Cervus canadensis (wapiti): 122424243 Help Entry 122424243         CDS       T07554                                  Symbol EGFR Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism ccad  Cervus canadensis (wapiti) Pathway ccad01521   EGFR tyrosine kinase inhibitor resistance ccad01522   Endocrine resistance ccad03272   Virion - Hepatitis viruses ccad04010   MAPK signaling pathway ccad04012   ErbB signaling pathway ccad04014   Ras signaling pathway ccad04015   Rap1 signaling pathway ccad04020   Calcium signaling pathway ccad04066   HIF-1 signaling pathway ccad04068   FoxO signaling pathway ccad04072   Phospholipase D signaling pathway ccad04144   Endocytosis ccad04151   PI3K-Akt signaling pathway ccad04510   Focal adhesion ccad04520   Adherens junction ccad04540   Gap junction ccad04630   JAK-STAT signaling pathway ccad04810   Regulation of actin cytoskeleton ccad04912   GnRH signaling pathway ccad04915   Estrogen signaling pathway ccad04921   Oxytocin signaling pathway ccad04926   Relaxin signaling pathway ccad04928   Parathyroid hormone synthesis, secretion and action ccad04934   Cushing syndrome ccad05160   Hepatitis C ccad05163   Human cytomegalovirus infection ccad05165   Human papillomavirus infection ccad05171   Coronavirus disease - COVID-19 ccad05200   Pathways in cancer ccad05205   Proteoglycans in cancer ccad05206   MicroRNAs in cancer ccad05207   Chemical carcinogenesis - receptor activation ccad05208   Chemical carcinogenesis - reactive oxygen species ccad05210   Colorectal cancer ccad05212   Pancreatic cancer ccad05213   Endometrial cancer ccad05214   Glioma ccad05215   Prostate cancer ccad05218   Melanoma ccad05219   Bladder cancer ccad05223   Non-small cell lung cancer ccad05224   Breast cancer ccad05225   Hepatocellular carcinoma ccad05226   Gastric cancer ccad05230   Central carbon metabolism in cancer ccad05231   Choline metabolism in cancer ccad05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:ccad00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03272 Virion - Hepatitis viruses     122424243 (EGFR)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     122424243 (EGFR)    04012 ErbB signaling pathway     122424243 (EGFR)    04014 Ras signaling pathway     122424243 (EGFR)    04015 Rap1 signaling pathway     122424243 (EGFR)    04630 JAK-STAT signaling pathway     122424243 (EGFR)    04066 HIF-1 signaling pathway     122424243 (EGFR)    04068 FoxO signaling pathway     122424243 (EGFR)    04020 Calcium signaling pathway     122424243 (EGFR)    04072 Phospholipase D signaling pathway     122424243 (EGFR)    04151 PI3K-Akt signaling pathway     122424243 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     122424243 (EGFR)   09144 Cellular community - eukaryotes    04510 Focal adhesion     122424243 (EGFR)    04520 Adherens junction     122424243 (EGFR)    04540 Gap junction     122424243 (EGFR)   09142 Cell motility    04810 Regulation of actin cytoskeleton     122424243 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     122424243 (EGFR)    04915 Estrogen signaling pathway     122424243 (EGFR)    04921 Oxytocin signaling pathway     122424243 (EGFR)    04926 Relaxin signaling pathway     122424243 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     122424243 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122424243 (EGFR)    05206 MicroRNAs in cancer     122424243 (EGFR)    05205 Proteoglycans in cancer     122424243 (EGFR)    05207 Chemical carcinogenesis - receptor activation     122424243 (EGFR)    05208 Chemical carcinogenesis - reactive oxygen species     122424243 (EGFR)    05230 Central carbon metabolism in cancer     122424243 (EGFR)    05231 Choline metabolism in cancer     122424243 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     122424243 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     122424243 (EGFR)    05212 Pancreatic cancer     122424243 (EGFR)    05225 Hepatocellular carcinoma     122424243 (EGFR)    05226 Gastric cancer     122424243 (EGFR)    05214 Glioma     122424243 (EGFR)    05218 Melanoma     122424243 (EGFR)    05219 Bladder cancer     122424243 (EGFR)    05215 Prostate cancer     122424243 (EGFR)    05213 Endometrial cancer     122424243 (EGFR)    05224 Breast cancer     122424243 (EGFR)    05223 Non-small cell lung cancer     122424243 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     122424243 (EGFR)    05171 Coronavirus disease - COVID-19     122424243 (EGFR)    05163 Human cytomegalovirus infection     122424243 (EGFR)    05165 Human papillomavirus infection     122424243 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122424243 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     122424243 (EGFR)    01522 Endocrine resistance     122424243 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccad01001]     122424243 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ccad04147]     122424243 (EGFR) Enzymes [BR:ccad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      122424243 (EGFR) Protein kinases [BR:ccad01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    122424243 (EGFR) Exosome [BR:ccad04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    122424243 (EGFR)   Exosomal proteins of pancreatic cancer cells    122424243 (EGFR)   Exosomal proteins of bladder cancer cells    122424243 (EGFR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like ABC1 Borrelia_P83 Haspin_kinase Motif Other DBs NCBI-GeneID:  122424243 NCBI-ProteinID:  XP_043297740 LinkDB All DBs Position 22:complement(58156616..58381959) Genome browser AA seq 1208 aa AA seqDB search MRLSGAGRAALLVLLAAHFQASLALEEKKVCQGTSNKLTLLGTFEDHFLSLQRMFNNCEV VLGNLEITYMQSSYNLSFLKTIQEVAGYVLIALNTVEKIPLENLQIIRGNVLYESTHALA VLSNYGANRTGLRELPLRNLQEILQGAVRFSNNPVLCNVDTIQWRDIVNPEFLSNMTGDF QNQLSNCPKCDPVCLNGSCWGAGKENCQKLTKIICAQQCSGRCRGRSPSDCCHNQCAAGC TGPRESDCLVCRRFRDEATCKDTCPPLMLYDPTTYEMKVNPLGKYSFGATCVKKCPRNYV VTDHGSCVRACSSDSQEVEEDGVRKCKKCDGPCGKVCNGIGIGEFKGTLSINATNIKHYR NCTSISGDLHILPVAFKGDSFTHTAPLDPKELDILKTVKEITGFLLIQAWPENRTDLDAF ENLEIIRGRTKQHGQFSLAVVGLSITSLGLRSLKEISDGDVIISGNQNLCYADTIRWKKL LGTSTQNAKISKNRSQQECSATGHICHPLCSSEGCWGPGPKYCLSCQNFSRGKECVEKCN ILEGEPREFVENSECVQCHPECLPQAMNVTCTGRGPGNCVKCAHYIDGPHCVKTCPAGVA GENGTLIWKFADASHVCHLCHPNCTYGCTGPGLKGCAADGPKIPSIATGIVGGLLLALLL ALSVGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY GVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK FRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDAEEYLIPQ QGFFHSPATSRTPLLSSLSASSNTPTVTCVDRNGSYPLKEDSFLQRYSSDPTGALTEDSM DDAFLPAPEYVNQSVPKRPAGSVQNPVYHNQPLYPAPGRDPQYQNSRSHAVDNPEYLNTT HPACVNGVLDGPALWAQKGSYQISLDNPDYQQAFFPKEAKSNGIFKGPAAENAEYLRAAP AGSDFTGA NT seq 3627 nt NT seq  +upstreamnt  +downstreamnt atgcgactctccggggcgggccgcgcggcgctcctggtgctgctggccgcgcacttccag gcgagtctagcgctggaggagaagaaagtttgccaagggacaagtaacaagctcaccctg ttgggcacttttgaagaccactttctgagcctccagaggatgttcaacaactgtgaggtg gtccttgggaatttggaaattacctacatgcagagtagttacaacctttcttttctcaag