Cervus canadensis (wapiti): 122427446
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Entry
122427446 CDS
T07554
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00260
Glycine, serine and threonine metabolism
ccad00630
Glyoxylate and dicarboxylate metabolism
ccad00670
One carbon pool by folate
ccad01100
Metabolic pathways
ccad01200
Carbon metabolism
ccad01230
Biosynthesis of amino acids
ccad01240
Biosynthesis of cofactors
ccad01523
Antifolate resistance
ccad04981
Folate transport and metabolism
Module
ccad_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
122427446 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
122427446 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122427446 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
122427446 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122427446 (SHMT2)
Enzymes [BR:
ccad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
122427446 (SHMT2)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
122427446
NCBI-ProteinID:
XP_043302884
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All DBs
Position
25:1732414..1737641
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AA seq
504 aa
AA seq
DB search
MLSFSFIWATRPLRRCGQLVGMAVRCQHSEAAQTQTGEASKGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRLMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPQTGLIDYEQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARAGLIFYRKGVWAVD
PKSGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALQQACTPMFREYSLQILKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRGFREDDFRKVVGFIDEGVNIGLEVKSKTTKLQDFKSFLLKDPETSH
QLADLRQRVEQFARAFPMPGFDDH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccttctcttttatttgggcgactcggcctctgcggagatgtggtcagctggtt
gggatggccgtgcggtgccaacacagtgaggcggcccagactcagactggagaagcaagc
aagggctggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctg
cggagagagaaggacaggcagtgtcgtggcctggagctcattgcttcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagaggtactatggaggagccgaggtggtggatgagatcgagctgctgtgtcag
cgccgggccctggaggcctttgacctggatccggctcagtggggagtcaatgtccagccc
tactccgggtccccagccaacctggctgcctacacagcccttctgcagcctcacgaccga
ctcatggggctggacttgcccgatgggggccatctcacccacggctacatgtctgatgtc
aagcgagtctcggctacatccatcttcttcgagtctatgccttataagctgaacccccag
accggcctcattgactatgagcagctggccctcactgctcggctcttcaggccacgactc
atcatagctggtaccagtgcctatgcgcgcctcattgactacgcccgcatgagagaagtg
tgtgacgaggtcaaggcacacctcttggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacccttcaagcacgcggatgttgtcaccacgaccactcacaag
acccttcgaggggccagggcaggactcatcttctaccggaagggggtgtgggctgtggac
cccaaaagtggccgagagatcccttacacattcgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccacgccatcgctgcagtggctgtggccctacag
caggcctgcacccccatgttccgggagtactccctgcagattctgaagaacgctcgggcc
atggctgatgccctgctggagcggggctactccctagtgtctggcggcactgacaaccac
ctagtgctggtagacctgcggccaaagggcctggacggagctcgagccgaacgggtgttg
gaacttgtatccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcacc
cctgggggcctgcggctgggggccccagccctgacttctcgagggttccgtgaagatgac
ttccggaaagttgtaggctttatagatgaaggtgtcaacattggcttggaagtgaagagc
aagaccaccaaactccaggatttcaaatctttcctgctcaaagacccagagacaagtcat
cagctggccgaccttaggcaacgcgtggagcagttcgccagggccttccccatgcctggc
tttgatgatcactga
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