Cervus canadensis (wapiti): 122428721
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Entry
122428721 CDS
T07554
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00230
Purine metabolism
ccad00670
One carbon pool by folate
ccad01100
Metabolic pathways
ccad01523
Antifolate resistance
Module
ccad_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122428721 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122428721 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122428721 (GART)
Enzymes [BR:
ccad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
122428721 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
122428721 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
122428721 (GART)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_4
RimK
Amidase_2
DUF6365
Motif
Other DBs
NCBI-GeneID:
122428721
NCBI-ProteinID:
XP_043304713
LinkDB
All DBs
Position
27:1247619..1275528
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLNSVGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFIKPEEACDFIMSADFPALVVKASGLAAGKGVIVAKNKEEACEAVREIMQGKAF
GEAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQKEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYSKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRGNLTSALEEARKGLAAIKFEGAVYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFTDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLRMTEAVIAGIAQACRKAGCALLGGETAEMPDMYAPGEYDLAGFAIGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGNQTLGDLLLTPTR
IYSHSLLPVLRSGRVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQQEG
HLSEEEMAKTFNCGIGAALVVSEDLVKQTLQDIEQHQEEAWVIGRVVACPEGSPRVKVEH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSLAHIVVV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKNREAFDTAVDEVLEEFSTDIVCLAGFMRILS
GSFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVESLSERVKLAEHKIFPSALQLVASGAVRLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcagtggaggacgggaacacacgctggcctggaaa
cttgcacagtctactcatgtcaaacaagtgttggttaccccaggaaatgcaggcactgcc
tgctctgagaagatttcaaatactgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctagctgct
ggaattgttgggaacctgaactctgtgggagttcggtgctttggccccacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacacggaatccca
actgcaagatggagagctttcattaaacctgaagaagcctgtgacttcattatgagtgca
gacttccccgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtaattgtt
gccaagaacaaagaggaggcctgtgaagctgtcagggagattatgcagggtaaagctttt
ggagaagcaggagaaacagttgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggacggactgtggcccccatgccaccagcacaggaccataagcga
ctgctggagggcgatcagggccccaacactgggggaatgggcgcctactgtccagcccct
caggtttctaaggatttgttgctaaaaattaaaaataccattcttcagaggacagtggat
ggcatgcagaaggagggtatgccgtacacaggtgtcctctatgctggtataatgttgacc
aagaacggccccaaagttctggagtttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgatccagtctaccttagatggcctg
ctctgcacatctctgcctgtttggctggacaactgtgctgccgtaactgtggtcatggca
agtaaaggttatccaggagactacagcaagggtgtagagataacagggtttcctgaggct
caggctttaggactggaggtgttccaagcaggcactgccctaaaagatggcaaggtggtg
acgaatgggggtagggtccttactgtcacggccatcaggggaaatctcacctcagccctt
gaagaagccaggaaaggacttgccgctataaagtttgagggagctgtttataggaaagac
atcggctttcgagccatagctttcctccaacaacccaggggcctgacttacaaggaatct
ggggtagacattgcagctggtaatatgctggtccagaaaattaaacctttagcaaaggcc
acctctagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcactgatcctcttctggcctgtggaacagatggcgttgggacgaaactg
aagattgcccagcagtgcaataaacatgacaccattggtcaggatttggttgcaatgtgt
gtaaatgacattcttgcacaaggagcagagcccctctttttccttgattacttttcctgt
ggaaaacttgacctccgtatgactgaagctgttatcgctgggatcgcccaagcttgtaga
aaggctggatgtgctctcctcggaggtgaaacggcagagatgcctgacatgtatgctcct
ggagagtatgatctagctggttttgccattggtgccatggagcgggatcaaaaacttcct
cacctggaaagaatcacggaaggggatgttgttattggaattgcttcatctggtcttcac
agcaatggattcagcctcgtgaggaaaattgtagcaaaatcttccctccagtactcttct
ccagcacctgatggctgtggtaaccagaccttaggtgacttacttctaaccccaaccaga
atctacagccactcactgttacctgtcctgcgttcaggacgtgttaaggctgttgcgcat
attactggtggaggattactggaaaacatccccagagtcctccctcagaaattgggggtg
aatttagatgcccagacctggagggtccccaggatcttctcatggttacagcaggaaggc
cacctctctgaagaggagatggccaaaacatttaactgtgggattggggctgccctcgtg
gtatcggaggacctggtgaagcagactctgcaggatattgagcagcaccaggaagaagcc
tgggtgatcggcagagtggttgcttgtcctgaaggttctcctcgtgtgaaagtcgagcat
ctgattgaaaccatgcaaataaatggatcagtattggagaatggaaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagtagctgtcttaatttctgggacaggatcaaac
ctccaagctctcatagacagcactagggaaccaagtagcttggcacacattgttgttgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccggaattcccacc
agagtaattaatcataaattatataaaaatcgtgaagcatttgacactgcagttgacgaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttgtct
ggctccttcgtcagaaaatggaatgggaaaatgctcaatatccacccatccttgctccct
tcatttaagggttcaaatgcccatgaacaagttctggacgctggggtcacaatcactggg
tgcactgtgcactttgtagctgaagatgtagatgctggtcaaattatcttacaggaagcc
gttccagtgaagaggggtgacactgttgaaagtctatctgagagagtaaaattagcggaa
cataaaatatttccctcggccctccagctggtggctagtggagctgtacggcttggagaa
aatggcaaaatctgttgggtcaaagaggaatga
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