KEGG   Cervus canadensis (wapiti): 122431765
Entry
122431765         CDS       T07554                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad04064  NF-kappa B signaling pathway
ccad04072  Phospholipase D signaling pathway
ccad04151  PI3K-Akt signaling pathway
ccad04380  Osteoclast differentiation
ccad04611  Platelet activation
ccad04613  Neutrophil extracellular trap formation
ccad04625  C-type lectin receptor signaling pathway
ccad04650  Natural killer cell mediated cytotoxicity
ccad04662  B cell receptor signaling pathway
ccad04664  Fc epsilon RI signaling pathway
ccad04666  Fc gamma R-mediated phagocytosis
ccad05152  Tuberculosis
ccad05167  Kaposi sarcoma-associated herpesvirus infection
ccad05168  Herpes simplex virus 1 infection
ccad05169  Epstein-Barr virus infection
ccad05171  Coronavirus disease - COVID-19
ccad05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    122431765 (SYK)
   04072 Phospholipase D signaling pathway
    122431765 (SYK)
   04151 PI3K-Akt signaling pathway
    122431765 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122431765 (SYK)
   04613 Neutrophil extracellular trap formation
    122431765 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    122431765 (SYK)
   04662 B cell receptor signaling pathway
    122431765 (SYK)
   04664 Fc epsilon RI signaling pathway
    122431765 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    122431765 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122431765 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    122431765 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    122431765 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122431765 (SYK)
   05169 Epstein-Barr virus infection
    122431765 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122431765 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccad01001]
    122431765 (SYK)
Enzymes [BR:ccad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     122431765 (SYK)
Protein kinases [BR:ccad01001]
 Non-receptor tyrosine kinases
  SYK family
   122431765 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo DUF7063 ABC1 SH2_1 RIO1
Other DBs
NCBI-GeneID: 122431765
NCBI-ProteinID: XP_043309145
LinkDB
Position
30:complement(20014984..20119391)
AA seq 628 aa
MGDSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHDRKAHHYT
IERELNGTYAITGGRAHGSPAELCHYHSQELDGLVCLLKKPFNRPPGVQPKTGPFEDLKE
NLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLIG
SKTNGKFLIRARDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPGGKNFDTLWQLVEHYSY
KSDGLLRVLTVPCQKIGGQSGNINFRPQLPSSHPGTWSAGGIISRIKSYSFPKRDHRKAS
TSPGNQADNSATFNPYEPDRGPWANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDR
KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQL
DNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEE
CNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYY
KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYELMTL
CWTYDVENRPGFVAVELRLRNYYYDVVN
NT seq 1887 nt   +upstreamnt  +downstreamnt
atgggggacagcgccaaccacctgccattcttctttggtaacatcacgcgggaggaggcg
gaagactacctggtccaggggggcatgagcgatgggctctacctgctacgccagagccgc
aactacctgggtggctttgccctgtccgtggcacacgacaggaaggcgcatcactacacc
atcgagagggagctgaatggcacctatgccatcacgggtggccgggcccatggcagccca
gccgagctctgccactaccattcccaggagctggacggcctcgtctgcctcctcaagaag
cccttcaaccggccgccaggggtgcagcccaagacgggcccctttgaggacctaaaggag
aacctcatccgagaatacgtgaaacagacgtggaacctacagggccaagctcttgagcag
gccatcatcagccagaaacctcagctggagaaactgatcgccaccacagcccatgaaaaa
atgccctggttccatggaaaaatctctcgggatgaatctgagcagattgtcctgatagga
tcaaagacaaatggaaagtttttgatcagggccagggacaacgggtcctacgcgctgtgc
ctcctgcatgagggcaaggtgctgcactaccgcatcgacaaggacaagacggggaagctc
tccatccctggcgggaagaacttcgacacactctggcagctggtcgagcactactcttat
aaatcagatggtttgttaagagttcttacagttccatgtcaaaaaattggtgggcaatcg
ggaaatattaacttccgtccacaacttccaagttctcatcctgggacttggtcagcgggt
ggaataatctcaagaatcaaatcatactccttcccaaagcgtgaccacagaaaggcctcc
acatccccagggaaccaggcagataactctgcaacattcaacccttacgagccagaccga
gggccgtgggccaacgagagagaagctcagagagaagccttgcccatggacactgaggtc
tacgaaagcccctatgcagaccccgaggagatccggcccaaggaggtctacctggaccgg
aagctgctgaccctggaggacaaggaactgggctctgggaactttgggaccgtgaagaag
ggctattaccagatgaaaaaagttgtgaaaacagtagctgtgaaaatcctgaaaaatgag
gccaatgaccctgctcttaaggatgagttattagcagaagcaaatgtcatgcagcagctt
gacaacccttacattgtgcgcatgatagggatttgtgaagctgagtcctggatgctggtc
atggagatggcagaacttggtccactcaacaaatatttacaacagaacaggcatgtcaag
gataaaaacatcatagagctggttcatcaggtgtctatgggaatgaaatatttggaagag
tgcaattttgtgcacagagatctggctgcaaggaatgtattgctggttactcaacattat
gccaagatcagtgattttggactttctaaagcacttcgtgctgatgaaaactactataag
gcccagacccacggaaagtggcctgtgaagtggtacgctccagaatgcatcaactactac
aagttctccagcaagagtgatgtttggagcttcggagtgttaatgtgggaagcgttttct
tatgggcagaagccatatcggggaatgaaaggcagtgaagtttctgctatgctggagaaa
ggagagaggatggggtgcccaccagggtgtcctagagagatgtacgagctgatgaccctg
tgctggacctatgacgtggagaacaggcctggattcgtagctgtggaactgcggctgcgc
aattactactacgacgtggtgaactaa

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