Clostridium botulinum E3: CLH_1518
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Entry
CLH_1518 CDS
T00767
Symbol
gshAB
Name
(GenBank) glutamate--cysteine ligase/gamma-glutamylcysteine synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
cbt
Clostridium botulinum E3
Pathway
cbt00270
Cysteine and methionine metabolism
cbt00480
Glutathione metabolism
cbt01100
Metabolic pathways
cbt01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cbt00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CLH_1518 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
CLH_1518 (gshAB)
Enzymes [BR:
cbt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
CLH_1518 (gshAB)
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
ATP-grasp_3
Dala_Dala_lig_C
GARS_A
DUF4110
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
ACD52195
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Position
1628677..1630980
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AA seq
767 aa
AA seq
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MLKYIKEKVTINQLLKANYGIEREMLRVNEEGQLSLKEHPKVFGDKINNPYITTDFSESQ
IEMITPVFDTVEEVHKFISSLYDIVSQEIGEEYLWPQSMPCLIPDGSEIPIAKYNEGSKG
KEAKLYREKLIHKYGGKKQLISGIHYNFSFNEELIKVLYKEYGVKGTYKTFKNNIYLKVA
RNYLRYRWLIIYLLGASPVLHDTYMENNKNEFKKIGSDTLSNNKATSYRNGKYGYRNNIE
LFPNYHSVDDYIESLKAFVNDGVIDSYKELYSQIRLKPKNNDDFFNSLLDDGINYLEYRT
IDVNPFEKSGIALDDLYFLQIFNIFLLLKEESDYETWQQEALENQNIISNFGQSNAELKR
DGTSISKDKWALELLEEIKNLNSELKLGKENVIDSMIDKVNNSNLTYSYRILEKIKNQGY
VNGFLNLSKKYKKDAYNNRFKFNLYEDLELSTQILIKEAIKRGIKFNIIDRIDNFISLQK
GAKVEYIKQATKTSKDNYISVLIMENKVVTKKVLENNSINVPRGYEFTSLDEAISMVEEF
INRPIVVKPKSTNFGIGISIFTEKSHKEDVICALKIAFKHDDTVLVEEFIRGKEYRFLVI
NDEVEGILHRVPANVIGDSVSSIRTLVEIKNQDPLRGYHYRTPLEKINLDENARLFLKQQ
NKDFDYIPKKDEIVYLRENSNISTGGDSIDYTDDIPEKFKNIAIQCAKAVNAKICGVDMI
IEDYRDENSQYAIIELNFNPAIHIHSYPYKGTERNIAVKILDLLGFI
NT seq
2304 nt
NT seq
+upstream
nt +downstream
nt
atgttaaagtatattaaagaaaaagttactataaatcaattgttaaaagcaaattatgga
attgaaagagaaatgttaagagttaatgaagaaggacagctatcattaaaggaacatcca
aaagtttttggagataagataaataatccttatataaccactgatttttcggaaagccaa
atagaaatgataactccagtatttgatactgtagaggaagttcataaatttataagttca
ctttatgatattgtatcgcaagaaattggagaagaatatttatggccacaatctatgcca
tgcttaattcctgatggaagtgaaatacctattgctaaatataatgaaggttctaaagga
aaagaagcaaaactatacagagaaaaattaatacacaaatacggaggaaaaaaacaactt
atttctggcatacattataacttttcatttaatgaggaactaataaaagtcttgtataaa
gagtatggggtaaaaggtacttataaaacttttaaaaataatatttatctaaaagttgca
agaaattatcttagatacagatggctaataatataccttttaggagctagtcctgtttta
catgatacatatatggaaaataacaagaatgaatttaaaaaaataggatcagacacatta
tctaataataaagctacatcttatagaaatggaaaatatggatatagaaacaatatagag
ctatttccaaattatcatagtgtagatgattatattgaaagcttaaaagcatttgtaaat
gatggggttattgatagttataaggaattatatagtcaaataagattaaagcctaagaat
aatgatgatttttttaattctctactagatgatggaataaactatttggaatatagaact
atagatgtaaatccttttgaaaagagcggtatagctttagatgatttatattttcttcaa
atatttaatatatttttattattaaaagaagaaagtgactatgaaacttggcaacaagaa
gcattggaaaatcaaaatattatatcaaattttggacaaagcaatgctgaattaaaaaga
gatggaacatctatatcaaaagataaatgggcattagaattgttagaagagattaaaaac
ttaaatagtgaacttaaacttggaaaagaaaatgttatagattctatgattgataaagtt
aataatagtaatcttacatattcatataggatacttgaaaaaataaaaaatcaaggatat
gttaatggatttttaaacttatcaaagaaatataaaaaagatgcatataataatagattt
aaatttaatctatatgaagatttagaattatctactcaaattttgataaaagaagcaata
aaaagaggtattaaatttaatattatagatcgaatagataattttatttcacttcaaaaa
ggtgcaaaggtagagtatataaaacaagcaactaaaacatcaaaagacaattatattagt
gttttgataatggaaaataaagtggttacaaaaaaagtacttgaaaataatagcattaat
gtaccaagaggatatgagtttacatcattggatgaagctataagtatggtagaggaattt
atcaatagaccaatagttgtaaaacctaaatctactaattttggtataggaataagtata
tttacagaaaaaagccataaagaagatgttatatgtgcattaaaaatagcatttaagcat
gatgatacagtcttagtagaagaatttataagaggaaaagaatatagatttctagtaata
aatgatgaagttgaaggaatattacatagagtgccagctaatgttattggtgatagcgta
agtagtataagaactttagtagaaataaaaaatcaagatccattaagaggatatcattat
agaacaccattagaaaaaataaatttagatgaaaatgcaagattatttcttaaacaacaa
aataaagactttgactatatccctaaaaaagatgaaatagtatatttaagagaaaattct
aatataagtacaggaggagatagtatagattatactgatgatataccagaaaaatttaaa
aatatagcaatacaatgtgcaaaagcagtaaatgcaaaaatatgtggagttgatatgatt
atagaagattatagagatgaaaattcacaatatgcaataattgaacttaattttaatcca
gcaatacatattcattcttatccatataaaggcacggaaagaaatatagctgtaaaaata
ctagatttattagggtttatttaa
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