accatccaggaggttgctggctatgtgctcattgccctcaacacggtggagaagattccg ctggaaaacctgcagatcatccgaggaaatgtgctttatgaaagcacccatgccttagcg gtcttatccaactatggagcaaacagaaccggactgagggagctgcccttgagaaactta caggaaattctgcaaggtgccgtgcgattcagcaacaaccctgtcctctgcaacgtggac accatccagtggcgggacatcgtcaaccctgaatttctaagcaacatgacaggggacttt cagaaccagctgagcaactgcccgaagtgtgatccagtctgtctcaatggaagctgctgg ggtgctgggaaggagaactgccagaaattgaccaaaatcatctgtgcccagcagtgttcc gggcgctgccgtggcaggtcccccagcgactgctgtcataaccagtgtgccgctggctgc acggggcctcgggagagtgactgcctggtctgccgcaggttccgtgatgaagccacctgc aaggacacgtgtccaccactcatgctctatgaccctaccacctacgagatgaaggtcaac ccgctggggaagtacagctttggcgccacctgtgtcaagaagtgtccccgtaactatgtg gtgaccgaccacggctcatgcgtccgcgcctgcagctctgacagccaggaggtagaagaa gatggtgtccgcaagtgtaaaaagtgtgacgggccttgtggcaaagtttgtaacggaata ggaatcggtgagtttaaaggcacactttccataaatgctacaaacattaaacactacaga aactgcacatccatcagtggagatcttcatatcctgccagtagcatttaagggtgactcc ttcacacatactgctcctctggacccgaaagagctggacattctcaaaactgtaaaagaa attacagggtttttgctgattcaggcctggcccgaaaacaggactgacctcgatgctttt gagaacctggaaatcatacgtggcagaacgaagcagcatggccagttctctcttgcggtc gtcggcctgagtataacatccttggggttacgctccctcaaggagataagcgatggcgat gtgataatttcaggaaatcaaaacctgtgctatgcggacacgatacgctggaagaagctt ttggggacctcaactcagaatgccaaaatttcaaaaaacaggagtcaacaagagtgcagc gccacgggccacatctgtcaccctctgtgctcatcagagggctgctggggacctggaccc aaatactgcttgtcctgtcagaacttcagtcgtggcaaggagtgtgtggaaaagtgcaac attctagagggagagcccagggagttcgtggagaattccgagtgcgtgcagtgccatcca gaatgcctgccccaggccatgaatgtgacctgcactggacgcggaccaggcaactgtgtg aaatgtgcccactacattgacggccctcactgcgtcaagacctgccctgctggagtcgcg ggagagaacggcaccctgatctggaaatttgcagatgccagtcatgtgtgtcacctctgc caccccaactgcacctatggctgtacagggccaggtctcaaaggctgtgcagcagatggg cccaagatcccgtccatcgccacgggcatcgtgggcggcctgctgctggcgctgctgctg gccctgagcgtcggcctcttcatgcgcaggcgccacatcgtgcgcaagcgcactctgcgc cggctgctgcaggagcgagagctcgtggagcctctgacgcccagcggagaagctcccaac caagctctcttgaggatcttaaaggaaacagaattcaaaaagatcaaggtgttgggctca ggagcattcggcaccgtgtacaagggactctggatcccagaaggcgagaaggttaaaatt cctgtagctatcaaggagttaagagaagccacatctccaaaagccaacaaggaaattctc gatgaggcctatgtgatggccagcgtggacaacccccacgtgtgccgcctgctgggcatc tgcctgacctccacagtgcagctcatcacacagctcatgcccttcggctgcctgctcgac tacgtccgcgagcacaaggacaacatcggctcccagtacctgctcaactggtgtgtgcag atcgcaaagggcatgaattacctggaagaccggcgcttggtgcacagggacctggcggcc aggaacgtgctggtgaagacgccgcagcacgtgaagatcacagactttgggctggccaag ctgctgggtgccgaggagaaggagtatcacgcagaaggaggcaaggtccctatcaaatgg atggctttggaatcaattttacaccgaatttatacccatcagagtgatgtctggagctat ggagtcactgtttgggagttgatgacctttggatccaagccgtacgatggaatccctgcg agtgagatctcaactgtcctggagaaaggagagcgcctcccgcagccacccatctgcacc atcgacgtctacatgatcatggtcaagtgctggatgatagatgcagacagtcgcccaaag ttccgtgagttgatccttgaattctccaagatggcccgagacccccagcgctaccttgtc atccagggggatgagagaatgcatttgccaagccctacagactccaacttttaccgcgcc ctgatggatgaggaggacatggaggacgttgtggatgctgaggagtacctcatcccccag cagggcttcttccacagccccgccacctcccggacgcccctcctcagctctctgagcgcc tccagcaacactcccactgtgacttgcgttgatagaaacgggagctaccctctcaaggaa gatagcttcctgcagcgctacagctccgaccccactggtgccctcaccgaggacagcatg gacgacgccttcctcccagcccccgaatatgtaaaccagtctgttcccaaaagacccgca ggctctgtccagaaccctgtctatcacaatcagcctctatatccagcccctggcagagac cctcagtaccaaaattcacgcagccacgccgtggacaaccctgagtatctcaacaccacc catccagcctgtgtcaatggtgtactcgacggccctgccctctgggctcagaagggcagt taccaaattagcctagacaaccctgactaccagcaggccttctttcccaaggaagccaag tcgaatggcatctttaaggggcctgcagctgaaaatgcagaatacctgcgggcagcacca gcaggcagtgactttactggggcctga

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