KEGG   Cervus canadensis (wapiti): 122422203
Entry
122422203         CDS       T07554                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad04010  MAPK signaling pathway
ccad04020  Calcium signaling pathway
ccad04022  cGMP-PKG signaling pathway
ccad04114  Oocyte meiosis
ccad04218  Cellular senescence
ccad04310  Wnt signaling pathway
ccad04360  Axon guidance
ccad04370  VEGF signaling pathway
ccad04380  Osteoclast differentiation
ccad04625  C-type lectin receptor signaling pathway
ccad04650  Natural killer cell mediated cytotoxicity
ccad04658  Th1 and Th2 cell differentiation
ccad04659  Th17 cell differentiation
ccad04660  T cell receptor signaling pathway
ccad04662  B cell receptor signaling pathway
ccad04720  Long-term potentiation
ccad04724  Glutamatergic synapse
ccad04728  Dopaminergic synapse
ccad04921  Oxytocin signaling pathway
ccad04922  Glucagon signaling pathway
ccad04924  Renin secretion
ccad05010  Alzheimer disease
ccad05014  Amyotrophic lateral sclerosis
ccad05020  Prion disease
ccad05022  Pathways of neurodegeneration - multiple diseases
ccad05031  Amphetamine addiction
ccad05152  Tuberculosis
ccad05163  Human cytomegalovirus infection
ccad05166  Human T-cell leukemia virus 1 infection
ccad05167  Kaposi sarcoma-associated herpesvirus infection
ccad05170  Human immunodeficiency virus 1 infection
ccad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122422203 (PPP3CA)
   04310 Wnt signaling pathway
    122422203 (PPP3CA)
   04370 VEGF signaling pathway
    122422203 (PPP3CA)
   04020 Calcium signaling pathway
    122422203 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    122422203 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    122422203 (PPP3CA)
   04218 Cellular senescence
    122422203 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    122422203 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    122422203 (PPP3CA)
   04660 T cell receptor signaling pathway
    122422203 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    122422203 (PPP3CA)
   04659 Th17 cell differentiation
    122422203 (PPP3CA)
   04662 B cell receptor signaling pathway
    122422203 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    122422203 (PPP3CA)
   04921 Oxytocin signaling pathway
    122422203 (PPP3CA)
   04924 Renin secretion
    122422203 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    122422203 (PPP3CA)
   04728 Dopaminergic synapse
    122422203 (PPP3CA)
   04720 Long-term potentiation
    122422203 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    122422203 (PPP3CA)
   04380 Osteoclast differentiation
    122422203 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122422203 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122422203 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    122422203 (PPP3CA)
   05163 Human cytomegalovirus infection
    122422203 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122422203 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122422203 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122422203 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    122422203 (PPP3CA)
   05020 Prion disease
    122422203 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    122422203 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    122422203 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122422203 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ccad01009]
    122422203 (PPP3CA)
Enzymes [BR:ccad01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     122422203 (PPP3CA)
Protein phosphatases and associated proteins [BR:ccad01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     122422203 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 122422203
NCBI-ProteinID: XP_043294457
LinkDB
Position
19:complement(40080591..40392681)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEETV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacggcaaaagaagtgtttgataacgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggcttgaagagaccgtt
gcattgagaataataacagagggggcttccattcttcgacaggaaaaaaacttgctggat
attgatgctccagtcacagtttgtggggacatccatggacaattctttgacttgatgaaa
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgcatggat
gcctttgattgcctgcccctggctgccctgatgaaccagcagttcctgtgtgtacatggc
ggtttgtctccagagataaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagacccgctggaggattttgga
aacgagaagactcaggaacatttcactcacaacacagtcaggggatgttcatacttctac
agttacccggctgtgtgtgaattcttgcagcacaataacttgttatctatcctccgagct
catgaagcccaagatgcagggtaccgcatgtataggaaaagccaaacaacaggcttccct
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tattggcttccaaatttcatggatgttttcacctggtccctgccttttgttggggaaaaa
gtgactgagatgctggtaaacgtcctcaacatctgctcagacgatgaactaggatcagaa
gaagatggatttgatggagcaacagctgcagccaggaaggaggtgataagaaacaagatc
cgagccatcggcaagatggccagagtgttctcggttctcagagaagagagcgagagtgtg
ctgacgctgaaaggcctgacgcccacaggcatgctccccagcggcgtgctttctggaggg
aaacaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccacctcgcagagatgccatgccctccgacgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatc
cagtga

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