KEGG   Cervus canadensis (wapiti): 122423293
Entry
122423293         CDS       T07554                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad01521  EGFR tyrosine kinase inhibitor resistance
ccad01522  Endocrine resistance
ccad04010  MAPK signaling pathway
ccad04014  Ras signaling pathway
ccad04015  Rap1 signaling pathway
ccad04066  HIF-1 signaling pathway
ccad04068  FoxO signaling pathway
ccad04081  Hormone signaling
ccad04114  Oocyte meiosis
ccad04115  p53 signaling pathway
ccad04150  mTOR signaling pathway
ccad04151  PI3K-Akt signaling pathway
ccad04152  AMPK signaling pathway
ccad04211  Longevity regulating pathway
ccad04213  Longevity regulating pathway - multiple species
ccad04510  Focal adhesion
ccad04550  Signaling pathways regulating pluripotency of stem cells
ccad04730  Long-term depression
ccad04750  Inflammatory mediator regulation of TRP channels
ccad04913  Ovarian steroidogenesis
ccad04914  Progesterone-mediated oocyte maturation
ccad04935  Growth hormone synthesis, secretion and action
ccad04960  Aldosterone-regulated sodium reabsorption
ccad05200  Pathways in cancer
ccad05202  Transcriptional misregulation in cancer
ccad05205  Proteoglycans in cancer
ccad05214  Glioma
ccad05215  Prostate cancer
ccad05218  Melanoma
ccad05224  Breast cancer
ccad05410  Hypertrophic cardiomyopathy
ccad05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122423293 (IGF1)
   04014 Ras signaling pathway
    122423293 (IGF1)
   04015 Rap1 signaling pathway
    122423293 (IGF1)
   04066 HIF-1 signaling pathway
    122423293 (IGF1)
   04068 FoxO signaling pathway
    122423293 (IGF1)
   04151 PI3K-Akt signaling pathway
    122423293 (IGF1)
   04152 AMPK signaling pathway
    122423293 (IGF1)
   04150 mTOR signaling pathway
    122423293 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    122423293 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    122423293 (IGF1)
   04115 p53 signaling pathway
    122423293 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122423293 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    122423293 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    122423293 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    122423293 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    122423293 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    122423293 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    122423293 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122423293 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    122423293 (IGF1)
   04213 Longevity regulating pathway - multiple species
    122423293 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122423293 (IGF1)
   05202 Transcriptional misregulation in cancer
    122423293 (IGF1)
   05205 Proteoglycans in cancer
    122423293 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    122423293 (IGF1)
   05218 Melanoma
    122423293 (IGF1)
   05215 Prostate cancer
    122423293 (IGF1)
   05224 Breast cancer
    122423293 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    122423293 (IGF1)
   05414 Dilated cardiomyopathy
    122423293 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122423293 (IGF1)
   01522 Endocrine resistance
    122423293 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ccad04052]
    122423293 (IGF1)
Cytokines and neuropeptides [BR:ccad04052]
 Cytokines
  Growth factors (RTK binding)
   122423293 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 122423293
NCBI-ProteinID: XP_043296124
LinkDB
Position
21:complement(50087996..50167790)
AA seq 188 aa
MGKISSLPTQLFKCCFCDFLKQVKMPVTSSSHLFYLALCLLAFTSSATAGPETLCGAELV
DALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKAAR
SVRAQRHTDMPKAQKYQPPSTNKKMKSQRRRKGGPKKHPGGEQKEGTEGSQQMKGKMKEQ
RRETGARN
NT seq 567 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aagcaggtgaagatgcccgtcacatcctcctcgcatctcttctacctggccctgtgcttg
ctcgccttcaccagctctgccacggcgggacccgagaccctctgcggggctgagttggtg
gatgctctccagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtac
ggctcgagcagtcggagggcgccccagacgggaatagtggatgagtgctgcttccggagc
tgtgatctgaggaggctggagatgtactgcgcgcctctcaagcccaccaaggcggcccgc
tcagtccgtgcccagcgccacaccgacatgcccaaggctcagaagtatcagcccccatct
accaacaagaaaatgaagtctcagaggagaaggaaaggtgggccaaagaaacacccagga
ggggaacagaaggaggggacggaaggaagtcagcagatgaaagggaagatgaaagagcag
aggagagagactggagctaggaactga

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