Cervus canadensis (wapiti): 122427991
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Entry
122427991 CDS
T07554
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad01521
EGFR tyrosine kinase inhibitor resistance
ccad04010
MAPK signaling pathway
ccad04014
Ras signaling pathway
ccad04015
Rap1 signaling pathway
ccad04020
Calcium signaling pathway
ccad04072
Phospholipase D signaling pathway
ccad04144
Endocytosis
ccad04151
PI3K-Akt signaling pathway
ccad04510
Focal adhesion
ccad04540
Gap junction
ccad04630
JAK-STAT signaling pathway
ccad04810
Regulation of actin cytoskeleton
ccad05163
Human cytomegalovirus infection
ccad05200
Pathways in cancer
ccad05206
MicroRNAs in cancer
ccad05214
Glioma
ccad05215
Prostate cancer
ccad05218
Melanoma
ccad05230
Central carbon metabolism in cancer
ccad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122427991 (PDGFRA)
04014 Ras signaling pathway
122427991 (PDGFRA)
04015 Rap1 signaling pathway
122427991 (PDGFRA)
04630 JAK-STAT signaling pathway
122427991 (PDGFRA)
04020 Calcium signaling pathway
122427991 (PDGFRA)
04072 Phospholipase D signaling pathway
122427991 (PDGFRA)
04151 PI3K-Akt signaling pathway
122427991 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122427991 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122427991 (PDGFRA)
04540 Gap junction
122427991 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122427991 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122427991 (PDGFRA)
05206 MicroRNAs in cancer
122427991 (PDGFRA)
05230 Central carbon metabolism in cancer
122427991 (PDGFRA)
05231 Choline metabolism in cancer
122427991 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
122427991 (PDGFRA)
05218 Melanoma
122427991 (PDGFRA)
05215 Prostate cancer
122427991 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
122427991 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122427991 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccad01001
]
122427991 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ccad04090
]
122427991 (PDGFRA)
Enzymes [BR:
ccad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122427991 (PDGFRA)
Protein kinases [BR:
ccad01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
122427991 (PDGFRA)
CD molecules [BR:
ccad04090
]
Proteins
122427991 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR-1-like_Ig-like
VEGFR1-3_N_Ig-like
V-set
Herpes_gE
Kinase-like
Motif
Other DBs
NCBI-GeneID:
122427991
NCBI-ProteinID:
XP_043303516
LinkDB
All DBs
Position
26:3000803..3049560
Genome browser
AA seq
1129 aa
AA seq
DB search
MMSSEEHWAMQLLVPSTQNGSQVLRHPLAVQASFPKFSRTMGTSHWALLALGCLFTGPSL
ILCQLSLPSILPNENERVVPLNSSFSLRCFGESEVSWQYPMSEEEYPDVEIRNEENNSGL
FVTVLEVVSASAAHTGPYTCYYNHTQVDENEVEGRHIYIYVPDPDVAFVPLGMTDSLVIV
EDEDSVIIPCRTTDPETPVTLLSSEGVVHASYDSRQGFKGTFAVGLYICEATVRGKKFQT
IPFNVYAYTATSKLDLEMESPKTVYKAGESIVITCTVFNNEVVDFQWTYPGQMKGKGITR
LEETKFPAIKLVYTLRVPEATVKDSGDYECAAHQATKEVKKMRNVTISVHEKGFIEIKPN
FNLLEAVNLHEVKHFVVDVQAYPPPKITWLKDNLTLIENLTEITTDIEKIQEISYRSKLK
LIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDLVDDHHGSNGGQTVRCTAEGT
PLPDIEWMVCKDIKKCNNETSWTVLANNISNIITEVHPRDRSTVEGQVTFAKVEETIAVR
CLARNLLGLESRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWR
VIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQP
VMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYG
DLVNYLHKNRDSFLNHHPEKPKKELDIFGLNPADENTRSYVILSFENNGDYMDMKQADTT
QYVPMLERKEVSKYSDIQRALYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTY
QVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVK
WMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDH
ATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARM
