Cervus canadensis (wapiti): 122419806
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Entry
122419806 CDS
T07554
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00020
Citrate cycle (TCA cycle)
ccad00480
Glutathione metabolism
ccad01100
Metabolic pathways
ccad01200
Carbon metabolism
ccad01210
2-Oxocarboxylic acid metabolism
ccad01230
Biosynthesis of amino acids
ccad04146
Peroxisome
ccad05230
Central carbon metabolism in cancer
Module
ccad_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ccad_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
122419806 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
122419806 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
122419806 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122419806 (IDH2)
Enzymes [BR:
ccad01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
122419806 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
122419806
NCBI-ProteinID:
XP_043290567
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Position
17:46463512..46479639
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AA seq
452 aa
AA seq
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MAGYLRVVRSLCRASGSGSAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKHKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKSNLDKALGQQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggctggttacctgcgggtcgtacgctcgctctgcagagcctctggctccgggtcggcc
tgggcgccagcagccttgacagcccccaacttgcaagagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccagtggtggagatggacggtgatgagatgacccgt
attatctggcagttcatcaaggaaaagctcatcctgccccacgtggacgtccagctcaag
tatttcgacctggggctcccgaaccgtgaccagaccaatgatcaggtcaccatcgactcc
gcgttggccacccagaagtacagtgtggctgtgaagtgtgccaccatcacccccgacgag
gcccgtgtggaagagttcaagctgaagaagatgtggaagagccccaatggaaccatccgg
aacatccttgggggaactgtcttccgggagcccatcatctgtaagaacatcccgcgtctt
gtccctggctggaccaagcccatcaccattggcaggcatgcccacggcgaccagtacaag
gccacagactttgtggttgaccgggctggcacattcaaggtggtcttcaccccgaaagat
ggcagcggccctaaggaatgggaggtgtacaactttcccgctggtggcgtgggcatgggc
atgtacaacacggatgagtccatctcaggttttgcacacagctgcttccagtatgccatc
cagaagaagtggccgctttacatgagcacgaagaacaccatcctgaaagcctacgacggg
cgcttcaaggacatcttccaggccatctttgagaagcactataagactgagttcgacaaa
cataagatctggtatgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcgggcggctttgtgtgggcctgcaagaactatgacggagacgtgcagtcggacatcctg
gcccagggctttggctcccttggtctgatgacgtctgtgctggtctgtccggatgggaag
accattgaggctgaggctgctcatggcacggtcacccgccactatcgggagcaccagaag
ggccggccgaccagcaccaaccccatcgccagcatctttgcatggacgcgtggcctggaa
caccggggcaagttagacgggaaccaggacctcatcaggttcgcccagaccctggagaag
gtatgtgtcgagacggtggagagcggagccatgaccaaggacctggcaggctgcatccac
ggcctcagcaatgtgaagctgaacgagcacttcctgaacacctcggacttcctggacacc
atcaagagcaacctggacaaagctctgggccagcagtag
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