatataatccaaatggatcaatg
tatggaattgaaggaataacaagtccagatggaagagtacttggaaaaatggctcattca
gaaagaataggtgaaaatttatatagaaatattccaggaaactttgatcaaaagatattt
agatcaggagttaattactttaagtaa
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