Cervus canadensis (wapiti): 122426429
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Entry
122426429 CDS
T07554
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00230
Purine metabolism
ccad00670
One carbon pool by folate
ccad01100
Metabolic pathways
ccad01523
Antifolate resistance
Module
ccad_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122426429 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122426429 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122426429 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ccad04147
]
122426429 (ATIC)
Enzymes [BR:
ccad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
122426429 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
122426429 (ATIC)
Exosome [BR:
ccad04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
122426429 (ATIC)
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GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
122426429
NCBI-ProteinID:
XP_043301296
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Position
24:complement(31245517..31267855)
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AA seq
592 aa
AA seq
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MAPGQLALFSVSDKTGLVEFARNLASVGLNLIASGGTAKALRDAGLAVRDVSEITGFPEM
LGGRVKTLHPAVHAGILARNIPEDSADMAKLDFDLIRVVVCNLYPFVKTVASPGVTVEEA
VEHIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVASEMQDSDSKDTSLETRRLLALKAFT
HTAQYDEAISDYFRKEYSKGVSQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGLPAAASFKHVSPAGAAVGIPLSEDEASVCMVNDLYKTLTPIA
TAYARARGADRMSSFGDFVALSDICDVPTAKIISREVSDGIIAPGYENEALKILSKKKNG
NYCVLQMDQSYSPDENEVRTLFGLRLSQKRNNSVVNRSLFSNIVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEGEDLIKWKALFEEVPELLTETEKKEWVDKLNEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgctttatttagtgtctctgacaaaactggccttgtggagttt
gccaggaacttagcttctgttggtttgaatctgatcgcctctggagggactgcaaaagcc
ctcagagatgctggtttggcagtcagagatgtctctgagataactggatttcctgaaatg
ctaggggggcgtgtaaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagatagtgctgacatggccaaacttgatttcgatcttataagagttgttgtt
tgtaatctgtatccctttgtgaagacagtggcttctccaggtgtaactgttgaagaggct
gttgaacatattgacattggaggggtgactctgctgagagcagcagccaaaaaccacgct
cgggtgacggtagtatgtgagccggaggactatgcagccgtagcctcagagatgcaggac
tccgacagcaaagacacatccttggagacaagacgcctgttagccttgaaggcttttact
catacagcacagtatgatgaagcaatttcagattacttcaggaaagagtacagtaaagga
gtatctcagatgcccctgaggtatggcatgaaccctcatcagactcctgcccagctgtat
accctgaagcccaagctccctatcacagttctgaatggagcccctggatttataaacttg
tgtgatgctttgaacgcctggcagctggtgaaggagctcaaagaagctttaggccttcca
gccgctgcttctttcaaacatgttagcccagcaggtgctgctgttggaattccacttagt
gaagacgaagccagcgtctgtatggtcaatgatctgtacaaaaccctcacacctatagcc
actgcatatgcaagagcaagaggggctgataggatgtcttcctttggtgactttgttgca
ttatctgatatttgcgatgtccctactgccaaaattatctccagagaggtatctgatggt
attattgccccgggatatgaaaatgaagctttgaaaatactttccaaaaagaaaaatggg
aattactgtgttcttcagatggaccagtcttacagtccagatgaaaatgaagttcgaact
ctttttggtcttcgtttaagccagaagagaaataatagtgttgtcaacaggtcactgttt
agcaacattgttaccaagaataaagatttgccggaatctgcgctcagggacctcattgtg
gccaccattgctgtcaagtacactcagtctaactctgtgtgctatgccaagaacgggcag
gttattggcatcggagcaggacagcagtctcgtatacactgcacacgccttgcaggtgac
aaggcaaactattggtggcttagacatcacccgcaagtgctttccatgaagtttaaaact
ggcgtgaagagagcagaaatctccaatgccatcgatcagtatgttactggaactatcggc
gagggtgaagatttgattaagtggaaggcactgtttgaggaggtccctgagttgttaacc
gagacagaaaaaaaggaatgggttgacaaacttaatgaagtttccatcagctctgatgct
ttctttcctttccgggacaatgtagacagagctaaaaggagtggtgtggcctacatcgct
gccccttccggttctgccgctgacaaagttgtgatcgaggcttgcgatgagctgggaata
atccttgctcacacgaatctccggctcttccatcactga
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