KEGG   Cervus canadensis (wapiti): 122429019
Entry
122429019         CDS       T07554                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad04010  MAPK signaling pathway
ccad04015  Rap1 signaling pathway
ccad04218  Cellular senescence
ccad04380  Osteoclast differentiation
ccad04620  Toll-like receptor signaling pathway
ccad04664  Fc epsilon RI signaling pathway
ccad04668  TNF signaling pathway
ccad04750  Inflammatory mediator regulation of TRP channels
ccad04912  GnRH signaling pathway
ccad04935  Growth hormone synthesis, secretion and action
ccad04936  Alcoholic liver disease
ccad05014  Amyotrophic lateral sclerosis
ccad05022  Pathways of neurodegeneration - multiple diseases
ccad05132  Salmonella infection
ccad05135  Yersinia infection
ccad05145  Toxoplasmosis
ccad05161  Hepatitis B
ccad05163  Human cytomegalovirus infection
ccad05167  Kaposi sarcoma-associated herpesvirus infection
ccad05169  Epstein-Barr virus infection
ccad05170  Human immunodeficiency virus 1 infection
ccad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccad05417  Lipid and atherosclerosis
ccad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122429019 (MAP2K6)
   04015 Rap1 signaling pathway
    122429019 (MAP2K6)
   04668 TNF signaling pathway
    122429019 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    122429019 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122429019 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    122429019 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122429019 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    122429019 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122429019 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122429019 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122429019 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122429019 (MAP2K6)
   05161 Hepatitis B
    122429019 (MAP2K6)
   05163 Human cytomegalovirus infection
    122429019 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122429019 (MAP2K6)
   05169 Epstein-Barr virus infection
    122429019 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122429019 (MAP2K6)
   05135 Yersinia infection
    122429019 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122429019 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    122429019 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    122429019 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122429019 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    122429019 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    122429019 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccad01001]
    122429019 (MAP2K6)
Enzymes [BR:ccad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     122429019 (MAP2K6)
Protein kinases [BR:ccad01001]
 Serine/threonine kinases: STE group
  STE7 family
   122429019 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 122429019
NCBI-ProteinID: XP_043305130
LinkDB
Position
1:2111409..2215890
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattcccaaagaagcgttt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcccatcgtggagctgggc
cggggggcgtacggggtggtggagaagatgcggcacgtgcccagcgagcagatcatggcg
gtgaagcggatccgggccacggtcaacagccaagagcagaagcggctactgatggatctg
gatatctccatgaggaccgtggactgtcccttcacggtcaccttttacggcgcgctcttc
cgagagggggatgtctggatctgcatggagctcatggacacgtccctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagccttagaacatttacacagtaagctgtctgtcattcaccgggatgtc
aagccctccaacgtgctcatcaacgccctgggccaggtgaagatgtgcgacttcggcatc
agcggctacctggtcgactccgtggctaaaaccatcgatgccggatgcaaaccgtacatg
gcccccgagagaataaacccagagctcaaccagaagggatacagcgtgaagtccgacatc
tggagtttgggcatcaccatgatcgagctggccatcctccggtttccctacgactcgtgg
gggactcctttccagcagctcaaacaggtggtggaggagccgtcgccgcagctgcccgca
gacaagttctccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaaaggccaacatatccagagcttatgcaacatccgtttttcaccctacatgaatccaaa
gcgacagacgtggcatcttttgtaaaatcgattcttggagactaa

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