RVDSDNAYIGVTYKNEDDKLKDWEGGLDEQRLSADSGYIIPLPDIDPAPEEEDLGKRNRH
SSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL
NT seq
3390 nt
NT seq
+upstream
nt +downstream
nt
atgatgtcctctgaggaacactgggcgatgcagcttctggtaccctctacccagaatggc
tctcaagtattaagacatccgttggcagtccaagcatcttttccaaagttttccagaact
atggggacttcccattgggcactcctggccttaggctgtctcttcacagggccgagccta
atcctctgccagctttcattaccctccatcctgcccaatgaaaatgagagggttgtgccg
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagtaccccgatgtggaaatcagaaacgaggagaacaacagtggcctt
tttgtgacggtactggaagtggtcagcgcctcggcggcccacactgggccgtacacttgc
tattacaaccacacgcaggtggatgagaacgaggtcgagggcagacacatttacatctac
gtgccagacccagatgtagccttcgtacctctaggaatgacagattccttggtcatcgtg
gaggacgaagattccgtcatcatcccatgccgcacgactgatcctgagactccggtgacc
ttactcagcagtgagggggtagtgcatgcctcctatgacagcagacaaggctttaaagga
acctttgctgtcgggctctatatctgtgaggccacggtcagagggaagaagttccagacc
attccattcaatgtttatgcttacacagcaacatcaaaacttgatctggaaatggaatct
cctaagactgtatataaggcaggcgaatcgattgtgatcacctgcactgtctttaacaac
gaggtggttgactttcagtggacttaccctggacaaatgaaaggcaaaggcatcacgagg
ctggaggaaaccaagttcccggccatcaagctggtgtacactctgagggttcctgaggcc
acagtgaaagacagtggagattacgagtgtgctgcccaccaggccaccaaggaggtcaaa
aagatgaggaacgtcaccatttctgttcacgagaaaggatttattgaaatcaaacccaac
tttaacctgttggaagctgtcaacctgcatgaagtcaagcattttgtggtggatgtgcag
gcctatccccctcccaagataacctggctgaaggacaacctgactctgattgagaatctc
acggagatcaccactgacatagaaaagattcaggaaataagttatcgaagcaaattaaag
ctgatccgagcaaaggaagaagacagtggccattatactattgtagttcaaaatgaagat
gatgtgaagagctatacttttgaactcttgactcaagttccatcctccatactggacttg
gttgacgatcaccatggctctaacgggggccagactgtgagatgcacggccgaagggacc
cctcttcctgatatcgagtggatggtttgcaaggatattaagaaatgtaacaatgaaact
tcatggacagttttggccaacaacatttcaaacatcatcacagaggttcacccccgagac
aggagcacggtggaaggccaggtgacgttcgccaaagtggaggagaccattgcagtccgg
tgcctggccaggaacctcctcgggctggaaagccgagaactgaagctggtggctcccact
ctgcgctctgaactcactgtagcggctgcagtcctggtgctgttggtgattgtgatcatc
tcactcattgtcctggtcgtcatttggaaacagaaaccaaggtatgaaatccgttggagg
gtcattgaatcaatcagccccgatggacatgagtacatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggactcgtgcttggtcggatcctgggg
tctggtgcatttgggaaagtggttgaaggaactgcctatggattaagtcggtctcaacct
gtcatgaaagtagcagtgaagatgctaaaacccacagccagatccagtgaaaaacaagct
ctcatgtctgaactgaagattatgacccacctggggccgcatttaaacatcgtgaacttg
ctgggcgcctgcaccaagtcaggccccatttacatcatcactgagtactgcttctatggg
gatttggtcaactatttacataagaatagggacagcttcctgaaccaccatccagagaag
ccaaagaaagagctggacatttttggattgaacccggctgacgaaaacacaagaagttac
gttatcttatcttttgaaaacaatggtgactatatggacatgaagcaagctgacaccaca
cagtatgtccccatgctggaaaggaaagaggtttctaaatactcagacatccagagagcg
ctgtatgatcgcccagcctcgtataagaagaaatccatgttagactcagaagtcaaaaac
ctcctttcagatgataactcagaaggcctgactttgttggatttgttgagctttacctac
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccaccgggacctggcg
gctcgcaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgactttggcctggcc
agagacatcatgcatgattcgaactacgtgtccaaaggcagtacctttctccccgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacgctgagtgacgtctggtcc
tatggcatcctgctctgggagatcttttcccttggtggtacaccctaccctggcatgatg
gtggattctacattctacaataagatcaagagtggataccggatggccaagcctgaccat
gccaccagtgaagtgtacgagatcatggtgaagtgctggaacagtgagccggagaagaga
ccctccttttaccacctgagtgaaattgtggagaatctgctgcctggacaatataaaaag
agttatgaaaagatccacctggactttctgaagagcgaccatcccgctgtggcgcgcatg
cgcgtggactccgacaacgcctacatcggcgtcacctacaaaaatgaggacgataagctg
aaggactgggagggtggcctcgacgagcagaggctgagtgcagacagcggctacatcatc
cctctgcccgacatcgaccctgctcctgaggaggaagacctgggcaagcggaacagacac
agctcacagacctctgaagagagtgccattgagacaggttccagcagttctaccttcatc
aagagagaggacgagaccatcgaggacatcgacatgatggatgacattggcatagactcc
tcggatctggtggaggacagcttcctgtaa
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